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  1. Book ; Online: Production of beneficial insects in the Ramacca Biofactory for Biocontrol in citrus fruits (BIOFRUITNET Video)

    Alföldi, Thomas / Verrastro, Vincenzo / D'Angelo, Dario / Strano, Antonio / Calcaterra, Salvatore

    2023  

    Abstract: The Ramacca Biofactory in Sicily breeds beneficial insects for citrus farming. This video presents some of the insects that are produced: The first is a parasitoid called Aphytis melinus. The second is a predator, a ladybird. It is called Cryptolaemus ... ...

    Abstract The Ramacca Biofactory in Sicily breeds beneficial insects for citrus farming. This video presents some of the insects that are produced: The first is a parasitoid called Aphytis melinus. The second is a predator, a ladybird. It is called Cryptolaemus montrouzieri. We will also look at the two species on which these two useful insects are bred (Aspidiotus nerii and Planococcus citri).
    Keywords Biodiversity and ecosystem services ; Fruit and berries ; Crop health ; quality ; protection
    Language Italian
    Publishing country dk
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Fasting duration impacts ribosome protein 6 phosphorylation in zebrafish brain: New insights in aquatic organisms' welfare.

    Raggio, Maria / Giaquinto, Daniela / Attanasio, Chiara / Palladino, Antonio / Esposito, Vincenzo / Radaelli, Giuseppe / De Felice, Elena / de Girolamo, Paolo / D'Angelo, Livia

    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft

    2024  Volume 254, Page(s) 152266

    Abstract: Background: Short- or mid-term fasting, full or partial, triggers metabolic response known to have in turn health effects in an organism. At central level, the metabolic stimulus triggered by fasting is known to be perceived firstly by hypothalamic ... ...

    Abstract Background: Short- or mid-term fasting, full or partial, triggers metabolic response known to have in turn health effects in an organism. At central level, the metabolic stimulus triggered by fasting is known to be perceived firstly by hypothalamic neurons. In the field of neuroscience, ribosomal protein S6 (S6) phosphorylation is commonly used as a readout of the mammalian target of rapamycin complex 1 signalling activation or as a marker for neuronal activity. The aim of this study is addressed to evaluate whether the phosphorylation of S6 occurs in the central neurons of zebrafish exposed to four (short-term) and seven (mid-term) days of complete fasting.
    Methods: Group-housed adult zebrafish were exposed to four and seven days of complete food withdrawal. At the end of the experimental period, Western blotting analyses were carried out to measure the expression levels of the phosphorylated S6 (pS6) by comparing the two experimental conditions versus the control group. The same antibody was then used to identify the distribution pattern of pS6 immunoreactive neurons in the whole brain and in the taste buds.
    Results: We did not observe increased pS6 levels expression in the brain of animals exposed to short-term fasting compared to the control, whereas the expression increased in brain homogenates of animals exposed to mid-term fasting. pS6 immunoreactivity was reported in some hypothalamic neurons, as well as in the dorsal area of telencephalon and preoptic area, a neurosecretory region homolog to the mammalian paraventricular nucleus. Remarkably, we observed pS6 immunostaining in the sensory cells of taste buds lining the oral epithelium.
    Conclusions: Taken together, our data show that in zebrafish, differently from other fish species, seven days of fasting triggers neuronal activity. Furthermore, the immunostaining on sensory cells of taste buds suggests that metabolic changes may modulate also peripheral sensory cells. This event may have valuable implications when using zebrafish to design metabolic studies involving fasting as well as practical consequences on the animal welfare, in particularly stressful conditions, such as transportation.
    Language English
    Publishing date 2024-04-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1106738-x
    ISSN 1618-0402 ; 0940-9602
    ISSN (online) 1618-0402
    ISSN 0940-9602
    DOI 10.1016/j.aanat.2024.152266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol-Gel Route.

    Blanco, Ignazio / Latteri, Alberta / Cicala, Gianluca / D'Angelo, Antonio / Viola, Veronica / Arconati, Vincenzo / Catauro, Michelina

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 3

    Abstract: This paper aims to synthesize, via the sol-gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt% ...

