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  1. Article ; Online: Molecular and Morphological Investigations of the Stauros-bearing, Raphid Pennate Diatoms (Bacillariophyceae): Craspedostauros E.J. Cox, and Staurotropis T.B.B. Paddock, and their Relationship to the Rest of the Mastogloiales.

    Ashworth, Matt P / Lobban, Christopher S / Witkowski, Andrzej / Theriot, Edward C / Sabir, Meeshal J / Baeshen, Mohammad N / Hajarah, Nahid H / Baeshen, Nabih A / Sabir, Jamal S / Jansen, Robert K

    Protist

    2017  Volume 168, Issue 1, Page(s) 48–70

    Abstract: Several lineages of raphe-bearing diatoms possess a "stauros," which is a transverse, usually thickened area free of pores across the center of the valve. It has been suggested that this structure has evolved several times across the raphid diatoms, but ... ...

    Abstract Several lineages of raphe-bearing diatoms possess a "stauros," which is a transverse, usually thickened area free of pores across the center of the valve. It has been suggested that this structure has evolved several times across the raphid diatoms, but we have noticed similarities beyond the stauros between two marine genera-Craspedostauros and Staurotropis-in the structure of their pore occlusions. We have isolated, cultured and extracted DNA from several strains of both genera to infer the phylogenetic relationship between these taxa, as well as test the suggested relationship of Craspedostauros to Achnanthes and Mastogloia based on plastid morphology. DNA sequence data (nuclear-encoded rRNA SSU, plastid-encoded rbcL and psbC) suggest that, except for Mastogloia, these genera are closely-related, though not sister taxa. The DNA phylogeny also suggests that the Mastogloiales are not monophyletic, with clades containing Achnanthes and Craspedostauros sister to clades containing taxa in the Bacillariales. Using evidence from molecular and morphological data, we describe the following new taxa: Craspedostauros alyoubii and C. paradoxa from the Red Sea and Guam, respectively; Staurotropis khiyamii and S. americana from the Red Sea and the Gulf of Mexico, respectively; and Dreuhlago cuneata n. gen., n. sp. from Guam.
    MeSH term(s) Algal Proteins/genetics ; Diatoms/classification ; Diatoms/genetics ; Diatoms/ultrastructure ; Evolution, Molecular ; Microscopy, Electron, Scanning ; Phylogeny ; Sequence Analysis, DNA
    Chemical Substances Algal Proteins
    Language English
    Publishing date 2017
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2036014-9
    ISSN 1618-0941 ; 1434-4610
    ISSN (online) 1618-0941
    ISSN 1434-4610
    DOI 10.1016/j.protis.2016.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Molecular and Morphological Investigations of the Stauros-bearing, Raphid Pennate Diatoms (Bacillariophyceae): Craspedostauros E.J. Cox, and Staurotropis T.B.B. Paddock, and their Relationship to the Rest of the Mastogloiales

    Ashworth, Matt P / Andrzej Witkowski / Christopher S. Lobban / Edward C. Theriot / Jamal S. Sabir / Meeshal J. Sabir / Mohammad N. Baeshen / Nabih A. Baeshen / Nahid H. Hajarah / Robert K. Jansen

    Protist. 2017 Feb., v. 168, no. 1

    2017  

    Abstract: Several lineages of raphe-bearing diatoms possess a “stauros,” which is a transverse, usually thickened area free of pores across the center of the valve. It has been suggested that this structure has evolved several times across the raphid diatoms, but ... ...

