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  1. Article: Prolotherapy: Potential for the Treatment of Chronic Wounds?

    Siadat, Amir Hossein / Isseroff, Roslyn Rivkah

    Advances in wound care

    2019  Volume 8, Issue 4, Page(s) 160–167

    Abstract: Significance: ...

    Abstract Significance:
    Language English
    Publishing date 2019-04-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2650541-1
    ISSN 2162-1934 ; 2162-1918
    ISSN (online) 2162-1934
    ISSN 2162-1918
    DOI 10.1089/wound.2018.0866
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  2. Article: Antidepressants and the Risk of Psoriasis Induction: A Case-Control Study.

    Sadatmadani, Seyedeh-Fatemeh / Siadat, Amir Hossein / Iraji, Fariba / Alsahebfosoul, Fereshteh

    Advanced biomedical research

    2023  Volume 12, Page(s) 16

    Abstract: Background: Psoriasis (PSO) is a common chronic autoimmune skin disease with a significant psycho-socio-economic burden. Some antidepressants (ADs) such as fluoxetine and bupropion can induce or exacerbate PSO. This study aimed to investigate the ... ...

    Abstract Background: Psoriasis (PSO) is a common chronic autoimmune skin disease with a significant psycho-socio-economic burden. Some antidepressants (ADs) such as fluoxetine and bupropion can induce or exacerbate PSO. This study aimed to investigate the correlation between ADs history before PSO onset, and the risk of PSO induction, in Isfahan province, Iran.
    Materials and methods: In this case-control study, 80 patients with PSO were selected by non-probability sampling method, and 80 healthy individuals were selected using simple random sampling. They were interviewed and medical information was recorded. Chi-square, Mann-Whitney, and Kruskal-Wallis tests for dichotomous or categorical data, and independent-sample t test for continuous data were used. Statistical significance was taken as
    Results: In this case-control study, a total of 160 individuals, 80 participants in each group, were included. The mean age of the total samples was 44.8 ± 16 years. Forty-three percent of the individuals were women. PSO familial history in the cases was significantly higher than the control group (OR = 11.94,
    Conclusions: Past history of ADs in the cases before PSO onset, was higher than the controls, indicating a possible association between ADs and the risk of PSO induction. This study can be effective to pay more attention to the possible complications of ADs and PSO risk factors. Accurate knowledge of PSO risk factors will be useful for better management and morbidity reduction.
    Language English
    Publishing date 2023-01-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2672524-1
    ISSN 2277-9175
    ISSN 2277-9175
    DOI 10.4103/abr.abr_88_21
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  3. Article ; Online: Antidepressants and the risk of psoriasis induction

    Seyedeh-Fatemeh Sadatmadani / Amir Hossein Siadat / Fariba Iraji / Fereshteh Alsahebfosoul

    Advanced Biomedical Research, Vol 12, Iss 1, Pp 16-

    A case–control study

    2023  Volume 16

    Abstract: Background: Psoriasis (PSO) is a common chronic autoimmune skin disease with a significant psycho-socio-economic burden. Some antidepressants (ADs) such as fluoxetine and bupropion can induce or exacerbate PSO. This study aimed to investigate the ... ...

    Abstract Background: Psoriasis (PSO) is a common chronic autoimmune skin disease with a significant psycho-socio-economic burden. Some antidepressants (ADs) such as fluoxetine and bupropion can induce or exacerbate PSO. This study aimed to investigate the correlation between ADs history before PSO onset, and the risk of PSO induction, in Isfahan province, Iran. Materials and Methods: In this case–control study, 80 patients with PSO were selected by non-probability sampling method, and 80 healthy individuals were selected using simple random sampling. They were interviewed and medical information was recorded. Chi-square, Mann–Whitney, and Kruskal–Wallis tests for dichotomous or categorical data, and independent-sample t test for continuous data were used. Statistical significance was taken as P ≤ 0.05. Results: In this case–control study, a total of 160 individuals, 80 participants in each group, were included. The mean age of the total samples was 44.8 ± 16 years. Forty-three percent of the individuals were women. PSO familial history in the cases was significantly higher than the control group (OR = 11.94, P = 0.001). It was revealed that use of ADs by patients before PSO induction, was greater than the controls (OR = 2.78, P = 0.058). Conclusions: Past history of ADs in the cases before PSO onset, was higher than the controls, indicating a possible association between ADs and the risk of PSO induction. This study can be effective to pay more attention to the possible complications of ADs and PSO risk factors. Accurate knowledge of PSO risk factors will be useful for better management and morbidity reduction.
    Keywords antidepressants ; autoimmune dermatologic disease ; depression ; psoriasis ; Medicine ; R ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Pemphigus vegetans misdiagnosed as condylomata acuminata: A case report.

