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Article: Diagnosis of complicated gynaecological inflammations by computed tomography - one center experience.

Korčáková, Eva / Ferda, Jiří / Presl, Jiří

2023 Volume 88, Issue 6, Page(s) 472–479

Abstract: The aim of this article is to acquaint the gynaecological public with our experience with the use of computed tomography in the diagnosis of fluid collections in women with clinical suspicion of complicated pelvic inflammation or a complication after ... ...

Title translation	Diagnostika komplikovaných gynekologických zánětů pomocí výpočetní tomografie – zkušenosti jednoho centra.
Abstract	The aim of this article is to acquaint the gynaecological public with our experience with the use of computed tomography in the diagnosis of fluid collections in women with clinical suspicion of complicated pelvic inflammation or a complication after gynaecological surgery. We present diagnostic dilemmas that radiologists deal with, including differential diagnoses. We also deal with the benefits for the referring gynaecologist, and we also discuss the possible discrepancy between his expectations and the result of the examination.
MeSH term(s)	Humans ; Female ; Abscess/diagnosis ; Gynecology ; Tomography, X-Ray Computed ; Pelvic Inflammatory Disease/diagnostic imaging ; Pelvic Inflammatory Disease/complications ; Gynecologic Surgical Procedures/adverse effects
Language	English
Publishing date	2023-12-14
Publishing country	Czech Republic
Document type	Journal Article
ZDB-ID	1187094-1
ISSN	1805-4455 ; 1210-7832 ; 0374-6852
ISSN (online)	1805-4455
ISSN	1210-7832 ; 0374-6852
DOI	10.48095/cccg2023472
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Article ; Online: Refractivity corrected distance measurement using the intermode beats derived from a supercontinuum.

Ray, Pabitro / Salido-Monzú, David / Presl, Robert / Avers Butt, Jemil / Wieser, Andreas

Optics express

2024 Volume 32, Issue 7, Page(s) 12667–12681

Abstract: Simultaneous distance measurements on two or more optical wavelengths enable dispersion-based correction of deviations that result from insufficient knowledge of the refractive index along the signal propagation path. We demonstrate a supercontinuum- ... ...

Abstract	Simultaneous distance measurements on two or more optical wavelengths enable dispersion-based correction of deviations that result from insufficient knowledge of the refractive index along the signal propagation path. We demonstrate a supercontinuum-based approach for highly accurate distance measurements suitable for such an inline refractivity compensation. The distance is estimated from the phase delay observations on the intermode beats. We use a supercontinuum (SC) coherently broadened from a 780 nm frequency comb and spanning the spectral range of 570-970 nm. Experiments are performed on the 590 and 890 nm wavelength bands filtered from the SC spectrum. Results show distance measurements with standard deviations of around 0.01 mm at 50 m, and a distance-dependent component below 0.2 ppm on the individual spectral bands. Distance residuals compared to a reference interferometer are on the order of 0.1 ppm for displacements up to 50 m. Controlled pressure-induced refractivity variations are created over a length of 15 m, resulting in an optical path length change of 0.4 mm. Using the two-color method, we demonstrate refractivity-corrected distance measurement with a standard deviation of around 0.08 mm for a 60 s averaging window. The current experimental configuration can be easily extended to distance measurements on more than two wavelengths. The results highlight its potential for practical long-distance measurements through inline refractivity compensation.
Language	English
Publishing date	2024-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.514997
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Article ; Online: Safety, feasibility, and short-term-outcome of anal endoscopic submucosal dissection for anal intraepithelial neoplasia: an option for focal lesions?

Singhartinger, F / Gantschnigg, A / Holzinger, J / Wagner, A / Singhartinger, J / Koch, O / Emmanuel, K / Presl, J

Techniques in coloproctology

2023 Volume 28, Issue 1, Page(s) 18

Abstract: Background: Anal intraepithelial neoplasia (AIN) appears in three different stages. AIN 1 and AIN 2 (p16 negative) are defined as low risk and unlikely to progress to invasive anal cancer. AIN 2 (p16 positive) and AIN 3 are of high risk and should be ... ...

