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  1. Book: Cardiovascular medicine and surgery

    Mukherjee, Debabrata / Lange, Richard A.

    2022  

    Author's details Senior editors Debabrata Mukherjee, Richard A Lange
    Keywords Cardiovascular Diseases / diagnosis ; Cardiovascular Diseases / therapy ; Cardiovascular Surgical Procedures / methods ; Diagnostic Techniques, Cardiovascular
    Language English
    Size xl, 1259 Seiten, Illustrationen
    Edition First edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index ; Zugang zu Online-Ausgabe über Code
    HBZ-ID HT021283162
    ISBN 978-1-975148-21-8 ; 1-975148-21-5
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Types and other historical specimens of Allan and Richard Cunningham's taxa of Epilobium and Fuchsia (Onagraceae) from New Zealand in the Turczaninow Herbarium at the National Herbarium of Ukraine (KW)

    Mosyakin S.L. / de Lange P.J. / Antonenko S.I. / Klimovych N.B.

    Ukrai̤nskyĭ botanychnyĭ zhurnal. 2020 Aug., v. 77, no. 4

    2020  

    Abstract: ... of Allan and Richard Cunningham's taxa of Epilobium and Fuchsia (Onagraceae) from New Zealand recently ... by Richard Cunningham in 1833–1834, represent the following taxa (as outlined by A. Cunningham): Epilobium ... collected in New Zealand in the first half of the 19th century by Allan Cunningham, Richard Cunningham, J ...

    Abstract Thirteen historical specimens (including original material, mainly syntypes and isolectotypes) of Allan and Richard Cunningham's taxa of Epilobium and Fuchsia (Onagraceae) from New Zealand recently discovered in the Turczaninow Herbarium (KW-TURCZ) at the National Herbarium of Ukraine (KW) are discussed in comparison with digital images of and data on other relevant specimens from several other herbaria, such as K, BM, WELT, etc. These specimens, collected in New Zealand by Allan Cunningham in 1826 and 1838 and by Richard Cunningham in 1833–1834, represent the following taxa (as outlined by A. Cunningham): Epilobium alsinoides, E. atriplicifolium, E. confertum, E. hirtigerum, E. nerterioides, E. nummulariifolium, E. pedunculare, E. thymifolium, E. virgatum (A.Cunn., non Lam.), and Fuchsia procumbens. It is demonstrated that type designations for some names in Epilobium mentioned above remain problematic; some names appear to be not yet typified effectively. These problems are caused by several factors, such as misplaced original labels or specimens, errors or misinterpretations in curatorial or copied labels, a complicated numbering system applied by A. Cunningham, etc. Critical re-assessment of all available original and other associated specimens of the mentioned names in Epilobium, especially those in K, is needed. Before such re-assessment, we refrain from any nomenclatural actions affecting type designations. The recent discovery in KW-TURCZ of important historical specimens (not only Onagraceae but also many other plant families) collected in New Zealand in the first half of the 19th century by Allan Cunningham, Richard Cunningham, J. Everard Home and some other early explorers is not only interesting from a historical viewpoint but also important for taxonomy, especially for proper application of names validated by A. Cunningham.
    Keywords Epilobium ; Fuchsia ; herbaria ; isolectotypes ; New Zealand ; Ukraine
    Language English
    Dates of publication 2020-08
    Size p. 249-269.
    Publishing place M.G.Kholodny Institute of Botany
    Document type Article
    ZDB-ID 2998517-1
    ISSN 2415-8860 ; 0372-4123
    ISSN (online) 2415-8860
    ISSN 0372-4123
    DOI 10.15407/ukrbotj77.04.249
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Platelet-rich plasma and ovarian quiescence: a bovine

    Lange-Consiglio, Anna / Gaspari, Giulia / Riccaboni, Pietro / Canesi, Simone / Bosi, Giampaolo / Vigo, Daniele / Cremonesi, Fausto

    Reproduction, fertility, and development

    2023  Volume 35, Issue 7, Page(s) 433–444

    Abstract: ... of platelet rich plasma (PRP) on bovine in vitro models to understand its effect on granulosa cells.: Methods ...

