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  1. Article: Chest Pain in a Psychiatric Patient Due to Clozapine-Induced Myopericarditis.

    Laws, James L / Kim, Esther / Hung, Rebecca / Lindenfeld, JoAnn / Gupta, Richa

    Case reports in cardiology

    2021  Volume 2021, Page(s) 6067652

    Abstract: Drug-induced myocarditis is a rare, but underrecognized complication of clozapine therapy for schizophrenia. We present a case of clozapine-induced myocarditis with recovery of cardiac function after drug cessation and summarize the literature to ... ...

    Abstract Drug-induced myocarditis is a rare, but underrecognized complication of clozapine therapy for schizophrenia. We present a case of clozapine-induced myocarditis with recovery of cardiac function after drug cessation and summarize the literature to highlight the variable presentation of this condition.
    Language English
    Publishing date 2021-12-24
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627627-6
    ISSN 2090-6412 ; 2090-6404
    ISSN (online) 2090-6412
    ISSN 2090-6404
    DOI 10.1155/2021/6067652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Morbidity and Mortality Among Adults Experiencing Homelessness Hospitalized With COVID-19.

    Cha, Susan / Henry, Ankita / Montgomery, Martha P / Laws, Rebecca L / Pham, Huong / Wortham, Jonathan / Garg, Shikha / Kim, Lindsay / Mosites, Emily

    The Journal of infectious diseases

    2021  Volume 224, Issue 3, Page(s) 425–430

    Abstract: People experiencing homelessness (PEH) are at higher risk for chronic health conditions, but clinical characteristics and outcomes for PEH hospitalized with coronavirus disease 2019 (COVID-19) are not known. We analyzed population-based surveillance data ...

    Abstract People experiencing homelessness (PEH) are at higher risk for chronic health conditions, but clinical characteristics and outcomes for PEH hospitalized with coronavirus disease 2019 (COVID-19) are not known. We analyzed population-based surveillance data of COVID-19-associated hospitalizations during 1 March to 31 May 2020. Two percent of the people hospitalized with COVID-19 for whom a housing status was recorded were homeless. Of 199 cases in the analytic sample, most were of racial/ethnic minority groups and had underlying health conditions. Clinical outcomes such as ICU admission, respiratory support including mechanical ventilation, and deaths were documented. Hispanic and non-Hispanic black persons accounted for most mechanical ventilation and deaths. Severe illness was common among persons experiencing homelessness who were hospitalized with COVID-19.
    MeSH term(s) Adolescent ; Adult ; Aged ; COVID-19/epidemiology ; COVID-19/mortality ; COVID-19/therapy ; Comorbidity ; Female ; Homeless Persons/statistics & numerical data ; Hospitalization/statistics & numerical data ; Humans ; Male ; Middle Aged ; Racial Groups/statistics & numerical data ; Severity of Illness Index ; Treatment Outcome ; United States/epidemiology ; Young Adult
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiab261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Risk factors for occupational heat-related illness among California workers, 2000-2017.

    Heinzerling, Amy / Laws, Rebecca L / Frederick, Matt / Jackson, Rebecca / Windham, Gayle / Materna, Barbara / Harrison, Robert

    American journal of industrial medicine

    2020  Volume 63, Issue 12, Page(s) 1145–1154

    Abstract: Background: As climate change increases global temperatures, heat-related morbidity and mortality are projected to rise. Outdoor workers and those who perform exertional tasks are particularly susceptible to heat-related illness (HRI). Using workers' ... ...

