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  1. Article ; Online: Supportive treatment of COVID 19 patients with mild respiratory failure in a primary hospital.

    Martín Raymondi, Diego / Hernández, Luis

    Medicina clinica (English ed.)

    2020  Volume 155, Issue 5, Page(s) 222–223

    Keywords covid19
    Language English
    Publishing date 2020-09-19
    Publishing country Spain
    Document type Case Reports
    ISSN 2387-0206
    ISSN (online) 2387-0206
    DOI 10.1016/j.medcle.2020.06.003
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  2. Article ; Online: Supportive treatment of COVID 19 patients with mild respiratory failure in a primary hospital.

    Martín Raymondi, Diego / Hernández, Luis

    Medicina clinica

    2020  Volume 155, Issue 5, Page(s) 222–223

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Conservative Treatment/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/mortality ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Hospitals ; Humans ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/mortality ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Primary Health Care ; Respiratory Insufficiency/diagnosis ; Respiratory Insufficiency/mortality ; Respiratory Insufficiency/therapy ; Respiratory Insufficiency/virology ; Respiratory Therapy/methods ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index ; Spain/epidemiology ; Treatment Outcome
    Keywords covid19
    Language Spanish
    Publishing date 2020-06-11
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.06.008
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  3. Article ; Online: Supportive treatment of COVID 19 patients with mild respiratory failure in a primary hospital

    Martín Raymondi, Diego / Hernández, Luis

    Medicina Clínica (English Edition)

    2020  Volume 155, Issue 5, Page(s) 222–223

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2387-0206
    DOI 10.1016/j.medcle.2020.06.003
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Supportive treatment of COVID 19 patients with mild respiratory failure in a primary hospital

    Martín Raymondi, Diego / Hernández, Luis

    Medicina Clínica

    2020  Volume 155, Issue 5, Page(s) 222–223

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.06.008
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  5. Article ; Online: Detection of High-sensitivity Troponin T in Patients With Cardiovascular Risk. Response.

    Álvarez Nozal, Isabel / García Pardo, Héctor / Martín Raymondi, Diego

    Revista espanola de cardiologia (English ed.)

    2017  Volume 70, Issue 7, Page(s) 616

    Language Spanish
    Publishing date 2017-07
    Publishing country Spain
    Document type Letter
    ISSN 1885-5857
    ISSN (online) 1885-5857
    DOI 10.1016/j.rec.2017.04.004
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  6. Article ; Online: TUSARC: Prognostic Value of High-Sensitivity Cardiac Troponin T Assay in Asymptomatic Patients with High Cardiovascular Risk.

    Martín Raymondi, Diego / Garcia, Héctor / Álvarez, Isabel / Hernández, Luis / Molinero, Jorge Palazuelos / Villamandos, Vicente

    The American journal of medicine

    2018  Volume 132, Issue 5, Page(s) 631–638

    Abstract: Background: Prognostic value of high-sensitivity cardiac troponin T (hs-cTnT) assays have been assessed in selected populations in different studies and in registries of members of the general population with low cardiovascular risk. The aim of this ... ...

    Abstract Background: Prognostic value of high-sensitivity cardiac troponin T (hs-cTnT) assays have been assessed in selected populations in different studies and in registries of members of the general population with low cardiovascular risk. The aim of this study was to determine the prognostic value of hs-cTnT in an asymptomatic very-high cardiovascular risk Spanish population.
    Methods: From a previous prospective cohort of the TUSARC (troponina T UltraSensible en pacientes Asintomáticos de alto Riesgo Cardiovascular) registry, follow-up was conducted in 602 patients (93.18%). The association of high hs-cTnT (≥99th percentile value) and incidence of primary event was studied. A primary event was defined as a combined major cardiovascular event (incidence of cardiovascular death, decompensated heart failure, non-fatal cerebrovascular event, non-fatal myocardial infarction, or coronary revascularization). The association between high hs-cTnT and incidence of secondary events was studied as well.
    Results: In patients with high hs-cTnT, the incidence of primary event during follow-up was significantly higher (18.30% vs 3.67% P < .001): heart failure (6.25% vs 0.73% P < .001), cardiovascular death (7.29% vs 0.00% P < .001), and death from any cause (7.81% vs 0.98% P < .001).
    Conclusions: In an asymptomatic very-high cardiovascular risk Spanish population, elevated hs-cTnT was significantly associated with incident major cardiovascular combined end point and incidence of heart failure, cardiovascular death, and death from any cause.
    MeSH term(s) Aged ; Biomarkers/blood ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/mortality ; Female ; Heart Failure/blood ; Heart Failure/diagnosis ; Heart Failure/mortality ; Humans ; Incidence ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Registries/statistics & numerical data ; Risk Assessment/methods ; Risk Factors ; Spain/epidemiology ; Troponin T/blood
    Chemical Substances Biomarkers ; Troponin T
    Language English
    Publishing date 2018-12-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2018.11.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: High-sensitivity Troponin T Assay in Asymptomatic High Cardiovascular Risk Patients. The TUSARC Registry.

