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  1. Article ; Online: Conversations with the dying patient.

    Kukran, Sebi / Minocha, Amal

    The clinical teacher

    2018  Volume 16, Issue 6, Page(s) 649–650

    MeSH term(s) Communication ; Death ; Education, Medical/organization & administration ; Humans ; Students, Medical/psychology ; Terminal Care/organization & administration ; Terminal Care/psychology
    Language English
    Publishing date 2018-12-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2151518-9
    ISSN 1743-498X ; 1743-4971
    ISSN (online) 1743-498X
    ISSN 1743-4971
    DOI 10.1111/tct.12994
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  2. Article ; Online: The Differential Effect of Antibodies on Radiographic Progression in Rheumatoid Arthritis.

    Minocha, Amal / Kukran, Sebi / Yee, Philip / Nisar, Muhammad

    Mediterranean journal of rheumatology

    2020  Volume 31, Issue 4, Page(s) 393–399

    Abstract: Background/objectives: The presence of bony erosions in patients with RA is a marker of disease severity and once present they are largely irreversible. Previous studies have shown that the presence of both rheumatoid factor (RF) and anti-cyclic ... ...

    Abstract Background/objectives: The presence of bony erosions in patients with RA is a marker of disease severity and once present they are largely irreversible. Previous studies have shown that the presence of both rheumatoid factor (RF) and anti-cyclic citrullinated peptide (ACPA) antibodies is associated with erosive burden. The aim of our study is to determine the strength of relationship between antibody status and the presence of radiographic erosions at diagnosis.
    Methods: A retrospective study of patients diagnosed with RA at a large university teaching hospital between January 1981 and December 2018. Clinical records were reviewed to determine antibody status, diagnosis date, duration of symptoms, DAS-28, age, ethnicity and whether the 1987 RA criteria was met. The presence of erosions at diagnosis were determined from plain film radiographs reports of hands and feet of patients. Statistical analysis was done using a Chi Square Model and Mann Whitney two-tailed U test.
    Results: There were 774 patients diagnosed with RA in our cohort. 367 (47%) of them were RF+/ACPA+, 87 (11%) were RF+/ACPA-, 66 (9%) were RF-/ACPA+ and 254 (33%) were antibody negative. 127 patients had erosions at the time of diagnosis. Patients in the double positive group had a significantly higher (p=0.003) erosion burden compared to the double negative group i.e. 21.5% in RF+/ACPA+ versus 11.0% in RF-/ACPA- group. The erosion burdens in RF+/ACPA- and RF-/ACPA+ groups were 13.7% and 12.1% respectively.
    Conclusions: Our results show that patients RF+/ACPA+ have nearly two-fold higher incidence of radiographic erosions than patients who are RF-/ACPA-.
    Language English
    Publishing date 2020-12-22
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 3019943-8
    ISSN 2529-198X ; 2459-3516
    ISSN (online) 2529-198X
    ISSN 2459-3516
    DOI 10.31138/mjr.31.4.393
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  3. Article ; Online: Lessons learned from the COVID-19 pandemic: Improving initial investigations with the implementation of a COVID-19 blood request panel.

    Jegatheeswaran, Lavandan / Choi, Byung / Cohn, Martin / Minocha, Amal / Mutengesa, Ernest / Zala, Ashik / Alhilani, Michel

    The International journal of risk & safety in medicine

    2022  Volume 33, Issue S1, Page(s) S53–S56

    Abstract: Background: During the COVID-19 pandemic, the Hillingdon Hospitals NHS Foundation Trust produced trust guidelines for the initial blood investigation of COVID-19 inpatients. However, insufficient education meant inconsistent adherence to this guidance.!# ...