    Abstract Several lineages of raphe-bearing diatoms possess a “stauros,” which is a transverse, usually thickened area free of pores across the center of the valve. It has been suggested that this structure has evolved several times across the raphid diatoms, but we have noticed similarities beyond the stauros between two marine genera—Craspedostauros and Staurotropis—in the structure of their pore occlusions. We have isolated, cultured and extracted DNA from several strains of both genera to infer the phylogenetic relationship between these taxa, as well as test the suggested relationship of Craspedostauros to Achnanthes and Mastogloia based on plastid morphology. DNA sequence data (nuclear-encoded rRNA SSU, plastid-encoded rbcL and psbC) suggest that, except for Mastogloia, these genera are closely-related, though not sister taxa. The DNA phylogeny also suggests that the Mastogloiales are not monophyletic, with clades containing Achnanthes and Craspedostauros sister to clades containing taxa in the Bacillariales. Using evidence from molecular and morphological data, we describe the following new taxa: Craspedostauros alyoubii and C. paradoxa from the Red Sea and Guam, respectively; Staurotropis khiyamii and S. americana from the Red Sea and the Gulf of Mexico, respectively; and Dreuhlago cuneata n. gen., n. sp. from Guam.
    Keywords Achnanthes ; DNA ; Mastogloia ; monophyly ; new species ; nucleotide sequences ; pastures ; ribosomal RNA ; Guam ; Gulf of Mexico ; Red Sea
    Language English
    Dates of publication 2017-02
    Size p. 48-70.
    Publishing place Elsevier GmbH
    Document type Article
    ZDB-ID 2036014-9
    ISSN 1618-0941 ; 1434-4610
    ISSN (online) 1618-0941
    ISSN 1434-4610
    DOI 10.1016/j.protis.2016.11.001
    Database NAL-Catalogue (AGRICOLA)

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  3. Book ; Thesis: Do bleaching gels affect the stability of the masking and caries-arresting effects of caries infiltration - in vitro

    Jansen, Ellen Elisabeth

    2021  

    Author's details vorgelegt von Ellen Elisabeth Jansen geb. Hartmann
    Language German
    Size Seiten 4011-4021, Illustrationen, Diagramme
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2021
    Note Die Dissertation bestent aus einem Aufsatz, der zuvor in der Zeitschrift "Clinical oral investigations" (2021(25/6):4011-4021) veröffentlicht wurde; DOI: 10.1007/s00784-020-03732-4
    HBZ-ID HT020970599
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2021 D 511 order for loan Magazin

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  4. Article: [No title information]

    Maree, Johanna E / Jansen van Rensburg, Jacoba J M / Hadebe, Sizakele N

    Canadian oncology nursing journal = Revue canadienne de nursing oncologique

    2024  Volume 34, Issue 1, Page(s) 22–27

    Title translation S’occuper des patients atteints de cancer : l’expérience d’infirmières et d’infirmiers d’Afrique du Sud travaillant en soins aigus.
    Language French
    Publishing date 2024-01-01
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2033138-1
    ISSN 2368-8076 ; 1181-912X
    ISSN (online) 2368-8076
    ISSN 1181-912X
    DOI 10.5737/2368807634122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Caring for cancer patients in acute cancer care settings: Voices of South African nurses.

    Maree, Johanna E / Jansen van Rensburg, Jacoba J M / Hadebe, Sizakele N

    Canadian oncology nursing journal = Revue canadienne de nursing oncologique

    2024  Volume 34, Issue 1, Page(s) 16–21

    Abstract: Little is known about the experience of nurses in Africa caring for cancer patients. This study was undertaken to provide a straightforward description of the experiences of South African nurses caring for patients in acute cancer care settings. ... ...

    Abstract Little is known about the experience of nurses in Africa caring for cancer patients. This study was undertaken to provide a straightforward description of the experiences of South African nurses caring for patients in acute cancer care settings. Purposive sampling selected 20 nurses with whom there were in-depth interviews. Most of the participants were female registered oncology nurses with more than five years' experience. Three themes were identified: defining the cancer nursing experience, the challenges experienced in caring for cancer patients, and challenges imposed by the healthcare system. Most of the participants believed they were called by God to care for cancer patients. However, the challenges they experienced led to guilt feelings and believing the care they provided was insufficient. They were subjected to workplace violence, missed the support from senior nursing management, and displayed signs of burnout. Addressing these challenges could limit their emotional distress and prevent burnout.
    Language English
    Publishing date 2024-01-01
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2033138-1
    ISSN 2368-8076 ; 1181-912X
    ISSN (online) 2368-8076
    ISSN 1181-912X
    DOI 10.5737/2368807634116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Advancements in kidney organoids and tubuloids to study (dys)function.