    Siadat, Amir Hossein / Moeine, Reza / Iraji, Fariba / Galehdari, Hamid / Shahriarirad, Reza

    Clinical case reports

    2022  Volume 10, Issue 10, Page(s) e6393

    Abstract: Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetating lesions primarily in the flexures. A 41-year-old male patient presented with pemphigus vegetans highly mimicking condylomata acuminata, which led to mistreatment. ... ...

    Abstract Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetating lesions primarily in the flexures. A 41-year-old male patient presented with pemphigus vegetans highly mimicking condylomata acuminata, which led to mistreatment. Careful analysis of clinical and laboratory findings enabled us to reach a correct diagnosis and successful treatment.
    Language English
    Publishing date 2022-10-17
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6393
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  5. Article ; Online: Pemphigus vegetans misdiagnosed as condylomata acuminata

    Amir Hossein Siadat / Reza Moeine / Fariba Iraji / Hamid Galehdari / Reza Shahriarirad

    Clinical Case Reports, Vol 10, Iss 10, Pp n/a-n/a (2022)

    A case report

    2022  

    Abstract: Abstract Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetating lesions primarily in the flexures. A 41‐year‐old male patient presented with pemphigus vegetans highly mimicking condylomata acuminata, which led to ... ...

    Abstract Abstract Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetating lesions primarily in the flexures. A 41‐year‐old male patient presented with pemphigus vegetans highly mimicking condylomata acuminata, which led to mistreatment. Careful analysis of clinical and laboratory findings enabled us to reach a correct diagnosis and successful treatment.
    Keywords condylomata acuminata ; diagnosis ; pemphigus vegetans ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Cutaneous leukocytoclastic vasculitis secondary to COVID‐19 infection

    Fariba Iraji / Hamid Galehdari / Amir Hossein Siadat / Safoura Bokaei Jazi

    Clinical Case Reports, Vol 9, Iss 2, Pp 830-

    A case report

    2021  Volume 834

    Abstract: Abstract COVID‐19 is a novel disease that mostly affects the respiratory system but as the number of cases is rising significantly around the world, more extra‐respiratory manifestations are being reported among which are various dermatologic ... ...

    Abstract Abstract COVID‐19 is a novel disease that mostly affects the respiratory system but as the number of cases is rising significantly around the world, more extra‐respiratory manifestations are being reported among which are various dermatologic manifestations.
    Keywords COVID‐19 ; cutaneous vasculitis ; leukocytoclastic ; SARS‐CoV‐2 ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
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  7. Article ; Online: Comparison between "5% minoxidil plus 2% flutamide" solution vs. "5% minoxidil" solution in the treatment of androgenetic alopecia.

    Faghihi, Gita / Iraji, Fariba / Siadat, Amir Hossein / Saber, Mina / Jelvan, Minoo / Hoseyni, Maedeh Sadat

    Journal of cosmetic dermatology

    2022  Volume 21, Issue 10, Page(s) 4447–4453

    Abstract: Background: Androgenetic alopecia is defined as a patterned hair loss resulting from the effect of androgen on hair follicles and characterized by non-scarring, progressive miniaturization of the hair follicles. Minoxidil and finasteride are regarded as ...

    Abstract Background: Androgenetic alopecia is defined as a patterned hair loss resulting from the effect of androgen on hair follicles and characterized by non-scarring, progressive miniaturization of the hair follicles. Minoxidil and finasteride are regarded as the first-line treatments with antiandrogens and flutamide are considered as the alternative choices. In the current study, we evaluated the efficacy of combination therapy with topical 2%flutamide plus 5% minoxidil vs. %5 minoxidil alone in the treatment of the androgenetic alopecia.
    Material and methods: This was a randomized, double-blinded clinical trial in 40 patients with androgenetic alopecia. Patients were randomized to receive either topical minoxidil vs. topical flutamide plus minoxidil for 6 months. At the end of study, patients were compared regarding mean hair density and mean hair thickness and patient's satisfaction. Collected data were analyzed using t-test, Ki square, and Kolmogorov-Smirnov tests.
    Results: Topical flutamide plus minoxidil solution was significantly more effective than minoxidil in terms of hair density, hair thickness, and patient's satisfaction (p < 0.05).
    Conclusion: Topical hydroalcoholic solution of flutamide plus minoxidil may be promising treatment for the androgenetic alopecia. To better evaluate the efficacy of topical flutamide, more prolonged studies with higher number of patients and use of different vehicles and different ingredients are recommended.
    MeSH term(s) Humans ; Minoxidil ; Flutamide/therapeutic use ; Treatment Outcome ; Alopecia/diagnosis ; Alopecia/drug therapy ; Alopecia/chemically induced ; Finasteride ; Administration, Topical
    Chemical Substances Minoxidil (5965120SH1) ; Flutamide (76W6J0943E) ; Finasteride (57GNO57U7G)
    Language English
    Publishing date 2022-02-18
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.14788
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6539: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Cutaneous leukocytoclastic vasculitis secondary to COVID-19 infection: A case report.