    Abstract Background: During the COVID-19 pandemic, the Hillingdon Hospitals NHS Foundation Trust produced trust guidelines for the initial blood investigation of COVID-19 inpatients. However, insufficient education meant inconsistent adherence to this guidance.
    Objective: To examine whether the implementation of a COVID-19 blood request panel improves adherence to local trust guidelines.
    Method: Between March and April 2020, initial blood investigations performed for positive COVID-19 cases were compared to guidelines. Results were presented locally and a COVID-19 panel was added to the electronic system that provided prompts for appropriate investigations. A re-audit between May and June 2020 was conducted to assess adherence post-intervention.
    Results: 383 patients were identified in the initial audit cohort and a sample of 20 patients were re-audited. Adherence to Full Blood Count, Urea and Electrolytes, C-reactive Protein and Liver Function Tests increased to 100% from 99.7% (p = 0.8), 99.2% (p = 0.69), 98.7% (p = 0.61), and 96.6% (p = 0.4) respectively. Coagulation screen adherence increased to 90% from 72.8% (p = 0.09). Appropriate requesting of D dimers increased to 50% from 19.9% (p = 0.001). Inappropriate troponin requesting decreased to 26.3% from 38.9% (p = 0.23).
    Conclusion: A user-friendly COVID-19 panel of investigations resulted in improved adherence to guidelines. Clear communication and education are essential to help alleviate uncertainty during a pandemic.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics ; Blood Cell Count ; Blood Group Antigens
    Chemical Substances Blood Group Antigens
    Language English
    Publishing date 2022-06-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1055458-0
    ISSN 1878-6847 ; 0924-6479
    ISSN (online) 1878-6847
    ISSN 0924-6479
    DOI 10.3233/JRS-227024
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    Zs.A 3083: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Survey of ophthalmology practitioners in A&E on current COVID-19 guidance at three Major UK Eye Hospitals.

    Minocha, Amal / Sim, Sing Yue / Than, Jonathan / Vakros, Georgios

    Eye (London, England)

    2020  Volume 34, Issue 7, Page(s) 1243–1245

    MeSH term(s) Attitude of Health Personnel ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Emergency Treatment ; Humans ; Ophthalmology ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; United Kingdom
    Keywords covid19
    Language English
    Publishing date 2020-04-07
    Publishing country England
    Document type Letter
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-020-0857-5
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  5. Article ; Online: Correction: Aflibercept for treatment-naïve diabetic macula oedema in a multi-ethnic population: Real-world outcomes from North West London.

    Dinah, Christiana / Ghulakhszian, Arevik / Sim, Sing Yue / Minocha, Amal / Nokhostin, Soroush / Posner, Esther / Cheong-Lee, Richard / George, Sheena

    PloS one

    2021  Volume 16, Issue 9, Page(s) e0257707

    Abstract: This corrects the article DOI: 10.1371/journal.pone.0246626.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.pone.0246626.].
    Language English
    Publishing date 2021-09-16
    Publishing country United States
    Document type Published Erratum
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0257707
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  7. Article ; Online: Interventional radiology training: a comparison of 5 English-speaking countries.

    Mandal, Indrajeet / Minocha, Amal / Yeung, Jason / Bandula, Steve / Rabouhans, Jeremy

    The British journal of radiology

    2019  Volume 93, Issue 1105, Page(s) 20190340

    Abstract: Objective: To compare key characteristics of interventional radiology (IR) training in the UK with four other English-speaking countries (USA, Canada, Australia and New Zealand) and summarise requirements for training.: Methods: Main features ... ...

    Abstract Objective: To compare key characteristics of interventional radiology (IR) training in the UK with four other English-speaking countries (USA, Canada, Australia and New Zealand) and summarise requirements for training.
    Methods: Main features examined were career pathway and requirements, examinations required, specific competition for IR and the process of applying for training as an international medical graduate. Data were collected from official governing body publications, literature and personal experience.
    Results: Several differences were highlighted, including length of training (ranging from 6 to 9 years after medical school), length of IR-specific training (ranging from 1 to 3 years) and examinations required (USA and Canada have additional IR-specific examinations). The level of competition is generally high, in all countries.
    Conclusions: With the demand for IR services set to increase over the next few years, it is crucial that more IR specialists are trained to meet this demand. Awareness of training structures in other countries can highlight opportunity and pitfalls, and help ensure the number of highly trained interventional radiologists in the UK continues to grow.
    MeSH term(s) Australia ; Canada ; Career Choice ; Education, Medical, Graduate/trends ; Educational Measurement ; Humans ; New Zealand ; Radiology, Interventional/education ; United Kingdom ; United States
    Language English
    Publishing date 2019-10-23
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20190340
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  8. Article ; Online: Survey of ophthalmology practitioners in A&E on current COVID-19 guidance at three Major UK Eye Hospitals

    Minocha, Amal / Sim, Sing Yue / Than, Jonathan / Vakros, Georgios

    Eye

    2020  Volume 34, Issue 7, Page(s) 1243–1245

    Keywords Ophthalmology ; General Arts and Humanities ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-020-0857-5
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  9. Article ; Online: Comment on: 'Quantification of anterior chamber reaction after intravitreal injections of conbercept and ranibizumab: a pilot study'.

