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Article ; Online: Intracardiac Migration of the Ureteral Double-J Stent during Percutaneous Nephrolithotomy

Chun-Kai Chang / Yi-Hsuan Wu / Ming-Chen Paul Shih / Jiun-Hung Geng

Medicina, Vol 57, Iss 939, p

2021 Volume 939

Abstract: The complications of percutaneous nephrolithotomy (PNL) include hemorrhage, damage to adjuvant organs, and other medical issues, although intracardiac migration of ureteral double-J stent has never been found during PNL and delaying the diagnosis might ... ...

Abstract	The complications of percutaneous nephrolithotomy (PNL) include hemorrhage, damage to adjuvant organs, and other medical issues, although intracardiac migration of ureteral double-J stent has never been found during PNL and delaying the diagnosis might cause mortality. We report the case of a 60-year-old male who was admitted to receive one-stage PNL for right renal stones. During operation, an unexpected atrial fibrillation with a drop in blood pressure was suddenly encountered and the chest X-ray subsequently showed that the ureteral double-J had penetrated deep into the heart. Emergent endovascular intervention was performed to remove the stent and the patient was uneventfully discharged 2 days later.
Keywords	complication ; intracardiac migration ; ureteral double-J stent ; nephrolithiasis ; percutaneous nephrolithotomy ; Medicine (General) ; R5-920
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Intracardiac Migration of the Ureteral Double-J Stent during Percutaneous Nephrolithotomy.

Chang, Chun-Kai / Wu, Yi-Hsuan / Shih, Ming-Chen Paul / Geng, Jiun-Hung

Medicina (Kaunas, Lithuania)

2021 Volume 57, Issue 9

Abstract	The complications of percutaneous nephrolithotomy (PNL) include hemorrhage, damage to adjuvant organs, and other medical issues, although intracardiac migration of ureteral double-J stent has never been found during PNL and delaying the diagnosis might cause mortality. We report the case of a 60-year-old male who was admitted to receive one-stage PNL for right renal stones. During operation, an unexpected atrial fibrillation with a drop in blood pressure was suddenly encountered and the chest X-ray subsequently showed that the ureteral double-J had penetrated deep into the heart. Emergent endovascular intervention was performed to remove the stent and the patient was uneventfully discharged 2 days later.
MeSH term(s)	Humans ; Kidney Calculi/diagnostic imaging ; Kidney Calculi/surgery ; Male ; Middle Aged ; Nephrolithotomy, Percutaneous/adverse effects ; Nephrostomy, Percutaneous ; Stents/adverse effects ; Ureter/diagnostic imaging ; Ureter/surgery
Language	English
Publishing date	2021-09-06
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina57090939
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Article ; Online: Efficacy of transarterial chemoembolization with drug-eluting beads combined with systemic chemotherapy and targeted therapy in colorectal cancer liver metastasis.

Chen, Yen-Cheng / Huang, Ching-Wen / Li, Ching-Chun / Chang, Tsung-Kun / Su, Wei-Chih / Chen, Po-Jung / Yeh, Yung-Sung / Chang, Yu-Tang / Tsai, Hsiang-Lin / Shih, Ming-Chen Paul / Wang, Jaw-Yuan

World journal of surgical oncology

2023 Volume 21, Issue 1, Page(s) 378

Abstract: Background: Systemic therapy is the standard treatment for unresectable colorectal cancer with liver metastasis (CRCLM). Transarterial chemoembolization with drug-eluting beads (DEB-TACE) is considered an effective treatment option for CRCLM. Few ... ...