    Abstract Background: As climate change increases global temperatures, heat-related morbidity and mortality are projected to rise. Outdoor workers and those who perform exertional tasks are particularly susceptible to heat-related illness (HRI). Using workers' compensation data, we aimed to describe rates of occupational HRI in California and identify demographic and occupational risk factors to inform prevention efforts.
    Methods: We identified HRI cases during 2000-2017 in the California Workers' Compensation Information System (WCIS) using International Classification of Diseases Ninth and Tenth Revision codes, WCIS nature and cause of injury codes, and HRI keywords. We assigned industry and occupation codes using the NIOSH Industry and Occupation Computerized Coding System (NIOCCS). We calculated HRI rates by sex, age group, year, county, industry, and occupation, and estimated confidence intervals using generalized linear models.
    Results: We identified 15,996 HRI cases during 2000-2017 (6.0 cases/100,000 workers). Workers aged 16-24 years had the highest HRI rate (7.6) among age groups, and men (8.1) had a higher rate than women (3.5). Industry sectors with the highest HRI rates were Agriculture, Farming, Fishing, and Forestry (38.6), and Public Administration (35.3). Occupational groups with the highest HRI rates were Protective Services (56.6) and Farming, Fishing, and Forestry (36.6). Firefighters had the highest HRI rate (389.6) among individual occupations.
    Conclusions: Workers in certain demographic and occupational groups are particularly susceptible to HRI. Additional prevention efforts, including outreach and enforcement targeting high-risk groups, are needed to reduce occupational HRI. Workers' compensation data can provide timely information about temporal trends and risk factors for HRI.
    MeSH term(s) Adolescent ; Adult ; California/epidemiology ; Female ; Heat Stress Disorders/epidemiology ; Heat Stress Disorders/etiology ; Humans ; Industry/statistics & numerical data ; Male ; Middle Aged ; Occupational Diseases/epidemiology ; Occupational Diseases/etiology ; Occupational Exposure/adverse effects ; Occupational Exposure/statistics & numerical data ; Occupations/statistics & numerical data ; Risk Factors ; Workers' Compensation/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2020-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604538-8
    ISSN 1097-0274 ; 0271-3586
    ISSN (online) 1097-0274
    ISSN 0271-3586
    DOI 10.1002/ajim.23191
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  4. Article ; Online: Barriers to COVID-19 Prevention Measures Among People Experiencing Homelessness with Substance Use Disorder or Serious Mental Illness.

    Meehan, Ashley A / Jeffers, Alexiss / Barker, Jordan / Ray, Colleen M / Laws, Rebecca L / Fields, Victoria L / Miedema, Stephanie S / Cha, Susan / Cassell, Cynthia H / DiPietro, Barbara / Cary, Margaret / Yang, Maria / McLendon, Hedda / Marcus, Ruthanne / Mosites, Emily

    Journal of prevention (2022)

    2023  Volume 44, Issue 6, Page(s) 663–678

    Abstract: People experiencing homelessness (PEH) are at disproportionate risk of becoming infected and having severe illness from coronavirus disease 2019 (COVID-19), especially when residing in congregate settings like homeless shelters. Behavioral health ... ...

    Abstract People experiencing homelessness (PEH) are at disproportionate risk of becoming infected and having severe illness from coronavirus disease 2019 (COVID-19), especially when residing in congregate settings like homeless shelters. Behavioral health problems related to substance use disorder (SUD) and severe mental illness (SMI) may have created additional challenges for PEH to practice prevention measures like mask wearing, physical distancing, handwashing, and quarantine and isolation. The study objective was to understand the perceived barriers PEH face regarding COVID-19 non-pharmaceutical prevention strategies and identify recommendations for overcoming barriers. From August-October 2020, qualitative phone interviews with 50 purposively selected behavioral health professionals across the United States serving PEH with SUD or SMI were conducted. Professionals described that PEH faced barriers to prevention that were structural (e.g., access to necessary resources), behavioral (related to SUD or SMI), or related to the priority of other needs. Recommendations to overcome these barriers included providing free prevention resources (e.g., masks and hand sanitizer), providing education about importance of prevention strategies, and prioritizing access to stable housing. Interviews took place before COVID-19 vaccines were available, so barriers to vaccination are not included in this paper. Findings can help support tailored approaches during COVID-19 and future public health threats.
    MeSH term(s) Humans ; COVID-19 Vaccines ; COVID-19/prevention & control ; Substance-Related Disorders/epidemiology ; Mental Disorders/epidemiology ; Ill-Housed Persons
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-09-26
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2731-5541
    ISSN (online) 2731-5541
    DOI 10.1007/s10935-023-00739-x
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  5. Article ; Online: Strategies used by schools to tackle food insecurity and hunger: a qualitative enquiry in 15 Victorian schools.

