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  1. Article ; Online: A new emerging zoonotic virus of concern

    José Millán-Oñate

    Infectio, Vol 24, Iss 3, Pp 187-

    the 2019 novel Coronavirus (SARS CoV-2)

    2020  Volume 192

    Abstract: Revisamos aquí el origen, características del brote y la epidemiología del nuevo Coronavirus (2019nCoV) responsable de una nueva enfermedad por coronavirus (COVID-19). Una rápida respuesta de las autoridades de salud mundiales está en marcha y se ha ... ...

    Abstract Revisamos aquí el origen, características del brote y la epidemiología del nuevo Coronavirus (2019nCoV) responsable de una nueva enfermedad por coronavirus (COVID-19). Una rápida respuesta de las autoridades de salud mundiales está en marcha y se ha hecho un llamado urgente para colaboración científica internacional. Las lecciones aprendidas de brotes previos con agentes virales similares han aumentado las capacidades para contener y controlar estas amenazas recurrentes a la salud global.
    Keywords coronavirus ; epidemias ; zoonosis ; viajeros ; colombia ; Therapeutics. Pharmacology ; RM1-950 ; Infectious and parasitic diseases ; RC109-216 ; covid19
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Asociación Colombiana de Infectología
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin.

    Millán-Oñate, José / Millan, William / Mendoza, Luis Alfonso / Sánchez, Carlos Guillermo / Fernandez-Suarez, Hugo / Bonilla-Aldana, D Katterine / Rodríguez-Morales, Alfonso J

    Annals of clinical microbiology and antimicrobials

    2020  Volume 19, Issue 1, Page(s) 16

    Abstract: Background: COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including ... ...

    Abstract Background: COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including chloroquine. We report here the clinical features and therapeutic course of the first reported patient with confirmed COVID-19 pneumonia that recovered in Colombia, after the use of chloroquine and clarithromycin.
    Case presentation: A 34-year-old male, returning from Spain, presented with complaints of fever, and cough, and class-II obesity, being hospitalized. The respiratory viruses and bacteria tested by FilmArray
    Conclusions: Our patient improved significantly. This and other COVID-19 cases are urgently demanding results from clinical trials that support evidence-based therapeutical approaches to this pandemic and the clinical management of patients, especially those at critical care.
    MeSH term(s) Adult ; Betacoronavirus ; Chloroquine/therapeutic use ; Clarithromycin/therapeutic use ; Colombia ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Humans ; Male ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/drug therapy
    Chemical Substances Chloroquine (886U3H6UFF) ; Clarithromycin (H1250JIK0A)
    Keywords covid19
    Language English
    Publishing date 2020-04-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2097873-X
    ISSN 1476-0711 ; 1476-0711
    ISSN (online) 1476-0711
    ISSN 1476-0711
    DOI 10.1186/s12941-020-00358-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: COVID-19 associated mucormycosis: the urgent need to reconsider the indiscriminate use of immunosuppressive drugs.

    Rodriguez-Morales, Alfonso J / Sah, Ranjit / Millan-Oñate, Jose / Gonzalez, Angel / Montenegro-Idrogo, Juan J / Scherger, Sias / Franco-Paredes, Carlos / Henao-Martínez, Andrés F

    Therapeutic advances in infectious disease

    2021  Volume 8, Page(s) 20499361211027065

    Language English
    Publishing date 2021-06-18
    Publishing country England
    Document type Editorial
    ZDB-ID 2728410-4
    ISSN 2049-937X ; 2049-9361
    ISSN (online) 2049-937X
    ISSN 2049-9361
    DOI 10.1177/20499361211027065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin

    Millán-Oñate, José / Millan, William / Mendoza, Luis Alfonso / Sánchez, Carlos Guillermo / Fernandez-Suarez, Hugo / Bonilla-Aldana, D. Katterine / Rodríguez-Morales, Alfonso J.

