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  1. Article: Pulmonary endarterectomy reoperation: frequency, risk factors and outcomes.

    Guth, Stefan / Wiedenroth, Christoph B / Mayer, Eckhard

    Annals of cardiothoracic surgery

    2022  Volume 11, Issue 2, Page(s) 166–168

    Language English
    Publishing date 2022-03-20
    Publishing country China
    Document type Editorial
    ZDB-ID 2713627-9
    ISSN 2304-1021 ; 2225-319X
    ISSN (online) 2304-1021
    ISSN 2225-319X
    DOI 10.21037/acs-2021-pte-140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Untersuchungen zur Verbesserung der Lungenkonservierung

    Mayer, Eckhard

    Auswirkungen von Spendervorbehandlung mit Prostaglandin E1 und unterschiedlichen Konservierungslösungen, Konservierungstemperaturen und Beatmungsformen auf die Funktion der Transplantatlunge beim Hund

    1996  

    Author's details von Eckhard Mayer
    Language German
    Size V, 102 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Mainz, Univ., Habil.-Schr., 1997
    Note Mikrofiche-Ausg.: 2 Mikrofiches : 24x
    HBZ-ID HT008067978
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Decision-making in pulmonary endarterectomy surgery.

    Kim, Nick H / Mayer, Eckhard

    The European respiratory journal

    2019  Volume 53, Issue 1

    MeSH term(s) Endarterectomy ; Humans ; Hypertension, Pulmonary ; Patient Preference
    Language English
    Publishing date 2019-01-10
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.02138-2018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Chronic thromboembolic pulmonary hypertension due to an implantable cardioverter-defibrillator's lead thrombosis.

    Triantafyllidi, Helen / Mpahara, Aikaterini / Mademli, Maria / Mayer, Eckhard

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2021  Volume 62, Issue 6, Page(s) 488–489

    MeSH term(s) Chronic Disease ; Defibrillators, Implantable/adverse effects ; Humans ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/therapy ; Pulmonary Embolism/etiology ; Pulmonary Embolism/therapy ; Thrombosis/etiology
    Language English
    Publishing date 2021-01-30
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
    DOI 10.1016/j.hjc.2021.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Therapie der chronisch thromboembolischen pulmonalen Hypertonie

    Wiedenroth, Christoph B. / Mayer, Eckhard / Guth, Stefan

    Aktuelle Kardiologie

    2023  Volume 12, Issue 01, Page(s) 34–38

    Abstract: Die chronisch thromboembolische pulmonale Hypertonie (CTEPH) ist eine wichtige und oft gut behandelbare Form der pulmonalen Hypertonie. Es stehen aktuell 3 Therapiemodalitäten zur Verfügung: die pulmonale Endarteriektomie, die pulmonale ... ...

    Abstract Die chronisch thromboembolische pulmonale Hypertonie (CTEPH) ist eine wichtige und oft gut behandelbare Form der pulmonalen Hypertonie. Es stehen aktuell 3 Therapiemodalitäten zur Verfügung: die pulmonale Endarteriektomie, die pulmonale Ballonangioplastie und die gezielte medikamentöse Behandlung. Das therapeutische Konzept hängt maßgeblich von der Lokalisation der zugrunde liegenden pulmonalarteriellen fibrösen Obstruktionen ab. Die pulmonale Endarteriektomie ist der Goldstandard in der Behandlung der CTEPH. Für inoperable Patienten stehen mittlerweile 2 zugelassene Substanzen (Riociguat und Treprostinil) zur Verfügung. Daneben wird bei Vorhandensein entsprechender Zielgebiete die interventionelle Therapie empfohlen. Evaluation und Behandlung von CTEPH-Patienten sollte in entsprechend erfahrenen Zentren erfolgen.
    Keywords chronisch thromboembolische pulmonale Hypertonie ; pulmonale Endarteriektomie ; pulmonale Ballonangioplastie ; chronic thromboembolic pulmonary hypertension ; pulmonary endarterectomy ; balloon pulmonary angioplasty
    Language German
    Publishing date 2023-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2654127-0
    ISSN 2193-5211 ; 2193-5203
    ISSN (online) 2193-5211
    ISSN 2193-5203
    DOI 10.1055/a-1953-5670
    Database Thieme publisher's database

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  6. Article: Pulmonary endarterectomy: technique and pitfalls.

    Guth, Stefan / Mayer, Eckhard / Prüfer, Diethard / Wiedenroth, Christoph B

    Annals of cardiothoracic surgery

    2022  Volume 11, Issue 2, Page(s) 180–188

    Abstract: Chronic thromboembolic pulmonary hypertension (CTEPH) remains a rare and underdiagnosed disease. After one or several episodes of acute pulmonary embolism, around 3% of patients develop CTEPH and two-thirds of these patients are potential surgical ... ...

    Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) remains a rare and underdiagnosed disease. After one or several episodes of acute pulmonary embolism, around 3% of patients develop CTEPH and two-thirds of these patients are potential surgical candidates. Besides surgery, additional treatment modalities are pulmonary arterial hypertension medication and balloon pulmonary angioplasty. Patients should be evaluated in CTEPH expert centers to ensure the most appropriate therapy. Pulmonary endarterectomy (PEA) is a complex, but standardized surgical procedure aiming to clear the obstructed pulmonary arteries completely. For optimal visualization, deep hypothermic circulatory arrest is a prerequisite. This article will give an overview of the evaluation, indication and surgical management of patients with CTEPH.
    Language English
    Publishing date 2022-03-19
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2713627-9
    ISSN 2304-1021 ; 2225-319X
    ISSN (online) 2304-1021
    ISSN 2225-319X
    DOI 10.21037/acs-2021-pte-185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Chronic thromboembolic pulmonary hypertension-medical, interventional, and surgical therapy.

    Wiedenroth, Christoph B / Pruefer, Diethard / Adameit, Miriam S D / Mayer, Eckhard / Guth, Stefan

    Herz

    2023  Volume 48, Issue 4, Page(s) 280–284

    Abstract: Chronic thromboembolic pulmonary hypertension (CTEPH) is an important late sequela of pulmonary embolism and a common form of pulmonary hypertension. Currently, three specific treatment modalities are available: pulmonary endarterectomy, balloon ... ...

    Title translation Chronische thromboembolische pulmonale Hypertonie – medikamentöse, interventionelle und chirurgische Behandlung.
    Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is an important late sequela of pulmonary embolism and a common form of pulmonary hypertension. Currently, three specific treatment modalities are available: pulmonary endarterectomy, balloon pulmonary angioplasty, and targeted medical therapy. The treatment decision depends mainly on the exact localization of the underlying pulmonary arterial obstructions. Pulmonary endarterectomy is the gold standard treatment of CTEPH. For inoperable patients, riociguat and treprostinil are approved. In addition, interventional therapy is recommended if appropriate target lesions are proven. Evaluation and treatment of patients with CTEPH in experienced centers are mandatory.
    MeSH term(s) Humans ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/surgery ; Chronic Disease ; Pulmonary Embolism/complications ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/surgery ; Pulmonary Artery ; Angioplasty, Balloon/adverse effects
    Language English
    Publishing date 2023-04-25
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 8262-4
    ISSN 1615-6692 ; 0340-9937 ; 0946-1299
    ISSN (online) 1615-6692
    ISSN 0340-9937 ; 0946-1299
    DOI 10.1007/s00059-023-05172-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pulmonary endarterectomy and the cost of patient refusal.

    Kim, Nick H / Mayer, Eckhard

    The European respiratory journal

    2018  Volume 52, Issue 3

    MeSH term(s) Endarterectomy ; Humans ; Hypertension, Pulmonary ; Patient Selection
    Language English
    Publishing date 2018-09-16
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01581-2018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Thesis: Peritonitis

    Mayer, Eckhard

    Ursachen, Komplikationen, Therapie u. Verlauf

    1984  

    Size 1 Mikrofiche
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Mainz, Univ., Diss., 1985
    Note Manuskript: 75 S. : graph. Darst.
    HBZ-ID HT003003232
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Fast functional mapping of ligand-gated ion channels.

    Schmauder, Ralf / Eick, Thomas / Schulz, Eckhard / Sammler, Günther / Voigt, Elmar / Mayer, Günter / Ginter, Holger / Ditze, Günter / Benndorf, Klaus

    Communications biology

    2023  Volume 6, Issue 1, Page(s) 1003

    Abstract: Ligand-gated ion channels are formed by three to five subunits that control the opening of the pore in a cooperative fashion. We developed a microfluidic chip-based technique for studying ion currents and fluorescence signals in either excised membrane ... ...

    Abstract Ligand-gated ion channels are formed by three to five subunits that control the opening of the pore in a cooperative fashion. We developed a microfluidic chip-based technique for studying ion currents and fluorescence signals in either excised membrane patches or whole cells to measure activation and deactivation kinetics of the channels as well as ligand binding and unbinding when using confocal patch-clamp fluorometry. We show how this approach produces in a few seconds either unidirectional concentration-activation relationships at or near equilibrium and, moreover, respective time courses of activation and deactivation for a large number of freely designed steps of the ligand concentration. The short measuring period strongly minimizes the contribution of disturbing superimposing effects such as run-down phenomena and desensitization effects. To validate gating mechanisms, complex kinetic schemes are quantified without the requirement to have data at equilibrium. The new method has potential for functionally analyzing any ligand-gated ion channel and, beyond, also for other receptors.
    MeSH term(s) Ligand-Gated Ion Channels/metabolism ; Ligands
    Chemical Substances Ligand-Gated Ion Channels ; Ligands
    Language English
    Publishing date 2023-10-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-023-05340-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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