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  1. Book ; Online: Avances en el estudio de marcadores moleculares en el diagnóstico y pronóstico de sepsis bacteriana en la ciudad de Cali

    Chávez Vivas, Mónica / Cabrera Tello, Mónica / Martínez Gutiérrez, Alfonsina del Cristo / Gómez Naranjo, Romel Fabian / Rivas Mosquera, Harold / Quintana Ordoñez, Vanessa / Diago Yusti, Juan David / Uribe Díaz, Álvaro / Zamora Salazar, Ingrith / Jaramillo Zapata, Maryury / José Guerrero, Roberto

    2021  

    Keywords Biochemistry ; Marcadores moleculares ; Diagnóstico y pronóstico ; Sepsisbateriana ; Choque séptico ; Poliformismo ; Sepsis abdominal ; Hospital ; Paciente ; Cali ; Colombia
    Language 0|s
    Size 1 electronic resource (1-146 pages)
    Publisher Universidad Santiago de Cali
    Publishing place Colombia
    Document type Book ; Online
    Note Spanish ; Open Access
    HBZ-ID HT021609987
    ISBN 978-958-5147-57-7 ; 958-5147-57-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: The Role of Nursing Care in the Management of External Ventricular Drains on the Neurosurgical Ward: A Quality Improvement Project.

    Alrashidi, Qais / Al-Saadi, Tariq / Alhaj, Ahmad Kh / Diaz, Roberto Jose

    World neurosurgery

    2023  Volume 176, Page(s) 265–271.e2

    Abstract: Objective: The management of external ventricular drains (EVDs) is a critical aspect of patient care in the intensive care setting. However, nurses on the general floor are not commonly exposed to patients with EVD and therefore lack the necessary ... ...

    Abstract Objective: The management of external ventricular drains (EVDs) is a critical aspect of patient care in the intensive care setting. However, nurses on the general floor are not commonly exposed to patients with EVD and therefore lack the necessary knowledge and skills to manage and troubleshoot EVDs effectively. The aim of this study was to evaluate the level of knowledge, comfort, and impact of EVD management among nurses on the floor after the implementation of a quality improvement (QI) tool.
    Methods: This is a cross-sectional study conducted among registered nurses working on the neurosurgical floors of the Montreal Neurological Hospital. Data were collected using a questionnaire based on the plan-do-study-act model. A survey assessing the level of knowledge and comfort with EVD management was conducted before and after the implementation of the QI tool.
    Results: Seventy-six nurses completed the questionnaire regarding their knowledge and comfort level in EVD management. Results showed that only 42% of the nurses reported feeling "comfortable" whereas 37% reported feeling "uncomfortable" in caring for patients with an EVD. In addition, only 6.5% reported being "comfortable" in troubleshooting a malfunctioning EVD. However, the level of comfort significantly improved after using the QI project.
    Conclusions: The results of this study highlight the need for continued training and education to support the care of patients with EVDs in the ward setting. The implementation of a QI tool can significantly improve nurses' knowledge and comfort level in EVD management, leading to improved patient outcomes and overall quality of care.
    MeSH term(s) Humans ; Ventriculostomy/methods ; Clinical Competence ; Cross-Sectional Studies ; Quality Improvement ; Drainage/methods ; Hospitals ; Nursing Care
    Language English
    Publishing date 2023-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.05.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1159: Show issues Location:
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  3. Article ; Online: Frequency and Inertial Response Analysis of Loads in The Chilean Power System

    Juan Quiroz / Roberto Perez / Héctor Chávez / Carlos Fuentes / Matías Díaz / José Rodriguez

    Processes, Vol 11, Iss 2612, p

    2023  Volume 2612

    Abstract: The integration of power electronics-interconnected generation systems to the grid has fostered a significant number of concerns on power system operations, particularly on the displacement of synchronous generators that leads to a reduction in the grid’ ... ...

    Abstract The integration of power electronics-interconnected generation systems to the grid has fostered a significant number of concerns on power system operations, particularly on the displacement of synchronous generators that leads to a reduction in the grid’s overall inertia and frequency response. These concerns have raised a significant amount of state-of-the-art mathematical proposals on how to estimate system inertia; however, the majority of the proposals do not differentiate generator inertia from load inertia. When inertia prediction for control room applications is required in real-time, the current state-of-the-art proposals use the inertia of generators as a proxy for a minimum, overall inertia estimate, counting the number of units committed in real-time and adding up their inertia. However, as dynamic conditions are becoming challenging with the integration of power electronics-interconnected generation systems, it is important to quantify the amount of inertia from the loads, for which the state-of-the-art proposals present very limited advancement, particularly in applications with real data. This work presents a set of recorded actual events in the Chilean power system to estimate the contribution of loads to inertia and frequency response to assess whether the loads have a significant role in frequency stability. The contribution of this work is as follows: first, reporting real data of a power system from the PMU and SCADA systems that are usually classified as not public; and, second, to derive a conclusion from the data to assess the role of loads in frequency stability in a real case.
    Keywords frequency response ; inertia ; power systems ; frequency measurement ; smart grids ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
    Subject code 600
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Classification criteria and commercial profile re-definition of the Family Farm Agriculture in Chile, Maule region

    Roberto Jara-Rojas / José Díaz Osorio / Paula Manríquez / Álvaro Rojas

    Revista de la Facultad de Ciencias Agrarias, Vol 44, Iss

    2022  Volume 1

    Abstract: In Chile, small-scale farmers are classified according to old approaches from 1993 that do not include changes occurred in the last two decades. Maule is the region with most rural population in Chile which represents a significant stratum for ... ...

