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  1. Article: The history and epidemiology of Middle East respiratory syndrome corona virus.

    Al-Osail, Aisha M / Al-Wazzah, Marwan J

    Multidisciplinary respiratory medicine

    2017  Volume 12, Page(s) 20

    Abstract: Corona viruses cause common cold, and infections caused by corona viruses are generally self-resolving. During the last 4 years, corona viruses have become the most important viruses worldwide because of the occurrence of several recent deaths caused by ... ...

    Abstract Corona viruses cause common cold, and infections caused by corona viruses are generally self-resolving. During the last 4 years, corona viruses have become the most important viruses worldwide because of the occurrence of several recent deaths caused by corona viruses in Saudi Arabia. Spread of the infection occurred worldwide; however, most cases of mortality have occurred in the Middle East. Owing to the predominance of outbreaks in the Middle Eastern countries, the virus was renamed a Middle East respiratory syndrome corona virus (MERS-CoV) by the Corona virus Study Group. The Center for Diseases Control and Prevention and World Health Organization maintain a website that is updated frequently with new cases of MERS-CoV infection. In this review, we describe the history and epidemiology of this novel virus. Studies of the genetics and molecular mechanisms of this virus are expected to facilitate the development of vaccines in the future.
    Keywords covid19
    Language English
    Publishing date 2017-08-07
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2677839-7
    ISSN 2049-6958 ; 1828-695X
    ISSN (online) 2049-6958
    ISSN 1828-695X
    DOI 10.1186/s40248-017-0101-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Hodgkin's Lymphoma as a Multiloculated Lung Cavity Lesion.

    Al-Osail, Aisha M / Al-Saif, Hind S / Al-Hajri, Mashail M / Al-Zuhair, Hajer M / Al-Abdulhadi, Deemah A / Al-Osail, Emad M / Al-Hajri, Sarah M

    The Gulf journal of oncology

    2017  Volume 1, Issue 24, Page(s) 61–65

    Abstract: Background: Pulmonary manifestation of Hodgkin's lymphoma is common, and recently, single and/or multiple lung cavities with air-fluid levels has been reported as a primary manifestation of Hodgkin's lymphoma. However, the unusual presentation of the ... ...

    Abstract Background: Pulmonary manifestation of Hodgkin's lymphoma is common, and recently, single and/or multiple lung cavities with air-fluid levels has been reported as a primary manifestation of Hodgkin's lymphoma. However, the unusual presentation of the lung cavity itself has not been previously reported for Hodgkin's lymphoma, especially as the first presentation of the disease.
    Case presentation: We report a 16-year-old male who presented to the emergency department with chief complaints of fever, unintentional 10-kilogram weight loss, a productive cough and pulmonary cavity for investigation. The patient's CT scan indicated multiloculated cavity lesions in the middle lobe with an air-fluid level and multiple enlarged mediastinal lymph nodes, which have not been previously reported as a primary presentation for Hodgkin's lymphoma or in the histopathology of the nodular sclerosing type of classical Hodgkin's lymphoma.
    Conclusion: Pulmonary manifestation of Hodgkin's lymphoma has already been reported and must be part of the differential diagnosis of lung cavity lesions, even if the likelihood is low based on previous reports, especially in younger individuals. Multiloculated lung cavities can be the first presentation of Hodgkin's lymphoma.
    MeSH term(s) Adolescent ; Hodgkin Disease/pathology ; Humans ; Lung Neoplasms/pathology ; Male
    Language English
    Publishing date 2017-08-29
    Publishing country Kuwait
    Document type Case Reports ; Journal Article
    ISSN 2078-2101
    ISSN 2078-2101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Successful treatment of acute renal failure secondary to complicated infective endocarditis by peritoneal dialysis: a case report.

    Al-Osail, Aisha M / Al-Zahrani, Ibrahim M / Al-Abdulwahab, Abdullah A / Alhajri, Sarah M / Al-Osail, Emad M / Al-Hwiesh, Abdullah K / Al-Muhanna, Fahad A

    BMC research notes

    2017  Volume 10, Issue 1, Page(s) 463

    Abstract: Background: Infective endocarditis is one of the most common infections among intravenous drug addicts. Its complications can affect many systems, and these can include acute renal failure. There is a scarcity of cases in the literature related to acute ...

