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  1. Article ; Online: Editorial: Is vedolizumab the preferred biologic therapy for biologic-naïve patients with ulcerative colitis?

    Yamamoto, Takayuki

    Alimentary pharmacology & therapeutics

    2023  Volume 58, Issue 5, Page(s) 546–547

    MeSH term(s) Humans ; Colitis, Ulcerative/drug therapy ; Antibodies, Monoclonal, Humanized/therapeutic use ; Gastrointestinal Agents/therapeutic use ; Biological Products/therapeutic use
    Chemical Substances vedolizumab (9RV78Q2002) ; Antibodies, Monoclonal, Humanized ; Gastrointestinal Agents ; Biological Products
    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.17628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2206: Show issues Location:
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  2. Article ; Online: Next-generation Rechargeable Batteries Utilizing Ionic Liquids and Various Charge Carriers

    Takayuki YAMAMOTO

    Electrochemistry, Vol 90, Iss 10, Pp 101005-

    2022  Volume 101005

    Abstract: Renewable energy resources and rechargeable batteries are key to establishing a carbon-neutral society. Lithium-ion batteries (LIBs) have been widely used in portable electronic devices for the past 30 years. However, the further spread of large-scale ... ...

    Abstract Renewable energy resources and rechargeable batteries are key to establishing a carbon-neutral society. Lithium-ion batteries (LIBs) have been widely used in portable electronic devices for the past 30 years. However, the further spread of large-scale batteries is essential in the household and industrial sectors, which drives the research and development of technologies beyond LIBs. Since ionic liquids are safe and confer unique physicochemical properties, several next-generation batteries utilizing ionic liquid electrolytes have been researched. Sodium-ion and potassium-ion batteries show promise in overcoming the potential problems of LIBs related to the uneven distribution of lithium and cobalt resources. Fluoride-shuttle batteries deliver significantly higher theoretical energy densities compared to current LIBs. Nevertheless, many issues remain unresolved for the practical application of these batteries. This comprehensive paper provides several research topics on next-generation rechargeable batteries utilizing ionic liquids and various charge carriers, unveiling their novelty, the issues to be solved, and future research directions.
    Keywords ionic liquids ; sodium-ion batteries ; potassium-ion batteries ; fluoride-shuttle batteries ; Technology ; T ; Physical and theoretical chemistry ; QD450-801
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher The Electrochemical Society of Japan
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Nutrition and diet in inflammatory bowel disease.

    Yamamoto, Takayuki / Shimoyama, Takahiro

    Current opinion in gastroenterology

    2023  Volume 39, Issue 2, Page(s) 110–114

    Abstract: Purpose of review: This study was to review the current evidence for dietary risk factors for developing inflammatory bowel disease (IBD), and therapeutic benefit of dietary and enteral interventions in IBD.: Recent findings: A Westernized diet rich ... ...

    Abstract Purpose of review: This study was to review the current evidence for dietary risk factors for developing inflammatory bowel disease (IBD), and therapeutic benefit of dietary and enteral interventions in IBD.
    Recent findings: A Westernized diet rich in protein, fats and refined carbohydrates and low in fibre, fruits and vegetables may increase risk of developing IBD. Nevertheless, there are methodological limitations in case-control studies, which can affect the accuracy of the outcomes. Currently, various dietary interventions and supplements have been attempted to control the disease activity of IBD, but none of them showed striking efficacy. Exclusive enteral nutrition (EEN) is recommended as the first-line therapy in paediatric patients with active Crohn's disease. EEN is recommended in adults with good adherence to enteral formula and with intolerance to corticosteroids. Partial enteral nutrition is not recommended as primary therapy for the maintenance of remission, but it is used when undernutrition cannot be treated sufficiently with diets.
    Summary: Dietary risk factors for IBD, and the efficacies of dietary and enteral interventions need to be confirmed by large, well designed studies.
    MeSH term(s) Humans ; Child ; Remission Induction ; Inflammatory Bowel Diseases/therapy ; Crohn Disease/therapy ; Diet ; Dietary Supplements
    Language English
    Publishing date 2023-01-03
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 632571-3
    ISSN 1531-7056 ; 0267-1379
    ISSN (online) 1531-7056
    ISSN 0267-1379
    DOI 10.1097/MOG.0000000000000905
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    Zs.A 2072: Show issues Location:
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  4. Article ; Online: Amide-Based Ionic Liquid Electrolytes for Alkali-Metal-Ion Rechargeable Batteries.

