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  1. Article ; Online: [No title information]

    Matsumoto, Shinya / Murata, Yuki / Tomoda, Yoshitaka

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2023  Volume 195, Issue 7, Page(s) E288

    Title translation Infection aiguë à VIH chez un homme de 39 ans.
    MeSH term(s) Male ; Humans ; Adult ; HIV Infections
    Language French
    Publishing date 2023-02-21
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.220656-f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.136: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Alleviation of allergic conjunctivitis by (±)5(6)-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid in mice.

    Nagata, Nanae / Suzuki, Tomoka / Takenouchi, Shinya / Kobayashi, Koji / Murata, Takahisa

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1217397

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-09-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1217397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Design, synthesis of ceramide 1-phosphate analogs and their affinity for cytosolic phospholipase A

    Yasuda, Tomokazu / Ueura, Daiki / Nakagomi, Madoka / Hanashima, Shinya / Peter Slotte, J / Murata, Michio

    Bioorganic & medicinal chemistry letters

    2024  , Page(s) 129792

    Abstract: Ceramide 1-phosphate (C1P) is a lipid mediator that specifically binds and activates cytosolic phospholipase ... ...

    Abstract Ceramide 1-phosphate (C1P) is a lipid mediator that specifically binds and activates cytosolic phospholipase A
    Language English
    Publishing date 2024-05-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1063195-1
    ISSN 1464-3405 ; 0960-894X
    ISSN (online) 1464-3405
    ISSN 0960-894X
    DOI 10.1016/j.bmcl.2024.129792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3203: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Acute HIV infection in a 39-year-old man.

    Matsumoto, Shinya / Murata, Yuki / Tomoda, Yoshitaka

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2022  Volume 194, Issue 45, Page(s) E1541

    MeSH term(s) Male ; Humans ; Adult ; HIV Infections/diagnosis ; HIV Infections/drug therapy
    Language English
    Publishing date 2022-11-21
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.220656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.136: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Passive Translocation of Phospholipids in Asymmetric Model Membranes: Solid-State

    Watanabe, Hirofumi / Hanashima, Shinya / Yano, Yo / Yasuda, Tomokazu / Murata, Michio

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 43, Page(s) 15189–15199

    Abstract: Although lateral and inter-leaflet lipid-lipid interactions in cell membranes play roles in maintaining asymmetric lipid bilayers, the molecular basis of these interactions is largely unknown. Here, we established a method to determine the distribution ... ...

    Abstract Although lateral and inter-leaflet lipid-lipid interactions in cell membranes play roles in maintaining asymmetric lipid bilayers, the molecular basis of these interactions is largely unknown. Here, we established a method to determine the distribution ratio of phospholipids between the outer and inner leaflets of asymmetric large unilamellar vesicles (aLUVs). The trimethylammonium group, (CH
    MeSH term(s) Phospholipids/metabolism ; Sphingomyelins ; Proton Magnetic Resonance Spectroscopy ; Lipid Bilayers/chemistry ; Lecithins ; Unilamellar Liposomes/chemistry
    Chemical Substances Phospholipids ; Sphingomyelins ; Lipid Bilayers ; Lecithins ; Unilamellar Liposomes
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c01650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Safety, Tolerability, and Immunogenicity of V160, a Conditionally Replication-Defective Cytomegalovirus Vaccine, in Healthy Japanese Men in a Randomized, Controlled Phase 1 Study.

    Murata, Shinya / Oshima, Nobuyuki / Iwasa, Takashi / Fukao, Yukako / Sawata, Miyuki

    Antibodies (Basel, Switzerland)

    2023  Volume 12, Issue 1

    Abstract: Cytomegalovirus (CMV) infection can cause newborn morbidity and mortality; no pharmacological method of reducing CMV infection during pregnancy is currently available. In a phase 1 study in the United States, V160, a conditionally replication-defective ... ...

