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  1. Article ; Online: Estimating the effects of preventive and weight-management interventions on the prevalence of childhood obesity in England: a modelling study.

    Russell, Simon J / Mytton, Oliver T / Viner, Russell M

    The Lancet. Public health

    2023  Volume 8, Issue 11, Page(s) e878–e888

    Abstract: Background: The effects of the systematic delivery of treatments for obesity are unknown. We aimed to estimate the potential effects on the prevalence of childhood obesity of systematically offering preventive and treatment interventions to eligible ... ...

    Abstract Background: The effects of the systematic delivery of treatments for obesity are unknown. We aimed to estimate the potential effects on the prevalence of childhood obesity of systematically offering preventive and treatment interventions to eligible children in England, based on weight or health status.
    Methods: For this modelling study, we developed a cross-sectional simulation model of the child and young adult population in England using data from multiple years of the Health Survey of England conducted between Jan 1, 2010, and Dec 31, 2019. Individuals were assessed for eligibility via age, BMI, and medical complications. Weight status was defined based on clinical criteria used by the UK National Institute of Health and Care Excellence. Published systematic reviews were used to estimate effect sizes for treatments, uptake, and completion for each weight-management tier. We used all available evidence, including evidence from studies that showed an unfavourable effect. We estimated the effects of two systematic approaches: a staged approach, in which children and young people were simultaneously given the most intensive treatment for which they were eligible, and a stepped approach, in which each management tier was applied sequentially, with additive effects. The primary outcomes were estimated prevalence of clinical obesity, defined as a BMI ≥98th centile on the UK90 growth chart, and difference in comparison with the estimated baseline prevalence.
    Findings: 18 080 children and young people were included in the analytical sample. Baseline prevalence of clinical obesity was estimated to be 11·2% (95% CI 10·5 to 11·8) for children and young people aged 2-18 years. In modelling, we estimated absolute decreases in the prevalence of obesity of 0·9% (95% CI 0·1 to 1·8) for universal, preventive interventions; 0·2% (0·1 to 0·4) for interventions within a primary-care setting; 1·0% (0·1 to 2·1) for community and lifestyle interventions; 0·2% (0·0 to 0·4) for pharmaceutical interventions; and 0·4% (0·1 to 0·7) for surgical interventions. Staged care was estimated to result in an absolute decrease in the prevalence of obesity of 1·3% (-0·3 to 2·4) and stepped care was estimated to lead to an absolute decrease of 2·4% (0·1 to 4·8).
    Interpretation: Although individual effect sizes for prevention and treatment interventions were small, when delivered at scale across England, these interventions have the potential to meaningfully contribute to reducing the prevalence of childhood obesity.
    Funding: UK National Institute for Health and Care Research.
    MeSH term(s) Young Adult ; Child ; Humans ; Adolescent ; Pediatric Obesity/epidemiology ; Pediatric Obesity/prevention & control ; Cross-Sectional Studies ; Prevalence ; Exercise ; England/epidemiology
    Language English
    Publishing date 2023-10-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2468-2667
    ISSN (online) 2468-2667
    DOI 10.1016/S2468-2667(23)00216-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Daily antigen testing to reduce disruption when schools return.

    Viner, Russell M / Koirala, Archana

    Lancet (London, England)

    2021  Volume 398, Issue 10307, Page(s) 1196–1197

    MeSH term(s) COVID-19 ; Humans ; Schools
    Language English
    Publishing date 2021-09-14
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)02092-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: NHS must prioritise health of children and young people.

    Viner, Russell M

    BMJ (Clinical research ed.)

    2018  Volume 360, Page(s) k1116

    MeSH term(s) Adolescent ; Age Factors ; Child ; Child, Preschool ; Health Expenditures ; Health Priorities ; Humans ; Infant ; Infant, Newborn ; State Medicine/economics ; State Medicine/organization & administration ; United Kingdom ; Young Adult
    Language English
    Publishing date 2018--14
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.k1116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Approach to a child or young person with concerns about excess weight.

    Mytton, Oliver T / Nicholls, Dasha / Saxena, Sonia / Viner, Russell M

    BMJ (Clinical research ed.)