    Annals of Clinical Microbiology and Antimicrobials

    2020  Volume 19, Issue 1

    Keywords Microbiology (medical) ; Infectious Diseases ; General Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2097873-X
    ISSN 1476-0711
    ISSN 1476-0711
    DOI 10.1186/s12941-020-00358-y
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin

    Millán-Oñate, José / Millan, William / Mendoza, Luis Alfonso / Sánchez, Carlos Guillermo / Fernandez-Suarez, Hugo / Bonilla-Aldana, D Katterine / Rodríguez-Morales, Alfonso J

    Ann Clin Microbiol Antimicrob

    Abstract: BACKGROUND: COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including ... ...

    Abstract BACKGROUND: COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including chloroquine. We report here the clinical features and therapeutic course of the first reported patient with confirmed COVID-19 pneumonia that recovered in Colombia, after the use of chloroquine and clarithromycin. CASE PRESENTATION: A 34-year-old male, returning from Spain, presented with complaints of fever, and cough, and class-II obesity, being hospitalized. The respiratory viruses and bacteria tested by FilmArray® PCR were negative. Two days later, clarithromycin was started because the patient was suspected as community-acquired pneumonia. At the third day, the rRT-PCR confirmed the SARS-CoV-2 infection. A day later, chloroquine was started because of that. His chest computed tomography was performed and showed bilateral multifocal ground-glass opacities with consolidation, which suggested viral pneumonia as a differential diagnosis. Progressively his clinical condition improved and at day 9, patient rRT-PCR for SARS-CoV-2 became negative. The patient was discharged and isolated at home per 14 days. CONCLUSIONS: Our patient improved significantly. This and other COVID-19 cases are urgently demanding results from clinical trials that support evidence-based therapeutical approaches to this pandemic and the clinical management of patients, especially those at critical care.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #116464
    Database COVID19

    Kategorien

  6. Article ; Online: Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin

    Millán-Oñate, José / Millan, William / Mendoza, Luis Alfonso / Sánchez, Carlos Guillermo / Fernandez-Suarez, Hugo / Bonilla-Aldana, D. Katterine / Rodríguez-Morales, Alfonso J.

    Annals of clinical microbiology and antimicrobials, 19(1):16

    2020  

    Abstract: BACKGROUND: COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including ... ...

    Abstract BACKGROUND: COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including chloroquine. We report here the clinical features and therapeutic course of the first reported patient with confirmed COVID-19 pneumonia that recovered in Colombia, after the use of chloroquine and clarithromycin. CASE REPRESENTATION: A 34-year-old male, returning from Spain, presented with complaints of fever, and cough, and class-II obesity, being hospitalized. The respiratory viruses and bacteria tested by FilmArray® PCR were negative. Two days later, clarithromycin was started because the patient was suspected as community-acquired pneumonia. At the third day, the rRT-PCR confirmed the SARS-CoV-2 infection. A day later, chloroquine was started because of that. His chest computed tomography was performed and showed bilateral multifocal ground-glass opacities with consolidation, which suggested viral pneumonia as a differential diagnosis. Progressively his clinical condition improved and at day 9, patient rRT-PCR for SARS-CoV-2 became negative. The patient was discharged and isolated at home per 14 days. CONCLUSIONS: Our patient improved significantly. This and other COVID-19 cases are urgently demanding results from clinical trials that support evidence-based therapeutical approaches to this pandemic and the clinical management of patients, especially those at critical care.
    Keywords COVID-19 ; Chloroquine ; Coronavirus Disease 2019 ; Latin America ; Severe Acute Respiratory Syndrome Coronavirus 2 ; Colombia ; SARS-CoV-2 ; covid19
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A new emerging zoonotic virus of concern: The 2019 novel Coronavirus (COVID-19)/ Un nuevo virus zoonótico emergente de preocupación: El Coronavirus novel 2019

    Millán-Oñate, José / Rodriguez-Morales, Alfonso J. / Camacho-Moreno, German / Mendoza-Ramírez, Henry / Rodríguez-Sabogal, Iván Arturo / Álvarez-Moreno, Carlos

    Infectio

    Abstract: We review here the origin, outbreak characteristics and main epidemiological features of the novel Coronavirus (2019nCoV) responsible of a new coronavirus disease (COVID-19). Rapid global health authorities’ responses are now in course and international ... ...