    Lindberg, Rebecca / Cirone, Kathryn / Larkin, Laura / Ball, Kylie / Laws, Rachel / Margerison, Claire

    Australian and New Zealand journal of public health

    2022  Volume 46, Issue 4, Page(s) 444–449

    Abstract: Objective: Food insecurity is a threat to children's development and in Australia 13.5% of households experience food insecurity. Universal school food programs, however, are not provided nationally. Teachers and not-for-profit organisations have ... ...

    Abstract Objective: Food insecurity is a threat to children's development and in Australia 13.5% of households experience food insecurity. Universal school food programs, however, are not provided nationally. Teachers and not-for-profit organisations have instead mobilised to tackle hunger. The strategies used and their effects on students have limited empirical evidence. The aim of this study is to gain perspectives on the causes and consequences of children's food insecurity in schools and describe food security strategies adopted.
    Method: One hundred schools in Victoria, which participate in a not-for-profit lunch program provided by Eat Up were invited to take part in the study. Fifteen staff (including school principals and welfare officers) from 15 schools were recruited for semi-structured interviews.  Results: There was evidence that children experience adverse quantity, quality, social and psychological impacts of food insecurity whilst in school settings. Participants described employing multiple strategies including free meals (e.g. lunch, breakfast) and food (e.g. parcels) for food insecure students and their families. Conclusions and implications for public health: In our sample, multiple strategies were being employed by schools to reduce food insecurity, but there remains unmet need for additional wide-scale initiatives to address this critical issue and its causes and consequences.
    MeSH term(s) Child ; Food Insecurity ; Food Supply ; Humans ; Hunger ; Lunch ; Schools ; Victoria
    Language English
    Publishing date 2022-06-09
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1323548-5
    ISSN 1753-6405 ; 1326-0200
    ISSN (online) 1753-6405
    ISSN 1326-0200
    DOI 10.1111/1753-6405.13255
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  6. Article ; Online: Progress towards the UNAIDS 95-95-95 targets in the Fifth Botswana AIDS Impact Survey (BAIS V 2021): a nationally representative survey.

    Mine, Madisa / Stafford, Kristen A / Laws, Rebecca L / Marima, Reson / Lekone, Phenyo / Ramaabya, Dinah / Makhaola, Kgomotso / Patel, Hetal K / Mapondera, Prichard / Wray-Gordon, Floris / Agbakwuru, Chinedu / Okui, Lillian / Matroos, Susan / Onyadile, Eden / Ngidi, Julia / Abimiku, Alash'le / Bagapi, Khuteletso / Nkomo, Bornapate / Bodika, Stephane M /
    Kim, Kaylee J / Moloney, Mirna / Mitchell, Andrew / Ehoche, Akipu / Ussery, Faith L / Hong, Steven Y / Keipeile, Stella / Matlhaga, Matshelo / Mathumo, Rapetse / Selato, Robert / Charurat, Manhattan E / Voetsch, Andrew C

    The lancet. HIV

    2024  Volume 11, Issue 4, Page(s) e245–e254

    Abstract: Background: In 2014, UNAIDS set a goal to end the AIDS epidemic by achieving targets for the percentage of people living with HIV who were aware of their status, on antiretroviral therapy (ART), and virally suppressed. In 2020, these targets were ... ...

