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  1. Book: Lupusnephritis

    Weinmann-Menke, Julia

    (Auf einen Blick)

    2021  

    Author's details Julia Weinmann-Menke. Mitarbeit Birgit Eschweiler
    Series title Auf einen Blick
    Keywords Systemischer Lupus erythematodes ; Nierenentzündung
    Subject Nephritis ; SLE ; Lupus erythematodes, systemischer ; Systemischer Erythematodes ; Lupus erythematodes visceralis ; Lupus erythematodes disseminatus ; LED ; Systemic lupus erythematosus
    Subject code 616.772
    Language German
    Size 89 Seiten, Illustrationen, 18 cm
    Publisher Ligatur
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT021132828
    ISBN 978-3-940407-73-3 ; 3-940407-73-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 A 247 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: Lupusnephritis – von der Diagnose zur Therapie.

    Weinmann-Menke, Julia

    Innere Medizin (Heidelberg, Germany)

    2023  Volume 64, Issue 3, Page(s) 225–233

    Abstract: Renal involvement in systemic lupus erythematosus (SLE), so-called lupus nephritis (LN), is one of the most frequent organ manifestations with an incidence of approximately 40-60%. It is not uncommon for renal involvement to be the initial manifestation ... ...

    Title translation Lupus nephritis: from diagnosis to treatment.
    Abstract Renal involvement in systemic lupus erythematosus (SLE), so-called lupus nephritis (LN), is one of the most frequent organ manifestations with an incidence of approximately 40-60%. It is not uncommon for renal involvement to be the initial manifestation of SLE or to occur in the first 5-10 years after diagnosis of SLE. Urinalysis is useful in screening for the presence of LN, demonstrating proteinuria or active sediment with acanthocytes. Histologic confirmation of LN, and thus the LN class present, is currently the gold standard for confirming the diagnosis. In addition, knowledge of the LN class is a relevant component of adequate treatment planning in SLE patients with LN. In particular, early diagnosis and rapid response to therapy are of prognostic importance for the preservation of renal function as well as morbidity and mortality of the mostly young patients at the time of initial diagnosis. Thus, the focus of therapy is to achieve complete remission, as well as to avoid active disease phases. Due to a complex pathogenesis and at the same time a very heterogeneous clinical presentation, with six different histological classes of LN, there are different therapeutic targets. This in turn results in a significant expansion of the study landscape in the field of LN with an increasing understanding of the signaling pathways and influencing factors, and fortunately in a growing armamentarium of available targeted therapy options. Simultaneously, new insights into drug therapy to inhibit progression of chronic renal disease are opening up supportive therapy options that can further improve preservation of renal function.
    MeSH term(s) Humans ; Lupus Nephritis/diagnosis ; Lupus Erythematosus, Systemic/complications ; Kidney Failure, Chronic/etiology ; Prognosis ; Biopsy/adverse effects
    Language German
    Publishing date 2023-02-10
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7099
    ISSN (online) 2731-7099
    DOI 10.1007/s00108-023-01489-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Lupusnephritis: Therapieziel und -strategie

    Weinmann-Menke, Julia

    Nephrologie aktuell

    2023  Volume 27, Issue 03, Page(s) 104–108

    Abstract: Die Nierenbeteiligung bei systemischem Lupus erythematodes (SLE) ist mit einer Inzidenz von ca. 40–60 % eine der häufigsten Organmanifestationen. Die histologische Sicherung der Lupusnephritis (LN) und damit der LN-Klasse ist zurzeit der Goldstandard der ...

    Abstract Die Nierenbeteiligung bei systemischem Lupus erythematodes (SLE) ist mit einer Inzidenz von ca. 40–60 % eine der häufigsten Organmanifestationen. Die histologische Sicherung der Lupusnephritis (LN) und damit der LN-Klasse ist zurzeit der Goldstandard der Diagnosesicherung. Das Wissen über die LN-Klasse ist ein relevanter Bestandteil der adäquaten Therapieplanung bei Patienten mit LN. Hier ist insbesondere die frühe Diagnosestellung als auch das rasche Ansprechen auf die eingesetzten Therapien von prognostischer Bedeutung für den Erhalt der Nierenfunktion sowie die Morbidität und Mortalität der Patienten.:
    Language German
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 3131412-0
    ISSN 2751-9139 ; 2751-9120
    ISSN (online) 2751-9139
    ISSN 2751-9120
    DOI 10.1055/a-2008-1740
    Database Thieme publisher's database

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  4. Article ; Online: Care about the flare: the importance of avoiding lupus nephritis recurrence.

    Weinmann-Menke, Julia / Kraus, Daniel

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2022  Volume 38, Issue 4, Page(s) 800–802

    MeSH term(s) Humans ; Lupus Nephritis/therapy ; Prognosis
    Language English
    Publishing date 2022-12-26
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfac323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 329: Show issues

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  5. Article ; Online: Capillary rarefication as a possible cause of long-COVID syndrome.

    Osiaevi, Irina / Kümpers, Philipp / Weinmann-Menke, Julia / Pavenstädt, Hermann / Rovas, Alexandros

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2024  

    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfae026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Mouse models, antibodies, and neuroimaging: Current knowledge and future perspectives in neuropsychiatric systemic lupus erythematosus (NPSLE).