    Abstract This paper aims to synthesize, via the sol-gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transform-Infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Kirby-Bauer analyses were performed. FT-IR was used to evaluate the hybrid formation and the influence of both PEG and Quercetin in the hybrid synthesized materials, SEM was used to evaluate the morphological properties, while the Kirby-Bauer test was used to understand the ability of the materials to inhibit the growth of the assayed bacterial strains
    MeSH term(s) Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacteria/classification ; Bacteria/drug effects ; Biocompatible Materials/chemistry ; Microbial Sensitivity Tests ; Microscopy, Electron, Scanning ; Polyethylene Glycols/chemistry ; Quercetin/chemistry ; Silicon Dioxide/chemistry ; Spectroscopy, Fourier Transform Infrared
    Chemical Substances Anti-Bacterial Agents ; Biocompatible Materials ; Polyethylene Glycols (3WJQ0SDW1A) ; Silicon Dioxide (7631-86-9) ; Quercetin (9IKM0I5T1E)
    Language English
    Publishing date 2022-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27030979
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Oxidative Stress in Type 2 Diabetes: Impacts from Pathogenesis to Lifestyle Modifications.

    Caturano, Alfredo / D'Angelo, Margherita / Mormone, Andrea / Russo, Vincenzo / Mollica, Maria Pina / Salvatore, Teresa / Galiero, Raffaele / Rinaldi, Luca / Vetrano, Erica / Marfella, Raffaele / Monda, Marcellino / Giordano, Antonio / Sasso, Ferdinando Carlo

    Current issues in molecular biology

    2023  Volume 45, Issue 8, Page(s) 6651–6666

    Abstract: Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its associated complications. The imbalance between reactive oxygen species (ROS) production and the body's antioxidant defence mechanisms leads to cellular damage ... ...

    Abstract Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its associated complications. The imbalance between reactive oxygen species (ROS) production and the body's antioxidant defence mechanisms leads to cellular damage and dysfunction. In diabetes, chronic hyperglycaemia and mitochondrial dysfunction contribute to increased ROS production, further exacerbating oxidative stress. This oxidative burden adversely affects various aspects of diabetes, including impaired beta-cell function and insulin resistance, leading to disrupted glucose regulation. Additionally, oxidative stress-induced damage to blood vessels and impaired endothelial function contribute to the development of diabetic vascular complications such as retinopathy, nephropathy, and cardiovascular diseases. Moreover, organs and tissues throughout the body, including the kidneys, nerves, and eyes, are vulnerable to oxidative stress, resulting in diabetic nephropathy, neuropathy, and retinopathy. Strategies to mitigate oxidative stress in diabetes include antioxidant therapy, lifestyle modifications, and effective management of hyperglycaemia. However, further research is necessary to comprehensively understand the underlying mechanisms of oxidative stress in diabetes and to evaluate the efficacy of antioxidant interventions in preventing and treating diabetic complications. By addressing oxidative stress, it might be possible to alleviate the burden of diabetes and improve patient outcomes.
    Language English
    Publishing date 2023-08-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2000024-8
    ISSN 1467-3045 ; 1467-3037
    ISSN (online) 1467-3045
    ISSN 1467-3037
    DOI 10.3390/cimb45080420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route

    Ignazio Blanco / Alberta Latteri / Gianluca Cicala / Antonio D’Angelo / Veronica Viola / Vincenzo Arconati / Michelina Catauro

    Molecules, Vol 27, Iss 979, p

    2022  Volume 979

    Abstract: This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt% ...

    Abstract This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transform-Infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Kirby–Bauer analyses were performed. FT-IR was used to evaluate the hybrid formation and the influence of both PEG and Quercetin in the hybrid synthesized materials, SEM was used to evaluate the morphological properties, while the Kirby–Bauer test was used to understand the ability of the materials to inhibit the growth of the assayed bacterial strains (Escherichia coli , Pseudomonas aeruginosa , Enterococcus faecalis , and Staphylococcus aureus ).
    Keywords sol–gel method ; hybrids materials ; anti-bacterial properties ; FT-IR ; SEM ; Organic chemistry ; QD241-441
    Subject code 620 ; 540
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Aneurysm inside meningioma: an unusual association.

    De Bonis, Costanzo / Gazzeri, Roberto / Gorgoglione, Leonardo / d'Angelo, Vincenzo Antonio

    British journal of neurosurgery

    2019  Volume 37, Issue 3, Page(s) 294–295

    Abstract: The association of a meningioma and intratumoral aneurysm is extremely rare. The coexistence of both lesions may cause difficulties in diagnosis and treatment. We present the case of a 65 y.o. woman with a left temporal meningioma and an intralesional ... ...

