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  1. Article ; Online: The DELPHI Library: Improving Model Validation, Transparency and Dissemination Through a Centralised Library of Prediction Models.

    Williams, Ross D / den Otter, Sicco / Reps, Jenna M / Rijnbeek, Peter R

    Studies in health technology and informatics

    2023  Volume 302, Page(s) 139–140

    Abstract: The Deposit, Evaluate and Lookup Predictive Healthcare Information (DELPHI) library provides a centralised location for the depositing, exploring and analysing of patient-level prediction models that are compatible with data mapped to the observational ... ...

    Abstract The Deposit, Evaluate and Lookup Predictive Healthcare Information (DELPHI) library provides a centralised location for the depositing, exploring and analysing of patient-level prediction models that are compatible with data mapped to the observational medical outcomes partnership common data model.
    Language English
    Publishing date 2023-05-19
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI230085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Death by Copper Ammonium Complex-Containing Fungicide.

    Otter, Jenna / Cantrell, F Lee

    The American journal of forensic medicine and pathology

    2020  Volume 42, Issue 1, Page(s) 62–63

    Abstract: Abstract: There is a paucity of published reports of copper ammonium complex ingestion, as most published data describe overdoses of copper sulfate formulations. We report a case of suicide by ingestion of copper ammonium complex-containing fungicide ... ...

    Abstract Abstract: There is a paucity of published reports of copper ammonium complex ingestion, as most published data describe overdoses of copper sulfate formulations. We report a case of suicide by ingestion of copper ammonium complex-containing fungicide with an elevated postmortem copper level. A 77-year-old woman was found dead at home by her relative after ingesting a fungicide containing 8% copper ammonium complex solution. Turquoise emesis was found at the scene, and on autopsy, turquoise material was found throughout the gastrointestinal tract. Postmortem central blood copper level was 500 μg/dL. Cause of death was determined to be acute copper toxicity.
    MeSH term(s) Aged ; Ammonium Compounds/poisoning ; Copper/blood ; Copper/poisoning ; Depression/complications ; Female ; Fungicides, Industrial/poisoning ; Humans ; Suicidal Ideation ; Suicide, Completed
    Chemical Substances Ammonium Compounds ; Fungicides, Industrial ; Copper (789U1901C5)
    Language English
    Publishing date 2020-09-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604537-6
    ISSN 1533-404X ; 0195-7910
    ISSN (online) 1533-404X
    ISSN 0195-7910
    DOI 10.1097/PAF.0000000000000613
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Delayed-Onset Portal Venous Thrombosis After Ingestion of 3% Hydrogen Peroxide.

    Schneir, Aaron / Minns, Alicia B / Otter, Jenna

    The Journal of emergency medicine

    2021  Volume 61, Issue 5, Page(s) 536–539

    Abstract: Background: Identification of portal venous gas on radiographic imaging is well documented after the ingestion of hydrogen peroxide, as is its resolution after hyperbaric therapy. Although hyperbaric therapy may resolve the gastrointestinal symptoms ... ...

    Abstract Background: Identification of portal venous gas on radiographic imaging is well documented after the ingestion of hydrogen peroxide, as is its resolution after hyperbaric therapy. Although hyperbaric therapy may resolve the gastrointestinal symptoms associated with the presence of portal venous gas, the principle rationale for performing hyperbaric therapy is to prevent subsequent central nervous system oxygen embolization.
    Case report: We describe a patient with portal venous gas identified by computed tomography after the ingestion of 3% hydrogen peroxide, managed without hyperbaric therapy, who subsequently developed portal venous thrombosis. We are not aware of this complication being previously described from hydrogen peroxide ingestion. The case is complicated by the coexistence of a self-inflicted stab wound, leading to exploratory laparotomy in a patient predisposed to arterial vascular occlusion. Why Should an EmergencyPhysicianBeAware of This? Emergency physicians will encounter patients after the ingestion of hydrogen peroxide who, despite not having symptoms of central nervous system emboli, have portal venous gas identified on radiographic imaging. Being aware that the principle rationale for prophylactic utilization of hyperbaric therapy is to prevent subsequent central nervous system emboli, and that in at least one case, delayed-onset portal venous thrombosis has occurred without hyperbaric therapy may help contribute to clinical decision-making.
    MeSH term(s) Eating ; Embolism, Air/etiology ; Embolism, Air/therapy ; Humans ; Hydrogen Peroxide/adverse effects ; Hyperbaric Oxygenation ; Portal Vein/diagnostic imaging ; Venous Thrombosis/etiology
    Chemical Substances Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2021-09-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2021.07.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Swipe Right: a Comparison of Accuracy of Plant Identification Apps for Toxic Plants.

