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Article: Intoxication-Related Deaths in a Poisoning Center in Isfahan: Demographic and Other-Related Factors.

Dorooshi, Gholamali / Meamar, Rokhsareh / Kalantar, Kamran / Amini, Zahra

2022 Volume 11, Page(s) 82

Abstract: Background: The aim of this study was to investigate the frequency of poisoning mortality in the 5-year period of 2014-2019 in Isfahan Khorshid Hospital, Iran.: Materials and methods: This study is a cross-sectional descriptive analytical study, ... ...

Abstract	Background: The aim of this study was to investigate the frequency of poisoning mortality in the 5-year period of 2014-2019 in Isfahan Khorshid Hospital, Iran. Materials and methods: This study is a cross-sectional descriptive analytical study, which was performed in 2020. The demographic and clinical data about the patients were extracted from the patients' files and were then analyzed. Results: The number of deaths due to poisoning in the study period was 264, and the mean age of the deceased was 42.33 ± 20.097. One hundred and ninety-three (73.1%) patients were male. The frequency of deaths in the poisoning ward was 0.84%. The causes of death were accidental overdose (73, 26.9%), suicide (155, 63.2%), accidental use (18, 7.3%), and homicide in one patient. The mean age, time between exposure of toxin until death and history of addiction, substance use, and suicide in men patients was significantly higher than women ( Conclusion: In this study, we showed that the death rate due to poisoning in our center was lower than other centers. The highest number of poisoning was in men as well as married patients. It is also recommended that more serious educational and preventive strategies should be used in this regard.
Language	English
Publishing date	2022-09-27
Publishing country	India
Document type	Journal Article
ZDB-ID	2672524-1
ISSN	2277-9175
ISSN	2277-9175
DOI	10.4103/abr.abr_61_21
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Comparing Sequential Organ Failure Assessment Score, Acute Physiology and Chronic Health Evaluation II, Modified Acute Physiology and Chronic Health Evaluation II, Simplified Acute Physiology Score II and Poisoning Severity Score for Outcome Prediction of Pesticide Poisoned Patients Admitted to the Intensive Care Unit.

Dorooshi, Gholamali / Samsamshariat, Shiva / Gheshlaghi, Farzad / Zoofaghari, Shafeajafar / Hasanzadeh, Akbar / Abbasi, Saeed / Eizadi-Mood, Nastaran

Journal of research in pharmacy practice

2024 Volume 12, Issue 2, Page(s) 49–57

Abstract: Objective: This study aimed to assess the severity of poisoning, various scoring systems, including Sequential Organ Failure Assessment (SOFA) score, acute physiology and chronic health evaluation II (APACHE II), Simplified Acute Physiology Score (SAPS ... ...

Abstract	Objective: This study aimed to assess the severity of poisoning, various scoring systems, including Sequential Organ Failure Assessment (SOFA) score, acute physiology and chronic health evaluation II (APACHE II), Simplified Acute Physiology Score (SAPS II), Modified APACHE II, and poisoning severity score (PSS) were used. In this study, we compared the predictive value of these scoring systems on the outcome of pesticide-poisoned patients. Methods: This is a cross-sectional study of pesticide-poisoned patients (140 patients) who were admitted to the intensive care unit (ICU) of Khorshid Hospital, Isfahan, Iran, between January 2015 and 2019. The area under the receiver operating characteristic (AUC) curve and the predictive value of scoring systems were compared. Findings: Poisoning was higher in the male population (72.8%). The causes of poisoning were paraquat, (38.6%), aluminum phosphide, (32.1%), and organophosphate, (29.3%). The mean age of the patients was 33.9 years. Most patients (79.3%) attempted suicide. The mortality rate was 46.43%. The mean of "SOFA score," "APACHE II," "SAPS II," "Modified APACHE II," and "PSS" was 5.9; 15.7; 30.02; 15.8; and 1.9, respectively. There was a significant difference in the mean of all scoring systems for outcome prediction. Among all scoring systems, the SAPS II score with the cutoff point (16.5) had the best criteria for outcome prediction (AUC (0.831 ± 0.037), sensitivity (83.1%, 95% confidence interval [CI]: [71.7-91.2]), specificity (75.7%, 95% CI: [64.3-84.9]), positive predictive values (75.0%, 95% CI: [66.4-82.0]), negative predictive values (83.6%, 95% CI: [74.5-89.9]). Conclusion: The SAPS II scoring system may be a suitable indicator for outcome predictions in pesticide-poisoned patients in the ICU.
Language	English
Publishing date	2024-01-31
Publishing country	India
Document type	Journal Article
ZDB-ID	2734861-1
ISSN	2279-042X ; 2319-9644
ISSN (online)	2279-042X
ISSN	2319-9644
DOI	10.4103/jrpp.jrpp_43_23
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Article: A Clinical-Epidemiological Study on Beta-Blocker Poisonings Based on the Type of Drug Overdose.

