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  1. Article ; Online: Combined high flow nasal cannula and negative pressure ventilation as a novel respiratory approach in a patient with acute respiratory failure and limb-girdle muscular dystrophy.

    Imitazione, Pasquale / Annunziata, Anna / Lanza, Maurizia / Fiorentino, Giuseppe

    Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology

    2021  Volume 40, Issue 2, Page(s) 101–104

    Abstract: We describe the case of a 56-year-old-man with limb-girdle muscular dystrophy affected by acute hypercapnic failure secondary to pneumonia treated with high flow nasal cannula, intermittent abdominal ventilation, and negative pressure ventilation. The ... ...

    Abstract We describe the case of a 56-year-old-man with limb-girdle muscular dystrophy affected by acute hypercapnic failure secondary to pneumonia treated with high flow nasal cannula, intermittent abdominal ventilation, and negative pressure ventilation. The patient did not tolerate noninvasive positive pressure ventilation and refused invasive ventilation and tracheostomy. We successfully experienced a novel approach combining high flow nasal cannula with cycles of intermittent abdominal pressure ventilation and negative pressure ventilation.
    MeSH term(s) Cannula ; Humans ; Middle Aged ; Muscular Dystrophies, Limb-Girdle/complications ; Muscular Dystrophies, Limb-Girdle/therapy ; Noninvasive Ventilation ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy
    Language English
    Publishing date 2021-06-30
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 2102328-1
    ISSN 2532-1900 ; 1128-2460
    ISSN (online) 2532-1900
    ISSN 1128-2460
    DOI 10.36185/2532-1900-049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Alpha-1 antitrypsin deficiency in the elderly: a case report.

    Annunziata, Anna / Lanza, Maurizia / Coppola, Antonietta / Fiorentino, Giuseppe

    Journal of medical case reports

    2021  Volume 15, Issue 1, Page(s) 231

    Abstract: Background: Generally, alpha-1 antitrypsin deficiency (AATD) is suspected in young patients with pulmonary emphysema or chronic obstructive pulmonary disease (COPD). Patients often suffer from diagnostic gaps and are misdiagnosed with chronic ... ...

    Abstract Background: Generally, alpha-1 antitrypsin deficiency (AATD) is suspected in young patients with pulmonary emphysema or chronic obstructive pulmonary disease (COPD). Patients often suffer from diagnostic gaps and are misdiagnosed with chronic obstructive pulmonary disease (COPD), asthma, and airway hyperresponsiveness (AHR), as AATD may present with nonspecific respiratory symptoms. It is never too late to suspect AATD, especially in a patient with an unusual medical history. In recent years, evidence is beginning to emerge that there may be value in identifying and treating patients who do not already have deterioration of functional parameters.
    Case presentation: We describe a case of a 69-year-old Caucasian female patient, late diagnosis of AATD, with both severe bronchial hyperreactivity and numerous exacerbations due to the peculiar clinical history and the presence of a rare mutation; although not presenting forced expiratory volume in 1 second (FEV
    Conclusion: AATD should always be suspected. The Alpha-1 Foundation recommendations for the diagnosis and management of AATD in adult patients indicate that treatment should be provided for patients with FEV
    MeSH term(s) Adult ; Aged ; Asthma ; Female ; Humans ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Emphysema ; alpha 1-Antitrypsin Deficiency/complications ; alpha 1-Antitrypsin Deficiency/diagnosis ; alpha 1-Antitrypsin Deficiency/drug therapy
    Language English
    Publishing date 2021-05-10
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-021-02847-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Alpha-1 antitrypsin deficiency in the elderly

    Anna Annunziata / Maurizia Lanza / Antonietta Coppola / Giuseppe Fiorentino

    Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-

    a case report

    2021  Volume 4

    Abstract: Abstract Background Generally, alpha-1 antitrypsin deficiency (AATD) is suspected in young patients with pulmonary emphysema or chronic obstructive pulmonary disease (COPD). Patients often suffer from diagnostic gaps and are misdiagnosed with chronic ... ...