Abstract	Background: Anal intraepithelial neoplasia (AIN) appears in three different stages. AIN 1 and AIN 2 (p16 negative) are defined as low risk and unlikely to progress to invasive anal cancer. AIN 2 (p16 positive) and AIN 3 are of high risk and should be treated because progression rates to anal cancer are around 10% and treatment significantly reduces this risk. The correct treatment is still a matter of debate. Human papilloma virus (HPV) plays a role in the development of AIN. Our aim was to assess anal endoscopic dissection (aESD) as an intervention for AIN3. Methods: We retrospectively evaluated patients who underwent aESD for AIN 3 between December 2017 and March 2023. The interventional technique itself (duration, complications, size of specimen) and patient outcomes (recurrence, progression to anal cancer, re-intervention) were analyzed. Results: Fifteen patients with a median age of 52 years (23-78) underwent aESD for AIN 3. All tested specimens were positive for HPV. Median duration of intervention was 56.1 min, one delayed postinterventional bleeding occurred, and specimen size was 12.05 cm Conclusions: Anal endoscopic submucosal dissection seems to be a safe and feasible treatment for AIN. Recurrences are seldom and can be treated again with the same method. Nevertheless, indications for resection in comparison to radiofrequency ablation, pharmacological therapy, and watch-and-wait strategy are still unclear. Trial registration: Ethics commission of Salzburg, Austria, EK-Nr. 1056/2023. Keywords: Endoscopic submucosal dissection, anal intraepithelial neoplasia, anal cancer.
MeSH term(s)	Humans ; Young Adult ; Adult ; Middle Aged ; Aged ; Endoscopic Mucosal Resection/adverse effects ; Papillomavirus Infections/surgery ; Retrospective Studies ; Feasibility Studies ; Carcinoma in Situ/pathology ; Anus Neoplasms/pathology
Language	English
Publishing date	2023-12-15
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2083309-X
ISSN	1128-045X ; 1123-6337
ISSN (online)	1128-045X
ISSN	1123-6337
DOI	10.1007/s10151-023-02896-x
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Article: Coincidence of giant uterine myomatosis and detection of two advanced malignancies in 77-year-old female patient.

Bláhová, K / Presl, J / Berezovskiy, D / Vlasák, P / Bouda, J / Kosťun, J

Ceska gynekologie

2021 Volume 85, Issue 3, Page(s) 187–192

Abstract: Objective: Our aim is to emphasize the importance of patient participation in screening programs available in the Czech Republic and in preventive gynaecological examinations. As an example, we present a case report of a 77-year-old female patient with ... ...

Title translation	Koincidence obrovské děložní myomatózy a prvozáchytu dvou pokročilých malignit u 77leté pacientky.
Abstract	Objective: Our aim is to emphasize the importance of patient participation in screening programs available in the Czech Republic and in preventive gynaecological examinations. As an example, we present a case report of a 77-year-old female patient with the accumulation of serious gynaecological diseases (extreme uterine myomatosis, breast cancer) and non-Hodgkin´s B-lymphoma. Design: Case report. Setting: Department of Obstetrics and Gynaecology, Faculty Hospital in Pilsen, Charles University Medical Faculty in Pilsen. Case report: Our case report of a 77-year-old patient is a rare case of the simultaneous detection of giant uterine myomatosis causing voluminous ventral hernia, invasive ductal breast cancer, and non-Hodgkin´s B-lymphoma. The patient was not gynecologically examined for last 20 years and did not undergo any screening examinations. In the postoperative period, the patient was diagnosed with invasive ductal breast cancer and follicular lymphoma. All the diseases were diagnosed in advanced stage. Conclusion: The occurrence of bulky fibroids is very rare in postmenopause. Long-term neglect of clinical symptoms and adverse health signals allows their gradual progression. Especially in older patients, other serious illnesses may complicate the situation.
MeSH term(s)	Aged ; Czech Republic ; Female ; Gynecology ; Humans ; Leiomyoma ; Lymphoma, Non-Hodgkin ; Obstetrics ; Pregnancy ; Uterine Neoplasms/complications ; Uterine Neoplasms/diagnosis
Language	English
Publishing date	2021-02-09
Publishing country	Czech Republic
Document type	Case Reports ; Journal Article
ZDB-ID	1187094-1
ISSN	1805-4455 ; 1210-7832 ; 0374-6852
ISSN (online)	1805-4455
ISSN	1210-7832 ; 0374-6852
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Article ; Online: Short-term outcomes and costs analysis of robotic-assisted versus laparoscopic cholecystectomy-a retrospective single-center analysis.