    Abstract In Chile, small-scale farmers are classified according to old approaches from 1993 that do not include changes occurred in the last two decades. Maule is the region with most rural population in Chile which represents a significant stratum for development, innovation and competitiveness. This study explores a new approach of small-scale farmers -associated with Family Farm Agriculture (AFC) - classification in Chile and it describes a commercial profile or AFC-1 for famers of the Maule Region. A Cluster analysis to determine AFC-1 farmers is used. The analysis includes four association variables: Total Assets, Farm Income, Production Costs and Management Indicators. The results suggest that 16.4% of the farmers have a commercial profile and they could stay out support provided by the National Institute for Agricultural Development (INDAP). This group of farmers would not belong to AFC in short terms. This fact could bring restriction to AFC-1 farmers such as lack of credit access, less investment incentives and technical assistance. Thus, it would expect low process of technology adoption and welfare improvement. New agrarian policies must be warranted to support this important group of famers with a commercial profile.
    Keywords Family Farm Agriculture ; cluster analysis ; commercial profile ; Chile ; Agriculture ; S ; Food processing and manufacture ; TP368-456
    Subject code 306
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Facultad de Ciencias Agrarias. Universidad Nacional de Cuyo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Genetic Susceptibility and Viral Clearance of Hepatitis C Virus infection

    Maria Fernanda Saavedra-Chacón / María Cristina Navas / Neys Suárez-Díaz / Jose Roberto Uribe-Delgado

    Iatreia, Vol 36, Iss 4, Pp 550-

    2023  Volume 561

    Abstract: The hepatitis C virus (HCV) is still one of the leading causes of chronic hepatitis in the western world. Between 15% to 40% of the people acutely infected achieve spontaneous resolution, even though the variables and factors related to the viral ... ...

    Abstract The hepatitis C virus (HCV) is still one of the leading causes of chronic hepatitis in the western world. Between 15% to 40% of the people acutely infected achieve spontaneous resolution, even though the variables and factors related to the viral clearance are not yet fully established. The study of the physiopathological mechanisms of the HCV is essential for the identification of the factors related either to spontaneous resolution or persistence of the viral infection. Some studies have found out variables from the host associated with this outcome, including the interleukin 28 (IL-28B) gene polymorphisms. This gene codifies the lambda 3 interferon (IFNL3). The purpose of this article is to perform a literature review of the physiopathology of HCV infection, describe the evidence of the role of the IL28 gene polymorphisms, and their impact in the spontaneous virus clearance and other aspects of the natural history and treatment of the viral infection.
    Keywords hepatitis c ; immunity ; innate ; physiopathology ; polymorphism ; genetic ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 570
    Language Spanish
    Publishing date 2023-10-01T00:00:00Z
    Publisher Universidad de Antioquia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: In vitro

    Torres, Solange / Figueroa, Fabián / Casas Arrojo, Virginia / Riquelme, Cristian / Astuya, Allisson / Abdala-Díaz, Roberto T / Becerra, José / Rajchenberg, Mario / Pildain, María Belén / Baltazar, Juliano Marcon / Cabrera-Pardo, Jaime R / Pérez, Claudia

    Natural product research

    2024  , Page(s) 1–6

    Abstract: Polysaccharides from wood-rooting fungi have attracted attention due to their broad pharmacological properties. Herein, we report the antitumor and immunomodulatory activities of acid polysaccharides isolated from ... ...

    Abstract Polysaccharides from wood-rooting fungi have attracted attention due to their broad pharmacological properties. Herein, we report the antitumor and immunomodulatory activities of acid polysaccharides isolated from fungi
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2024.2335351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Biorefinery Approach Applied to the Production of Food Colourants and Biostimulants from

    Morillas-España, Ainoa / Bermejo, Ruperto / Abdala-Díaz, Roberto / Ruiz, Ángela / Lafarga, Tomás / Acién, Gabriel / Fernández-Sevilla, José María

    Biology

    2022  Volume 11, Issue 9

    Abstract: In this study, a biorefinery based ... ...

    Abstract In this study, a biorefinery based on
    Language English
    Publishing date 2022-08-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology11091278
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  8. Article ; Online: HLA-A*11:01 and HLA-C*04:01 are associated with severe COVID-19.

    Castro-Santos, Patricia / Rojas-Martinez, Augusto / Riancho, José A / Lapunzina, Pablo / Flores, Carlos / Carracedo, Ángel / Díaz-Peña, Roberto

    HLA

    2023  Volume 102, Issue 6, Page(s) 731–739

    Abstract: We analyzed the association between HLA polymorphisms and susceptibility to SARS-CoV-2 infection and disease severity. Genotyping data from a total of 9373 COVID-19-positive cases from the Spanish Coalition to Unlock Research on Host Genetics on COVID-19 ...

