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  1. Article ; Online: Comparison of Photo-optical Transcutaneous Oxygen Tension Measurement with Electro-chemical Transcutaneous Oxygen Tension Measurement in Patients with Arterial Claudication.

    Leenstra, Bernard Simon / Kuppens, Geoffrey Zinu Lukas / van Bergen, Annette / de Kleijn, Robert / de Borst, Gert J / Verhoeven, Bart

    Annals of vascular surgery

    2021  Volume 77, Page(s) 274–279

    Abstract: Purpose: Photo-optical TCpO2 (pTCpO2) has been proposed as a new method to determine the partial oxygen pressure of the lower extremity in patients with peripheral arterial disease. It is aimed to determine the level of agreement between pTCpO2 and the ... ...

    Abstract Purpose: Photo-optical TCpO2 (pTCpO2) has been proposed as a new method to determine the partial oxygen pressure of the lower extremity in patients with peripheral arterial disease. It is aimed to determine the level of agreement between pTCpO2 and the traditional electro-chemical transcutaneous oxygen tension measurement (eTCpO2).
    Methods: Eighteen patients with intermittent claudication underwent simultaneous ankle-brachial index measurement, toe-pressure, pTCpO2 and eTCpO2 tests. Oxygen tension levels were measured on anterior chest and calf prior in rest (T0), during induced ischemia (T1) and after blood flow restoration (T2). TCpO2 agreement was assessed according to the principles of Bland and Altman.
    Results: Absolute average TCpO2 values differed between eTCpO2 and pTCpO2 for calf in T2 (38,1 mmHg (σ 14,4) vs. 49,8 (σ 22.3) with P = 0.35). The Bland-Altman plots demonstrated eTCpO2 and pTCpO2 bias of 3,7 mmHg (σ 18,8), 11,6 mmHg (σ 17,6) and 6,7 mmHg (σ 23,5) for T0, T1 and T2 for the calf.
    Conclusion: pTCpO2 is in agreement with eTCpO2 in measuring pO2 levels of the lower extremity in rest and during induced ischemia in patients with vascular claudication. The large variability between eTCpO2 and pTCpO2 should be accounted for, while pTCpO2 values have a tendency to demonstrate higher values in comparison to eTCpO2.
    MeSH term(s) Aged ; Biomarkers/blood ; Blood Gas Monitoring, Transcutaneous ; Electrochemical Techniques ; Exercise Test ; Feasibility Studies ; Female ; Humans ; Intermittent Claudication/blood ; Intermittent Claudication/diagnosis ; Intermittent Claudication/physiopathology ; Male ; Middle Aged ; Oxygen/blood ; Peripheral Arterial Disease/blood ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/physiopathology ; Photometry ; Predictive Value of Tests ; Skin/blood supply
    Chemical Substances Biomarkers ; Oxygen (S88TT14065)
    Language English
    Publishing date 2021-08-17
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2021.05.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Surgical stabilisation in a 13-year-old boy with traumatic flail chest.

    Leenstra, Bernard Simon / Stolwijk, Antoinette / Poeze, Martijn

    BMJ case reports

    2015  Volume 2015

    Abstract: Flail chest after blunt trauma to the chest has a high morbidity and mortality rate. Traumatic flail chest in children rarely occurs due to flexibility of the ribcage. We describe the case of a 13-year-old boy sustaining a flail chest after a high-energy ...

    Abstract Flail chest after blunt trauma to the chest has a high morbidity and mortality rate. Traumatic flail chest in children rarely occurs due to flexibility of the ribcage. We describe the case of a 13-year-old boy sustaining a flail chest after a high-energy trauma. Conservative treatment with proper mechanical ventilation and pain management was unsuccessful, and was followed by operative rib fixation. The patient was discharged home 17 days after surgery and, at 4 months follow-up, had fully recovered. This case report shows the possibility of operative rib fixation as treatment for flail chest in children.
    MeSH term(s) Accidents, Traffic ; Adolescent ; Flail Chest/diagnostic imaging ; Flail Chest/etiology ; Flail Chest/surgery ; Follow-Up Studies ; Fracture Fixation, Internal/methods ; Humans ; Injury Severity Score ; Male ; Radiography ; Respiration, Artificial ; Rib Fractures/complications ; Rib Fractures/diagnostic imaging ; Rib Fractures/surgery ; Treatment Outcome ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/diagnostic imaging ; Wounds, Nonpenetrating/surgery
    Language English
    Publishing date 2015-09-14
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2015-209371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Permethrin-treated bed nets in the prevention of malaria and anemia in adolescent schoolgirls in western Kenya.

    Leenstra, Tjalling / Phillips-Howard, Penelope A / Kariuki, Simon K / Hawley, William A / Alaii, Jane A / Rosen, Daniel H / Oloo, Aggrey J / Nahlen, Bernard L / Kager, Piet A / ter Kuile, Feiko O

    The American journal of tropical medicine and hygiene

    2003  Volume 68, Issue 4 Suppl, Page(s) 86–93

    Abstract: The impact of insecticide (permethrin)-treated bed nets (ITNs) on the health of adolescent schoolgirls was investigated during a community-based, randomized, controlled trial of ITNs in western Kenya. Two school-based cross-sectional surveys were ... ...

    Abstract The impact of insecticide (permethrin)-treated bed nets (ITNs) on the health of adolescent schoolgirls was investigated during a community-based, randomized, controlled trial of ITNs in western Kenya. Two school-based cross-sectional surveys were conducted to determine the prevalence of malaria and anemia in 644 schoolgirls 12-18 years old in a rural area with intense perennial malaria transmission. In 12- and 13-year-old schoolgirls, ITNs were associated with a reduced prevalence of all cause anemia (hemoglobin level <12 g/dL, 16.9% versus 31.4%, adjusted odds ratio [OR] = 0.38, 95% confidence interval [CI] = 0.21, 0.69%) and a 0.34 g/dL (95% CI = 0.02, 0.66) increase in mean hemoglobin concentrations. No beneficial effect on all-cause anemia (adjusted OR = 0.79, 95% CI = 0.43, 1.45) or hemoglobin concentrations (difference in mean = 0.14 g/dL, 95% CI = -0.24, 0.53) was evident in older girls. In all age groups, no effect was found on malaria parasite prevalence or density, clinical malaria, all-cause morbidity, standard measures of nutritional status and growth, or the use of antimalarials and other medications. ITNs approximately halved the prevalence of mild anemia in young, school-attending, non-pregnant, adolescent girls, but had no impact in older girls or on other malaria-associated morbidity or nutritional status.
    MeSH term(s) Adolescent ; Anemia/epidemiology ; Anemia/prevention & control ; Bedding and Linens ; Child ; Female ; Humans ; Insecticides/pharmacology ; Kenya/epidemiology ; Malaria/epidemiology ; Malaria/prevention & control ; Menarche ; Menstruation ; Permethrin/pharmacology ; Prevalence
    Chemical Substances Insecticides ; Permethrin (509F88P9SZ)
    Language English
    Publishing date 2003-04
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.61: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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