    Yamamoto, Takayuki / Nohira, Toshiyuki

    Chemical record (New York, N.Y.)

    2023  Volume 23, Issue 8, Page(s) e202300169

    Abstract: Ionic liquids (ILs) have a wide variety of applications in energy storage and material production. ILs are composed of only cations and anions, without any molecular solvents, and are generally known as "designer liquids (solvents)" because their ... ...

    Abstract Ionic liquids (ILs) have a wide variety of applications in energy storage and material production. ILs are composed of only cations and anions, without any molecular solvents, and are generally known as "designer liquids (solvents)" because their physicochemical properties can be tuned by the combination of ionic species. In recent several decades, research and development activities of rechargeable batteries have garnered considerable attention because certain groups of ILs exhibit high electrochemical stability and moderate ionic conductivity, rendering them suitable for application in high-voltage batteries. ILs with amide anions are representative electrolytes and are extensively researched by many research groups, including our group. This paper focuses on amide-based ILs as electrolytes for alkali-metal-ion rechargeable batteries, introducing their history, characteristics, and existing challenges to be addressed.
    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2044646-9
    ISSN 1528-0691 ; 1527-8999
    ISSN (online) 1528-0691
    ISSN 1527-8999
    DOI 10.1002/tcr.202300169
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  5. Article ; Online: Longitudinal Stent Elongation Due to Inappropriate Post-Dilatation　- Insight From a Bench Test.

    Yamamoto, Hiroyuki / Nakano, Shinsuke / Saito, Takayuki / Takaya, Tomofumi

    Circulation reports

    2023  Volume 5, Issue 5, Page(s) 227–228

    Language English
    Publishing date 2023-04-04
    Publishing country Japan
    Document type Journal Article
    ISSN 2434-0790
    ISSN (online) 2434-0790
    DOI 10.1253/circrep.CR-23-0026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Editorial comment: "Diffuse glioma, not otherwise specified: imaging-based risk stratification achieves histomolecular-level prognostication".

    Yamamoto, Takayuki / Tourdias, Thomas

    European radiology

    2022  Volume 32, Issue 11, Page(s) 7778–7779

    MeSH term(s) Humans ; Glioma/diagnostic imaging ; Isocitrate Dehydrogenase ; Risk Assessment
    Chemical Substances Isocitrate Dehydrogenase (EC 1.1.1.41)
    Language English
    Publishing date 2022-09-13
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-022-09098-3
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    Zs.A 3300: Show issues Location:
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  7. Article: Fecal Diversion in Complex Perianal Fistulizing Crohn's Disease.

    Yamamoto, Takayuki / Shimoyama, Takahiro

    Clinics in colon and rectal surgery

    2022  Volume 35, Issue 1, Page(s) 5–9

    Abstract: Complex perianal Crohn's disease (CD) remains a challenging problem. Fecal stream is thought to be a trigger of disease progression in patients with CD. In patients with refractory perianal CD, diversion of fecal stream is sometimes required to alleviate ...

    Abstract Complex perianal Crohn's disease (CD) remains a challenging problem. Fecal stream is thought to be a trigger of disease progression in patients with CD. In patients with refractory perianal CD, diversion of fecal stream is sometimes required to alleviate clinical symptoms when medical and local surgical management are unsuccessful. Several studies evaluated the outcomes of fecal diversion for complex perianal CD. After fecal diversion, the majority of patients achieved early clinical response, but the prospect of restoring bowel continuity was low (approximately 20%). Nearly half of the patients eventually required proctectomy. A number of studies attempted to identify predictive factors for the outcomes of fecal diversion. Only rectal involvement was associated with unsuccessful restoration of bowel continuity. Biologic therapy did not seem to improve the efficacy of fecal diversion, although the evidence level was low because of insufficient data or methodological limitations. Based on these results, fecal diversion may be useful in alleviating clinical symptoms related to severe perianal CD and avoiding immediate proctectomy. The impact of biologic therapy on the outcomes of fecal diversion should be further investigated.
    Language English
    Publishing date 2022-01-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2048635-2
    ISSN 1531-0043
    ISSN 1531-0043
    DOI 10.1055/s-0041-1740028
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    Zs.A 3931: Show issues Location:
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  8. Article: Smartphone-Enabled Web-Based Simulation of Cellular Neurophysiology for Laboratory Course and its Effectiveness.