    Abstract Background: Infective endocarditis is one of the most common infections among intravenous drug addicts. Its complications can affect many systems, and these can include acute renal failure. There is a scarcity of cases in the literature related to acute renal failure secondary to infective endocarditis treated with peritoneal dialysis. In this paper, the case of a 48-year-old Saudi male is reported, who presented with features suggestive of infective endocarditis and who developed acute kidney injury that was treated successfully with high tidal volume automated peritoneal dialysis. To our knowledge, this is the second report of such an association in the literature.
    Case presentation: A 48-year-old Saudi gentleman diagnosed to have a glucose-6-phosphate dehydrogenase deficiency and hepatitis C infection for the last 9 years, presented to the emergency department with a history of fever of 2 days' duration. On examination: his temperature = 41 °C, there was clubbing of the fingers bilaterally and a pansystolic murmur in the left parasternal area. The results of the blood cultures and echocardiogram were supportive of the diagnosis of infective endocarditis, and the patient subsequently developed acute kidney injury, and his creatinine reached 5.2 mg/dl, a level for which dialysis is essential for the patient to survive.
    Conclusion: High tidal volume automated peritoneal dialysis is highly effective as a renal replacement therapy in acute renal failure secondary to infective endocarditis if no contraindication is present.
    Language English
    Publishing date 2017-09-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-017-2773-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Is Cronbach's alpha sufficient for assessing the reliability of the OSCE for an internal medicine course?

    Al-Osail, Aisha M / Al-Sheikh, Mona H / Al-Osail, Emad M / Al-Ghamdi, Mohannad A / Al-Hawas, Abdulaziz M / Al-Bahussain, Abdullah S / Al-Dajani, Ahmed A

    BMC research notes

    2015  Volume 8, Page(s) 582

    Abstract: Background: The number of medical students accepted into medical programs is increasing, which has made the traditional long/short case style of examination difficult to conduct. At Dammam University, the program is shifting to the use of the Objective ... ...

    Abstract Background: The number of medical students accepted into medical programs is increasing, which has made the traditional long/short case style of examination difficult to conduct. At Dammam University, the program is shifting to the use of the Objective Structural Clinical Examination (OSCE), which may solve some of these difficulties, including issues with reliability, validity index and exam duration.
    Results: A pilot study was conducted over one semester. A total of 207 examinees in three groups took the OSCE and written exams. The OSCE consisted of 18 clinical stations and required 3-4.3 h/day. The written exam contained 80 multiple-choice questions. The Cronbach's alpha for each group was 0.7, 0.8, and 0.9. Correlations for all stations ranged from 0.7 to 0.8, which indicated good stability and internal consistency with minor differences in the progression of the indexes. The reliability of the written exam was 0.79, and the validity of the OSCE was 0.63, as assessed using Pearson's correlation.
    Conclusion: No single reliability index can be considered a perfect assessment tool to solve this issue. Thus, at least two to three indexes should be used to ensure the reliability of the OSCE.
    MeSH term(s) Curriculum ; Educational Measurement ; Factor Analysis, Statistical ; Female ; Humans ; Internal Medicine ; Male ; Reproducibility of Results ; Statistics as Topic
    Language English
    Publishing date 2015-10-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-015-1533-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Successful treatment of acute renal failure secondary to complicated infective endocarditis by peritoneal dialysis

    Aisha M. Al-Osail / Ibrahim M. Al-Zahrani / Abdullah A. Al-Abdulwahab / Sarah M. Alhajri / Emad M. Al-Osail / Abdullah K. Al-Hwiesh / Fahad A. Al-Muhanna

    BMC Research Notes, Vol 10, Iss 1, Pp 1-

    a case report

    2017  Volume 5

    Abstract: Abstract Background Infective endocarditis is one of the most common infections among intravenous drug addicts. Its complications can affect many systems, and these can include acute renal failure. There is a scarcity of cases in the literature related ... ...