Gantschnigg, Antonia / Koch, Oliver Owen / Singhartinger, Franz / Tschann, Peter / Hitzl, Wolfgang / Emmanuel, Klaus / Presl, Jaroslav

Langenbeck's archives of surgery

2023 Volume 408, Issue 1, Page(s) 299

Abstract: Purpose: Robotic-assisted surgery is an alternative technique for patients undergoing minimal invasive cholecystectomy (CHE). The aim of this study is to compare the outcomes and costs of laparoscopic versus robotic CHE, previously described as the ... ...

Abstract	Purpose: Robotic-assisted surgery is an alternative technique for patients undergoing minimal invasive cholecystectomy (CHE). The aim of this study is to compare the outcomes and costs of laparoscopic versus robotic CHE, previously described as the major disadvantage of the robotic system, in a single Austrian tertiary center. Methods: A retrospective single-center analysis was carried out of all patients who underwent an elective minimally invasive cholecystectomy between January 2010 and August 2020 at our tertiary referral institution. Patients were divided into two groups: robotic-assisted CHE (RC) and laparoscopic CHE (LC) and compared according to demographic data, short-term postoperative outcomes and costs. Results: In the study period, 2088 elective minimal invasive cholecystectomies were performed. Of these, 220 patients met the inclusion criteria and were analyzed. One hundred ten (50%) patients underwent LC, and 110 patients RC. There was no significant difference in the mean operation time between both groups (RC: 60.2 min vs LC: 62.0 min; p = 0.58). Postoperative length of stay was the same in both groups (RC: 2.65 days vs LC: 2.65 days, p = 1). Overall hospital costs were slightly higher in the robotic group with a total of €2088 for RC versus €1726 for LC. Conclusions: Robotic-assisted cholecystectomy is a safe and feasible alternative to laparoscopic cholecystectomy. Since there are no significant clinical and cost differences between the two procedures, RC is a justified operation for training the whole operation team in handling the system as a first step procedure. Prospective randomized trials are necessary to confirm these conclusions.
MeSH term(s)	Humans ; Cholecystectomy, Laparoscopic/methods ; Robotic Surgical Procedures/methods ; Retrospective Studies ; Prospective Studies ; Cholecystectomy/methods ; Laparoscopy ; Operative Time ; Length of Stay
Language	English
Publishing date	2023-08-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1423681-3
ISSN	1435-2451 ; 1435-2443
ISSN (online)	1435-2451
ISSN	1435-2443
DOI	10.1007/s00423-023-03037-6
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Article ; Online: First clinical application of image-guided intraoperative electron radiation therapy with real time intraoperative dose calculation in recurrent rectal cancer: technical procedure.

Roeder, Falk / Fastner, Gerd / Fussl, Christoph / Sedlmayer, Felix / Stana, Markus / Berchtold, Johannes / Jäger, Tarkan / Presl, Jaroslav / Schredl, Philipp / Emmanuel, Klaus / Colleselli, Daniela / Kotolacsi, Gabriel / Scherer, Philipp / Steininger, Philipp / Gaisberger, Christoph

Radiation oncology (London, England)

2023 Volume 18, Issue 1, Page(s) 186

Abstract: Intraoperative radiation therapy (IORT) is a radiation technique applying a single fraction with a high dose during surgery. We report the first abdomino-pelvic application of an image-guided intraoperative electron radiation therapy with intraoperative ... ...

Abstract	Intraoperative radiation therapy (IORT) is a radiation technique applying a single fraction with a high dose during surgery. We report the first abdomino-pelvic application of an image-guided intraoperative electron radiation therapy with intraoperative real time dose calculation based on the individual intraoperative patient anatomy. A patient suffering from locoregionally recurrent rectal cancer after treatment with neoadjuvant re-chemoradiation was chosen for this approach. After surgical removal of the recurrence, an adequate IORT applicator was placed as usual. A novel mobile imaging device (ImagingRing, MedPhoton) was positioned around the patient covering the region to be treated with the IORT-applicator in place. It allowed the acquisition of three-dimensional intraoperative cone-beam computed tomography images suitable for dose calculation using an automated scaling (heuristic object and head scatter as well as hardening corrections) of Hounsfield units. After image acquisition confirmed the correct applicator position, the images were transferred to our treatment planning system for intraoperative dose calculation. Treatment could be accomplished using the calculated dose distribution. We herein describe the details of the procedure including necessary adjustments in the typically used IORT equipment and work flow. We further discuss the pros and cons of this new approach generally overcoming a decade long limitation of IORT procedures as well as future perspectives regarding IORT treatments.
MeSH term(s)	Humans ; Electrons ; Radiotherapy, Image-Guided/methods ; Rectal Neoplasms/diagnostic imaging ; Rectal Neoplasms/radiotherapy ; Rectal Neoplasms/surgery ; Combined Modality Therapy ; Cone-Beam Computed Tomography ; Intraoperative Period ; Intraoperative Care
Language	English
Publishing date	2023-11-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2224965-5
ISSN	1748-717X ; 1748-717X
ISSN (online)	1748-717X
ISSN	1748-717X
DOI	10.1186/s13014-023-02374-6
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Article: The SAlzburg PEritoneal SUrface CAlculator (SAPESUCA): The First Web-Based Application for Peritoneal Surface Area Quantification.