    Yamamoto, Takayuki / Weitemier, Adam / Kurokawa, Makoto

    Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience

    2023  Volume 21, Issue 2, Page(s) A151–A158

    Abstract: The introduction of computer simulations has enhanced the teaching of neurobiology. Many simulators for personal computers are available, but in countries where schools have low school information and communication technology readiness, it is difficult ... ...

    Abstract The introduction of computer simulations has enhanced the teaching of neurobiology. Many simulators for personal computers are available, but in countries where schools have low school information and communication technology readiness, it is difficult to introduce computer simulations. Even in such countries, however, students often have their own smartphones and are good at operating them. Therefore, we have developed five web-based simulators that cover a wide range of neurophysiology, including single and whole-cell channel currents, membrane potentials and generation and conduction of action potentials using HTML5 and JavaScript. These simulators may be run free of charge on any device, regardless of the model or OS, thereby enabling schools that have no experience in introducing simulations to introduce them easily. These simulators were especially useful in many schools during COVID-19 restrictions. In this paper, we explain the functions of the simulators we have developed and introduce some practical examples. To verify the usefulness of the simulators, we also conducted a survey in the classrooms in which the simulators were used. Understanding and motivation to learn was shown to increase significantly, indicating that these are useful for neurobiology education.
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2577251-X
    ISSN 1544-2896
    ISSN 1544-2896
    DOI 10.59390/RCVF6232
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  9. Article ; Online: The cAMP signaling module regulates sperm motility in the liverwort

    Yamamoto, Chiaki / Takahashi, Fumio / Suetsugu, Noriyuki / Yamada, Kazumasa / Yoshikawa, Shinya / Kohchi, Takayuki / Kasahara, Masahiro

    Proceedings of the National Academy of Sciences of the United States of America

    2024  Volume 121, Issue 16, Page(s) e2322211121

    Abstract: Adenosine 3',5'-cyclic monophosphate (cAMP) is a universal signaling molecule that acts as a second messenger in various organisms. It is well established that cAMP plays essential roles across the tree of life, although the function of cAMP in land ... ...

    Abstract Adenosine 3',5'-cyclic monophosphate (cAMP) is a universal signaling molecule that acts as a second messenger in various organisms. It is well established that cAMP plays essential roles across the tree of life, although the function of cAMP in land plants has long been debated. We previously identified the enzyme with both adenylyl cyclase (AC) and cAMP phosphodiesterase (PDE) activity as the cAMP-synthesis/hydrolysis enzyme COMBINED AC with PDE (CAPE) in the liverwort
    MeSH term(s) Male ; Animals ; Marchantia/genetics ; Cyclic AMP/metabolism ; Sperm Motility/genetics ; Seeds/metabolism ; Adenylyl Cyclases/metabolism ; Spermatozoa/metabolism
    Chemical Substances Cyclic AMP (E0399OZS9N) ; Adenylyl Cyclases (EC 4.6.1.1)
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2322211121
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  10. Article ; Online: Concomitant distal bare-metal stenting for residual true lumen stenosis in a frozen elephant trunk technique for acute type A aortic dissection.

    Yamamoto, Hiroshi / Kadohama, Takayuki / Takagi, Daichi / Wada, Takuya

    JTCVS techniques

    2022  Volume 15, Page(s) 27–30

    Language English
    Publishing date 2022-08-18
    Publishing country United States
    Document type Journal Article
    ISSN 2666-2507
    ISSN (online) 2666-2507
    DOI 10.1016/j.xjtc.2022.08.010
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