    Minocha, Amal / Liu, Xiaoxuan / Denniston, Alastair K / Petrushkin, Harry / Solebo, Ameenat L

    Eye (London, England)

    2019  Volume 34, Issue 8, Page(s) 1482–1484

    MeSH term(s) Angiogenesis Inhibitors/adverse effects ; Anterior Chamber ; Humans ; Intravitreal Injections ; Pilot Projects ; Ranibizumab ; Recombinant Fusion Proteins
    Chemical Substances Angiogenesis Inhibitors ; Recombinant Fusion Proteins ; KH902 fusion protein (1P05PW62F3) ; Ranibizumab (ZL1R02VT79)
    Language English
    Publishing date 2019-10-30
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-019-0657-y
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  10. Article ; Online: The impact of the COVID-19 pandemic on final year medical students in the United Kingdom: a national survey.

    Choi, Byung / Jegatheeswaran, Lavandan / Minocha, Amal / Alhilani, Michel / Nakhoul, Maria / Mutengesa, Ernest

    BMC medical education

    2020  Volume 20, Issue 1, Page(s) 206

    Abstract: Background: The coronavirus disease (COVID-19) global pandemic has resulted in unprecedented public health measures. This has impacted the UK education sector with many universities halting campus-based teaching and examinations. The aim of this study ... ...

    Abstract Background: The coronavirus disease (COVID-19) global pandemic has resulted in unprecedented public health measures. This has impacted the UK education sector with many universities halting campus-based teaching and examinations. The aim of this study is to identify the impact of COVID-19 on final year medical students' examinations and placements in the United Kingdom (UK) and how it might impact their confidence and preparedness going into their first year of foundation training.
    Methods: A 10-item online survey was distributed to final year medical students across 33 UK medical schools. The survey was designed by combining dichotomous, multiple choice and likert response scale questions. Participants were asked about the effect that the COVID-19 global pandemic had on final year medical written exams, electives, assistantships and objective structured clinical examinations (OSCEs). The survey also explored the student's confidence and preparedness going into their first year of training under these new unprecedented circumstances.
    Results: Four hundred forty students from 32 UK medical schools responded. 38.4% (n = 169) of respondents had their final OSCEs cancelled while 43.0% (n = 189) had already completed their final OSCEs before restrictions. 43.0% (n = 189) of assistantship placements were postponed while 77.3% (n = 340) had electives cancelled. The impact of COVID-19 on OSCEs, written examinations and student assistantships significantly affected students' preparedness (respectively p = 0.025, 0.008, 0.0005). In contrast, when measuring confidence, only changes to student assistantships had a significant effect (p = 0.0005). The majority of students feel that measures taken during this pandemic to amend their curricula was necessary. Respondents also agree that assisting in hospitals during the outbreak would be a valuable learning opportunity.
    Conclusions: The impact on medical student education has been significant, particularly affecting the transition from student to doctor. This study showed the disruptions to student assistantships had the biggest effect on students' confidence and preparedness. For those willing to assist in hospitals to join the front-line workforce, it is crucial to maintain their wellbeing with safeguards such as proper inductions, support and supervision.
    MeSH term(s) Anxiety/psychology ; Attitude of Health Personnel ; COVID-19 ; Clinical Competence ; Coronavirus Infections/psychology ; Education, Medical, Undergraduate/statistics & numerical data ; Fear ; Female ; Humans ; Male ; Pandemics ; Pneumonia, Viral/psychology ; Students, Medical/psychology ; Surveys and Questionnaires ; United Kingdom ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-06-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-020-02117-1
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