Abstract	Background: Systemic therapy is the standard treatment for unresectable colorectal cancer with liver metastasis (CRCLM). Transarterial chemoembolization with drug-eluting beads (DEB-TACE) is considered an effective treatment option for CRCLM. Few studies have investigated the combination of DEB-TACE, chemotherapy, and targeted therapy for CRCLM. In the present study, we evaluated the disease control rate (DCR), adverse events, and survival among patients with CRCLM who underwent the combination of DEB-TACE and chemotherapy/targeted therapy. Materials: We retrospectively reviewed 35 patients with CRCLM who were treated between January 2015 and January 2021. Standard systemic chemotherapy, targeted therapy, and 66 DEB-TACE procedures were administered. Data were collected on each DEB-TACE procedure, including chemotherapy agents, tumor burden of liver metastasis, number of DEB-TACE courses, and adverse events. Patients who received DEB-TACE after failure of first-line systemic therapy were categorized into the first-line failure group. Patients who received DEB-TACE after the failure of second-line, third-line, or fourth-line therapy were categorized into the other group. Subgroup analysis was performed to compare overall survival (OS) and progression-free survival (PFS) between the two groups. Results: In total, 35 patients with CRCLM (34 patients with adenocarcinoma and 1 patient with neuroendocrine carcinoma) were enrolled. In total, 13 patients (37.1%) had extrahepatic metastases at initial diagnosis. In this study, 66 DEB-TACE procedures were performed. The DCR was 54.3%. The median OS period was 47.4 months, and the estimated 3-year OS rate was 59.5%. The median PFS period was 6.3 months, and the estimated 1-year PFS rate was 20.6%. The PFS period was longer in the first-line failure group than in the other group (7.2 vs. 6.3 months). No significant difference was observed in OS between the two groups. Four episodes (6.1%) of grade 3 intra-abdominal infection were observed. Conclusion: The combination of chemotherapy, targeted therapy, and DEB-TACE can lead to a favorable DCR and survival outcomes in patients with CRCLM. Early intervention with DEB-TACE (i.e., after the failure of first-line therapy) has the potential to extend the PFS period in patients with CRCLM. Severe adverse events were rare and manageable. Further prospective, randomized controlled studies are warranted to obtain more conclusive findings.
MeSH term(s)	Humans ; Liver Neoplasms/pathology ; Carcinoma, Hepatocellular/pathology ; Retrospective Studies ; Chemoembolization, Therapeutic/methods ; Treatment Outcome ; Colorectal Neoplasms/pathology
Language	English
Publishing date	2023-12-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2118383-1
ISSN	1477-7819 ; 1477-7819
ISSN (online)	1477-7819
ISSN	1477-7819
DOI	10.1186/s12957-023-03253-w
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Article ; Online: Impact of cachexia on oncologic outcomes of sarcopenic patients with upper tract urothelial carcinoma after radical nephroureterectomy.

Hao-Wei Chen / Yu-Chen Chen / Li-Hwa Yang / Ming-Chen Paul Shih / Ching-Chia Li / Kuang-Shun Chueh / Wen-Jeng Wu / Yung-Shun Juan

PLoS ONE, Vol 16, Iss 4, p e

2021 Volume 0250033

Abstract: Objectives To investigate the prognostic significance of sarcopenic cachexia compared to sarcopenia without cachexia in the outcomes of upper urinary tract urothelial carcinoma (UTUC) patients treated with radical nephroureterectomy (RNU). Materials and ... ...

Abstract	Objectives To investigate the prognostic significance of sarcopenic cachexia compared to sarcopenia without cachexia in the outcomes of upper urinary tract urothelial carcinoma (UTUC) patients treated with radical nephroureterectomy (RNU). Materials and methods Between 2011 and 2016, 163 patients with UTUC who received RNU at a tertiary medical center were included. Pre-operatively clinical data, history, and abdominal computer tomography scans were analyzed retrospectively. The diagnosis of sarcopenia was based on abdominal computed tomography data on the patient's skeletal muscles. Outcomes of relapse-free, cancer-specific, and overall survival were analyzed by multivariate Cox regression. Results After adjusting for age, sex, pre-operatively estimated glomerular filtration rate, body mass index, underlying diseases, tumor grade, and tumor stage, cachexia was a significant poor prognostic factor for relapse-free survival (hazard ratio [HR]: 18.5, 95% confidence interval [CI]: 2.87-118, p = 0.002) and cancer-specific survival (HR: 26.6, 95% CI: 4.04-175, p = 0.001). In contrast, sarcopenia without cachexia was not a significant predictor of cancer outcomes. Conclusions To date, this is the first study to investigate the effect of cachexia among sarcopenic patients with UTUC treated with RNU. We identified the prognostic significance of cachexia on outcomes. Indeed, when UTUC is treated with RNU, we should evaluate not only sarcopenia status but also cachexia. The low survival rate among patients with UTUC complicated with cachexia deserves attention.
Keywords	Medicine ; R ; Science ; Q
Subject code	616 ; 610
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of cachexia on oncologic outcomes of sarcopenic patients with upper tract urothelial carcinoma after radical nephroureterectomy.