    Álvarez, Isabel / Hernández, Luis / García, Héctor / Villamandos, Vicente / López, María Gracia / Palazuelos Molinero, Jorge / Martín Raymondi, Diego

    Revista espanola de cardiologia (English ed.)

    2017  Volume 70, Issue 4, Page(s) 261–266

    Abstract: Introduction and objectives: High-sensitivity troponin T assays (Hs-TnT) have been carried out in selected populations in clinical trials and in registries of the general population with low cardiovascular risk (CVR). The aim of this study was to ... ...

    Abstract Introduction and objectives: High-sensitivity troponin T assays (Hs-TnT) have been carried out in selected populations in clinical trials and in registries of the general population with low cardiovascular risk (CVR). The aim of this study was to determine the proportion of individuals with detectable Hs-TnT and the proportion of individuals with elevated Hs-TnT in a Spanish population of asymptomatic individuals with very high CVR, as well as the parameters associated with Hs-TnT elevation.
    Methods: The study included 690 patients. Hs-TnT detection and Hs-TnT elevation (≥99th percentile value), as well the association of elevated Hs-TnT and clinical, analytical, and treatment data were analyzed.
    Results: Hs-TnT was analyzed in 646 patients and was detected in 645. Elevated TnT was detected in 212 patients (32.9%). On multivariate analysis, elevated TnT was independently associated with male sex (OR, 2.81; 95%CI, 1.67-4.73; P < .001), older age (OR, 1.06; 95%CI, 1.04-1.09; P < .001), a higher body mass index (OR, 1.07; 95%CI, 1.02-1.12; P < .002), insulin therapy (OR, 1.99; 95%CI, 1.15-3.46; P = .01), history of heart failure (OR, 3.92; 95%CI, 1.24-12.39; P = .02), and estimated glomerular filtration rate calculated by CKD-EPI (OR, 0.96; 95%CI, 0.95-0.97; P < .001).
    Conclusions: In a Spanish population of asymptomatic individuals at very high CVR, Hs-TnT was associated with older age, male sex, higher body mass index, insulin therapy, history of heart failure, and lower glomerular filtration rate.
    MeSH term(s) Biological Assay ; Biomarkers/metabolism ; Cardio-Renal Syndrome/diagnosis ; Cardio-Renal Syndrome/epidemiology ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Early Diagnosis ; Female ; Glomerular Filtration Rate/physiology ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Humans ; Hypertrophy, Left Ventricular/diagnosis ; Hypertrophy, Left Ventricular/epidemiology ; Male ; Middle Aged ; Prospective Studies ; Registries ; Risk Factors ; Sensitivity and Specificity ; Spain/epidemiology ; Troponin T/metabolism
    Chemical Substances Biomarkers ; Troponin T
    Language Spanish
    Publishing date 2017-04
    Publishing country Spain
    Document type Journal Article
    ISSN 1885-5857
    ISSN (online) 1885-5857
    DOI 10.1016/j.rec.2016.11.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Características de la cardiopatía hipertensiva en pacientes con hipertensión arterial no tratados previamente.

    Martín Raymondi, Diego / Díaz Dorronsoro, Inés / Barba, Joaquín / Díez, Javier

    Medicina clinica

    2005  Volume 125, Issue 9, Page(s) 321–324

    Abstract: Background and objective: Although impaired diastolic function is frequently found in systemic hypertension, the diagnosis of hypertensive heart disease (HHD) is based on the demonstration of left ventricular (LV) growth. The aim of the current work was ...