    Otter, Jenna / Mayer, Stephanie / Tomaszewski, Christian A

    Journal of medical toxicology : official journal of the American College of Medical Toxicology

    2020  Volume 17, Issue 1, Page(s) 42–47

    Abstract: Introduction: Plant identification applications for use on smartphones have been increasing in availability, accuracy, and utilization. We aimed to perform an introductory study to determine if a plant identification application (ID app) used on a ... ...

    Abstract Introduction: Plant identification applications for use on smartphones have been increasing in availability, accuracy, and utilization. We aimed to perform an introductory study to determine if a plant identification application (ID app) used on a smartphone could identify toxic plants, and to compare apps to determine which is most reliable.
    Methods: We compared three popular iPhone plant ID apps, PictureThis (PT), PlantSnap (PS), and Pl@ntNet (PN), used to identify 17 commonly encountered toxic plants. Apps were used to photograph the entire plant, leaves, and flowers of ≥ 10 different plants for each species. Two toxicologists performed plant identification with confirmation of identification performed by a botanist, and inter-researcher agreement was confirmed. For each plant species, scores for accuracy of app identification of leaves, flowers, and whole plant were combined to create an overall composite score used to compare accuracy of each app (95% C.I.).
    Results: PictureThis had the best performance with 10/17 (59% [36 to 78]) plant species identified 100% correctly, as opposed to 8/17 (47% [26 to 69]) for Pl@ntNet and 1/17 for PlantSnap (5.8% [1.1 to 27]).
    Conclusion: A plant identification app may be a useful tool to assist healthcare providers and the public in identifying toxic plants.
    MeSH term(s) Botany ; Humans ; Mobile Applications ; Observer Variation ; Photography ; Plants, Toxic/adverse effects ; Plants, Toxic/classification ; Smartphone ; Toxicology
    Language English
    Publishing date 2020-08-13
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2435016-3
    ISSN 1937-6995 ; 1556-9039
    ISSN (online) 1937-6995
    ISSN 1556-9039
    DOI 10.1007/s13181-020-00803-6
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    Zs.A 6682: Show issues Location:
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  5. Article ; Online: Prevalence of Acute Hypersensitivity Reactions in Pediatric Patients Receiving Crotalidae Polyvalent Immune Fab.

    Corbett, Bryan / Otter, Jenna / Masom, Clifford P / Clark, Richard F

    Journal of medical toxicology : official journal of the American College of Medical Toxicology

    2020  Volume 17, Issue 1, Page(s) 48–50

    Abstract: Introduction: Studies of acute hypersensitivity reactions in pediatric populations receiving Crotalidae Polyvalent Immune Fab (CPIF) are complicated by small size, wide age ranges, and diverse definitions of such reactions.: Methods: This is a ... ...