Jäger, Tarkan / Schredl, Philipp / Neureiter, Daniel / Presl, Jaroslav / Tschann, Peter / Königsrainer, Ingmar / Pascher, Andreas / Emmanuel, Klaus / Regenbogen, Stephan / Ramspott, Jan Philipp

Cancers

2023 Volume 15, Issue 12

Abstract: 1) Background: Peritoneal metastasized colorectal cancer is associated with a worse prognosis. The combination of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) showed promising results in selected patients, but ... ...

Abstract	(1) Background: Peritoneal metastasized colorectal cancer is associated with a worse prognosis. The combination of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) showed promising results in selected patients, but standardization is lacking so far. We present the first tool enabling standardized peritoneal surface area (PSA) quantification in patients undergoing CRS and HIPEC: The SAlzburg PEritoneal SUrface CAlculator (SAPESUCA). (2) Methods: SAPESUCA was programmed using the R-Shiny framework. The application was validated in 23 consecutive colon cancer patients who received 27 closed oxaliplatin-based HIPECs between 2016 and 2020. The programming algorithm incorporates the patient's body surface area and its correlated peritoneal surface area (PSA) based on the 13 Peritoneal Cancer Index (PCI) regions. (3) Results: Patients' median age was 56 years. Median PCI was 9. SAPESUCA revealed a mean PSA of 18,613 cm
Language	English
Publishing date	2023-06-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15123134
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Article ; Online: Standardization of rectal cancer surgery and bowel preparation in Austria : A multicenter nationwide survey by the Austrian Society of Surgical Oncology.

Widmann, Kerstin M / Dawoud, Christopher / Harpain, Felix / Aigner, Felix / Presl, Jaroslav / Rosen, Harald / Zitt, Matthias / Schoppmann, Sebastian F / Emmanuel, Klaus / Riss, Stefan

Wiener klinische Wochenschrift

2023 Volume 135, Issue 17-18, Page(s) 457–462

Abstract: Background: Standardized management of colorectal cancer is crucial for achieving an optimal clinical and oncological outcome. The present nationwide survey was designed to provide data about the surgical management of rectal cancer patients. In ... ...

Abstract	Background: Standardized management of colorectal cancer is crucial for achieving an optimal clinical and oncological outcome. The present nationwide survey was designed to provide data about the surgical management of rectal cancer patients. In addition, we evaluated the standard approach for bowel preparation in all centers in Austria performing elective colorectal surgery. Methods: The Austrian Society of Surgical Oncology (ACO["Arbeitsgemeinschaft für chirurgische Onkonlogie"]-ASSO) conducted a multicenter questionnaire-based study comprising 64 hospitals between October 2020 and March 2021. Results: The median number of low anterior resections performed annually per department was 20 (range 0-73). The highest number was found in Vienna, with a median of 27 operations, whereas Vorarlberg was the state with the lowest median number of 13 resections per year. The laparoscopic approach was the standard technique in 46 (72%) departments, followed by the open approach in 30 (47%), transanal total mesorectal excision (TaTME) in 10 (16%) and robotic surgery in 6 hospitals (9%). Out of 64 hospitals 51 (80%) named a standard for bowel preparation before colorectal resections. No preparation was commonly used for the right colon (33%). Conclusion: Considering the low number of low anterior resections performed in each hospital per year in Austria, defined centers for rectal cancer surgery are still scarce. Many hospitals did not transfer recommended bowel preparation guidelines into clinical practice.
MeSH term(s)	Humans ; Austria/epidemiology ; Surgical Oncology ; Laparoscopy/methods ; Rectal Neoplasms/epidemiology ; Rectal Neoplasms/surgery ; Surveys and Questionnaires ; Reference Standards ; Postoperative Complications ; Treatment Outcome
Language	English
Publishing date	2023-06-26
Publishing country	Austria
Document type	Multicenter Study ; Journal Article
ZDB-ID	200462-8
ISSN	1613-7671 ; 0043-5325 ; 0300-5178
ISSN (online)	1613-7671
ISSN	0043-5325 ; 0300-5178
DOI	10.1007/s00508-023-02227-y
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Article: Karcinosarkom endometria s melanomovou diferenciací, kazuistika.

