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Article ; Online: Sorption of Cobalt and Nickel on Narcissus Tazetta L. Leaf Powder

Süleyman İNAN / Bekir ÖZKAN

Journal of the Turkish Chemical Society, Section A: Chemistry, Vol 8, Iss 3, Pp 705-

2021 Volume 714

Abstract: Narcissus tazetta Linnaeus are grown in the Karaburun district of the Agean Region in Turkey in large quantities. The flower has an economic value; however, the leaves of the plant are of no use. Within this study's scope, sorption behaviors of Narcissus ...

Abstract	Narcissus tazetta Linnaeus are grown in the Karaburun district of the Agean Region in Turkey in large quantities. The flower has an economic value; however, the leaves of the plant are of no use. Within this study's scope, sorption behaviors of Narcissus tazetta L. leaf powder against cobalt and nickel ions were investigated by batch experiments. The effects of initial pH, contact time, initial metal concentration, temperature, and biosorbent dosage were examined using one-factor-at-a-time method. Maximum sorption capacities for Co(II) and Ni(II) were 43.48 and 35.97 mg g-1, respectively. The biosorption process is fast, and the equilibrium was attained in 15 min. for Co(II) and Ni(II). Data fit the pseudo-second-order kinetic model well for both metal ions. Thermodynamic parameters reveal that the biosorption is exothermic and spontaneous. Narcissus tazetta L. Leaf powder is a readily available, costless, and promising biomaterial that can be used to separate Co(II) and Ni(II) ions from an aqueous solution.
Keywords	biosorption ; cobalt ; nickel ; narcissus tazetta ; separation ; Chemistry ; QD1-999
Subject code	660
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	Turkish Chemical Society
Document type	Article ; Online
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Article ; Online: Iloprost treatment on top of infrapopliteal angioplasty accelerates wound healing in critical leg ischemia.

K Ay, Nuray / Inan, Bekir

Vascular

2019 Volume 28, Issue 1, Page(s) 74–80

MeSH term(s)	Administration, Intravenous ; Aged ; Angioplasty, Balloon/adverse effects ; Angioplasty, Balloon/instrumentation ; Cardiovascular Agents/administration & dosage ; Cardiovascular Agents/adverse effects ; Coated Materials, Biocompatible ; Critical Illness ; Drug Administration Schedule ; Female ; Humans ; Iloprost/administration & dosage ; Iloprost/adverse effects ; Ischemia/diagnosis ; Ischemia/physiopathology ; Ischemia/surgery ; Lower Extremity/blood supply ; Male ; Middle Aged ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/physiopathology ; Peripheral Arterial Disease/therapy ; Retrospective Studies ; Time Factors ; Treatment Outcome ; Vascular Access Devices ; Wound Healing/drug effects
Chemical Substances	Cardiovascular Agents ; Coated Materials, Biocompatible ; Iloprost (JED5K35YGL)
Language	English
Publishing date	2019-07-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2137151-9
ISSN	1708-539X ; 1708-5381
ISSN (online)	1708-539X
ISSN	1708-5381
DOI	10.1177/1708538119866608
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Zs.A 4277: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Venous Insufficiency in Pediatric Patients

Melike Elif TEKER AÇIKEL / Bekir İNAN

Bezmiâlem Science, Vol 7, Iss 4, Pp 307-

2019 Volume 310

Abstract: Objective:The diagnosis and treatment of chronic venous disease has been well standardized in adults. However, the diagnosis of chronic venous insufficiency in pediatric patients, except for Klippel-Trénaunay syndrome and post-thrombotic syndrome, could ... ...