    Abstract Context: Ovarian quiescence can be due to hormonal deficiency usually caused by apoptosis of granulosa cells responsible for oestrogen synthesis.
    Aim: This study evaluated the regenerative effect of platelet rich plasma (PRP) on bovine in vitro models to understand its effect on granulosa cells.
    Methods: Quiescent and healthy ovarian sections were cultured in the presence/absence of PRP for 72h and, at different times (0, 24, 48 and 72h), hematoxylin-eosin and immunohistochemical detection of Ki-67 were performed. Additionally, granulosa cells collected from healthy bovine ovaries were stressed with 100ng/mL of lipopolysaccharide (LPS) in presence/absence of PRP and evaluated at 0, 4, 8 and 24h for apoptosis by acridine orange and propidium iodide staining. Enzyme-linked immunosorbent assay tests were performed to evaluate oestrogen (E2) and anti-Müllerian hormone (AMH) concentrations on cultures of ovarian slices and granulosa cells.
    Key results: In slides of quiescent ovaries treated with PRP, a marked and widespread positivity to Ki-67 was expressed by 40-60% of the follicular wall cells at 48h of culture. Levels of E2 and AMH were significantly higher compared to untreated quiescent samples reaching the levels of healthy control samples. PRP counteracted the LPS effect and apoptosis (at 24h, there were 93.44±3.51% live cells with LPS+PRP compared to 37±1.32% with LPS) and significantly increased concentrations of E2 and AMH.
    Conclusions: PRP can stimulate granulosa cell proliferation and counteract inflammatory processes in vitro .
    Implications: This treatment could improve the reproductive ability of quiescent females.
    MeSH term(s) Female ; Animals ; Cattle ; Ovary ; Ki-67 Antigen ; Lipopolysaccharides/pharmacology ; Estrogens/pharmacology ; Anti-Mullerian Hormone ; Platelet-Rich Plasma ; Regeneration
    Chemical Substances Ki-67 Antigen ; Lipopolysaccharides ; Estrogens ; Anti-Mullerian Hormone (80497-65-0)
    Language English
    Publishing date 2023-04-10
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1019913-5
    ISSN 1448-5990 ; 1031-3613
    ISSN (online) 1448-5990
    ISSN 1031-3613
    DOI 10.1071/RD23017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Synergistic Effects of Surface Coating and Bulk Doping in Ni-Rich Lithium Nickel Cobalt Manganese Oxide Cathode Materials for High-Energy Lithium-Ion Batteries.

    Reissig, Friederike / Lange, Martin A / Haneke, Lukas / Placke, Tobias / Zeier, Wolfgang G / Winter, Martin / Schmuch, Richard / Gomez-Martin, Aurora

    ChemSusChem

    2022  Volume 15, Issue 4, Page(s) e202200078

    Abstract: Invited for this month's cover is a combined work of the Helmholtz Institute Münster together with the MEET Battery Research Center and the Universities of Münster and Mainz. The cover shows multiple treatment choices for the modification of cathode ... ...

    Abstract Invited for this month's cover is a combined work of the Helmholtz Institute Münster together with the MEET Battery Research Center and the Universities of Münster and Mainz. The cover shows multiple treatment choices for the modification of cathode active materials for lithium-ion batteries. Similar to a car wash program, the treatment will typically result in an improvement of the status quo. However, the best treatment procedure will only become clear if all modification pathways are explored. The Research Article itself is available at 10.1002/cssc.202102220.
    Language English
    Publishing date 2022-01-31
    Publishing country Germany
    Document type Journal Article
    ISSN 1864-564X
    ISSN (online) 1864-564X
    DOI 10.1002/cssc.202200078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Akademische Gedenkfeier für Prof. Dr. Richard Lange

    Lange, Richard

    1906 - 1995 ; am 7. November 1996

    1996  

    Title variant Richard Lange zum Gedächtnis
    Institution Verein zur Förderung der Rechtswissenschaft
    Author's details hrsg. vom Verein zur Förderung der Rechtswissenschaft
    Language German
    Size 30 S., 1 Ill.
    Publisher Verein zur Förderung der Rechtswissenschaft
    Publishing place Köln
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  6. Article ; Online: Synergistic Effects of Surface Coating and Bulk Doping in Ni-Rich Lithium Nickel Cobalt Manganese Oxide Cathode Materials for High-Energy Lithium Ion Batteries.

    Reissig, Friederike / Lange, Martin Alexander / Haneke, Lukas / Placke, Tobias / Zeier, Wolfgang G / Winter, Martin / Schmuch, Richard / Gomez-Martin, Aurora

    ChemSusChem

    2021  Volume 15, Issue 4, Page(s) e202102220

    Abstract: Ni-rich layered oxide cathodes are promising candidates to satisfy the increasing energy demand ...