Chen, Hao-Wei / Chen, Yu-Chen / Yang, Li-Hwa / Shih, Ming-Chen Paul / Li, Ching-Chia / Chueh, Kuang-Shun / Wu, Wen-Jeng / Juan, Yung-Shun

PloS one

2021 Volume 16, Issue 4, Page(s) e0250033

Abstract: Objectives: To investigate the prognostic significance of sarcopenic cachexia compared to sarcopenia without cachexia in the outcomes of upper urinary tract urothelial carcinoma (UTUC) patients treated with radical nephroureterectomy (RNU).: Materials ...

Abstract	Objectives: To investigate the prognostic significance of sarcopenic cachexia compared to sarcopenia without cachexia in the outcomes of upper urinary tract urothelial carcinoma (UTUC) patients treated with radical nephroureterectomy (RNU). Materials and methods: Between 2011 and 2016, 163 patients with UTUC who received RNU at a tertiary medical center were included. Pre-operatively clinical data, history, and abdominal computer tomography scans were analyzed retrospectively. The diagnosis of sarcopenia was based on abdominal computed tomography data on the patient's skeletal muscles. Outcomes of relapse-free, cancer-specific, and overall survival were analyzed by multivariate Cox regression. Results: After adjusting for age, sex, pre-operatively estimated glomerular filtration rate, body mass index, underlying diseases, tumor grade, and tumor stage, cachexia was a significant poor prognostic factor for relapse-free survival (hazard ratio [HR]: 18.5, 95% confidence interval [CI]: 2.87-118, p = 0.002) and cancer-specific survival (HR: 26.6, 95% CI: 4.04-175, p = 0.001). In contrast, sarcopenia without cachexia was not a significant predictor of cancer outcomes. Conclusions: To date, this is the first study to investigate the effect of cachexia among sarcopenic patients with UTUC treated with RNU. We identified the prognostic significance of cachexia on outcomes. Indeed, when UTUC is treated with RNU, we should evaluate not only sarcopenia status but also cachexia. The low survival rate among patients with UTUC complicated with cachexia deserves attention.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Cachexia/mortality ; Cachexia/pathology ; Female ; Humans ; Male ; Middle Aged ; Nephroureterectomy/methods ; Prognosis ; Retrospective Studies ; Sarcopenia/mortality ; Sarcopenia/pathology ; Survival Rate ; Ureter/pathology ; Ureteral Neoplasms/mortality ; Ureteral Neoplasms/pathology
Language	English
Publishing date	2021-04-21
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0250033
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Recognition of supraduodenal artery from hepatic artery is essential to avoid untoward complications at HAIC: two cases.

Ou, Tzu-Hao / Wu, Ding-Kwo / Shih, Paul Ming-Chen / Chao, Min-Fang

BMJ case reports

2018 Volume 2018

MeSH term(s)	Carcinoma, Hepatocellular/blood supply ; Carcinoma, Hepatocellular/drug therapy ; Chemotherapy, Cancer, Regional Perfusion/adverse effects ; Chemotherapy, Cancer, Regional Perfusion/methods ; Duodenum/blood supply ; Hepatic Artery/abnormalities ; Humans ; Infusions, Intra-Arterial/adverse effects ; Infusions, Intra-Arterial/methods ; Liver Neoplasms/blood supply ; Liver Neoplasms/drug therapy ; Male ; Middle Aged ; Vascular Malformations/pathology
Language	English
Publishing date	2018-04-19
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2017-223627
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Article ; Online: Management of large ureteral stone with severe ureteral tortuosity: A novel technique of "straightening" against the tortuous ureter using simultaneous supine percutaneous nephrolithotomy and retrograde semirigid ureterolithotripsy.

