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  1. Article ; Online: Reverse effects of

    Huang, Lijia / Lu, Wenhua / Ning, Yang / Liu, Jia

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 1023457

    Abstract: Bacteria in nature are present in different lifestyles with distinct characteristics. ...

    Abstract Bacteria in nature are present in different lifestyles with distinct characteristics.
    MeSH term(s) Mice ; Animals ; Extracellular Traps/metabolism ; Neutrophils ; Streptococcus mutans ; Dental Caries ; Biofilms
    Language English
    Publishing date 2022-11-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.1023457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Study on Removal Mechanism for Copper Cyanide Complex Ions in Water: Ion Species Differences and Evolution Process.

    Liu, Ying / Sun, Baogang / Jia, Wenting / Wang, Yuan / Huang, Lijia / Ning, Pengge / Yuan, Shaojun

    International journal of molecular sciences

    2023  Volume 24, Issue 6

    Abstract: A large amount of cyanide-containing wastewater is discharged during electrode material synthesis. Among them, cyanides will form metal-cyanide complex ions which possess high stability, making it challenging to separate them from these wastewaters. ... ...

    Abstract A large amount of cyanide-containing wastewater is discharged during electrode material synthesis. Among them, cyanides will form metal-cyanide complex ions which possess high stability, making it challenging to separate them from these wastewaters. Therefore, it is imperative to understand the complexation mechanism of cyanide ions and heavy metal ions from wastewater in order to obtain a deep insight into the process of cyanide removal. This study employs Density Functional Theory (DFT) calculations to reveal the complexation mechanism of metal-cyanide complex ions formed by the interaction of Cu
    MeSH term(s) Wastewater ; Copper/chemistry ; Cyanides/chemistry ; Water ; Species Specificity ; Coordination Complexes ; Ions ; Water Pollutants, Chemical/chemistry
    Chemical Substances Wastewater ; Copper (789U1901C5) ; Cyanides ; Water (059QF0KO0R) ; Coordination Complexes ; Ions ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-03-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24065066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion.

    Jia, Shilin / Mai, Lijia / Yang, Hui / Huang, Fang / He, Hongwen / Fan, Wenguo

    Life sciences

    2023  Volume 332, Page(s) 122130

    Abstract: Purinergic signaling system plays a pivotal role in the trigeminal ganglion (TG) which is a primary sensory tissue in vertebrate nervous systems involving orofacial nociception and peripheral sensitization. Despite previous efforts to reveal the ... ...

    Abstract Purinergic signaling system plays a pivotal role in the trigeminal ganglion (TG) which is a primary sensory tissue in vertebrate nervous systems involving orofacial nociception and peripheral sensitization. Despite previous efforts to reveal the expression patterns of purinergic components in the mouse TG, it is still unknown the interspecies differences between human and mouse. In this study, we provide a comprehensive transcriptome profile of the purinergic signaling system across diverse cell types and neuronal subpopulations within the human TG, systematically comparing it with mouse TG. In addition, the evolutionary conservation and species-specific expression patterns of the purinergic components are also discussed. We propose that the data can improve our understanding of purinergic signaling in the peripheral nervous system and facilitate the identification of novel therapeutic targets.
    Language English
    Publishing date 2023-09-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 3378-9
    ISSN 1879-0631 ; 0024-3205
    ISSN (online) 1879-0631
    ISSN 0024-3205
    DOI 10.1016/j.lfs.2023.122130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Preparation of wavy three-dimensional graphene-like biochar and its adsorption mechanism of embedded separation for dimethoate.

    Qiu, Lijia / Zong, Xufang / Yuan, Rongfang / Zhou, Beihai / Chen, Huilun / Zhang, Jia

    Journal of hazardous materials

    2023  Volume 458, Page(s) 131893

    Abstract: In this study, graphene-like biochar (IZBC) was prepared by pyrolysis of wheat straw in the presence of catalyst and activator. The formation of graphene in IZBC could be divided into three stages: shell core generation, carburization, and carbon ... ...

    Abstract In this study, graphene-like biochar (IZBC) was prepared by pyrolysis of wheat straw in the presence of catalyst and activator. The formation of graphene in IZBC could be divided into three stages: shell core generation, carburization, and carbon precipitation. When the pyrolysis temperatures were in the ranges of 500-600 ℃, 600-700 ℃, 700-800 ℃ and 800-900 ℃, 17%, 32%, 13% and 38% of graphene were produced, respectively. The contribution ratios of graphene by FeCl
    Language English
    Publishing date 2023-06-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.131893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Porphyromonas gingivalis aggravates colitis via a gut microbiota-linoleic acid metabolism-Th17/Treg cell balance axis.

    Jia, Lu / Jiang, Yiyang / Wu, Lili / Fu, Jingfei / Du, Juan / Luo, Zhenhua / Guo, Lijia / Xu, Junji / Liu, Yi

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 1617

    Abstract: Periodontitis is closely related to inflammatory bowel disease (IBD). An excessive and non-self-limiting immune response to the dysbiotic microbiome characterizes the two. However, the underlying mechanisms that overlap still need to be clarified. We ... ...