    Abstract We review here the origin, outbreak characteristics and main epidemiological features of the novel Coronavirus (2019nCoV) responsible of a new coronavirus disease (COVID-19). Rapid global health authorities’ responses are now in course and international scientific collaboration is urgently need. Previous outbreaks experiences with similar viral agents have increased the capacity to containment and control of these recurrent health menaces.
    Keywords covid19
    Publisher WHO
    Document type Article ; Online
    Note WHO #Covidence: #87973
    DOI 10.22354/in.v24i3.848
    Database COVID19

    Kategorien

  8. Article: A new emerging zoonotic virus of concern: the 2019 novel Coronavirus (SARS CoV-2)/ Un nuevo virus zoonótico emergente de preocupación: el Coronavirus novel 2019

    Millán-Oñate, José / Rodriguez-Morales, Alfonso J. / Camacho-Moreno, German / Mendoza-Ramírez, Henry / Rodríguez-Sabogal, Iván Arturo / Álvarez-Moreno, Carlos

    Infectio

    Abstract: Abstract We review here the origin, outbreak characteristics and main epidemiological features of the novel Coronavirus (2019nCoV) responsible of a new coronavirus disease (COVID-19). Rapid global health authorities' responses are now in course and ... ...

    Abstract Abstract We review here the origin, outbreak characteristics and main epidemiological features of the novel Coronavirus (2019nCoV) responsible of a new coronavirus disease (COVID-19). Rapid global health authorities' responses are now in course and international scientific collaboration is urgently need. Previous outbreaks experiences with similar viral agents have increased the capacity to containment and control of these recurrent health menaces.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #87973
    Database COVID19

    Kategorien

  9. Article ; Online: Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin

    José Millán-Oñate / William Millan / Luis Alfonso Mendoza / Carlos Guillermo Sánchez / Hugo Fernandez-Suarez / D. Katterine Bonilla-Aldana / Alfonso J. Rodríguez-Morales

    Annals of Clinical Microbiology and Antimicrobials, Vol 19, Iss 1, Pp 1-

    2020  Volume 9

    Abstract: Abstract Background COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, ... ...

    Abstract Abstract Background COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including chloroquine. We report here the clinical features and therapeutic course of the first reported patient with confirmed COVID-19 pneumonia that recovered in Colombia, after the use of chloroquine and clarithromycin. Case presentation A 34-year-old male, returning from Spain, presented with complaints of fever, and cough, and class-II obesity, being hospitalized. The respiratory viruses and bacteria tested by FilmArray® PCR were negative. Two days later, clarithromycin was started because the patient was suspected as community-acquired pneumonia. At the third day, the rRT-PCR confirmed the SARS-CoV-2 infection. A day later, chloroquine was started because of that. His chest computed tomography was performed and showed bilateral multifocal ground-glass opacities with consolidation, which suggested viral pneumonia as a differential diagnosis. Progressively his clinical condition improved and at day 9, patient rRT-PCR for SARS-CoV-2 became negative. The patient was discharged and isolated at home per 14 days. Conclusions Our patient improved significantly. This and other COVID-19 cases are urgently demanding results from clinical trials that support evidence-based therapeutical approaches to this pandemic and the clinical management of patients, especially those at critical care.
    Keywords Coronavirus Disease 2019 (COVID-19) ; Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) ; Chloroquine ; Colombia ; Latin America ; Therapeutics. Pharmacology ; RM1-950 ; Infectious and parasitic diseases ; RC109-216 ; Microbiology ; QR1-502 ; covid19
    Subject code 610
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Multinational prospective cohort study of incidence and risk factors for central line-associated bloodstream infections in ICUs of 8 Latin American countries.