Chen, Yu-Chen / Chen, Hao-Wei / Lo, Ing-Shiang / Li, Ching-Chia / Shih, Paul Ming-Chen / Huang, Tsung-Yi

International journal of urology : official journal of the Japanese Urological Association

2018 Volume 25, Issue 10, Page(s) 896–897

MeSH term(s)	Aged ; Combined Modality Therapy/methods ; Feasibility Studies ; Female ; Humans ; Lithotripsy/instrumentation ; Lithotripsy/methods ; Male ; Middle Aged ; Nephrolithotomy, Percutaneous/methods ; Patient Positioning/methods ; Supine Position ; Taiwan ; Tomography, X-Ray Computed ; Treatment Outcome ; Ureter/diagnostic imaging ; Ureter/surgery ; Ureteral Calculi/diagnostic imaging ; Ureteral Calculi/surgery ; Ureteroscopy/instrumentation ; Ureteroscopy/methods
Language	English
Publishing date	2018-07-01
Publishing country	Australia
Document type	Journal Article
ZDB-ID	1328401-0
ISSN	1442-2042 ; 0919-8172
ISSN (online)	1442-2042
ISSN	0919-8172
DOI	10.1111/iju.13733
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Article ; Online: Progression of Aortic Arch Calcification Is Associated with Overall and Cardiovascular Mortality in Hemodialysis.

Chung, Wei-Shiuan / Shih, Ming-Chen Paul / Wu, Pei-Yu / Huang, Jiun-Chi / Chen, Szu-Chia / Chiu, Yi-Wen / Chang, Jer-Ming / Chen, Hung-Chun

Disease markers

2020 Volume 2020, Page(s) 6293185

Abstract: Background: Vascular calcification is common and associated with unfavorable outcomes among patients with end-stage renal disease (ESRD). Nevertheless, little is known whether the progression of vascular calcification outweighs the baseline ... ...

Abstract	Background: Vascular calcification is common and associated with unfavorable outcomes among patients with end-stage renal disease (ESRD). Nevertheless, little is known whether the progression of vascular calcification outweighs the baseline calcification in association with overall and cardiovascular (CV) mortality in hemodialysis (HD) patients. Methods: This study included 140 maintenance HD patients. Vascular calcification was assessed using the aortic arch calcification (AoAC) score measured from chest radiographs at the baseline and the second year of follow-up. Progression of vascular calcification ( Results: During the mean follow-up period of 5.8 years, there were 49 (35%) overall mortality and 27 (19.3%) CV mortality. High brachial-ankle pulse wave velocity was positively correlated with Conclusion: Progression of AoAC outperformed the baseline AoAC in association with increased risk of overall and CV mortality in HD patients. A regular follow-up of chest radiograph and AoAC score assessments are simple and cost-effective to identify the high-risk individuals of unfavorable outcomes in maintenance HD patients.
MeSH term(s)	Adult ; Aged ; Ankle Brachial Index ; Aorta, Thoracic/physiopathology ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/mortality ; Female ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/mortality ; Kidney Failure, Chronic/therapy ; Linear Models ; Male ; Middle Aged ; Prospective Studies ; Pulse Wave Analysis ; Renal Dialysis/mortality ; Vascular Calcification/etiology
Language	English
Publishing date	2020-06-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	604951-5
ISSN	1875-8630 ; 0278-0240
ISSN (online)	1875-8630
ISSN	0278-0240
DOI	10.1155/2020/6293185
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Zs.A 1856: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Progression of Aortic Arch Calcification Is Associated with Overall and Cardiovascular Mortality in Hemodialysis

Wei-Shiuan Chung / Ming-Chen Paul Shih / Pei-Yu Wu / Jiun-Chi Huang / Szu-Chia Chen / Yi-Wen Chiu / Jer-Ming Chang / Hung-Chun Chen

Disease Markers, Vol

2020 Volume 2020

Abstract: Background. Vascular calcification is common and associated with unfavorable outcomes among patients with end-stage renal disease (ESRD). Nevertheless, little is known whether the progression of vascular calcification outweighs the baseline calcification ...