    Abstract Background: In 2014, UNAIDS set a goal to end the AIDS epidemic by achieving targets for the percentage of people living with HIV who were aware of their status, on antiretroviral therapy (ART), and virally suppressed. In 2020, these targets were revised to 95% for each measure (known as 95-95-95), to be reached among people living with HIV by 2025. We used data from the Fifth Botswana AIDS Impact Survey (BAIS V) to measure progress towards these testing and treatment targets in Botswana.
    Methods: BAIS V used a two-stage cluster design to obtain a nationally representative sample of people aged 15-64 years in Botswana. During March-August, 2021, 14 763 consenting participants were interviewed and tested for HIV in their households by survey teams. HIV-positive specimens were tested for viral load, presence of antiretroviral drugs, and recency of infection using the HIV-1 limiting antigen avidity enzyme immunoassay. Estimates of HIV-positive status and use of ART were based on self-report and the analysis of blood specimens for antiretroviral drugs. Viral load suppression was defined as an HIV RNA concentration of less than 1000 copies per mL. HIV incidence was calculated using the recent infection testing algorithm. Data were weighted to account for the complex survey design.
    Findings: The national HIV prevalence in Botswana among people aged 15-64 years was 20·8% and the annual incidence of HIV infection was 0·2%. 95·1% (men 93·0%, women 96·4%) of people living with HIV aged 15-64 years were aware of their status, 98·0% (men 97·2%, women 98·4%) of those aware were on ART, and 97·9% (men 96·6%, women 98·6%) of those on ART had viral load suppression. Among young people (aged 15-24 years) living with HIV, 84·5% were aware of their status, 98·5% of those aware were on ART, and 91·6% of those on ART had viral load suppression. The prevalance of viral load suppression among all people living with HIV was 91·8%, and varied by district-ranging from 85·3% in Gaborone to 100·0% in Selibe Phikwe.
    Interpretation: BAIS V is the first population-based survey worldwide to report the achievement of the UNAIDS 95-95-95 goals, both overall and among women. Strategies to reach undiagnosed men and young people, including young women, are needed.
    Funding: US President's Emergency Plan for AIDS Relief.
    MeSH term(s) Male ; Humans ; Female ; Adolescent ; Acquired Immunodeficiency Syndrome/drug therapy ; Acquired Immunodeficiency Syndrome/epidemiology ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Botswana/epidemiology ; Anti-Retroviral Agents/therapeutic use ; Surveys and Questionnaires ; Viral Load ; Prevalence
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2024-03-08
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2352-3018
    ISSN (online) 2352-3018
    DOI 10.1016/S2352-3018(24)00003-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Identification of Leukocyte Surface P2X7 as a Biomarker Associated with Alzheimer's Disease.

    Li, Yihan / Huang, Xin / Fowler, Christopher / Lim, Yen Y / Laws, Simon M / Faux, Noel / Doecke, James D / Trounson, Brett / Pertile, Kelly / Rumble, Rebecca / Doré, Vincent / Villemagne, Victor L / Rowe, Christopher C / Wiley, James S / Maruff, Paul / Masters, Colin L / Gu, Ben J

    International journal of molecular sciences

    2022  Volume 23, Issue 14

    Abstract: Alzheimer's disease (AD) has shown altered immune responses in the periphery. We studied P2X7 (a proinflammatory receptor and a scavenger receptor) and two integrins, CD11b and CD11c, on the surface of circulating leukocytes and analysed their ... ...

    Abstract Alzheimer's disease (AD) has shown altered immune responses in the periphery. We studied P2X7 (a proinflammatory receptor and a scavenger receptor) and two integrins, CD11b and CD11c, on the surface of circulating leukocytes and analysed their associations with Aβ-PET, brain atrophy, neuropsychological assessments, and cerebrospinal fluid (CSF) biomarkers. Total 287 age-matched, sex-balanced participants were recruited in a discovery cohort and two validation cohorts through the AIBL study and studied using tri-colour flow cytometry. Our results demonstrated reduced expressions of P2X7, CD11b, and CD11c on leukocytes, particularly monocytes, in Aβ +ve cases compared with Aβ -ve controls. P2X7 and integrin downregulation was observed at pre-clinical stage of AD and stayed low throughout disease course. We further constructed a polygenic risk score (PRS) model based on 12
    MeSH term(s) Alzheimer Disease/pathology ; Amyloid beta-Peptides/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Humans ; Integrins ; Leukocytes/pathology ; Peptide Fragments/cerebrospinal fluid ; tau Proteins/cerebrospinal fluid
    Chemical Substances Amyloid beta-Peptides ; Biomarkers ; Integrins ; Peptide Fragments ; tau Proteins
    Language English
    Publishing date 2022-07-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23147867
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  8. Article ; Online: Coccidioidomycosis outbreak among inmate wildland firefighters: California, 2017.