    Abstract Ni-rich layered oxide cathodes are promising candidates to satisfy the increasing energy demand of lithium-ion batteries for automotive applications. Thermal and cycling stability issues originating from increasing Ni contents are addressed by mitigation strategies such as elemental bulk substitution ("doping") and surface coating. Although both approaches separately benefit the cycling stability, there are only few reports investigating the combination of two of such approaches. Herein, the combination of Zr as common dopant in commercial materials with effective Li
    Language English
    Publishing date 2021-12-02
    Publishing country Germany
    Document type Journal Article
    ISSN 1864-564X
    ISSN (online) 1864-564X
    DOI 10.1002/cssc.202102220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Rich and sparse figurative information in children's memory for colorful places.

    Lange-Küttner, Christiane / Collins, Chenelle L / Ahmed, Rahima K / Fisher, Lauren E

    Developmental psychology

    2022  Volume 59, Issue 2, Page(s) 256–271

    Abstract: The relation between perceptual and conceptual knowledge is a longstanding research question in developmental psychology. Here we tested children's dependence on figurative information with a reaction time/accuracy task. A sample of 151 children from 5 ... ...

    Abstract The relation between perceptual and conceptual knowledge is a longstanding research question in developmental psychology. Here we tested children's dependence on figurative information with a reaction time/accuracy task. A sample of 151 children from 5 to 10 years were assessed from two multicultural and multiracial schools in the London (UK) boroughs City of London and Harrow. A quarter of children in both schools were eligible for free school meals (national average 18.5%). The same 3 × 3 grid with nine individually colored places and a uniform black star as placeholder was tested in three different retrieval conditions: (a) same array as during presentation, (b) one place at a time with placeholder, and (c) one place at a time without placeholder. In a (d) control condition, individual shapes were of the same color as the colorful places. Bayes Factor analyses showed a more unified response toward figurative placeholders in 5- to 6-year-olds. Independently of age, colorful places without a placeholder were hardest to remember. Places were better remembered when a placeholder was added and still better when the spatial context of the entire array was available. Yet unique shapes with distinctive contours and colors as placeholders optimized place memory the most. While place memory accuracy increased with age, reaction times did not become faster. Instead, latencies were longer, the more visual information was available in the retrieval array. A larger perceptual effect was caused by the dynamic where-delay interference task, the sparser the amount of visual information in the retrieval array. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
    MeSH term(s) Humans ; Child ; Bayes Theorem ; Mental Recall ; Reaction Time/physiology ; Form Perception ; London
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2066223-3
    ISSN 1939-0599 ; 0012-1649
    ISSN (online) 1939-0599
    ISSN 0012-1649
    DOI 10.1037/dev0001483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: REAFFIRMING THE CORE VALUES OF ACADEMIC CARDIOLOGY.

    Cigarroa, Joaquin E / Lange, Richard A

    Transactions of the American Clinical and Climatological Association

    2023  Volume 133, Page(s) 93–98

    Abstract: Academic medical centers are rapidly evolving into academic health systems with expanding clinical activity. These changes coupled with financial pressures due to decreased clinical reimbursements and failure of the NHLBI budget to keep pace with ... ...

    Abstract Academic medical centers are rapidly evolving into academic health systems with expanding clinical activity. These changes coupled with financial pressures due to decreased clinical reimbursements and failure of the NHLBI budget to keep pace with inflation are challenging the ability to succeed in all our missions. New governance structures and financial models may be necessary to success in our research and educational missions.
    MeSH term(s) Humans ; Cardiology ; Academic Medical Centers
    Language English
    Publishing date 2023-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603823-2
    ISSN 0065-7778
    ISSN 0065-7778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Recent updates on therapeutic targeting of lipoprotein(a) with RNA interference.

    Sekhar, Aravind / Kuttan, Ashani / Lange, Richard A

    Current opinion in cardiology

    2024  

    Abstract: Purpose: RNA interference (RNAi)-based therapies that target specific gene products have impacted clinical medicine with 16 FDA approved drugs. RNAi therapy focused on reducing plasma lipoprotein(a) [Lp(a)] levels are under evaluation.: Findings: ... ...