    Tomalla, Vanessa / Schmeisser, Michael J / Weinmann-Menke, Julia

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1078607

    Abstract: As a chronic autoimmune disease systemic lupus erythematosus (SLE) can also affect the central and the peripheral nervous system causing symptoms which are summed up as neuropsychiatric systemic lupus erythematosus (NPSLE). These symptoms are ... ...

    Abstract As a chronic autoimmune disease systemic lupus erythematosus (SLE) can also affect the central and the peripheral nervous system causing symptoms which are summed up as neuropsychiatric systemic lupus erythematosus (NPSLE). These symptoms are heterogenous including cognitive impairment, seizures, and fatigue, leading to morbidity or even mortality. At present, little is known about the pathophysiological processes involved in NPSLE. This review focuses on the current knowledge of the pathogenesis of NPSLE gained from the investigation of animal models, autoantibodies, and neuroimaging techniques. The antibodies investigated the most are anti-ribosomal P protein antibodies (Anti-rib P) and anti-N-Methyl-D-Aspartic Acid Receptor 2 antibodies (Anti-NR2), which represent a subpopulation of anti-dsDNA autoantibodies. Experimental data demonstrates that Anti-rib P and Anti-NR2 cause different neurological pathologies when applied intravenously (i.v.), intrathecally or intracerebrally in mice. Moreover, the investigation of lupus-prone mice, such as the MRL/MpJ-Fas
    Language English
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1078607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Systemischer Lupus erythematodes und Lupusnephritis: neue Therapiestrategien

    Weinmann-Menke, Julia

    Dialyse aktuell

    2022  Volume 26, Issue 08, Page(s) 352–358

    Abstract: Der systemische Lupus erythematodes (SLE) ist eine Autoimmunerkrankung, welche nahezu jedes Organsystem befallen kann. Die Krankheitsmanifestationen sowie die Verläufe des SLE sind sehr heterogen, eine frühe Diagnosestellung und adäquate Therapie der ... ...

    Abstract Der systemische Lupus erythematodes (SLE) ist eine Autoimmunerkrankung, welche nahezu jedes Organsystem befallen kann. Die Krankheitsmanifestationen sowie die Verläufe des SLE sind sehr heterogen, eine frühe Diagnosestellung und adäquate Therapie der meist jungen Patient*innen ist für die Langzeitprognose ausgesprochen relevant. Neben der klinischen Einschätzung können die im Jahr 2019 neu publizierten Klassifikationskriterien von EULAR/ACR (EULAR: European League Against Rheumatism; ACR: American College of Rheumatology) bei der Diagnosestellung unterstützend zur Hilfe genommen werden. Die Hauptursache für Morbidität und Mortalität der Patient*innen mit SLE ist die Entwicklung einer Lupusnephritis (LN), sodass hier eine frühe Diagnosestellung für die Prognose der Patient*innen unabdingbar ist. Im Mittelpunkt der Therapie steht das Erreichen einer vollständigen Remission bzw. zumindest das Erreichen einer niedrigen Krankheitsaktivität sowie das Vermeiden aktiver Krankheitsphasen, alles möglichst unter dem Verzicht des Einsatzes von Steroiden. Aufgrund der Heterogenität der Erkrankung sind häufig individualisierte Therapieanpassungen erforderlich. Neuere Erkenntnisse über die Pathomechanismen des SLE und der LN haben zur Entwicklung zielgerichteter Therapien („targeted therapies“) geführt, die zunehmend das Therapiespektrum für Patient*innen mit SLE erweitern.
    Language German
    Publishing date 2022-10-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2146225-2
    ISSN 1860-3300 ; 1434-0704
    ISSN (online) 1860-3300
    ISSN 1434-0704
    DOI 10.1055/a-1913-4010
    Database Thieme publisher's database

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  8. Article ; Online: Urine, doctors, and the acanthocyte's 30th birthday.

    Kraus, Daniel / Köhler, Hans / Weinmann-Menke, Julia

    Kidney international

    2022  Volume 101, Issue 2, Page(s) 196–200

    MeSH term(s) Acanthocytes ; Body Fluids ; Hematuria ; Humans ; Kidney Glomerulus ; Urine
    Language English
    Publishing date 2022-01-22
    Publishing country United States
    Document type Editorial
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2021.11.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Conference proceedings: Medizinische und physiotherapeutische Versorgung von Patientinnen und Patienten mit Gonarthrose

    Menke, Chiara Julia

    2020  , Page(s) 20dkvf467

    Event/congress 19. Deutscher Kongress für Versorgungsforschung (DKVF); sine loco [digital]; Deutsches Netzwerk Versorgungsforschung; 2020
    Keywords Medizin, Gesundheit
    Publishing date 2020-09-25
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/20dkvf467
    Database German Medical Science

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  10. Article: Nierenversagen im Rahmen von autoimmunen Systemerkrankungen

    Weinmann-Menke, Julia

    Arthritis + Rheuma

    2020  Volume 40, Issue 6, Page(s) 401

    Language German
    Document type Article
    ZDB-ID 605764-0
    ISSN 0176-5167
    Database Current Contents Medicine

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