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  1. Article: Carcinoma of the extrahepatic bile ducts.

    El-Domeiri, A A / Brasfield, R D / O'quinn, J L

    Annals of surgery

    2007  Volume 169, Issue 4, Page(s) 525–532

    Language English
    Publishing date 2007-06-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/00000658-196904000-00008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Treatment of hepatic metastases in cancer of the colon and rectum. A preliminary report.

    El-Domeiri, A A

    Cancer

    1980  Volume 45, Issue 9, Page(s) 2245–2248

    Abstract: Treatment of hepatic metastases in 31 patients with cancer of the colon and rectum consisted of wedge resection or partial hepatectomy in 2; systemic chemotherapy in 13; chemotherapy infusion of the hepatic artery in 9; and chemotherapy infusion combined ...

    Abstract Treatment of hepatic metastases in 31 patients with cancer of the colon and rectum consisted of wedge resection or partial hepatectomy in 2; systemic chemotherapy in 13; chemotherapy infusion of the hepatic artery in 9; and chemotherapy infusion combined with intermittent arterial occlusion in 7. Patients were not randomized with regard to type of treatment, yet the age and sex distribution of these patients was similar in the three groups receiving chemotherapy. One patient treated by resection of a solitary hepatic lesion had been living with no evidence of disease for over three years. None of the patients who received systemic chemotherapy exhibited evidence of objective response. Four of 9 patients who received chemotherapy infusion and 4 of 7 who received a combination of arterial occlusion and chemotherapy infusion survived for periods ranging from 18 to 32 months. Clinical evaluation of individual patients indicated that those having metastases confined to the liver (Stages II and III) who received intermittent arterial occlusion and chemotherapy infusion enjoyed longer periods of objective response and experienced fewer complications than did those treated by chemotherapy infusion alone.
    MeSH term(s) Adenocarcinoma/pathology ; Adolescent ; Adult ; Aged ; Antineoplastic Agents/therapeutic use ; Child ; Child, Preschool ; Colonic Neoplasms/pathology ; Embolization, Therapeutic ; Female ; Hepatectomy ; Humans ; Infusions, Intra-Arterial ; Liver Neoplasms/drug therapy ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Prognosis ; Rectal Neoplasms/pathology ; Time Factors
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 1980-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/1097-0142(19800501)45:9<2245::aid-cncr2820450904>3.0.co;2-l
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Midline cancer of the floor of the mouth: role of suprahyoid dissection.

    El-Domeiri, A A

    The British journal of surgery

    1979  Volume 66, Issue 7, Page(s) 453–455

    Abstract: Of 37 patients with squamous cell carcinoma of the floor of the mouth seen during a 5-year period, 28 were treated primarily by surgery. Ten of the 28 patients presented with midline cancers measuring between 1.0 and 3 cm (T1 and T2). Three of these ... ...

    Abstract Of 37 patients with squamous cell carcinoma of the floor of the mouth seen during a 5-year period, 28 were treated primarily by surgery. Ten of the 28 patients presented with midline cancers measuring between 1.0 and 3 cm (T1 and T2). Three of these patients had local excision only. Metastases to the submandibular lymph nodes later occurred in 1 of these 3 patients. The remaining 7 patients with midline lesions had wide excision of the tumour, marginal resection of the mandible and bilateral suprahyoid node dissection. Of these 7 patients 4 remained free of disease for periods ranging between 2 and 5 years. Two of these had lymph node metastases. These results suggest that en bloc excision of relatively small midline cancers (i.e. not exceeding 2 cm (T1) in largest diameter) with bilateral suprahoid node dissection gives effective control of these lesions.
    MeSH term(s) Adult ; Aged ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Female ; Humans ; Hyoid Bone ; Lymphatic Metastasis ; Male ; Methods ; Middle Aged ; Mouth Floor ; Mouth Neoplasms/pathology ; Mouth Neoplasms/surgery ; Neoplasm Staging ; Submandibular Gland
    Language English
    Publishing date 1979-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2985-3
    ISSN 0007-1323 ; 0263-1202 ; 1355-7688
    ISSN 0007-1323 ; 0263-1202 ; 1355-7688
    DOI 10.1002/bjs.1800660703
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Immune response and non-specific immunotherapy in melanoma.