    Abstract Purpose: RNA interference (RNAi)-based therapies that target specific gene products have impacted clinical medicine with 16 FDA approved drugs. RNAi therapy focused on reducing plasma lipoprotein(a) [Lp(a)] levels are under evaluation.
    Findings: RNAi-based therapies have made significant progress over the past 2 decades and currently consist of antisense oligonucleotides (ASO) and small interfering RNA (siRNA). Chemical modification of the RNA backbone and conjugation of siRNA enables efficient gene silencing in hepatocytes allowing development of effective cholesterol lowering therapies. Multiple lines of evidence suggest a causative role for Lp(a) in atherosclerotic cardiovascular disease, and recent analyses indicate that Lp(a) is more atherogenic than low density lipoprotein- cholesterol (LDL-C). These findings have led to the 'Lp(a) hypothesis' that lowering Lp(a) may significantly improve cardiovascular outcomes. Four RNAi-based drugs have completed early phase clinical trials demonstrating >80% reduction in plasma Lp(a) levels. Phase 3 clinical trials examining clinical outcomes with these agents are currently underway.
    Summary: Currently, four RNAi-based drugs have been shown to be effective in significantly lowering plasma Lp(a) levels. Clinical outcome data from phase 3 trials will evaluate the Lp(a) hypothesis.
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645186-x
    ISSN 1531-7080 ; 0268-4705
    ISSN (online) 1531-7080
    ISSN 0268-4705
    DOI 10.1097/HCO.0000000000001144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Platelet-rich plasma and ovarian quiescence: a bovine <i>in vitro</i> model for regeneration of the ovary

    Lange-Consiglio, Anna / Gaspari, Giulia / Riccaboni, Pietro / Canesi, Simone / Bosi, Giampaolo / Vigo, Daniele / Cremonesi, Fausto

    Reproduction, Fertility and Development. 2023, v. 35, no. 7 p.433-444

    2023  

    Abstract: ... of platelet rich plasma (PRP) on bovine in vitro models to understand its effect on granulosa cells. Methods: Quiescent ...

    Abstract Context: Ovarian quiescence can be due to hormonal deficiency usually caused by apoptosis of granulosa cells responsible for oestrogen synthesis. Aim: This study evaluated the regenerative effect of platelet rich plasma (PRP) on bovine in vitro models to understand its effect on granulosa cells. Methods: Quiescent and healthy ovarian sections were cultured in the presence/absence of PRP for 72h and, at different times (0, 24, 48 and 72h), hematoxylin-eosin and immunohistochemical detection of Ki-67 were performed. Additionally, granulosa cells collected from healthy bovine ovaries were stressed with 100ng/mL of lipopolysaccharide (LPS) in presence/absence of PRP and evaluated at 0, 4, 8 and 24h for apoptosis by acridine orange and propidium iodide staining. Enzyme-linked immunosorbent assay tests were performed to evaluate oestrogen (E2) and anti-Müllerian hormone (AMH) concentrations on cultures of ovarian slices and granulosa cells. Key results: In slides of quiescent ovaries treated with PRP, a marked and widespread positivity to Ki-67 was expressed by 40–60% of the follicular wall cells at 48h of culture. Levels of E2 and AMH were significantly higher compared to untreated quiescent samples reaching the levels of healthy control samples. PRP counteracted the LPS effect and apoptosis (at 24h, there were 93.44±3.51% live cells with LPS+PRP compared to 37±1.32% with LPS) and significantly increased concentrations of E2 and AMH. Conclusions: PRP can stimulate granulosa cell proliferation and counteract inflammatory processes in vitro . Implications: This treatment could improve the reproductive ability of quiescent females.
    Keywords acridine orange ; apoptosis ; cattle ; cell proliferation ; enzyme-linked immunosorbent assay ; estrogens ; granulosa cells ; immunohistochemistry ; lipopolysaccharides ; models ; propidium ; reproductive performance ; bovine ovary ; hormones ; lipopolysaccharide ; ovarian quiescence ; platelet rich plasma ; regenerative medicine
    Language English
    Size p. 433-444.
    Publishing place CSIRO Publishing
    Document type Article ; Online
    ZDB-ID 1019913-5
    ISSN 1448-5990 ; 1031-3613
    ISSN (online) 1448-5990
    ISSN 1031-3613
    DOI 10.1071/RD23017
    Database NAL-Catalogue (AGRICOLA)

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