    2023  Volume 380, Page(s) e074255

    MeSH term(s) Child ; Humans ; Adolescent ; Body Weight ; Weight Gain ; Body Mass Index
    Language English
    Publishing date 2023-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj-2022-074255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Exploring predictors and moderators of response to multimodal obesity treatment in children.

    Aman-Braaksma, Simone / Croker, Helen / Viner, Russell M / Nicholls, Dasha

    Archives of disease in childhood

    2023  Volume 108, Issue 5, Page(s) 405–409

    Abstract: Objective: The aim of this study was to determine whether specific psychological factors influence intervention effects for children with severe obesity in a clinical setting.: Design: Secondary analyses of data about attention deficit/hyperactivity ... ...

    Abstract Objective: The aim of this study was to determine whether specific psychological factors influence intervention effects for children with severe obesity in a clinical setting.
    Design: Secondary analyses of data about attention deficit/hyperactivity disorder (ADHD) characteristics, body satisfaction, social and emotional functioning, and the primary outcome, change in body mass index (BMI), were available for 41 out of 72 children and their families randomised to family-based behavioural treatment over 6 months or waiting list control. Regression analyses, with an interaction term for treatment condition, were performed to explore baseline factors and moderators of outcome.
    Results: Parents reporting their child's emotional well-being as high and high maternal education significantly predicted less weight loss for the total sample, with no effect of ethnicity, age, sex or baseline BMI. Children's social functioning was a significant moderator of treatment effect; children with high social function showed a decrease in BMI after 6 months of therapy (R
    Conclusions: These preliminary findings suggest directions for development of tailored obesity programmes. Professionals engaged in treatment of childhood obesity should consider a child's emotional and social functioning when considering group obesity intervention, as well as the risks of no intervention.
    MeSH term(s) Child ; Humans ; Attention Deficit Disorder with Hyperactivity/psychology ; Behavior Therapy ; Body Mass Index ; Parents/psychology ; Pediatric Obesity/therapy
    Language English
    Publishing date 2023-02-06
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2022-325013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Kawasaki-like disease: emerging complication during the COVID-19 pandemic.

    Viner, Russell M / Whittaker, Elizabeth

    Lancet (London, England)

    2020  Volume 395, Issue 10239, Page(s) 1741–1743

    MeSH term(s) Betacoronavirus ; COVID-19 ; Child ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)31129-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19 in children and young people.

    Snape, Matthew D / Viner, Russell M

    Science (New York, N.Y.)

    2020  Volume 370, Issue 6514, Page(s) 286–288

    MeSH term(s) Adolescent ; COVID-19 ; Child ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Risk ; Schools ; United Kingdom/epidemiology ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.abd6165
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  8. Article ; Online: Is it possible to model the impact of calorie-reduction interventions on childhood obesity at a population level and across the range of deprivation: Evidence from the Avon Longitudinal Study of Parents and Children (ALSPAC).

    Russell, Simon J / Hope, Steven / Croker, Helen / Packer, Jessica / Viner, Russell M

    PloS one

    2022  Volume 17, Issue 1, Page(s) e0263043

    Abstract: Background: Simulated interventions using observational data have the potential to inform policy and public health interventions where randomised controlled trials are not feasible. National childhood obesity policy is one such area. Overweight and ... ...

    Abstract Background: Simulated interventions using observational data have the potential to inform policy and public health interventions where randomised controlled trials are not feasible. National childhood obesity policy is one such area. Overweight and obesity are primarily caused by energy-rich and low-nutrient diets that contribute to a positive net energy imbalance. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC), we investigated whether causal modelling techniques could be applied to simulate the potential impact of policy-relevant calorie-reduction interventions on population prevalence and inequalities in obesity in childhood.
    Methods: Predicted probabilities of obesity at age 11 (UK90 cut offs) were estimated from logistic marginal structural models (MSM) accounting for observed calorie consumption at age 7 and confounding, overall and by maternal occupational social class. A series of population intervention scenarios were modelled to simulate daily calorie-reduction interventions that differed in effectiveness, targeting mechanism and programme uptake level.
    Results: The estimated effect of maternal social class on obesity after accounting for confounding and observed calorie intake was provided by the controlled direct effect (CDE), in which, 18.3% of children were living with obesity at age 11 years,. A universal simulation to lower median intake to the estimated average requirement (EAR) (a 6.1% reduction in daily calories) with 75% uptake reduced overall obesity prevalence by 0.6%; there was little impact on inequalities. A targeted intervention to limit consumption to the EAR for children with above average intake reduced population obesity prevalence at 11 years by 1.5% but inequalities remained broadly unchanged. A targeted intervention for children of low-income families reduced prevalence by 0.7% and was found to slightly reduce inequalities.
    Conclusions: MSMs allow estimation of effects of simulated calorie-reduction interventions on childhood obesity prevalence and inequalities, although estimates are limited by the accuracy of reported calorie intake. Further work is needed to understand causal pathways and opportunities for intervention. Nevertheless, simulated intervention techniques have promise for informing national policy where experimental data are not available.
    MeSH term(s) Adult ; Caloric Restriction ; Child ; Energy Intake ; Female ; Humans ; Longitudinal Studies ; Male ; Models, Biological ; Pediatric Obesity/epidemiology
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0263043
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  9. Article ; Online: From crisis to opportunity: parents and schools can come together to prioritise student health and well-being.