    Abstract Periodontitis is closely related to inflammatory bowel disease (IBD). An excessive and non-self-limiting immune response to the dysbiotic microbiome characterizes the two. However, the underlying mechanisms that overlap still need to be clarified. We demonstrate that the critical periodontal pathogen Porphyromonas gingivalis (Pg) aggravates intestinal inflammation and Th17/Treg cell imbalance in a gut microbiota-dependent manner. Specifically, metagenomic and metabolomic analyses shows that oral administration of Pg increases levels of the Bacteroides phylum but decreases levels of the Firmicutes, Verrucomicrobia, and Actinobacteria phyla. Nevertheless, it suppresses the linoleic acid (LA) pathway in the gut microbiota, which was the target metabolite that determines the degree of inflammation and functions as an aryl hydrocarbon receptor (AHR) ligand to suppress Th17 differentiation while promoting Treg cell differentiation via the phosphorylation of Stat1 at Ser727. Therapeutically restoring LA levels in colitis mice challenged with Pg exerts anti-colitis effects by decreasing the Th17/Treg cell ratio in an AHR-dependent manner. Our study suggests that Pg aggravates colitis via a gut microbiota-LA metabolism-Th17/Treg cell balance axis, providing a potential therapeutically modifiable target for IBD patients with periodontitis.
    MeSH term(s) Humans ; Mice ; Animals ; T-Lymphocytes, Regulatory ; Porphyromonas gingivalis ; Gastrointestinal Microbiome ; Linoleic Acid/metabolism ; Mice, Inbred C57BL ; Colitis ; Inflammatory Bowel Diseases ; Periodontitis ; Inflammation/metabolism ; Th17 Cells
    Chemical Substances Linoleic Acid (9KJL21T0QJ)
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-45473-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Comparison of microbial composition and diversity in the upper respiratory tract between SARS-CoV-2 and influenza virus infections.

    Jia, Lijia / Xu, Meng / Hao, Mengchan / Liu, Di / Liu, Haizhou / Zheng, Xin / Chen, Jianjun

    Science China. Life sciences

    2022  Volume 65, Issue 7, Page(s) 1469–1472

    MeSH term(s) COVID-19 ; Humans ; Influenza, Human ; Middle East Respiratory Syndrome Coronavirus ; Orthomyxoviridae Infections ; Respiratory System ; Respiratory Tract Infections ; SARS-CoV-2
    Language English
    Publishing date 2022-03-24
    Publishing country China
    Document type Letter
    ZDB-ID 2546732-3
    ISSN 1869-1889 ; 1674-7305
    ISSN (online) 1869-1889
    ISSN 1674-7305
    DOI 10.1007/s11427-021-2092-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Study on Removal Mechanism for Copper Cyanide Complex Ions in Water

    Ying Liu / Baogang Sun / Wenting Jia / Yuan Wang / Lijia Huang / Pengge Ning / Shaojun Yuan

    International Journal of Molecular Sciences, Vol 24, Iss 5066, p

    Ion Species Differences and Evolution Process

    2023  Volume 5066

    Abstract: A large amount of cyanide-containing wastewater is discharged during electrode material synthesis. Among them, cyanides will form metal–cyanide complex ions which possess high stability, making it challenging to separate them from these wastewaters. ... ...

    Abstract A large amount of cyanide-containing wastewater is discharged during electrode material synthesis. Among them, cyanides will form metal–cyanide complex ions which possess high stability, making it challenging to separate them from these wastewaters. Therefore, it is imperative to understand the complexation mechanism of cyanide ions and heavy metal ions from wastewater in order to obtain a deep insight into the process of cyanide removal. This study employs Density Functional Theory (DFT) calculations to reveal the complexation mechanism of metal–cyanide complex ions formed by the interaction of Cu + and CN − in copper cyanide systems and its transformation patterns. Quantum chemical calculations show that the precipitation properties of Cu(CN) 4 3− can assist in the removal of CN − . Therefore, transferring other metal–cyanide complex ions to Cu(CN) 4 3− can achieve deep removal. OLI studio 11.0 analyzed the optimal process parameters of Cu(CN) 4 3− under different conditions and determined the optimal process parameters of the removal depth of CN − . This work has the potential to contribute to the future preparation of related materials such as CN − removal adsorbents and catalysts and provide theoretical foundations for the development of more efficient, stable, and environmentally friendly next-generation energy storage electrode materials.
    Keywords wastewater treatment ; ion species ; cyanide ; deep removal ; complexation mechanism ; cupric ion ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 333
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: γδT cells in oral tissue immune surveillance and pathology.

    Chen, Yilong / Du, Juan / Liu, Yitong / Luo, Zhenhua / Guo, Lijia / Xu, Junji / Jia, Lu / Liu, Yi

    Frontiers in immunology

    2023  Volume 13, Page(s) 1050030

    Abstract: The oral mucosa's immune system is composed of tissue-resident and specifically recruited leukocytes that could effectively tolerate a wide range of microbial and mechanical assaults. Shortly after ... ...