    Iraji, Fariba / Galehdari, Hamid / Siadat, Amir Hossein / Bokaei Jazi, Safoura

    Clinical case reports

    2020  Volume 9, Issue 2, Page(s) 830–834

    Abstract: COVID-19 is a novel disease that mostly affects the respiratory system but as the number of cases is rising significantly around the world, more extra-respiratory manifestations are being reported among which are various dermatologic manifestations. ...

    Abstract COVID-19 is a novel disease that mostly affects the respiratory system but as the number of cases is rising significantly around the world, more extra-respiratory manifestations are being reported among which are various dermatologic manifestations.
    Language English
    Publishing date 2020-12-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.3596
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  9. Article: The significance of microbiome in personalized medicine.

    Behrouzi, Ava / Nafari, Amir Hossein / Siadat, Seyed Davar

    Clinical and translational medicine

    2019  Volume 8, Issue 1, Page(s) 16

    Abstract: Considering the important role of microbiome, many of current investigations have focused on its beneficial aspects. Although, research explores new dimensions of the impact of microbiome and examines the differences in patients and healthy individuals ... ...

    Abstract Considering the important role of microbiome, many of current investigations have focused on its beneficial aspects. Although, research explores new dimensions of the impact of microbiome and examines the differences in patients and healthy individuals for identifying biomarker patterns, but limited information is available, and investigation in this field seems to be of great value. On the other hand, new therapeutic approaches, called personalized medicine, have opened a new window in medical science, and the association between microbiome and personalized medicine seems to be one of the most interesting aspects of the subsequent research, and has a pivotal perspective on the treatment of diseases such as cancer. Accordingly, given the novelty of the relationship between these two axes, there are very few studies in this regard. The presence of specific strains may have the ability to modulate cancer progression and therapeutics; this increases the likelihood of precision medicine in relation to microbiota, in terms of treatment and prognosis, and therefore, microbiota is a next generation medicine and may develop a novel therapeutic action in this field.
    Language English
    Publishing date 2019-05-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2697013-2
    ISSN 2001-1326
    ISSN 2001-1326
    DOI 10.1186/s40169-019-0232-y
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  10. Article: Oral Pulse Betamethasone, Methotrexate, and Combination Therapy to Treat Severe Alopecia Areata: A Randomized, Double-blind, Placebo-controlled, Clinical Trial.

    Asilian, Ali / Fatemi, Farahnaz / Ganjei, Zakiye / Siadat, Amir Hossein / Mohaghegh, Fatemeh / Siavash, Mansour

    Iranian journal of pharmaceutical research : IJPR

    2021  Volume 20, Issue 1, Page(s) 267–273

    Abstract: The purpose of this study is to compare oral betamethasone pulse therapy, methotrexate therapy and a combination of the two for patients with Alopecia Areata (AA) as an autoimmune disorder. In this study, 36 patients with severe AA were selected and ... ...

    Abstract The purpose of this study is to compare oral betamethasone pulse therapy, methotrexate therapy and a combination of the two for patients with Alopecia Areata (AA) as an autoimmune disorder. In this study, 36 patients with severe AA were selected and classified into three groups of 12: 1- Oral betamethasone therapy (3 mg, once a week) with placebo; 2- Oral methotrexate (15 mg, once a week) with placebo; and 3- A combination of methotrexate (15 mg, once a week) and betamethasone (3 mg, once a week). The Severity Alopecia Tool (SALT) was used to measure improvements in the lesions through photographs, and the patients also rated their condition on the Visual Analogue Scale (VAS). Assessments were performed, and the results were compared at baseline and then at intervals of three months for nine months. The demographics and SALT score were similar in the three groups (
    Language English
    Publishing date 2021-07-09
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2578271-X
    ISSN 1726-6890 ; 1735-0328 ; 1735-0328
    ISSN (online) 1726-6890 ; 1735-0328
    ISSN 1735-0328
    DOI 10.22037/ijpr.2020.113868.14536
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