Abstract	Objective:The diagnosis and treatment of chronic venous disease has been well standardized in adults. However, the diagnosis of chronic venous insufficiency in pediatric patients, except for Klippel-Trénaunay syndrome and post-thrombotic syndrome, could not be established. In this retrospective study, we planned to present pediatric patients diagnosed with venous insufficiency by our clinic.Methods:Between January 2016 and May 2018, patients under 18 years of age who were referred to our clinic were included in this study. Venous Doppler ultrasonography was performed in patients and reflux in deep and superficial veins was evaluated. The reflux time is simply duration of inverse flow. A reflux time of >500 ms was used to define the valve insufficiency of the superficial and perforating veins. A reflux time of >1 s was used to define the valve insufficiency of the deep venous system. Venous reflux parameters were compared using t-test.Results:Twenty-five patients were identified in this study. The mean age of the patients was 12 (4-17) years. As a result of clinical examination, 11 patients had varicose venous or venous malformation, 9 patients had swelling (pedal edema), and 6 patients had edema or venous ulcer. Two patients had normal examination findings. Chronic inflammation, hyperpigmentation was not present. No venous thrombomboemboli story was available in any patient.Conclusion:The uncertainty of the factors that cause venous reflux in children still maintains itself today. However, this uncertainty will continue for a long time as the methods used in the diagnosis and treatment of chronic venous disease are the same in both adults and children.
Keywords	child patients ; venous ınsufficiency ; doppler ultrason ; tromboemboli ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2019-10-01T00:00:00Z
Publisher	Galenos Publishing House
Document type	Article ; Online
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Article: The relationship between left ventricular mass index and body composition in new-diagnosed hypertensive patients.

Karakan, Sebnem / Inan, Bekir

Clinical hypertension

2015 Volume 21, Page(s) 23

Abstract: Background: Cardiovascular disease (CVD) is considered a public health burden and most common cause of mortality in all over the world. The latency time for developing CVD may be several decades. the objective of this study was to examine the ... ...

Abstract	Background: Cardiovascular disease (CVD) is considered a public health burden and most common cause of mortality in all over the world. The latency time for developing CVD may be several decades. the objective of this study was to examine the relationship between body composition and Left Ventriculare Mass Index (LVMI) in newly diognosed hypertensive patients. Methods: We enrolled 120 new-diagnosed hypertensive patients (mean age 45 ± 8 years) who admitted to our nephrology clinic. Body fat percentage (BFP) was measured by bioelectrical impedance (BIA). Echocardiography examinations were performed for all patients. Results: Mean values of Waist hip ratio, Body mass ındex, Body fat percentage, Systolic blood pressure, Diastolic blood pressure were significantly higher for females than males (all p values <0.05). The female patients had higher LVMI than male patients (94.8 ± 13.1 vs 89.2 ± 14.6, p < 0.05). The study patients were divided into 3 groups according to their BFP defined by BIA. Group 3 patients, who exhibited higher body fat, had significantly higher BMI (p < 0,05), total leukocyte count (p < 0.05), CRP (p < 0.05), triglyceride (p < 0.05), and female predominance. Group 3 patients were statistically older than group 1 patients (46.2 vs. 40.6 years, p < 0.05). Additionally, LVMI levels were higher in Group 3 than Group 1 (p < 0.05) (Table 3). In logistic regression analysis, independent factors affecting LVMI were age, weight, gender and BFP (all p values were <0.05). Conclusions: BFP was associated with higher LVMI, in newly diognosed hypertensive patients. Its use results in significantly lower proportions of individuals with LVH in the population, in particular among hypertensive and the obese patients.
Language	English
Publishing date	2015-12-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2806585-2
ISSN	2056-5909
ISSN	2056-5909
DOI	10.1186/s40885-015-0033-6
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Article ; Online: Amplitude of Accommodation in Patients with Multiple Sclerosis.

Küçük, Bekir / Hamamcı, Mehmet / Aslan Bayhan, Seray / Bayhan, Hasan Ali / Inan, Levent Ertuğrul

Current eye research

2019 Volume 44, Issue 11, Page(s) 1271–1277

Abstract: ... ...

Abstract	Purpose
MeSH term(s)	Accommodation, Ocular/physiology ; Adult ; Cross-Sectional Studies ; Evoked Potentials, Visual/physiology ; Female ; Follow-Up Studies ; Humans ; Male ; Multiple Sclerosis/physiopathology ; Prospective Studies ; Retinal Ganglion Cells/pathology ; Tomography, Optical Coherence/methods ; Visual Acuity
Language	English
Publishing date	2019-06-20
Publishing country	England
Document type	Journal Article
ZDB-ID	82079-9
ISSN	1460-2202 ; 0271-3683
ISSN (online)	1460-2202
ISSN	0271-3683
DOI	10.1080/02713683.2019.1629596
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Article ; Online: Can the arterial clamp method be used safely where a tourniquet cannot be used?