    Laws, Rebecca L / Jain, Seema / Cooksey, Gail Sondermeyer / Mohle-Boetani, Janet / McNary, Jennifer / Wilken, Jason / Harrison, Robert / Leistikow, Bruce / Vugia, Duc J / Windham, Gayle C / Materna, Barbara L

    American journal of industrial medicine

    2021  Volume 64, Issue 4, Page(s) 266–273

    Abstract: Background: In California, state prison inmates are employed to fight wildfires, which involves performing soil-disrupting work. Wildfires have become more common, including areas where Coccidioides, the soil-dwelling fungus that causes ... ...

    Abstract Background: In California, state prison inmates are employed to fight wildfires, which involves performing soil-disrupting work. Wildfires have become more common, including areas where Coccidioides, the soil-dwelling fungus that causes coccidioidomycosis, proliferates. However, work practices that place wildland firefighters at risk for coccidioidomycosis have not been investigated.
    Methods: On August 17, 2017, the California Department of Public Health was notified of a cluster of coccidioidomycosis cases among Wildfire A inmate wildland firefighters. We collected data through medical record abstraction from suspected case-patients and mailed a survey assessing potential job task risk factors to Wildfire A inmate firefighters. We described respondent characteristics and conducted a retrospective case-control investigation to assess coccidioidomycosis risk factors.
    Results: Among 198 inmate firefighters who worked on Wildfire A, 112 (57%) completed the survey. Of 10 case-patients (four clinical and six laboratory-confirmed), two were hospitalized. In the case-control analysis of 71 inmate firefighters, frequently cutting fire lines with a McLeod tool (odds ratio [OR]: 5.5; 95% confidence interval [CI]: 1.1-37.2) and being in a dust cloud or storm (OR: 4.3; 95% CI: 1.1-17.4) were associated with illness. Two of 112 inmate firefighters reported receiving coccidioidomycosis training; none reported wearing respiratory protection on this wildfire.
    Conclusions: Wildland firefighters who use hand tools and work in dusty conditions where Coccidioides proliferates are at risk for coccidioidomycosis. Agencies that employ them should provide training about coccidioidomycosis and risk reduction, limit dust exposure, and implement respiratory protection programs that specify where respirator use is feasible and appropriate.
    MeSH term(s) Adult ; California/epidemiology ; Case-Control Studies ; Coccidioides ; Coccidioidomycosis/epidemiology ; Coccidioidomycosis/microbiology ; Disease Outbreaks ; Firefighters/statistics & numerical data ; Humans ; Male ; Occupational Diseases/epidemiology ; Occupational Diseases/microbiology ; Occupational Exposure/adverse effects ; Prisoners/statistics & numerical data ; Wildfires
    Language English
    Publishing date 2021-01-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 604538-8
    ISSN 1097-0274 ; 0271-3586
    ISSN (online) 1097-0274
    ISSN 0271-3586
    DOI 10.1002/ajim.23218
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  9. Article ; Online: Dupilumab pharmacokinetics and effect on type 2 biomarkers in children with moderate-to-severe asthma.

    Jackson, Daniel J / Bacharier, Leonard B / Phipatanakul, Wanda / Sher, Lawrence / Domingo, Christian / Papadopoulos, Nikolaos / Modena, Brian / Li, Ning / Xia, Changming / Kamal, Mohamed A / Dillon, Myles / Wolfe, Kelley / Gall, Rebecca / Amin, Nikhil / Mannent, Leda P / Laws, Elizabeth / Rowe, Paul J / Jacob-Nara, Juby A / Deniz, Yamo /
    Lederer, David J / Hardin, Megan / Xu, Christine

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2023  Volume 131, Issue 1, Page(s) 44–51.e4

    Abstract: ... concentrations of 51.2 mg/L and 79.4 mg/L in children receiving dupilumab 100 mg every 2 weeks and 200 mg every 2 ... weeks, respectively (therapeutic range in adults and adolescents: 29-80 mg/L). Reductions in type 2 ...