    Abstract Abstract Background Infective endocarditis is one of the most common infections among intravenous drug addicts. Its complications can affect many systems, and these can include acute renal failure. There is a scarcity of cases in the literature related to acute renal failure secondary to infective endocarditis treated with peritoneal dialysis. In this paper, the case of a 48-year-old Saudi male is reported, who presented with features suggestive of infective endocarditis and who developed acute kidney injury that was treated successfully with high tidal volume automated peritoneal dialysis. To our knowledge, this is the second report of such an association in the literature. Case presentation A 48-year-old Saudi gentleman diagnosed to have a glucose-6-phosphate dehydrogenase deficiency and hepatitis C infection for the last 9 years, presented to the emergency department with a history of fever of 2 days’ duration. On examination: his temperature = 41 °C, there was clubbing of the fingers bilaterally and a pansystolic murmur in the left parasternal area. The results of the blood cultures and echocardiogram were supportive of the diagnosis of infective endocarditis, and the patient subsequently developed acute kidney injury, and his creatinine reached 5.2 mg/dl, a level for which dialysis is essential for the patient to survive. Conclusion High tidal volume automated peritoneal dialysis is highly effective as a renal replacement therapy in acute renal failure secondary to infective endocarditis if no contraindication is present.
    Keywords Infective endocarditis ; Staphylococcus aureus ; Automated peritoneal dialysis ; Acute kidney injury ; Medicine ; R ; Biology (General) ; QH301-705.5 ; Science (General) ; Q1-390
    Subject code 616
    Language English
    Publishing date 2017-09-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Colonoscopy in automated peritoneal dialysis patients: value of prophylactic antibiotics: a prospective study on a single antibiotic.

    Al-Hwiesh, Abdullah K / Abdul-Rahman, Ibrahiem S / Hussameldeen, Mohammad A / Al-Audah, Nadia / Abdelrahman, Abdalla / Moaigel, Hala M / El-Salamony, Tamer / Noor, Abdul-Salam / Al-Osail, Aisha / Al-Sayel, Dalal / Al-Dossari, Nourah

    The International journal of artificial organs

    2017  Volume 40, Issue 10, Page(s) 550–557

    Abstract: Objective: To evaluate the need for prophylactic antibiotics in automated peritoneal dialysis (APD) patients undergoing flexible colonoscopy.: Patients and methods: A total of 93 patients on automated peritoneal dialysis (APD) undergoing diagnostic ... ...

    Abstract Objective: To evaluate the need for prophylactic antibiotics in automated peritoneal dialysis (APD) patients undergoing flexible colonoscopy.
    Patients and methods: A total of 93 patients on automated peritoneal dialysis (APD) undergoing diagnostic colonoscopy were enrolled in a prospective, randomized study. Patients were randomized into 2 age- and sex-matched groups; group A (46 patients) with intraperitoneal (IP) ceftazidime prior to colonoscopy and group B (47 patients) without prophylactic antibiotics. The relations between peritonitis and different parameters were analyzed.
    Results: Of all colonoscopies, 60.2% showed normal findings, 17.2% with colonic polyps at different sites, 12.9% with angiodysplastic-like lesions, 5.4% with colonic ulcer(s), 3.2% with diverticulae without diverticulitis and 1.1% had transverse colon stricture. Post-colonoscopy peritonitis was documented in 3 (6.5%) and 4 (8.5%) patients in groups A and B, respectively (p = 0.2742); the causative organisms were mainly gram negative bacteria. Polypectomy was not associated with increased peritonitis episodes. By multiple logistic regression analysis, diabetes mellitus was the only independent variable that entered into the best predictive equation over the development of post-colonoscopy peritonitis but not antibiotic use.
    Conclusions: The relation between prophylactic antibiotic use prior to colonoscopy in APD patients and the risk of peritonitis was lacking. Only diabetes mellitus appears to be of significance. Polypectomy did not increase peritonitis episodes.
    Language English
    Publishing date 2017-10-13
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 80456-3
    ISSN 1724-6040 ; 0391-3988
    ISSN (online) 1724-6040
    ISSN 0391-3988
    DOI 10.5301/ijao.5000612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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