Erdogan, Ozgur / Gürkan, Volkan / Sönmez, Cavide / Erden, Tunay / Atasoy, Sezen / Yildiz, Fatih / İnan, Bekir / Adilli, Adile

Cardiovascular journal of Africa

2021 Volume 32, Issue 5, Page(s) 254–260

Abstract: Background: Clamp application is safe and widely used in the visceral organs. This raises the question: why not use clamping in orthopaedic, oncological, fracture and revision surgeries of areas where tourniquets are not suitable. This experimental ... ...

Abstract	Background: Clamp application is safe and widely used in the visceral organs. This raises the question: why not use clamping in orthopaedic, oncological, fracture and revision surgeries of areas where tourniquets are not suitable. This experimental animal study aimed to compare tourniquet and arterial clamp applications with regard to their histological effects and inflammatory responses on a molecular level, on the artery, vein, nerve and muscle tissue. Methods: Twenty-one rabbits were divided into three groups (group I: proximal femoral artery clamp; group II: proximal thigh tourniquet; and group III: control group). In the clamp group, the common femoral artery was clamped with a microvascular clamp for two hours. In the tourniquet group, a 12-inch cuff was applied to the proximal thigh for two hours at 200 mmHg. The common femoral artery, vein, nerve, rectus femoris and tibialis anterior muscles were excised and analysed in all groups. Results: Artery and vein endothelial injuries were found in the clamp and tourniquet groups (relative to the control group, Conclusions: We found there were no differences in incidence of vessel, muscle and nerve injury when comparing the tourniquet and clamp applications. For surgical procedures that are unsuited to a tourniquet, arterial clamping can be selected, resulting in close-to-tourniquet vessel injury rates but without tourniquet-related complications.
MeSH term(s)	Animals ; Constriction ; Femoral Artery/surgery ; Lower Extremity ; Muscle, Skeletal ; Rabbits ; Tourniquets
Language	English
Publishing date	2021-07-07
Publishing country	South Africa
Document type	Journal Article
ZDB-ID	2383233-2
ISSN	1680-0745 ; 1996-3467 ; 1015-9657 ; 1995-1892
ISSN (online)	1680-0745 ; 1996-3467
ISSN	1015-9657 ; 1995-1892
DOI	10.5830/CVJA-2021-023
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Zs.A 4813: Show issues

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Article: Multiple Non-Essential Transition Metals Are Accumulated in Carotid Atherosclerotic Plaques: Missing Link in Atherosclerosis?

Olcay, Ayhan / Tezcan, Erdem / Canturk, Emir / İnan, Bekir / Karaoglu, Hasan / Kucuk, Ceyhun / Akdemir, Baris / Yolay, Onur

Biological trace element research. 2019 June, v. 189, no. 2

2019

Abstract: Population studies revealed that metal exposure through food, environment, and smoking was related with increased risk of cardiovascular disease. In this study, we determined complex chemical elements in surgical carotid endarterectomy specimens and ... ...

Abstract	Population studies revealed that metal exposure through food, environment, and smoking was related with increased risk of cardiovascular disease. In this study, we determined complex chemical elements in surgical carotid endarterectomy specimens and carotid tissues from autopsies without atherosclerosis. Atherosclerotic plaques from 41 endarterectomies and normal carotid tissue from 30 autopsies were collected and elemental composition was determined by inductively coupled plasma optical emission spectrometry (ICP-OES) method. Eleven (26.8%) patients never smoked in carotid endarterectomy group. One patient was brass souvenir worker and one was goldsmith and others did not have direct contact with metals in the carotid endarterectomy group. Na, Cu, Mn, Bi, Co, Mo, Ni, Pb, Sb, Se, Sn, Ti, and W levels were not different between two groups. Bi, Co, Mo, Pb, Ti, and W were below the detection limit of ICP-OES in both groups. Concentrations of Mg, K, Ca, P, Fe, B, Zn, Al, As, Cr, Pt, and Hg were significantly higher in carotid endarterectomies than normal carotid tissue samples. Cd and S values were significantly higher in autopsy samples. There is significant multiple non-essential transition metal accumulation in atherosclerotic carotid endarterectomy plaques. The cardiovascular consequences of metal toxicity have not been researched adequately due to large emphasis on the role of cholesterol in atherosclerosis. High level of non-essential transition metal elements in the carotid atherosclerotic plaques may add the missing link of atherogenesis and may necessitate new treatment and prevention strategies in carotid disease if confirmed by further research.
Keywords	aluminum ; antimony ; arsenic ; atherogenesis ; atherosclerosis ; atomic absorption spectrometry ; bismuth ; boron ; cadmium ; calcium ; cholesterol ; chromium ; cobalt ; copper ; detection limit ; elemental composition ; iron ; lead ; magnesium ; manganese ; mercury ; molybdenum ; necropsy ; nickel ; patients ; phosphorus ; platinum ; potassium ; selenium ; sodium ; tin ; titanium ; toxicity ; tungsten ; zinc
Language	English
Dates of publication	2019-06
Size	p. 420-425.
Publishing place	Springer US
Document type	Article
ZDB-ID	445336-0
ISSN	1559-0720 ; 0163-4984
ISSN (online)	1559-0720
ISSN	0163-4984
DOI	10.1007/s12011-018-1481-0
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Comparative efficacy and life quality effects of surgical stripping, radiofrequency ablation, and cyanoacrylate embolization in patients undergoing treatment for great saphenous vein insufficiency.