    Title translation Characteristics of hypertensive cardiomyopathy in a population of hypertensive patients never treated.
    Abstract Background and objective: Although impaired diastolic function is frequently found in systemic hypertension, the diagnosis of hypertensive heart disease (HHD) is based on the demonstration of left ventricular (LV) growth. The aim of the current work was to investigate the potential interactions between diastolic function and LV growth in patients with arterial hypertension.
    Patients and method: One hundred and sixteen never-treated asymptomatic hypertensives underwent an echocardiographic evaluation. Classification of diastolic dysfunction (DD) was based on alterations in parameters assessing transmitral inflow, Doppler tissue imaging of mitral annular motion, and color M-mode propagation velocity. Classification of LV growth was based on alterations in left ventricular mass index and/or relative will thickness.
    Results: Ninety-four patients (81%) exhibited DD and 22 (19%) exhibited normal diastolic function. Amongst patients with DD, 79 (84%) exhibited a pattern of impaired relaxation and 15 (16%) a pseudonormal pattern. The presence of LV growth was documented in 41% of patients without DD and 75% of patients with DD (p < 0.05). None of the studied patients exhibited echocardiographic signs of systolic dysfunction.
    Conclusions: These findings indicate that DD is an early and highly frequent cardiac alteration in arterial hypertension. In addition, our data show that one fifth of hypertensive patients have DD in the absence of LV growth. It is thus suggested that the diagnosis of HHD can not be further based exclusively on morphologic criteria and should include also the evaluation of alterations in LV filling.
    MeSH term(s) Adult ; Aged ; Diastole ; Female ; Humans ; Hypertension/physiopathology ; Hypertrophy, Left Ventricular/diagnosis ; Hypertrophy, Left Ventricular/etiology ; Male ; Middle Aged ; Ventricular Dysfunction, Left/diagnosis ; Ventricular Dysfunction, Left/etiology ; Ventricular Remodeling
    Language Spanish
    Publishing date 2005-09-12
    Publishing country Spain
    Document type English Abstract ; Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1157/13078771
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  9. Article: Angina con ascenso del segmento ST durante la fase de recuperación de un ecocardiograma de estrés con dobutamina.

    Martín Raymondi, Diego / Díaz Dorronsoro, Inés / Fernández Alonso, Leopoldo / Barba Cosials, Joaquín

    Medicina clinica

    2004  Volume 123, Issue 15, Page(s) 598–599

    Title translation Angina with ST segment elevation during resting phase of dobutamine stress.
    MeSH term(s) Angina Pectoris/complications ; Angina Pectoris/diagnosis ; Arrhythmias, Cardiac/complications ; Arrhythmias, Cardiac/diagnosis ; Cardiotonic Agents/administration & dosage ; Dobutamine/administration & dosage ; Exercise Test ; Humans ; Male ; Middle Aged ; Rest
    Chemical Substances Cardiotonic Agents ; Dobutamine (3S12J47372)
    Language Spanish
    Publishing date 2004-10-13
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1157/13068014
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  10. Article ; Online: Short-term metabolic changes achieved by weight loss in hypertensive patients.

    Cordero, Alberto / Bertomeu-Martínez, Vicente / Mazón, Pilar / Martín-Raymondi, Diego / Palma, Jose Luis / Anguita, Manuel / Lekuona, Iñaki / Galve, Enrique / González-Juanatey, José R

    International journal of cardiology

    2011  Volume 153, Issue 3, Page(s) 286–290

    Abstract: Introduction: Glucose and lipid metabolism abnormalities of hypertensive patients are highly relevant due to its increase in cardiovascular risk; moreover, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) have a high risk of new-onset ...

    Abstract Introduction: Glucose and lipid metabolism abnormalities of hypertensive patients are highly relevant due to its increase in cardiovascular risk; moreover, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) have a high risk of new-onset diabetes mellitus (DM) development. The objective of the study was to describe glucose metabolism abnormalities and the impact of mid-term weight loss.
    Methods: A six-month prospective, observational and multicentre study of patients with hypertension was conducted. Clinical antecedents, physical examination, blood test and treatments were collected in two separated visits; conventional advice was the only intervention planned.
    Results: A total of 1957 patients were included, mean age 66.3 (10.9) years and 59.9% males. A previous diagnosis of glucose metabolism alteration was present in 43.9% (25.5% type-2 DM, 14.8% IFG, 1.6% IFG and IGT, 1.0% IGT and 1.0% type-1 DM). An increasing pattern of cardiovascular risk and target organ damage was observed according to the categories of fasting glucose. Oral glucose tolerance test (OGTT) was carried out in 234 patients (11.9%) patients and yielded the diagnosis of IGT in 44.7% or DM in 22.4% of patients with fasting glucose >100mg/dl. Six months follow-up was achieved in 85.9% patients. A slight reduction in fasting glucose was observed in the whole cohort and patients who achieved ≥ 5% weight loss experienced the highest reduction in fasting glucose, LDL-c and triglycerides; moreover, 15.8% normalized their IFG.
    Conclusions: Glucose and lipid metabolism abnormalities are highly prevalent in hypertensive patients and improve with 5% of weight lost at 6 months follow-up. OGTT is not currently extended in daily clinical practise.
    MeSH term(s) Aged ; Blood Glucose/metabolism ; Cohort Studies ; Female ; Follow-Up Studies ; Glucose Intolerance/blood ; Glucose Intolerance/diagnosis ; Glucose Intolerance/therapy ; Glucose Tolerance Test/methods ; Humans ; Hypertension/blood ; Hypertension/diagnosis ; Hypertension/therapy ; Lipid Metabolism/physiology ; Male ; Middle Aged ; Prospective Studies ; Registries ; Time Factors ; Weight Loss/physiology
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2011-12-15
    Publishing country Netherlands
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2010.08.051
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