    Abstract Cytomegalovirus (CMV) infection can cause newborn morbidity and mortality; no pharmacological method of reducing CMV infection during pregnancy is currently available. In a phase 1 study in the United States, V160, a conditionally replication-defective CMV vaccine, was immunogenic and well tolerated. This placebo-controlled study (NCT03840174) investigated the safety and immunogenicity of a three-dose V160 vaccine administered over six months. A total of 18 healthy adult Japanese males (9 seronegative and 9 seropositive) were enrolled at a single center and randomized 2:1 to intramuscular V160 or placebo. In vitro, V160 induced high CMV-specific neutralizing antibody (NAb) titers (50% neutralization titer [NT
    Language English
    Publishing date 2023-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661514-9
    ISSN 2073-4468 ; 2073-4468
    ISSN (online) 2073-4468
    ISSN 2073-4468
    DOI 10.3390/antib12010022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Symptom Improvement of ulceRative colitis after an Induction dose of UStekinumab in Japanese clinical practice (SIRIUS), measured using patient-reported outcomes

    Katsuyoshi Matsuoka / Tadakazu Hisamatsu / YOKO MURATA / Katsumasa Nagano / Shinya Nagasaki

    BMJ Open, Vol 12, Iss

    a prospective observational study

    2022  Volume 5

    Keywords Medicine ; R
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Myricetin causes site-specific DNA damage via reactive oxygen species generation by redox interactions with copper ions.

    Hirao, Yuichiro / Kobayashi, Hatasu / Mori, Yurie / Kato, Shinya / Kawanishi, Shosuke / Murata, Mariko / Oikawa, Shinji

    Mutation research. Genetic toxicology and environmental mutagenesis

    2023  Volume 891, Page(s) 503694

    Abstract: Myricetin (MYR), found in tea and berries, may have preventive effects on diseases, including Alzheimer's disease and cancer. However, MYR is also a mutagen, inducing DNA damage in the presence of metal ions. We have studied the molecular mechanisms of ... ...

    Abstract Myricetin (MYR), found in tea and berries, may have preventive effects on diseases, including Alzheimer's disease and cancer. However, MYR is also a mutagen, inducing DNA damage in the presence of metal ions. We have studied the molecular mechanisms of DNA damage by MYR in the presence of Cu(II) (MYR+Cu). Using
    Language English
    Publishing date 2023-09-18
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-3592
    ISSN (online) 1879-3592
    DOI 10.1016/j.mrgentox.2023.503694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Lipid chain-driven interaction of a lipidated Src-family kinase Lyn with the bilayer membrane.

    Hanashima, Shinya / Mito, Kanako / Umegawa, Yuichi / Murata, Michio / Hojo, Hironobu

    Organic & biomolecular chemistry

    2022  Volume 20, Issue 32, Page(s) 6436–6444

    Abstract: ... ...

    Abstract N
    MeSH term(s) Cell Membrane/metabolism ; Lipid Bilayers/chemistry ; Peptides/chemistry ; Phospholipids ; src-Family Kinases/chemistry ; src-Family Kinases/metabolism
    Chemical Substances Lipid Bilayers ; Peptides ; Phospholipids ; src-Family Kinases (EC 2.7.10.2)
    Language English
    Publishing date 2022-08-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d2ob01079h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Oxidative DNA damage: Induction by fructose, in vitro, and its enhancement by hydrogen peroxide.

    Midorikawa, Kaoru / Kobayashi, Kokoro / Kato, Shinya / Kawanishi, Shosuke / Kobayashi, Hatasu / Oikawa, Shinji / Murata, Mariko

    Mutation research. Genetic toxicology and environmental mutagenesis

    2023  Volume 893, Page(s) 503719

    Abstract: Sucrose and high-fructose corn syrup comprise nearly equal amounts of glucose and fructose. With the use of high-fructose corn syrup in the food industry, consumption of fructose, which may be a tumor promoter, has increased dramatically. We examined ... ...

    Abstract Sucrose and high-fructose corn syrup comprise nearly equal amounts of glucose and fructose. With the use of high-fructose corn syrup in the food industry, consumption of fructose, which may be a tumor promoter, has increased dramatically. We examined fructose-induced oxidative DNA damage in the presence of Cu(II), with or without the addition of H
    MeSH term(s) Humans ; 8-Hydroxy-2'-Deoxyguanosine ; Deoxyguanosine ; Hydrogen Peroxide/toxicity ; Oxidative Stress ; DNA Damage ; Glucose ; Copper/pharmacology ; Oxidation-Reduction
    Chemical Substances 8-Hydroxy-2'-Deoxyguanosine (88847-89-6) ; Deoxyguanosine (G9481N71RO) ; Hydrogen Peroxide (BBX060AN9V) ; Glucose (IY9XDZ35W2) ; Copper (789U1901C5)
    Language English
    Publishing date 2023-11-26
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-3592
    ISSN (online) 1879-3592
    DOI 10.1016/j.mrgentox.2023.503719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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