    Abstract Introduction: Studies of acute hypersensitivity reactions in pediatric populations receiving Crotalidae Polyvalent Immune Fab (CPIF) are complicated by small size, wide age ranges, and diverse definitions of such reactions.
    Methods: This is a retrospective chart review of patients aged 13 years or younger treated with CPIF for Crotalid envenomation from November 2006 to 2016. The primary outcome was the presence of an acute hypersensitivity reaction to CPIF and was defined as the development of any of the following symptoms within 3 hours of initiation of CPIF infusion: urticaria, wheezing or respiratory distress, angioedema, hypotension, nausea, and/or vomiting. Demographics, CPIF dose to control and total dose, bite location, level of care, and length of stay were also recorded.
    Results: Thirty-four patients were ultimately treated with CPIF. Ages ranged from 10 months to 13 years. Twenty-one patients (60%) were male, 24 (70.6%) were admitted to the ICU, and the median length of stay was 2 days with a range of 1-11 days. Zero patients developed an acute hypersensitivity reaction to CPIF.
    Conclusion: Acute hypersensitivity reactions to CPIF did not occur in this cohort. Such reactions are rare with the use of CPIF in pediatric patients.
    MeSH term(s) Adolescent ; Age Factors ; Animals ; Antivenins/adverse effects ; Child ; Child, Preschool ; Crotalid Venoms/antagonists & inhibitors ; Crotalid Venoms/immunology ; Crotalinae ; Drug Hypersensitivity/diagnosis ; Drug Hypersensitivity/epidemiology ; Drug Hypersensitivity/immunology ; Female ; Humans ; Immunoglobulin Fab Fragments/adverse effects ; Infant ; Male ; Prevalence ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Snake Bites/diagnosis ; Snake Bites/drug therapy ; Snake Bites/epidemiology ; Snake Bites/immunology ; Time Factors ; Treatment Outcome
    Chemical Substances Antivenins ; Crotalid Venoms ; Crotalidae Polyvalent immune Fab ; Immunoglobulin Fab Fragments
    Language English
    Publishing date 2020-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2435016-3
    ISSN 1937-6995 ; 1556-9039
    ISSN (online) 1937-6995
    ISSN 1556-9039
    DOI 10.1007/s13181-020-00798-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Commentary.

    Garg, Manish / Otter, Jenna / Healy, Megan

    Annals of emergency medicine

    2016  Volume 69, Issue 1, Page(s) 135–136

    MeSH term(s) Humans ; Prevalence ; Sepsis ; Vital Signs
    Language English
    Publishing date 2016-12-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 603080-4
    ISSN 1097-6760 ; 0196-0644
    ISSN (online) 1097-6760
    ISSN 0196-0644
    DOI 10.1016/j.annemergmed.2016.10.017
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  7. Article ; Online: A fluvoxamine-related fatality: Case report with postmortem concentrations.

    Otter, Jenna / McIntyre, Iain M / Morhaime, Jacquelyn / Cantrell, Lee

    Forensic science international

    2019  Volume 300, Page(s) e31–e33

    Abstract: Fluvoxamine is a selective serotonin reuptake inhibitor that has been considered relatively safe in overdose. At therapeutic and supratherapeutic concentrations, fluvoxamine affects cardiac conduction, prolongs QTc interval, causes hypotension, ... ...

    Abstract Fluvoxamine is a selective serotonin reuptake inhibitor that has been considered relatively safe in overdose. At therapeutic and supratherapeutic concentrations, fluvoxamine affects cardiac conduction, prolongs QTc interval, causes hypotension, obtundation, and can increase propensity for seizures. A man in his 60s was found dead at his home with a postmortem fluvoxamine peripheral blood concentration of 4.9 mg/L, and a liver concentration of 440 mg/kg. His cause of death was determined to be acute fluvoxamine toxicity.
    MeSH term(s) Drug Overdose ; Fluvoxamine/analysis ; Fluvoxamine/poisoning ; Gas Chromatography-Mass Spectrometry ; Humans ; Limit of Detection ; Liver/chemistry ; Male ; Middle Aged ; Serotonin Uptake Inhibitors/analysis ; Serotonin Uptake Inhibitors/poisoning
    Chemical Substances Serotonin Uptake Inhibitors ; Fluvoxamine (O4L1XPO44W)
    Language English
    Publishing date 2019-03-01
    Publishing country Ireland
    Document type Case Reports ; Journal Article
    ZDB-ID 424042-x
    ISSN 1872-6283 ; 0379-0738
    ISSN (online) 1872-6283
    ISSN 0379-0738
    DOI 10.1016/j.forsciint.2019.02.047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Aortic Thrombus Causing a Hypertensive Emergency.