    Rosenthal, Victor Daniel / Jin, Zhilin / Valderrama-Beltran, Sandra Liliana / Gualtero, Sandra Milena / Linares, Claudia Yaneth / Aguirre-Avalos, Guadalupe / Mijangos-Méndez, Julio Cesar / Ibarra-Estrada, Miguel Ángel / Jiménez-Alvarez, Luisa Fernanda / Reyes, Lidia Patricia / Alvarez-Moreno, Carlos Arturo / Zuniga-Chavarria, Maria Adelia / Quesada-Mora, Ana Marcela / Gomez, Katherine / Alarcon, Johana / Millan-Oñate, Jose / Aguilar-de-Moros, Daisy / Castaño-Guerrero, Elizabeth / Córdoba, Judith /
    Sassoe-Gonzalez, Alejandro / Millán-Castillo, Claudia Marisol / Leyva-Xotlanihua, Lissette / Aguilar-Moreno, Lina Alejandra / Bravo-Ojeda, Juan Sebastian / Gutierrez-Tobar, Ivan Felipe / Aleman-Bocanegra, Mary Cruz / Echazarreta-Martínez, Clara Veronica / Flores-Sánchez, Belinda Mireya / Cano-Medina, Yuliana Andrea / Chapeta-Parada, Edwin Giovannny / Gonzalez-Niño, Rafael Antonio / Villegas-Mota, Maria Isabel / Montoya-Malváez, Mildred / Cortés-Vázquez, Miguel Ángel / Medeiros, Eduardo Alexandrino / Fram, Dayana / Vieira-Escudero, Daniela / Dueñas, Lourdes / Carreazo, Nilton Yhuri / Salgado, Estuardo / Yin, Ruijie

    American journal of infection control

    2023  Volume 51, Issue 10, Page(s) 1114–1119

    Abstract: Background: Our objective was to identify central line (CL)-associated bloodstream infections (CLABSI) rates and risk factors in Latin-America.: Methods: From January 1, 2014 to February 10, 2022, we conducted a multinational multicenter prospective ... ...

    Abstract Background: Our objective was to identify central line (CL)-associated bloodstream infections (CLABSI) rates and risk factors in Latin-America.
    Methods: From January 1, 2014 to February 10, 2022, we conducted a multinational multicenter prospective cohort study in 58 ICUs of 34 hospitals in 21 cities in 8 Latin American countries (Argentina, Brazil, Colombia, Costa Rica, Dominican Republic, Ecuador, Mexico, Panama). We applied multiple-logistic regression. Outcomes are shown as adjusted-odds ratios (aOR).
    Results: About 29,385 patients were hospitalized during 92,956 days, acquired 400 CLABSIs, and pooled CLABSI rate was 4.30 CLABSIs per 1,000 CL-days. We analyzed following 10 variables: Gender, age, length of stay (LOS) before CLABSI acquisition, CL-days before CLABSI acquisition, CL-device utilization (DU) ratio, CL-type, tracheostomy use, hospitalization type, intensive care unit (ICU) type, and facility ownership, Following variables were independently associated with CLABSI: LOS before CLABSI acquisition, rising risk 3% daily (aOR=1.03;95%CI=1.02-1.04; P < .0001); number of CL-days before CLABSI acquisition, rising risk 4% per CL-day (aOR=1.04;95%CI=1.03-1.05; P < .0001); publicly-owned facility (aOR=2.33;95%CI=1.79-3.02; P < .0001). ICU with highest risk was medical-surgical (aOR=2.61;95%CI=1.41-4.81; P < .0001). CL with the highest risk were femoral (aOR=2.71;95%CI=1.61-4.55; P < .0001), and internal-jugular (aOR=2.62;95%CI=1.82-3.79; P < .0001). PICC (aOR=1.25;95%CI=0.63-2.51; P = .52) was not associated with CLABSI risk.
    Conclusions: Based on these findings it is suggested to focus on reducing LOS, CL-days, using PICC instead of femoral or internal-jugular; and implementing evidence-based CLABSI prevention recommendations.
    MeSH term(s) Humans ; Cross Infection/prevention & control ; Catheter-Related Infections/prevention & control ; Prospective Studies ; Latin America/epidemiology ; Incidence ; Intensive Care Units ; Risk Factors ; Sepsis/epidemiology ; Catheterization, Central Venous/adverse effects
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2023.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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