    Abstract We analyzed the association between HLA polymorphisms and susceptibility to SARS-CoV-2 infection and disease severity. Genotyping data from a total of 9373 COVID-19-positive cases from the Spanish Coalition to Unlock Research on Host Genetics on COVID-19 (SCOURGE) consortium and 5943 population controls were included in the study. We found an association of the alleles HLA-B*14:02 and HLA-C*08:02 with a lower risk to COVID-19 infection (p = 0.006, OR = 0.84, 95% CI = [0.75-0.95], p = 0.024, OR = 0.86, 95% CI = [0.78-0.95], respectively). We also found the alleles HLA-A*11:01 and HLA-C*04:01 associated with disease severity (p = 0.033, OR = 1.16, 95% CI = [1.04-1.31], p = 0.045, OR = 1.14, 95% CI = [1.05-1.25], respectively). These results suggest that an effective presentation of viral peptides by HLA class I alleles involve a faster infection clearance, decreasing the susceptibility and severity of COVID-19.
    MeSH term(s) Humans ; COVID-19/genetics ; HLA-C Antigens/genetics ; SARS-CoV-2 ; Gene Frequency ; Alleles ; HLA-A Antigens/genetics
    Chemical Substances HLA-C Antigens ; HLA-A Antigens
    Language English
    Publishing date 2023-08-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2845111-9
    ISSN 2059-2310 ; 2059-2302
    ISSN (online) 2059-2310
    ISSN 2059-2302
    DOI 10.1111/tan.15160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 661: Show issues Location:
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  9. Article ; Online: A more specific concept of a pharmacophore to better rationalize drug design, tailor patient therapy, and tackle bacterial resistance to antibiotics.

    Morán Díaz, Jessica Rubí / Guevara-Salazar, Juan Alberto / Cuevas Hernández, Roberto Issac / Trujillo Ferrara, José Guadalupe

    Expert opinion on drug discovery

    2021  Volume 17, Issue 1, Page(s) 1–4

    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Bacterial Infections/drug therapy ; Drug Design ; Humans
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-10-06
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2259618-5
    ISSN 1746-045X ; 1746-0441
    ISSN (online) 1746-045X
    ISSN 1746-0441
    DOI 10.1080/17460441.2022.1985459
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  10. Article ; Online: Characterization and Biological Activities of the Ulvan Polysaccharide-Rich Fraction Obtained from Ulva rigida and Ulva pseudorotundata and Their Potential for Pharmaceutical Application.

    Fávero Massocato, Thaís / Robles-Carnero, Víctor / Rodrigues Moreira, Bruna / Castro-Varela, Pablo / Bonomi-Barufi, José / Abdala-Díaz, Roberto / Rubi Rörig, Leonardo / López Figueroa, Félix Diego

    Marine biotechnology (New York, N.Y.)

    2024  Volume 26, Issue 2, Page(s) 324–337

    Abstract: Seaweed from the genus Ulva (Ulvales, Chlorophyta) has a worldwide distribution and represents a potential biomass source for biotechnological applications. In the present study, we investigated the ulvan polysaccharide-rich fraction (UPRF) isolated from ...

    Abstract Seaweed from the genus Ulva (Ulvales, Chlorophyta) has a worldwide distribution and represents a potential biomass source for biotechnological applications. In the present study, we investigated the ulvan polysaccharide-rich fraction (UPRF) isolated from two Ulva species (U. rigida and U. pseudorotundata), naturally occurring on the Spanish Mediterranean coast. Chemical characterization of UPRFs was performed in order to explore the polysaccharides' composition. Biological assessments of UPRFs were compared by antioxidant activity and in vitro toxicity tests in the human cell lines: HCT-116 (colon cancer), G-361 (malignant melanoma), U-937 (leukemia), and HaCaT cells (immortalized keratinocytes). Chemical analysis revealed that both UPRFs presented rhamnose as the major relative sugar constituent, followed by glucose in U. rigida and xylose in U. pseudorotundata. Both also presented glucuronic acid, galactose, ribose, and mannose as the remaining monosaccharides. Similar antioxidant activity was obtained, where we observed increased activity in response to increased polysaccharide concentrations. Both UPRFs presented moderate toxicity against HCT-116 cell lines and a selectivity index ≥ 3, suggesting a good potential for use in pharmaceutical products.
    MeSH term(s) Ulva/chemistry ; Humans ; Polysaccharides/pharmacology ; Polysaccharides/chemistry ; Antioxidants/pharmacology ; Antioxidants/chemistry ; HCT116 Cells ; Cell Line, Tumor ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Cell Line ; Spain ; Edible Seaweeds
    Chemical Substances Polysaccharides ; Antioxidants ; ulvan ; Antineoplastic Agents
    Language English
    Publishing date 2024-03-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1479877-3
    ISSN 1436-2236 ; 1436-2228
    ISSN (online) 1436-2236
    ISSN 1436-2228
    DOI 10.1007/s10126-024-10299-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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