    Abstract Abstract Background Generally, alpha-1 antitrypsin deficiency (AATD) is suspected in young patients with pulmonary emphysema or chronic obstructive pulmonary disease (COPD). Patients often suffer from diagnostic gaps and are misdiagnosed with chronic obstructive pulmonary disease (COPD), asthma, and airway hyperresponsiveness (AHR), as AATD may present with nonspecific respiratory symptoms. It is never too late to suspect AATD, especially in a patient with an unusual medical history. In recent years, evidence is beginning to emerge that there may be value in identifying and treating patients who do not already have deterioration of functional parameters. Case presentation We describe a case of a 69-year-old Caucasian female patient, late diagnosis of AATD, with both severe bronchial hyperreactivity and numerous exacerbations due to the peculiar clinical history and the presence of a rare mutation; although not presenting forced expiratory volume in 1 second (FEV1) between 30 and 65%, the patient was treated with alpha-1 antitrypsin (AAT) augmentation therapy and achieved clinical and functional improvement. Conclusion AATD should always be suspected. The Alpha-1 Foundation recommendations for the diagnosis and management of AATD in adult patients indicate that treatment should be provided for patients with FEV1 between 30 and 65%. It may be useful to evaluate and treat patients based on clinical symptoms, even outside the established parameters, in particular cases.
    Keywords Alpha-1 antitrypsin ; Replacement therapy ; Lung disease ; Asthma ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Unconventional use of high-flow nasal cannula in acute exacerbation of idiopathic pulmonary fibrosis with high levels of hypercapnia.

    Fiorentino, Giuseppe / Lanza, Maurizia / Spinelli, Sara / Imitazione, Pasquale / Annunziata, Anna

    Anaesthesiology intensive therapy

    2020  Volume 52, Issue 1, Page(s) 78–82

    MeSH term(s) Cannula ; Humans ; Hypercapnia/therapy ; Idiopathic Pulmonary Fibrosis/complications ; Idiopathic Pulmonary Fibrosis/therapy ; Male ; Middle Aged ; Oxygen Inhalation Therapy/methods
    Language English
    Publishing date 2020-03-12
    Publishing country Poland
    Document type Case Reports ; Letter
    ISSN 1731-2531
    ISSN (online) 1731-2531
    DOI 10.5114/ait.2020.93713
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Only those who attempt the absurd will reach the impossible. High-flow nasal cannula oxygen therapy alone during weaning after extubation in a patient with tuberous sclerosis complex and lymphangioleiomyomatosis.

    Lanza, Maurizia / Imitazione, Pasquale / Musella, Salvatore / Annunziata, Anna / Fiorentino, Giuseppe

    Anaesthesiology intensive therapy

    2020  Volume 52, Issue 3, Page(s) 263–266

    MeSH term(s) Airway Extubation ; Female ; Humans ; Lymphangioleiomyomatosis/complications ; Lymphangioleiomyomatosis/diagnostic imaging ; Oxygen Inhalation Therapy/methods ; Status Epilepticus/complications ; Tomography, X-Ray Computed ; Tuberous Sclerosis/complications ; Tuberous Sclerosis/diagnostic imaging ; Ventilator Weaning/methods ; Young Adult
    Language English
    Publishing date 2020-09-01
    Publishing country Poland
    Document type Case Reports ; Letter
    ISSN 1731-2531
    ISSN (online) 1731-2531
    DOI 10.5114/ait.2020.97648
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pulmonary Embolism in Covid-19: Coagulation Parameters, Close Monitoring to Prevent?

    Annunziata, Anna / Imitazione, Pasquale / Polistina, Giorgio Emanuele / Lanza, Maurizia / Coppola, Antonietta / Fiorentino, Giuseppe

    Turkish thoracic journal

    2020  Volume 21, Issue 4, Page(s) 287–288

    Keywords covid19
    Language English
    Publishing date 2020-06-10
    Publishing country Turkey
    Document type Letter
    ISSN 2149-2530
    ISSN (online) 2149-2530
    DOI 10.5152/TurkThoracJ.2020.20067
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  7. Article: Alpha-1 Antitrypsin Deficiency: Home Therapy.