Ay, Yasin / Gunes, Esra / Turkkolu, Sevket Tuna / Selcuk, Emre / Calim, Muhittin / Akal, Ramazan / Aydin, Cemalettin / Inan, Bekir / Koksal, Cengiz / Kahraman Ay, Nuray

Phlebology

2020 Volume 36, Issue 1, Page(s) 54–62

Abstract: Objectives: To compare traditional surgery with two minimally invasive endo-venous procedures in terms of their long-term effect on the quality of life in great saphenous vein insufficiency (GSV).: Method: This prospective observational study ... ...

Abstract	Objectives: To compare traditional surgery with two minimally invasive endo-venous procedures in terms of their long-term effect on the quality of life in great saphenous vein insufficiency (GSV). Method: This prospective observational study included 217 patients that underwent surgical stripping (n = 62), radiofrequency ablation (n = 70), or cyanoacrylate embolization (n = 85) for the treatment of GSV insufficiency. Venous Clinical Severity Score (VCSS) assessments were made, 36-item Short-Form Health Survey (SF-36) questionnaire and Chronic Venous Insufficiency quality of life Questionnaire (CIVIQ-14) were administered, before and 1 year after the treatments. Results: Surgical stripping group had significantly higher closure rates than the other groups (p < 0.05). At 12 months, decrease in VCSS scores was less pronounced in the cyanoacrylate embolization group when compared to the other two groups (p < 0.05). Improvement in CIVIQ-14 scores was better in the radiofrequency ablation group when compared to the cyanoacrylate embolization group (p < 0.05). Surgical stripping or radiofrequency ablation groups performed better on several domains of SF-36, when compared to the cyanoacrylate embolization group. Conclusions: Surgical stripping and radiofrequency ablation seem to provide a better quality of life results at one year in patients undergoing treatment for GSV insufficiency.
MeSH term(s)	Cyanoacrylates ; Humans ; Quality of Life ; Radiofrequency Ablation ; Saphenous Vein/surgery ; Time Factors ; Treatment Outcome ; Varicose Veins ; Venous Insufficiency/surgery
Chemical Substances	Cyanoacrylates
Language	English
Publishing date	2020-08-02
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	645172-x
ISSN	1758-1125 ; 0268-3555
ISSN (online)	1758-1125
ISSN	0268-3555
DOI	10.1177/0268355520947292
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Article ; Online: Multiple Non-Essential Transition Metals Are Accumulated in Carotid Atherosclerotic Plaques: Missing Link in Atherosclerosis?

Olcay, Ayhan / Tezcan, Erdem / Canturk, Emir / İnan, Bekir / Karaoglu, Hasan / Kucuk, Ceyhun / Akdemir, Baris / Yolay, Onur