    Dilmen, E / Orhon, I / Jansen, J / Hoenderop, J G J

    Trends in cell biology

    2023  Volume 34, Issue 4, Page(s) 299–311

    Abstract: The rising prevalence of kidney diseases urges the need for novel therapies. Kidney organoids and tubuloids are advanced in vitro models and have recently been described as promising tools to study kidney (patho)physiology. Recent developments have shown ...

    Abstract The rising prevalence of kidney diseases urges the need for novel therapies. Kidney organoids and tubuloids are advanced in vitro models and have recently been described as promising tools to study kidney (patho)physiology. Recent developments have shown their application in disease modeling, drug screening, and nephrotoxicity. These applications rely on their ability to mimic (dys)function in vitro including endocrine activity and drug, electrolyte, and water transport. This review provides an overview of these emerging kidney models and focuses on the most recent developments that utilize their functional capabilities. In addition, we cover current limitations and provide future perspectives for this rapidly evolving field, including what these functional properties mean for translational and personalized medicine now and in the future.
    MeSH term(s) Humans ; Kidney ; Organoids
    Language English
    Publishing date 2023-10-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 30122-x
    ISSN 1879-3088 ; 0962-8924
    ISSN (online) 1879-3088
    ISSN 0962-8924
    DOI 10.1016/j.tcb.2023.09.005
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    Zs.MG 25: Show issues
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    Zs.A 3410: Show issues Location:
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  7. Article ; Online: Reading Difficulties in Individuals with Homonymous Visual Field Defects: A Systematic Review of Reported Interventions.

    Tol, S / de Haan, G A / Postuma, E M J L / Jansen, J L / Heutink, J

    Neuropsychology review

    2024  

    Abstract: ... paragraph reading tasks with a time-based outcome measure (e.g. words per minute). Future research ...

    Abstract Reading difficulties are amongst the most commonly reported problems in individuals with homonymous visual field defects (HVFDs). To be able to provide guidance for healthcare professionals considering offering reading training, researchers in this field and interested individuals with HVFDs, this systematic review aims to (1) provide an overview of the contextual and intervention characteristics of all published HVFD interventions and (2) generate insights into the different reading outcome measures that these studies adopted. A search on PsycINFO, MEDLINE and Web of Science was conducted up to February 2, 2023. All intervention studies for HVFD in which reading was measured were included. Data was collected about the intervention type, session duration, number of sessions, the intensity, duration, circumstance of the interventions, country in which the intervention was studied and reading measures. Sixty records are included, describing 70 interventions in total of which 21 are specifically reading interventions. Overall, adjusted saccadic behaviour interventions occur most in the literature. A wide range within all intervention characteristics was observed. Forty-nine records reported task-performance reading measures, and 33 records reported self-reported reading measures. The majority of task-performance measures are based on self-developed paragraph reading tasks with a time-based outcome measure (e.g. words per minute). Future research could benefit from making use of validated reading tests, approaching the measurement of reading mixed-methods and providing participants the possibility to supply outcomes relevant to them.
    Language English
    Publishing date 2024-04-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1062572-0
    ISSN 1573-6660 ; 1040-7308
    ISSN (online) 1573-6660
    ISSN 1040-7308
    DOI 10.1007/s11065-024-09636-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3116: Show issues Location:
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  8. Article: SUMO control of centromere homeostasis.

    van den Berg, Sebastiaan J W / Jansen, Lars E T

    Frontiers in cell and developmental biology

    2023  Volume 11, Page(s) 1193192

    Abstract: Centromeres are unique chromosomal loci that form the anchorage point for the mitotic spindle during mitosis and meiosis. Their position and function are specified by a unique chromatin domain featuring the histone H3 variant CENP-A. While typically ... ...