    Abstract The association of a meningioma and intratumoral aneurysm is extremely rare. The coexistence of both lesions may cause difficulties in diagnosis and treatment. We present the case of a 65 y.o. woman with a left temporal meningioma and an intralesional ruptured aneurysm of a terminal branch of the middle cerebral artery whose parental vessel fed the tumor. The tumor and the embedded aneurysm were removed safely with improvement of her symptoms.
    MeSH term(s) Humans ; Female ; Meningioma/complications ; Meningioma/diagnostic imaging ; Meningioma/surgery ; Intracranial Aneurysm/complications ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Meningeal Neoplasms/complications ; Meningeal Neoplasms/diagnostic imaging ; Meningeal Neoplasms/surgery ; Aneurysm, Ruptured/complications ; Aneurysm, Ruptured/diagnostic imaging ; Aneurysm, Ruptured/surgery ; Middle Cerebral Artery
    Language English
    Publishing date 2019-11-28
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 639029-8
    ISSN 1360-046X ; 0268-8697
    ISSN (online) 1360-046X
    ISSN 0268-8697
    DOI 10.1080/02688697.2019.1694135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Validation in type 2 diabetes of a metabolomic signature of all-cause mortality.

    Copetti, Massimiliano / Baroni, Marco Giorgio / Buzzetti, Raffaella / Cavallo, Maria Gisella / Cossu, Efiso / D'Angelo, Paola / Cosmo, Salvatore De / Leonetti, Frida / Morano, Susanna / Morviducci, Lelio / Napoli, Nicola / Prudente, Sabrina / Pugliese, Giuseppe / Savino, Antonio Fernando / Trischitta, Vincenzo

    Diabetes/metabolism research and reviews

    2023  Volume 40, Issue 2, Page(s) e3734

    Abstract: Context: Mortality in type 2 diabetes is twice that of the normoglycemic population. Unravelling biomarkers that identify high-risk patients for referral to the most aggressive and costly prevention strategies is needed.: Objective: To validate in ... ...

    Abstract Context: Mortality in type 2 diabetes is twice that of the normoglycemic population. Unravelling biomarkers that identify high-risk patients for referral to the most aggressive and costly prevention strategies is needed.
    Objective: To validate in type 2 diabetes the association with all-cause mortality of a 14-metabolite score (14-MS) previously reported in the general population and whether this score can be used to improve well-established mortality prediction models.
    Methods: This is a sub-study consisting of 600 patients from the "Sapienza University Mortality and Morbidity Event Rate" (SUMMER) study in diabetes, a prospective multicentre investigation on all-cause mortality in patients with type 2 diabetes. Metabolic biomarkers were quantified from serum samples using high-throughput proton nuclear magnetic resonance metabolomics.
    Results: In type 2 diabetes, the 14-MS showed a significant (p < 0.0001) association with mortality, which was lower (p < 0.0001) than that reported in the general population. This difference was mainly due to two metabolites (histidine and ratio of polyunsaturated fatty acids to total fatty acids) with an effect size that was significantly (p = 0.01) lower in diabetes than in the general population. A parsimonious 12-MS (i.e. lacking the 2 metabolites mentioned above) improved patient discrimination and classification of two well-established mortality prediction models (p < 0.0001 for all measures).
    Conclusions: The metabolomic signature of mortality in the general population is only partially effective in type 2 diabetes. Prediction markers developed and validated in the general population must be revalidated if they are to be used in patients with diabetes.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2 ; Prospective Studies ; Metabolomics ; Biomarkers
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-10-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1470192-3
    ISSN 1520-7560 ; 1520-7552
    ISSN (online) 1520-7560
    ISSN 1520-7552
    DOI 10.1002/dmrr.3734
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An Internet of Things Solution for Smart Agriculture

    Gianfranco Gagliardi / Marco Lupia / Gianni Cario / Francesco Cicchello Gaccio / Vincenzo D’Angelo / Antonio Igor Maria Cosma / Alessandro Casavola

    Agronomy, Vol 11, Iss 2140, p

    2021  Volume 2140

    Abstract: ... information about the health of the production. In this paper, the results of the recently concluded R&D ...