    Bonell, Christopher / Sundaram, Neisha / Viner, Russell M

    Archives of disease in childhood

    2021  Volume 107, Issue 3, Page(s) e5

    MeSH term(s) COVID-19/epidemiology ; Child Health ; Humans ; Pandemics ; Parents/psychology ; SARS-CoV-2 ; School Health Services ; Schools ; Students/psychology ; Trust
    Language English
    Publishing date 2021-07-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2021-322511
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  10. Article ; Online: Impact of the COVID-19 pandemic on the clinical management trends for acute appendicitis among the under-25s: a retrospective study.

    Faitna, Puji / Harwood, Rachel / Kenny, Simon E / Viner, Russell M / Aylin, Paul P / Hargreaves, Dougal S / Bottle, Alex

    Archives of disease in childhood

    2024  Volume 109, Issue 4, Page(s) 339–346

    Abstract: Objective: To describe the COVID-19 pandemic's impact on acute appendicitis management on children and young people (CYP).: Design: Retrospective cohort study.: Setting: All English National Health Service hospitals.: Patients: Acute ... ...

    Abstract Objective: To describe the COVID-19 pandemic's impact on acute appendicitis management on children and young people (CYP).
    Design: Retrospective cohort study.
    Setting: All English National Health Service hospitals.
    Patients: Acute appendicitis admissions (all, simple, complex) by CYP (under-5s, 5-9s, 10-24s).
    Exposure: Study pandemic period: February 2020-March 2021. Comparator pre-pandemic period: February 2015-January 2020.
    Main outcome measures: Monthly appendicectomy and laparoscopic appendicectomy rate trends and absolute differences between pandemic month and the pre-pandemic average. Proportions of appendicitis admissions comprising complex appendicitis by hospital with or without specialist paediatric centres were compared.
    Results: 101 462 acute appendicitis admissions were analysed. Appendicectomy rates fell most in April 2020 for the 5-9s (-18.4% (95% CI -26.8% to -10.0%)) and 10-24s (-28.4% (-38.9% to -18.0%)), driven by reductions in appendicectomies for simple appendicitis. This was equivalent to -54 procedures (-68.4 to -39.6) and -512 (-555.9 to -467.3) for the 5-9s and 10-24s, respectively. Laparoscopic appendicectomies fell in April 2020 for the 5-9s (-15.5% (-23.2% to -7.8%)) and 10-24s (-44.8% (-57.9% to -31.6%) across all types, which was equivalent to -43 (-56.1 to 30.3) and -643 (-692.5 to -593.1) procedures for the 5-9s and 10-24s, respectively. A larger proportion of complex appendicitis admissions were treated within trusts with specialist paediatric centres during the pandemic.
    Conclusions: For CYP across English hospitals, a sharp recovery followed a steep reduction in appendicectomy rates in April 2020, due to concerns with COVID-19 transmission. This builds on smaller-sized studies reporting the immediate short-term impacts.
    MeSH term(s) Humans ; Child ; Adolescent ; COVID-19/epidemiology ; Retrospective Studies ; Pandemics ; Appendicitis/epidemiology ; Appendicitis/surgery ; State Medicine ; Acute Disease
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2023-326313
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