    Abstract Centromeres are unique chromosomal loci that form the anchorage point for the mitotic spindle during mitosis and meiosis. Their position and function are specified by a unique chromatin domain featuring the histone H3 variant CENP-A. While typically formed on centromeric satellite arrays, CENP-A nucleosomes are maintained and assembled by a strong self-templated feedback mechanism that can propagate centromeres even at non-canonical sites. Central to the epigenetic chromatin-based transmission of centromeres is the stable inheritance of CENP-A nucleosomes. While long-lived at centromeres, CENP-A can turn over rapidly at non-centromeric sites and even erode from centromeres in non-dividing cells. Recently, SUMO modification of the centromere complex has come to the forefront as a mediator of centromere complex stability, including CENP-A chromatin. We review evidence from different models and discuss the emerging view that limited SUMOylation appears to play a constructive role in centromere complex formation, while polySUMOylation drives complex turnover. The deSUMOylase SENP6/Ulp2 and the proteins segregase p97/Cdc48 constitute the dominant opposing forces that balance CENP-A chromatin stability. This balance may be key to ensuring proper kinetochore strength at the centromere while preventing ectopic centromere formation.
    Language English
    Publishing date 2023-04-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2023.1193192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Turnover intention of foreign trained physicians in German rehabilitation facilities-a quantitative study.

    Jansen, Eva / Schmidt, Johanna / Marquardt, Manuela

    BMC health services research

    2024  Volume 24, Issue 1, Page(s) 402

    Abstract: Background: Germany's medical specialist shortage is an acute challenge, especially in the rehabilitation segment. One countermeasure is to recruit foreign trained physicians (FTP), but the high turnover of FTP is a burden on the departments that train ... ...

    Abstract Background: Germany's medical specialist shortage is an acute challenge, especially in the rehabilitation segment. One countermeasure is to recruit foreign trained physicians (FTP), but the high turnover of FTP is a burden on the departments that train them and integrate them professionally. Preliminary research showed that currently one in three physician positions in German Pension Insurance (DRV) contract facilities is filled by FTP.This paper examines factors related to turnover intention of FTP in German rehabilitative departments.
    Methodology: In spring 2022, we surveyed FTP across all inpatient and outpatient rehabilitation departments under the German Pension Insurance, using a two-stage cross-sectional approach. We conducted an online survey of FTP and developed a specialized questionnaire that captured sociodemographic, occupation related and professional biographical data, turnover intention, satisfaction, difficulties with professional integration and departmental structural characteristics. To analyze retention within the rehabilitation field, we used a measure of turnover intention, taking into account the direction of potential turnover, residency requirements and considerations of returning to the rehabilitation field. The data was evaluated in a subgroup analysis comparing FTP with and without turnover intention using Fisher's exact tests.
    Results: The sample includes n = 145 FTP, 119 stating no turnover intention and 27 with turnover intention. More than half of FTP with turnover intention wished to move to an acute care hospital. FTP with turnover intention are comparatively younger and came to Germany and were employed in the rehabilitation departments more recently, indicating an earlier career stage. Besides, career-related and regional factors show the strongest relation to turnover intention.
    Discussion and conclusion: The results reveal a group of "established FTP" whose professional integration has been successfully completed. FTP with turnover intention are comparatively younger, career-oriented physicians for whom work in a rehabilitative facility is a career springboard to gain a foothold in acute care clinics. A limitation is that FTP with turnover intention are difficult to reach and may be underrepresented in our sample.
    MeSH term(s) Humans ; Intention ; Job Satisfaction ; Foreign Medical Graduates ; Physicians ; Rehabilitation Centers ; Personnel Turnover ; Surveys and Questionnaires
    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-024-10902-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Bevacizumab Treatment for Patients with

    Douwes, Jules P J / Hensen, Erik F / Jansen, Jeroen C / Gelderblom, Hans / Schopman, Josefine E

    Cancers

    2024  Volume 16, Issue 8

    Abstract: 1) Background: ...

    Abstract (1) Background:
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16081479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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