    Abstract Over the last decade, the increased use of information and communication technology (ICT) in agriculture applications has led to the definition of the concept of precision farming or equivalently smart agriculture . In this respect, the latest progress in connectivity, automation, images analysis and artificial intelligence allow farmers to monitor all production phases and, due to the help of automatic procedures, determine better treatments for their farms. One of the main objectives of a smart agriculture system is to improve the yield of the field. From this point of view, the Internet of Things (IoT) paradigm plays a key role in precision farming applications due to the fact that the use of IoT sensors provides precise information about the health of the production. In this paper, the results of the recently concluded R&D project ENOTRIA TELLUS are reported. The project aimed at the development of all hardware/software components for implementing a precision farming architecture allowing the farmers to manage and monitor the vineyards’ health status. The smart architecture combines various sub-systems (web application, local controllers, unmanned aerial vehicles, multi-spectral cameras, weather sensors etc.) and electronic devices, each of them in charge of performing specific operations: remote data analysis, video processing for vegetation analysis, wireless data exchanges and weather and monitoring data evaluation. Two pilot sites were built where the smart architecture was tested and validated in real scenarios. Experimental activities show that the designed smart agriculture architecture allowed the farmers to properly schedule the various phases of cultivation and harvesting.
    Keywords precision farming ; smart agriculture ; agriculture 4.0 ; Internet of Things ; multi-spectral analysis ; ZigBee ; Agriculture ; S
    Subject code 720
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: New-Onset Atrial Fibrillation and Early Mortality Rate in COVID-19 Patients: Association with IL-6 Serum Levels and Respiratory Distress.

    Bagnato, Gianluca / Imbalzano, Egidio / Aragona, Caterina Oriana / Ioppolo, Carmelo / Di Micco, Pierpaolo / La Rosa, Daniela / Costa, Francesco / Micari, Antonio / Tomeo, Simona / Zirilli, Natalia / Sciacqua, Angela / D'Angelo, Tommaso / Cacciola, Irene / Bitto, Alessandra / Irrera, Natasha / Russo, Vincenzo / Roberts, William Neal / Gangemi, Sebastiano / Versace, Antonio Giovanni

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 4

    Abstract: Background and ... ...

    Abstract Background and objectives
    MeSH term(s) Atrial Fibrillation/epidemiology ; COVID-19/complications ; Dyspnea ; Female ; Humans ; Interleukin-6/blood ; Male ; Respiratory Distress Syndrome ; Retrospective Studies ; Risk Factors
    Chemical Substances IL6 protein, human ; Interleukin-6
    Language English
    Publishing date 2022-04-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58040530
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  10. Article: An Internet of Things Solution for Smart Agriculture

    Gagliardi, Gianfranco / Lupia, Marco / Cario, Gianni / Cicchello Gaccio, Francesco / D’Angelo, Vincenzo / Cosma, Antonio Igor Maria / Casavola, Alessandro

    Agronomy. 2021 Oct. 26, v. 11, no. 11

    2021  

    Abstract: ... information about the health of the production. In this paper, the results of the recently concluded R&D ...

    Abstract Over the last decade, the increased use of information and communication technology (ICT) in agriculture applications has led to the definition of the concept of precision farming or equivalently smart agriculture. In this respect, the latest progress in connectivity, automation, images analysis and artificial intelligence allow farmers to monitor all production phases and, due to the help of automatic procedures, determine better treatments for their farms. One of the main objectives of a smart agriculture system is to improve the yield of the field. From this point of view, the Internet of Things (IoT) paradigm plays a key role in precision farming applications due to the fact that the use of IoT sensors provides precise information about the health of the production. In this paper, the results of the recently concluded R&D project ENOTRIA TELLUS are reported. The project aimed at the development of all hardware/software components for implementing a precision farming architecture allowing the farmers to manage and monitor the vineyards’ health status. The smart architecture combines various sub-systems (web application, local controllers, unmanned aerial vehicles, multi-spectral cameras, weather sensors etc.) and electronic devices, each of them in charge of performing specific operations: remote data analysis, video processing for vegetation analysis, wireless data exchanges and weather and monitoring data evaluation. Two pilot sites were built where the smart architecture was tested and validated in real scenarios. Experimental activities show that the designed smart agriculture architecture allowed the farmers to properly schedule the various phases of cultivation and harvesting.
    Keywords Internet ; agronomy ; artificial intelligence ; automation ; communications technology ; computer software ; health status ; vegetation ; weather
    Language English
    Dates of publication 2021-1026
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2607043-1
    ISSN 2073-4395
    ISSN 2073-4395
    DOI 10.3390/agronomy11112140
    Database NAL-Catalogue (AGRICOLA)

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