Abstract	Background. Vascular calcification is common and associated with unfavorable outcomes among patients with end-stage renal disease (ESRD). Nevertheless, little is known whether the progression of vascular calcification outweighs the baseline calcification in association with overall and cardiovascular (CV) mortality in hemodialysis (HD) patients. Methods. This study included 140 maintenance HD patients. Vascular calcification was assessed using the aortic arch calcification (AoAC) score measured from chest radiographs at the baseline and the second year of follow-up. Progression of vascular calcification (ΔAoAC) was defined as the difference between the two measurements of AoAC. The association of ΔAoAC with overall and CV mortality was evaluated using multivariate Cox regression analysis. Results. During the mean follow-up period of 5.8 years, there were 49 (35%) overall mortality and 27 (19.3%) CV mortality. High brachial-ankle pulse wave velocity was positively correlated with ΔAoAC, whereas old age was negatively correlated with ΔAoAC. In multivariate adjusted Cox analysis, increased ΔAoAC (per 1 unit), but not baseline AoAC, was significantly associated with overall mortality (HR, 1.183; 95% CI, 1.056–1.327; p=0.004) and CV mortality (HR, 1.194; 95% CI, 1.019–1.398; p=0.028). Conclusion. Progression of AoAC outperformed the baseline AoAC in association with increased risk of overall and CV mortality in HD patients. A regular follow-up of chest radiograph and AoAC score assessments are simple and cost-effective to identify the high-risk individuals of unfavorable outcomes in maintenance HD patients.
Keywords	Medicine (General) ; R5-920
Subject code	310 ; 616
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effect of preoperative computed tomography parameters and obesity on surgical outcomes of laparoendoscopic single-site adrenalectomy.

Chen, Yu-Chen / Lee, Hsiang-Ying / Shih, Ming-Chen Paul / Juan, Yung-Shun / Chen, Hao-Wei / Wu, Wen-Jeng / Wang, Yu-Tsang / Li, Ching-Chia

Surgical endoscopy

2019 Volume 34, Issue 11, Page(s) 4781–4787

Abstract: Background: The aims of the present study were to (1) analyse preoperative computed tomography (CT) parameters, (2) investigate whether obesity and CT parameters affect surgical outcomes in patients undergoing LESS lateral retroperitoneal adrenalectomy, ...

Abstract	Background: The aims of the present study were to (1) analyse preoperative computed tomography (CT) parameters, (2) investigate whether obesity and CT parameters affect surgical outcomes in patients undergoing LESS lateral retroperitoneal adrenalectomy, and (3) further establish the optimal cutoff point of CT parameters for tolerable operating time. Methods: Between January 2010 and August 2016, patients who underwent LESS adrenalectomy through the retroperitoneal approach in our hospitals were included. Patients' demographic data, preoperatively measured CT parameters (the depth and horizontal width to the adrenal gland in the axial view of abdominal CT, the vertical height in the coronal view of CT, and the angle of the depth and horizontal width), and intraoperative (operative time and blood loss) and postoperative (hospital stay and complications) parameters were retrospectively reviewed. Linear regression was performed to determine factors that potentially affect surgical outcomes. Results: In 116 patients, depth was the only CT parameter associated with surgical outcomes. Large depth (P = 0.005; 95% CI 1.739-9.256) and high BMI (P = 0.012; 95% CI 0.357-2.851) were factors significantly associated with longer operative time. The area under the ROC curve for the depth was 0.69 (P = 0.002), and the cutoff point 10.48 cm may be the tolerable operating time. Conclusions: Our results suggest a depth limit of 10.48 cm for the optimal prediction of operating time less than 90 min; although obese patients and deeper adrenal glands had longer operative time, LESS adrenalectomy could be performed in the obese patients without increased blood loss, prolonged hospital stay, or increased pain.
MeSH term(s)	Adrenal Gland Neoplasms/diagnosis ; Adrenal Gland Neoplasms/surgery ; Adrenal Glands/diagnostic imaging ; Adrenal Glands/surgery ; Adrenalectomy/methods ; Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Laparoscopy/methods ; Length of Stay ; Male ; Middle Aged ; Operative Time ; Preoperative Period ; Prognosis ; ROC Curve ; Retrospective Studies ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2019-12-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639039-0
ISSN	1432-2218 ; 0930-2794
ISSN (online)	1432-2218
ISSN	0930-2794
DOI	10.1007/s00464-019-07254-3
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