Eizadi-Mood, Nastaran / Adib, Mahtab / Otroshi, Arman / Dorooshi, Gholamali / Meamar, Rokhsareh

Journal of toxicology

2023 Volume 2023, Page(s) 1064955

Abstract: Background: Beta-blockers carry a high risk of potentially causing fatal poisoning if overdosed. We aimed to assess the clinical and epidemiological characteristics of patients with beta-blocker poisoning.: Methods: Patients were categorized based on ...

Abstract	Background: Beta-blockers carry a high risk of potentially causing fatal poisoning if overdosed. We aimed to assess the clinical and epidemiological characteristics of patients with beta-blocker poisoning. Methods: Patients were categorized based on the type of drug poisoning into propranolol, other beta-blockers, and the combination of beta-blocker groups, respectively. Demographic data, drug toxicity, and clinical, laboratory, and treatment information of different groups were compared. Results: During the study period, 5086 poisoned patients were hospitalized, of whom 255 (5.1%) had beta-blocker poisoning. Most patients were women (80.8%), married (50.6%), with a history of psychiatric disorders (36.5%), previous suicide attempts (34.6%), and intentional type of exposure (95.3%). The mean ± SD age of the patients was 28.94 ± 11.08 years. Propranolol toxicity was the most common among different beta-blockers (84.4%). There was a significant difference in age, occupation, education level, and history of psychiatric diseases with respect to the type of beta-blocker poisoning ( Conclusion: Beta-blocker poisoning is not common in our poisoning referral center. Propranolol toxicity was most common among different beta-blockers. Although symptoms are not different among defined beta-blocker groups, more severe symptoms are observed in the combination of the beta-blocker group. Only one patient had a fatal outcome in the toxicity with the combination of the beta-blocker group. Therefore, poisoning circumstances have to investigate thoroughly to screen coexposure with combined drugs.
Language	English
Publishing date	2023-02-24
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2495098-1
ISSN	1687-8205 ; 1687-8191
ISSN (online)	1687-8205
ISSN	1687-8191
DOI	10.1155/2023/1064955
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Article: Catfish stings: A report of two cases.

Dorooshi, Gholamali

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

2013 Volume 17, Issue 6, Page(s) 578–581

Abstract: Venomous catfish stings are a common environment hazard worldwide. Although these stings are often innocuous, significant morbidity may result from stings, including severe pain, retained foreign bodies, infection, respiratory compromise, arterial ... ...

Abstract	Venomous catfish stings are a common environment hazard worldwide. Although these stings are often innocuous, significant morbidity may result from stings, including severe pain, retained foreign bodies, infection, respiratory compromise, arterial hypotension, and cardiac dysrhythmias. Treatment included hot water immersion, analgesia, wound exploration, and prophylactic antibiotics. In this article, two cases of stings by catfish referred to the poison center of Noor Hospital, Isfahan University of Medical Sciences and their treatments have been reported.
Language	English
Publishing date	2013-04-19
Publishing country	India
Document type	Case Reports
ZDB-ID	2513029-8
ISSN	1735-7136 ; 1735-1995
ISSN (online)	1735-7136
ISSN	1735-1995
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Article: Plasmapheresis for the management of acute cyanide poisoning: A case report and review of literature.

Namakizadeh Esfahani, Navid / Zoofaghari, Shafeajafar / Akhavan Sigari, Amirhossein / Dorooshi, Gholamali

Clinical case reports

2021 Volume 9, Issue 6, Page(s) e04228

Abstract: In case of mild to moderate cyanide poisoning, especially when standard antidote kits are not readily available, plasmapheresis can be utilized as an alternative option alongside supportive measures. ...

Abstract	In case of mild to moderate cyanide poisoning, especially when standard antidote kits are not readily available, plasmapheresis can be utilized as an alternative option alongside supportive measures.
Language	English
Publishing date	2021-06-24
Publishing country	England
Document type	Case Reports
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.4228
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Article: Myocardial infarction without coronary artery occlusion following mental stress.