    Annunziata, Anna / Lanza, Maurizia / Coppola, Antonietta / Andreozzi, Paolo / Spinelli, Sara / Fiorentino, Giuseppe

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 575402

    Abstract: While available in only a few countries, home therapy is a possible strategy for the treatment of alpha-1 antitrypsin deficiency. We want to describe our experience in the management of human alpha-1 antitrypsin using home care intravenous augmentation ... ...

    Abstract While available in only a few countries, home therapy is a possible strategy for the treatment of alpha-1 antitrypsin deficiency. We want to describe our experience in the management of human alpha-1 antitrypsin using home care intravenous augmentation therapy during this emergency period caused by SARS-CoV2 infection. We assessed the safety of the home treatment and the quality of life of patients enrolled in the program.
    Language English
    Publishing date 2021-04-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.575402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Acute Respiratory Failure in COVID-19 Pneumoniae: The Best Interface for an Optimal Management - A South Italian Experience.

    Imitazione, Pasquale / Polistina, Giorgio Emanuele / Annunziata, Anna / Di Spirito, Valentina / Lanza, Maurizia / Fiorentino, Giuseppe

    Turkish thoracic journal

    2020  Volume 21, Issue 4, Page(s) 289–290

    Keywords covid19
    Language English
    Publishing date 2020-06-10
    Publishing country Turkey
    Document type Letter
    ISSN 2149-2530
    ISSN (online) 2149-2530
    DOI 10.5152/TurkThoracJ.2020.20071
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  9. Article ; Online: The Role of HFNC

    Fiorentino, Giuseppe / Lanza, Maurizia / Annunziata, Anna / Imitazione, Pasquale

    Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients ; page 159-165 ; ISBN 9783030556204 9783030556211

    2020  

    Keywords covid19
    Publisher Springer International Publishing
    Publishing country us
    Document type Article ; Online
    DOI 10.1007/978-3-030-55621-1_17
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: A Rare Evolution to Pneumopericardium in Patient with COVID-19 Pneumonia Treated with High Flow Nasal Cannula.

    Polistina, Giorgio Emanuele / Lanza, Maurizia / Di Somma, Camilla / Annunziata, Anna / Fiorentino, Giuseppe

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 10

    Abstract: Infection with severe acute respiratory syndrome coronavirus 2 causes coronavirus disease 2019 (COVID-19) which was revealed an official pandemic by the World Health Organization on 11 March 2020. The current pandemic, the third of this decade, is the ... ...

    Abstract Infection with severe acute respiratory syndrome coronavirus 2 causes coronavirus disease 2019 (COVID-19) which was revealed an official pandemic by the World Health Organization on 11 March 2020. The current pandemic, the third of this decade, is the worst in terms of suffering and deaths related. COVID-19 represents an unprecedented challenge for medical communities and patients around the world. High-resolution computed tomography of the chest (HRCT) is a fundamental tool in both management and diagnosis of the disease. Imaging plays an essential role in the diagnosis of all the manifestations of the disease and its complications and the correct use and interpretation of imaging tests are essential. Pneumomediastinum has been reported rarely in COVID-19 patients. We were one of the first groups to share our experiences in uncommon parenchymal complications of COVID-19 with spontaneous pneumothorax and pneumomediastinum, but also with new-onset bronchiectasis and cysts. A finding of pneumopericardium is also unusual. We hereby report a rare case of spontaneous pneumopericardium in a patient with COVID-19 pneumonia treated only with a high-flow nasal cannula (HFNC).
    MeSH term(s) COVID-19 ; Cannula ; Humans ; Pandemics ; Pneumopericardium/diagnostic imaging ; Pneumopericardium/etiology ; SARS-CoV-2
    Language English
    Publishing date 2021-10-18
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57101122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
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