Berezovskiy, D / Vlasák, P / Kosťun, J / Bouda, J / Presl, J

Ceska gynekologie

2017 Volume 82, Issue 5, Page(s) 390–395

Abstract: Objective: The case report presents a case of 60-year old woman with a rare malignant mixed Müllerian tumor with melanomatous differentiation diagnosed from a histology after cervical polyp ablation and curettage.: Design: Case report.: Setting: ... ...

Title translation	Carcinosarcoma of the endometrium with melanocytic differentiation, case report.
Abstract	Objective: The case report presents a case of 60-year old woman with a rare malignant mixed Müllerian tumor with melanomatous differentiation diagnosed from a histology after cervical polyp ablation and curettage. Design: Case report. Setting: Department of gynecology and obstetrics, University Hospital in Pilsen. Conclusion: Carcinosarcoma, previously malignant mixed Müllerian tumor, is a very rare aggressive endometrial carcinoma with low incidence, which typically occurs among older women and commonly affects the uterine body and cervix. Clinically, the carcinosarcoma is impossible to be distinguished from endometrial carcinoma or uterine sarcoma and the definitive diagnosis can only be made based on histological examination.
MeSH term(s)	Carcinosarcoma/pathology ; Endometrial Neoplasms/pathology ; Endometrium ; Female ; Humans ; Middle Aged ; Mixed Tumor, Mullerian/pathology ; Uterine Neoplasms/pathology
Language	Czech
Publishing date	2017-11-07
Publishing country	Czech Republic
Document type	Case Reports ; Journal Article
ZDB-ID	1187094-1
ISSN	1805-4455 ; 1210-7832 ; 0374-6852
ISSN (online)	1805-4455
ISSN	1210-7832 ; 0374-6852
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Article ; Online: Three Centuries of Snowpack Decline at an Alpine Pass Revealed by Cosmogenic Paleothermometry and Luminescence Photochronometry

Guralnik, Benny / Tremblay, Marissa M. / Phillips, Marcia / Sellwood, Elaine L. / Gribenski, Natacha / Presl, Robert / Haberkorn, Anna / Sohbati, Reza / Shuster, David L. / Valla, Pierre G. / Jain, Mayank / Schindler, Konrad / Wallinga, Jakob / Hippe, Kristina

Geophysical Research Letters

2024 Volume 51, Issue 2

Abstract: The spatial and temporal distribution of Alpine snow is a sensitive gauge of environmental change. While understanding past snow dynamics is essential for reconstructing past climate and forecasting future trends, reliable snowpack data prior to the ... ...

Abstract	The spatial and temporal distribution of Alpine snow is a sensitive gauge of environmental change. While understanding past snow dynamics is essential for reconstructing past climate and forecasting future trends, reliable snowpack data prior to the instrumental record are scarce. We present a novel pairing of cosmogenic paleothermometry and luminescence photochronometry which constrain the temperature and insolation history of bedrock outcrops at the Gotthard Pass, Switzerland, over the last ∼15,000 years. By coupling these results with cosmogenic 14C-10Be chronology and modern in situ rock thermometry, we infer a ∼70-day reduction of snowpack at the topographic mid-slope. Our data indicate stable environmental conditions throughout the Holocene, followed by a 6.6 ± 2.9°C increase of ground surface temperature, coeval with an order-of-magnitude or more increase in ground surface insolation. Bracketing the onset of these changes between 1504 and 1807 CE, our findings tie the snowpack decline with the onset of human industrialization.
Keywords	Alpine ; cosmogenic ; luminescence ; snow cover
Subject code	910
Language	English
Publishing country	nl
Document type	Article ; Online
ZDB-ID	7403-2
ISSN	0094-8276
ISSN	0094-8276
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