    El-Domeiri, A A

    Annals of the Royal College of Surgeons of England

    1978  Volume 60, Issue 2, Page(s) 117–120

    Abstract: Tumour-associated antigens and specific immune response to these antigens have been clearly demonstrated in patients with melanoma. Impaired cellular immune reactions are evident in patients with progressive and disseminated disease. Immunotherapy is ... ...

    Abstract Tumour-associated antigens and specific immune response to these antigens have been clearly demonstrated in patients with melanoma. Impaired cellular immune reactions are evident in patients with progressive and disseminated disease. Immunotherapy is used to heighten the host resistance and hence prevent recurrence and spread of the tumour. BCG vaccine has been used to produce nonspecific stimulation of the immune system. Preliminary evaluation of the effect of adjuvant systemic BCG therapy suggests that the treatment may have a beneficial effect on patients with early melanoma.
    MeSH term(s) Antibody Formation ; BCG Vaccine/therapeutic use ; Humans ; Immunity, Cellular ; Melanoma/immunology ; Melanoma/therapy ; Neoplasm Metastasis ; Skin Neoplasms/therapy ; Skin Tests
    Chemical Substances BCG Vaccine
    Language English
    Publishing date 1978-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
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  5. Article: Delayed hypersensitivity reaction: its relation to tumor spread and prognosis.

    El-Domeiri, A A

    Surgery annual

    1977  Volume 9, Page(s) 343–350

    MeSH term(s) Antigens, Neoplasm ; Dinitrochlorobenzene ; Humans ; Hypersensitivity, Delayed ; Immunity, Cellular ; Neoplasms/immunology ; Prognosis ; Recurrence ; Skin Tests
    Chemical Substances Antigens, Neoplasm ; Dinitrochlorobenzene (GE3IBT7BMN)
    Language English
    Publishing date 1977
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391342-9
    ISSN 0081-9638
    ISSN 0081-9638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Repair of abdominal and thoracic wall defects by bovine fascia (ox fascia).

    El-Domeiri, A A

    Archives of surgery (Chicago, Ill. : 1960)

    1976  Volume 111, Issue 2, Page(s) 172–174

    Abstract: Sheets of heterologous fascia (bovine fascia) were used to close large defects of the thoracic and abdominal wall in four patients with malignant neoplasms. The material was well tolerated by the body and provided adequate protection and support to the ... ...

    Abstract Sheets of heterologous fascia (bovine fascia) were used to close large defects of the thoracic and abdominal wall in four patients with malignant neoplasms. The material was well tolerated by the body and provided adequate protection and support to the underlying viscera. Although the fascial graft was not covered by skin flaps in two patients with abdominal wall defects, it became readily incorporated into granulation tissue that was receptive to split thickness skin grafts. The fascia was used successfully in a contaminated field and control of active infection was possible without removing the graft. These findings demonstrate that heterologous fascia is particularly useful under conditions that are not suitable for the use of synthetic materials.
    MeSH term(s) Abdominal Neoplasms/surgery ; Adult ; Animals ; Breast Neoplasms/surgery ; Cattle ; Fascia/transplantation ; Female ; Humans ; Male ; Middle Aged ; Penile Neoplasms/surgery ; Scrotum ; Testicular Neoplasms/surgery ; Thoracic Neoplasms/surgery ; Transplantation, Heterologous/methods
    Language English
    Publishing date 1976-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80055-7
    ISSN 1538-3644 ; 0004-0010 ; 0096-6908 ; 0272-5533
    ISSN (online) 1538-3644
    ISSN 0004-0010 ; 0096-6908 ; 0272-5533
    DOI 10.1001/archsurg.1976.01360200078014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A method of intermittent occlusion and chemotherapy infusion of the hepatic artery.

    El-Domeiri, A A

    Surgery, gynecology & obstetrics

    1976  Volume 143, Issue 1, Page(s) 107–109

    Abstract: A method of intermittent occlusion of the hepatic artery and chemotherapy infusion has been developed using a catheter introduced into the hepatic artery, with interruption of the blood flow accomplished by inflation of the balloon. This method is less ... ...