    Schreyer, Kraftin E / Otter, Jenna / Johnston, Zachary

    Clinical practice and cases in emergency medicine

    2017  Volume 1, Issue 4, Page(s) 387–390

    Abstract: Thoracic aorta thrombi are a rare condition typically presenting as a source for distal embolization in elderly patients with atherosclerotic risk factors. However, young patients with a variety of presentations resulting from such thrombi have rarely ... ...

    Abstract Thoracic aorta thrombi are a rare condition typically presenting as a source for distal embolization in elderly patients with atherosclerotic risk factors. However, young patients with a variety of presentations resulting from such thrombi have rarely been reported. We describe a case of a young patient with refractory hypertensive emergency caused by a large thoracic aorta thrombus. Investigation was guided by abnormal physical exam findings.
    Language English
    Publishing date 2017-11-03
    Publishing country United States
    Document type Case Reports
    ISSN 2474-252X
    ISSN (online) 2474-252X
    DOI 10.5811/cpcem.2017.6.33876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Sulfur Mustard Exposure from Dredged Artillery Shell in a Commercial Clammer.

    Otter, Jenna / Dawood, Alveena / D'Orazio, Joseph

    Clinical practice and cases in emergency medicine

    2017  Volume 1, Issue 4, Page(s) 283–286

    Abstract: A 40-year-old commercial fisherman presented with a blistering second degree burn to the right arm after handling a dredged and undetonated World War I-era sulfur mustard artillery shell. He sustained isolated second degree cutaneous injury requiring ... ...

    Abstract A 40-year-old commercial fisherman presented with a blistering second degree burn to the right arm after handling a dredged and undetonated World War I-era sulfur mustard artillery shell. He sustained isolated second degree cutaneous injury requiring wound care and skin grafting. Sulfur mustard, or dichlorethylsulphide, is a vesicant chemical warfare agent that causes significant cutaneous chemical burn and is managed with burn wound care. Long-term effects include cosmetic disfigurement and increased risk of developing cancer. Sulfur mustard exposure is a rare but devastating injury when discarded artillery shells are encountered in coastal waters.
    Language English
    Publishing date 2017-09-29
    Publishing country United States
    Document type Case Reports
    ISSN 2474-252X
    ISSN (online) 2474-252X
    DOI 10.5811/cpcem.2017.5.34034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A fluvoxamine-related fatality: Case report with postmortem concentrations

    Otter, Jenna / Cantrell, Lee / McIntyre, Iain M / Morhaime, Jacquelyn

    Forensic science international. 2019 July, v. 300

    2019  

    Abstract: Fluvoxamine is a selective serotonin reuptake inhibitor that has been considered relatively safe in overdose. At therapeutic and supratherapeutic concentrations, fluvoxamine affects cardiac conduction, prolongs QTc interval, causes hypotension, ... ...

    Abstract Fluvoxamine is a selective serotonin reuptake inhibitor that has been considered relatively safe in overdose. At therapeutic and supratherapeutic concentrations, fluvoxamine affects cardiac conduction, prolongs QTc interval, causes hypotension, obtundation, and can increase propensity for seizures. A man in his 60s was found dead at his home with a postmortem fluvoxamine peripheral blood concentration of 4.9 mg/L, and a liver concentration of 440 mg/kg. His cause of death was determined to be acute fluvoxamine toxicity.
    Keywords blood ; case studies ; death ; hypotension ; liver ; overdose ; seizures ; serotonin ; toxicity
    Language English
    Dates of publication 2019-07
    Size p. e31-e33.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 424042-x
    ISSN 1872-6283 ; 0379-0738
    ISSN (online) 1872-6283
    ISSN 0379-0738
    DOI 10.1016/j.forsciint.2019.02.047
    Database NAL-Catalogue (AGRICOLA)

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