    Abstract The oral mucosa's immune system is composed of tissue-resident and specifically recruited leukocytes that could effectively tolerate a wide range of microbial and mechanical assaults. Shortly after CD4
    MeSH term(s) Humans ; Gingiva ; Immune System ; Interleukin-17 ; Periodontitis ; T-Lymphocyte Subsets/immunology ; Thymus Gland ; Immunologic Surveillance
    Chemical Substances Interleukin-17
    Language English
    Publishing date 2023-01-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.1050030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Non-targeted metabolomics identifies biomarkers in milk with high and low milk fat percentage.

    Feng, Xiaofang / Ma, Ruoshuang / Wang, Ying / Tong, Lijia / Wen, Wan / Mu, Tong / Tian, Jia / Yu, Baojun / Gu, Yaling / Zhang, Juan

    Food research international (Ottawa, Ont.)

    2024  Volume 179, Page(s) 113989

    Abstract: Milk is widely recognized as an important food source with health benefits. Different consumer groups have different requirements for the content and proportion of milk fat; therefore, it is necessary to investigate the differential metabolites and their ...

    Abstract Milk is widely recognized as an important food source with health benefits. Different consumer groups have different requirements for the content and proportion of milk fat; therefore, it is necessary to investigate the differential metabolites and their regulatory mechanisms in milk with high and low milk fat percentages (MFP). In this study, untargeted metabolomics was performed on milk samples from 13 cows with high milk fat percentage (HF) and 13 cows with low milk fat percentage (LF) using ultra-high performance liquid chromatography coupled with mass spectrometry (UHPLC-MS/MS). Forty-eight potential differentially labeled compounds were screened using the orthogonal partial least squares-discriminant analysis (OPLS-DA) combined with the weighted gene co-expression network analysis (WGCNA) method. Amino acid metabolism was the key metabolic pathway with significant enrichment of L-histidine, 5-oxoproline, L-aspartic acid, and L-glutamic acid. The negative correlation with MFP differentiated the HF and LF groups. To further determine the potential regulatory role of these amino acids on milk fat metabolism, the expression levels of marker genes in the milk fat synthesis pathway were explored. It was noticed that L-histidine reduced milk fat concentration primarily by inhibiting the triglycerides (TAG) synthesis pathway. L-aspartic acid and L-glutamic acid inhibited milk fat synthesis through the fatty acid de novo and TAG synthesis pathways. This study provides new insights into the mechanism underlying milk fat synthesis and milk quality improvement.
    MeSH term(s) Female ; Animals ; Cattle ; Milk/chemistry ; Tandem Mass Spectrometry ; Glutamic Acid/analysis ; Aspartic Acid/analysis ; Aspartic Acid/metabolism ; Histidine/analysis ; Histidine/metabolism ; Biomarkers/metabolism
    Chemical Substances Glutamic Acid (3KX376GY7L) ; Aspartic Acid (30KYC7MIAI) ; Histidine (4QD397987E) ; Biomarkers
    Language English
    Publishing date 2024-01-06
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2024.113989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Measuring the intensive care experience of intensive care unit patients: A cross-sectional study in western China.

    Hu, Aiping / Wang, Jia / Zhou, Qimin / Xu, Lijia / Yang, Shuang / Xiang, Mingfang / Wang, Guorong

    Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

    2023  Volume 37, Issue 1, Page(s) 111–119

    Abstract: Background: The negative experiences of intensive care unit (ICU) patients seriously affect their quality of life and survival outcomes. Thus, it is of great significance to evaluate the monitoring experience of ICU patients for the clinical improvement ...

    Abstract Background: The negative experiences of intensive care unit (ICU) patients seriously affect their quality of life and survival outcomes. Thus, it is of great significance to evaluate the monitoring experience of ICU patients for the clinical improvement of their experiences and promote interventions.
    Objectives: The objective of this study was to investigate patients' experiences of ICU and to understand the sources of patient experience and influencing factors.
    Methods: From November 2021 to September 2022, a cross-sectional survey was conducted with 600 inpatients from four grade A-III hospitals in western China. Data were collected using the Chinese version of the Intensive Care Experience Questionnaire.
    Results: 585 valid questionnaires were collected, the response rate was 97.5%. ICU patients in western China scored below-the-average for their intensive care experience. Family monthly income, occupation types, medical payment method, type of ICU, ICU admission plan, ICU admission times, mechanical ventilation use, fertility status, analgesia, sedation, and Acute Physiology and Chronic Health Evaluation II scores are important factors influencing ICU patients' intensive care experience.
    Conclusions: Medical staff need to pay attention to patient experience, improve the awareness of patient stressors and influencing factors, design nursing programs conducive to patient-positive experience, and promote interventions to further improve the long-term prognosis of patients. The results of this study can also be used as a set of nursing-sensitive indicators for evaluating nursing structure, process, and outcomes.
    MeSH term(s) Humans ; Cross-Sectional Studies ; Intensive Care Units ; Quality of Life ; Critical Care ; China
    Language English
    Publishing date 2023-12-11
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1159493-7
    ISSN 1878-1721 ; 1036-7314
    ISSN (online) 1878-1721
    ISSN 1036-7314
    DOI 10.1016/j.aucc.2023.09.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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