Biological trace element research

2018 Volume 189, Issue 2, Page(s) 420–425

Abstract	Population studies revealed that metal exposure through food, environment, and smoking was related with increased risk of cardiovascular disease. In this study, we determined complex chemical elements in surgical carotid endarterectomy specimens and carotid tissues from autopsies without atherosclerosis. Atherosclerotic plaques from 41 endarterectomies and normal carotid tissue from 30 autopsies were collected and elemental composition was determined by inductively coupled plasma optical emission spectrometry (ICP-OES) method. Eleven (26.8%) patients never smoked in carotid endarterectomy group. One patient was brass souvenir worker and one was goldsmith and others did not have direct contact with metals in the carotid endarterectomy group. Na, Cu, Mn, Bi, Co, Mo, Ni, Pb, Sb, Se, Sn, Ti, and W levels were not different between two groups. Bi, Co, Mo, Pb, Ti, and W were below the detection limit of ICP-OES in both groups. Concentrations of Mg, K, Ca, P, Fe, B, Zn, Al, As, Cr, Pt, and Hg were significantly higher in carotid endarterectomies than normal carotid tissue samples. Cd and S values were significantly higher in autopsy samples. There is significant multiple non-essential transition metal accumulation in atherosclerotic carotid endarterectomy plaques. The cardiovascular consequences of metal toxicity have not been researched adequately due to large emphasis on the role of cholesterol in atherosclerosis. High level of non-essential transition metal elements in the carotid atherosclerotic plaques may add the missing link of atherogenesis and may necessitate new treatment and prevention strategies in carotid disease if confirmed by further research.
MeSH term(s)	Aged ; Atherosclerosis/metabolism ; Atherosclerosis/surgery ; Endarterectomy ; Female ; Humans ; In Vitro Techniques ; Ischemic Attack, Transient/metabolism ; Ischemic Attack, Transient/surgery ; Male ; Metals/metabolism ; Metals, Heavy/metabolism ; Middle Aged ; Plaque, Atherosclerotic/metabolism ; Plaque, Atherosclerotic/surgery ; Spectrophotometry, Atomic
Chemical Substances	Metals ; Metals, Heavy
Language	English
Publishing date	2018-08-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	445336-0
ISSN	1559-0720 ; 0163-4984
ISSN (online)	1559-0720
ISSN	0163-4984
DOI	10.1007/s12011-018-1481-0
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Article ; Online: Effects of Cilostazol and Diltiazem Hydrochloride on Ischemia-Reperfusion Injury in a Rat Hindlimb Model.

Inan, Bekir / Sönmez Ergün, Selma / Nurten, Asiye / Küçükgergin, Canan / Zengin Türkmen, Aslı / Seçkin, Şule / Erkalp, Kerem / Ziyade, Sedat

The heart surgery forum

2017 Volume 20, Issue 2, Page(s) E058–E065

Abstract: Objective: Free radicals and neutrophils are potent sources of ischemia-reperfusion injury (I/R) and they can be limited by the use of exogenous application of some therapeutic agents. The objective of this study was to compare the effects of cilostazol ...

Abstract	Objective: Free radicals and neutrophils are potent sources of ischemia-reperfusion injury (I/R) and they can be limited by the use of exogenous application of some therapeutic agents. The objective of this study was to compare the effects of cilostazol and diltiazem hydrochloride in a rat hind limb model of I/R injury. Methods: Skeletal muscles submitted to 2 hours of ischemia by placing an aneurysm clip to femoral artery and reperfused after 1, 2 and 4 hours. Seventy-two Wistar-Albino rats were randomly divided into mainly four groups according to treatment agents: Group I (control group) was treated with saline; Group II was treated with diltiazem hydrochloride; Group III was treated with cilostazol in 30% dimethyl sulphoxide; and Group IV was treated with 30% dimethyl sulphoxide intraperitoneally. These four main groups also subdivided into three subgroups according to duration of the reperfusion times. Blood samples were taken and all rats were sacrificed. Results: Cilostazol-treated groups demonstrated a significant decrease in tissue and serum malondialdehyde (MDA) levels, and tissue myeloperoxidase (MPO ) activity compared with other groups. Increase in serum nitric oxide (NOx) level was significantly higher in all subgroups of cilastazol, diltiazem hydrochloride, and dimethyl sulphoxide groups versus the control group. Conclusion: Although these results suggest the beneficial effects of cilostazol and diltiazem hydrochloride on I/R injury, the effect of cilostazol on I/R injury seems to be more efficient than diltiazem hydrochloride.
Language	English
Publishing date	2017-04-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	2069188-9
ISSN	1522-6662 ; 1098-3511
ISSN (online)	1522-6662
ISSN	1098-3511
DOI	10.1532/hsf.1663
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