Zoofaghari, Shafeajafar / Nikaen, Fariborz / Bahramsari, Shahrzad / Hashemzadeh, Mozhdeh / Dorooshi, Gholamali

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

2021 Volume 26, Page(s) 12

Abstract: Myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) is syndrome with clinical evidence of acute MI (AMI) with normal coronary arteries. This study reports the case of a 23-year-old single woman referring to the hospital with ... ...

Abstract	Myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) is syndrome with clinical evidence of acute MI (AMI) with normal coronary arteries. This study reports the case of a 23-year-old single woman referring to the hospital with clinical manifestations of MI, with electrocardiography findings of slow ventricular tachycardia or accelerated idioventricular rhythm and atrioventricular dissociation, and high troponin levels, which was admitted with the diagnosis of MINOCA due to mental stress (grief) and was discharged after 4 days of monitoring and following stabilization of conditions and absence of symptoms. Other causes of MINOCA ruled out through imaging studies. Mental stress can lead to MINOCA.
Language	English
Publishing date	2021-02-27
Publishing country	India
Document type	Case Reports
ZDB-ID	2513029-8
ISSN	1735-7136 ; 1735-1995
ISSN (online)	1735-7136
ISSN	1735-1995
DOI	10.4103/jrms.JRMS_128_20
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Article: An Unusual Acute Cyanide Intoxication.

Dorooshi, Gholamali / Dorostkar, Amin / Rahimi, Alireza / Zoofaghari, Shafeajafar

Advanced biomedical research

2020 Volume 9, Page(s) 42

Abstract: Suicide with cyanides is relatively rare but highly lethal. The lethal oral dose of cyanide salts is 200 mg, and concentrations >3 mg/L may be potentially lethal. The symptoms of poisoning are predominating in the central nervous system and ... ...

Abstract	Suicide with cyanides is relatively rare but highly lethal. The lethal oral dose of cyanide salts is 200 mg, and concentrations >3 mg/L may be potentially lethal. The symptoms of poisoning are predominating in the central nervous system and cardiovascular system. We report the case of a 43-year-old goldsmith man who presented with self-poisoning by cyanide salt ingestion. Patient's symptoms included confusion, cardiac arrhythmias, hyperkalemia, leukocytosis, metabolic acidosis with high anion gap, hypotension, and then hypertension. The cause of the patients poisoning was not initially diagnosed. Intensive supportive treatment was performed. The patient died on the 3
Language	English
Publishing date	2020-08-28
Publishing country	India
Document type	Case Reports
ZDB-ID	2672524-1
ISSN	2277-9175
ISSN	2277-9175
DOI	10.4103/abr.abr_128_20
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Article: Serotonin Toxicity Following Suicide with Citalopram and Lamotrigine: A Rare Case Report and Literature Review.

Dorooshi, Gholamali / Zoofaghari, Shafeajafar / Meamar, Rokhsareh

Journal of research in pharmacy practice

2020 Volume 9, Issue 3, Page(s) 158–160

Abstract: Serotonin toxicity is a common but often unrecognized toxicological condition. In most cases, a combination of two or more serotonergic drugs can cause serotonin syndrome. We describe a case of serotonin toxicity in a 17-year-old woman, secondary to ... ...

Abstract	Serotonin toxicity is a common but often unrecognized toxicological condition. In most cases, a combination of two or more serotonergic drugs can cause serotonin syndrome. We describe a case of serotonin toxicity in a 17-year-old woman, secondary to suicidal ingestion of 1000 mg lamotrigine and 400 mg citalopram, which has been rarely reported. Our patient had a medical history of depression and was treated with lamotrigine and citalopram. She was brought to the emergency room with nausea, diaphoresis, agitation, shivering, tremor, vertigo, ataxia, mydriasis, nystagmus, hyperreflexia, myoclonus, tachycardia, tachypnea, and mild fever. The symptoms and signs were resolved within 3 days following hydration, sedation, and cyproheptadine. Minor cardiovascular symptoms are probably due to the less toxic dose of citalopram. Lamotrigine, especially in combination with other serotonergic drugs, should be considered a cause of serotonin toxicity.
Language	English
Publishing date	2020-10-08
Publishing country	India
Document type	Case Reports
ZDB-ID	2734861-1
ISSN	2279-042X ; 2319-9644
ISSN (online)	2279-042X
ISSN	2319-9644
DOI	10.4103/jrpp.JRPP_19_105
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Article: Investigating the Outcomes of Aluminum Phosphide Poisoning in Khorshid Referral Hospital, Isfahan, Iran: A Retrospective Study.