    Abstract Background: Type 2 inflammation is common in children with asthma. Dupilumab, a human antibody, blocks the signaling of interleukin -4 and -13, key and central drivers of type 2 inflammation. In the LIBERTY ASTHMA VOYAGE (NCT02948959) study, dupilumab reduced severe asthma exacerbations and improved lung function in children aged 6 to 11 years with uncontrolled, moderate-to-severe asthma.
    Objective: To assess the pharmacokinetics of dupilumab and type 2 biomarker changes in children with type 2 asthma in VOYAGE.
    Methods: Patients were randomized to dupilumab 100 mg (≤30 kg) or 200 mg (>30 kg) or placebo every 2 weeks for 52 weeks. Dupilumab concentrations and changes in type 2 biomarkers were assessed at each visit.
    Results: Dupilumab concentrations in serum reached a steady state by week 12, with mean concentrations of 51.2 mg/L and 79.4 mg/L in children receiving dupilumab 100 mg every 2 weeks and 200 mg every 2 weeks, respectively (therapeutic range in adults and adolescents: 29-80 mg/L). Reductions in type 2 biomarkers were comparable between regimens, and greater in patients treated with dupilumab vs placebo. In children treated with dupilumab 100 mg and 200 mg every 2 weeks, the median percent changes (Q1-Q3) from baseline at week 52 were, respectively, -78.6% (-86.3 to -69.80) and -78.6% (-84.9 to -70.1) for serum total immunoglobulin E, -53.6% (-66.4 to -34.6) and -43.7% (-58.6 to -28.5) for thymus and activation-regulated chemokine; -25.7% (-60.0 to 27.6) and -33.3% (-60.6 to 16.6) for blood eosinophils, and -47.7% (-73.8 to 18.9) and -55.6% (-73.6 to -20.0) for fractional exhaled nitric oxide.
    Conclusion: Weight-tiered dose regimens achieved mean concentrations within the dupilumab therapeutic range. The median decreases in type 2 biomarker levels were similar between dose regimens.
    Trial registration: ClinicalTrials.gov Identifier: NCT02948959.
    MeSH term(s) Adult ; Adolescent ; Humans ; Child ; Antibodies, Monoclonal/therapeutic use ; Double-Blind Method ; Asthma/drug therapy ; Asthma/chemically induced ; Inflammation/drug therapy ; Biomarkers ; Treatment Outcome
    Chemical Substances dupilumab (420K487FSG) ; Antibodies, Monoclonal ; Biomarkers
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2023.03.014
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  10. Article ; Online: Occupational exposures and mitigation strategies among homeless shelter workers at risk of COVID-19.

    Rao, Carol Y / Robinson, Tashina / Huster, Karin / Laws, Rebecca L / Keating, Ryan / Tobolowsky, Farrell A / McMichael, Temet M / Gonzales, Elysia / Mosites, Emily

    PloS one

    2021  Volume 16, Issue 11, Page(s) e0253108

    Abstract: Objective: To describe the work environment and COVID-19 mitigation measures for homeless shelter workers and assess occupational risk factors for COVID-19.: Methods: Between June 9-August 10, 2020, we conducted a self-administered survey among ... ...

    Abstract Objective: To describe the work environment and COVID-19 mitigation measures for homeless shelter workers and assess occupational risk factors for COVID-19.
    Methods: Between June 9-August 10, 2020, we conducted a self-administered survey among homeless shelter workers in Washington, Massachusetts, Utah, Maryland, and Georgia. We calculated frequencies for work environment, personal protective equipment use, and SARS-CoV-2 testing history. We used generalized linear models to produce unadjusted prevalence ratios (PR) to assess risk factors for SARS-CoV-2 infection.
    Results: Of the 106 respondents, 43.4% reported frequent close contact with clients; 75% were worried about work-related SARS-CoV-2 infections; 15% reported testing positive. Close contact with clients was associated with testing positive for SARS-CoV-2 (PR 3.97, 95%CI 1.06, 14.93).
    Conclusions: Homeless shelter workers may be at risk of being exposed to individuals with COVID-19 during the course of their work. Frequent close contact with clients was associated with SARS-CoV-2 infection. Protecting these critical essential workers by implementing mitigation measures and prioritizing for COVID-19 vaccination is imperative during the pandemic.
    MeSH term(s) Adult ; Aged ; COVID-19/epidemiology ; COVID-19 Vaccines/therapeutic use ; Cell Movement/physiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Occupational Exposure/adverse effects ; Risk Factors ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Young Adult
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0253108
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