    Abstract A method of intermittent occlusion of the hepatic artery and chemotherapy infusion has been developed using a catheter introduced into the hepatic artery, with interruption of the blood flow accomplished by inflation of the balloon. This method is less likely than ligation of the hepatic artery to produce massive liver necrosis, and it ensures adequate perfusion of the tumor tissue with the chemotherapeutic agents.
    MeSH term(s) Antineoplastic Agents/administration & dosage ; Chemotherapy, Cancer, Regional Perfusion ; Heparin ; Hepatic Artery ; Humans ; Liver/blood supply ; Liver Neoplasms/therapy
    Chemical Substances Antineoplastic Agents ; Heparin (9005-49-6)
    Language English
    Publishing date 1976-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 5099-4
    ISSN 0039-6087
    ISSN 0039-6087
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  8. Article: Tumor spread and reactivity to DNCB: (2, 4 Dinitro-1 chlorobenzene) skin test.

    el-Domeiri, A A

    International surgery

    1972  Volume 57, Issue 8, Page(s) 617–619

    MeSH term(s) Adult ; Aged ; Breast Neoplasms/diagnosis ; Chlorine ; Colonic Neoplasms/diagnosis ; Female ; Head and Neck Neoplasms/diagnosis ; Humans ; Hypersensitivity, Delayed ; Lymphatic Metastasis ; Male ; Melanoma/diagnosis ; Middle Aged ; Neoplasm Metastasis ; Neoplasms/diagnosis ; Neoplasms/immunology ; Nitrobenzenes ; Prognosis ; Rectal Neoplasms/diagnosis ; Skin Tests
    Chemical Substances Nitrobenzenes ; Chlorine (4R7X1O2820)
    Language English
    Publishing date 1972-08
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 80343-1
    ISSN 0020-8868
    ISSN 0020-8868
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  9. Article: The question of recurrence and malignant transformation in Keratoacanthoma (molluscum sebaceum).

    el-Domeiri, A

    The Journal of the Egyptian Medical Association

    1971  Volume 54, Issue 1, Page(s) 68–73

    MeSH term(s) Aged ; Cell Transformation, Neoplastic ; Humans ; Keratoacanthoma/pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Skin Neoplasms/pathology
    Language English
    Publishing date 1971
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 444493-0
    ISSN 0013-2411
    ISSN 0013-2411
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  10. Article: Effect of infusion chemotherapy and hepatic artery ligation on normal liver: experimental study in the cat.

    Delk, S / El-Domeiri, A A

    Journal of surgical oncology

    1979  Volume 11, Issue 1, Page(s) 39–44

    Abstract: The effects of arterial infusion with chemotherapy alone or in combination with hepatic artery ligation on the normal liver of the cat were studied. Early in the course of treatment cats receiving chemotherapy infusion only appeared sicker than animals ... ...

    Abstract The effects of arterial infusion with chemotherapy alone or in combination with hepatic artery ligation on the normal liver of the cat were studied. Early in the course of treatment cats receiving chemotherapy infusion only appeared sicker than animals in other groups. Yet only 1 of 5 cats was dead at 12 weeks. In contrast, 4 of 6 animals that had hepatic artery ligation and chemotherapy infusion, and 3 of 6 that had ligation of the hepatic artery only, died during the same period of follow-up. Progressive liver damage after dearterialization accounted for the high mortality rate. Histologic examination of liver biopsies taken from animals in these latter groups revealed marked destruction of the parenchyma. These changes were more extensive in animals treated by a combination of hepatic artery ligation and chemotherapy infusion. To avoid the injurious effects of permanent interruption of the hepatic arterial flow on normal liver tissue an alternative method of hepatic dearterialization is currently under investigation.
    MeSH term(s) Animals ; Cats ; Female ; Fluorouracil/administration & dosage ; Fluorouracil/adverse effects ; Hepatic Artery/physiology ; Hepatic Artery/surgery ; Humans ; Infusions, Intra-Arterial ; Ligation/adverse effects ; Liver/drug effects ; Liver/pathology ; Liver/physiology ; Liver Neoplasms/therapy ; Male
    Chemical Substances Fluorouracil (U3P01618RT)
    Language English
    Publishing date 1979
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.2930110108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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