Dorooshi, Gholamali / Mirzae, Meysam / Fard, Negah Tavakoli / Zoofaghari, Shafeajafar / Mood, Nastaran Eizadi

Journal of research in pharmacy practice

2022 Volume 10, Issue 4, Page(s) 166–173

Abstract: Objective: Aluminum phosphide (ALP) (rice-tablet) is a common cause of adult poisoning in Iran, including Isfahan. So far, no effective treatment has been identified for this poisoning. We aimed to investigate the outcome of ALP poisoned patients ... ...

Abstract	Objective: Aluminum phosphide (ALP) (rice-tablet) is a common cause of adult poisoning in Iran, including Isfahan. So far, no effective treatment has been identified for this poisoning. We aimed to investigate the outcome of ALP poisoned patients admitted to the clinical toxicology ward of Khorshid Hospital in Isfahan from 2017 to 2019. Methods: This chart-review study was performed on the population of ALP poisoned patients admitted to the clinical toxicology ward of Khorshid University Hospital from 2017 to 2019 treated with the hospital's new treatment protocol, using the complete enumeration approach. The outcomes were determined by reviewing and abstracting medical charts of ALP poisoned patients from the hospital archive. Findings: The most common complaints at admission were depressed consciousness (41.9%) and vomiting (32.2%). There was no significant change in blood sugar, pH, base excess (BE), and venous blood bicarbonate throughout their hospitalization ( Conclusion: The mortality rate of ALP poisoned patients was reasonably high and can be attributed to the poor efficacy of the new treatment protocol or the long time it takes for patients to reach the hospital and start receiving treatments.
Language	English
Publishing date	2022-05-25
Publishing country	India
Document type	Journal Article
ZDB-ID	2734861-1
ISSN	2279-042X ; 2319-9644
ISSN (online)	2279-042X
ISSN	2319-9644
DOI	10.4103/jrpp.jrpp_88_21
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Article: Comparison of Clinical Manifestations of Patients Poisoned with Tricyclic Antidepressants Alone or with Benzodiazepine Intoxication According to the Dose of Benzodiazepines.

Dorooshi, Gholamali / Kermani, Rasool / Sabzghabaee, Ali Mohammad / Mansourian, Marjan / Eizadi-Mood, Nastaran

Journal of research in pharmacy practice

2022 Volume 11, Issue 2, Page(s) 59–63

Abstract: Objective: Tricyclic antidepressants poisoning (TCA) is associated with cardiovascular complications, electrocardiographic abnormalities, and central nervous system toxicity. This study aimed to compare the clinical manifestations of poisoned patients ... ...

Abstract	Objective: Tricyclic antidepressants poisoning (TCA) is associated with cardiovascular complications, electrocardiographic abnormalities, and central nervous system toxicity. This study aimed to compare the clinical manifestations of poisoned patients with tricyclic antidepressants alone or with benzodiazepine (BZD) intoxication according to the dose of BZDs. Methods: In this case-control study, 120 patients with TCA poisoning were divided into four groups: the first group of TCA poisoning alone, the second group of TCA and BZD poisoning of <7.75 mg, the third group of TCA and B poisoning of 7.75 to 80 mg, and the fourth group of more than 80 mg of TCA and BZD poisoning. Patients' demographic, clinical, and cardiac information was extracted from their records at admission and 6 h after admission. Findings: Cardiac complications 6 h after referral and total cardiac complications between TCA and TCA low-dose BZD groups were significantly reduced in the low-dose BZD poisoning group. Comparison of TCA and TCA groups with a moderate dose of BZD showed a significant reduction in time six and total cardiac complications. However, due to the significant difference in TCA values between the two groups, the results are not significant. Comparing the two groups of TCA and TCA with a high dose of BZD, both 6-hour cardiac complications and total cardiac complications in the high-dose BZD group, it was significantly reduced. However, the loss of consciousness was also considerably greater in the high-dose BZD group than in the TCA group. Conclusion: Concomitant BZDs with TCA can reduce cardiovascular complications from TCA poisoning. However, with high doses of BZDs, there is a greater loss of consciousness.
Language	English
Publishing date	2022-12-14
Publishing country	India
Document type	Journal Article
ZDB-ID	2734861-1
ISSN	2279-042X ; 2319-9644
ISSN (online)	2279-042X
ISSN	2319-9644
DOI	10.4103/jrpp.jrpp_43_21
Database	MEDical Literature Analysis and Retrieval System OnLINE

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