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  1. Article: Correction: Predictors of pulmonary embolism in hospitalized patients with COVID-19.

    Bahk, Jeeyune / Rehman, Abdul / Ho, Kam Sing / Narasimhan, Bharat / Baloch, Hafiza Noor Ul Ain / Zhang, Jiafang / Yip, Rowena / Lookstein, Robert / Steiger, David J

    Thrombosis journal

    2023  Volume 21, Issue 1, Page(s) 89

    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2118392-2
    ISSN 1477-9560
    ISSN 1477-9560
    DOI 10.1186/s12959-023-00531-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Syndrome of inappropriate antidiuretic hormone as the initial presentation of COVID-19: A novel case report.

    Ho, Kam Sing / Narasimhan, Bharat / Kumar, Aravinth / Flynn, Erin / Salonia, James / El-Hachem, Karim / Mathew, Joseph P

    Nefrologia

    2022  Volume 41, Issue 2, Page(s) 218–220

    Language English
    Publishing date 2022-09-27
    Publishing country Spain
    Document type Letter
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefroe.2021.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Commentary on Eosinophilic Inflammation, Coronavirus Disease 2019, and Asthma: Are inhaled corticosteroids the missing link?

    Ho, Kam Sing / Howell, Daniel / Rogers, Linda / Narasimhan, Bharat / Verma, Hannah / Steiger, David

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2021  Volume 127, Issue 2, Page(s) 279

    MeSH term(s) Adrenal Cortex Hormones/adverse effects ; Asthma/drug therapy ; COVID-19 ; Humans ; Inflammation ; SARS-CoV-2
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2021-05-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2021.04.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Genomic characteristics and viral load dynamics of a SARS-CoV-2 Omicron BA.2.2 variant from a hospitalized patient treated with molnupiravir.

    Chan, Wai Sing / Law, Janet Hei Yin / Ho, Matthew Kam Shing / Chan, Tsun Leung / Ma, Edmond Shiu Kwan / Tang, Bone Siu Fai

    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

    2022  Volume 105, Page(s) 105376

    Abstract: We sequenced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from nasal and throat swabs of a hospitalized patient during the fifth wave of coronavirus disease 2019 (COVID-19) pandemic in Hong Kong. Genomic characteristics and viral ... ...

    Abstract We sequenced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from nasal and throat swabs of a hospitalized patient during the fifth wave of coronavirus disease 2019 (COVID-19) pandemic in Hong Kong. Genomic characteristics and viral load dynamics of an Omicron BA.2.2 variant before and after molnupiravir treatment were presented.
    MeSH term(s) Humans ; SARS-CoV-2/genetics ; Viral Load ; COVID-19 ; Genomics
    Chemical Substances molnupiravir (YA84KI1VEW)
    Language English
    Publishing date 2022-10-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2037068-4
    ISSN 1567-7257 ; 1567-1348
    ISSN (online) 1567-7257
    ISSN 1567-1348
    DOI 10.1016/j.meegid.2022.105376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Asthma and COVID-19: lessons learned and questions that remain.

    Howell, Daniel / Verma, Hannah / Ho, Kam Sing / Narasimhan, Bharat / Steiger, David / Rogers, Linda

    Expert review of respiratory medicine

    2021  Volume 15, Issue 11, Page(s) 1377–1386

    Abstract: Introduction: Asthma is one of the most common chronic diseases worldwide. As a disease of the respiratory tract, the site of entry for the SARS-CoV-2 virus, there may be an important interplay between asthma and COVID-19 disease.: Areas covered: We ... ...

    Abstract Introduction: Asthma is one of the most common chronic diseases worldwide. As a disease of the respiratory tract, the site of entry for the SARS-CoV-2 virus, there may be an important interplay between asthma and COVID-19 disease.
    Areas covered: We report asthma prevalence among hospitalized cohorts with COVID-19. Those with non-allergic and severe asthma may be at increased risk of a worsened clinical outcome from COVID-19 infection. We explore the epidemiology of asthma as a risk factor for the severity of COVID-19 infection. We then consider the role COVID-19 may play in leading to exacerbations of asthma. The impact of asthma endotype on outcome is discussed. Lastly, we address the safety of common asthma therapeutics. A literature search was performed with relevant terms for each of the sections of the review using PubMed, Google Scholar, and Medline.
    Expert opinion: Asthma diagnosis may be a risk factor for severe COVID-19 especially for those with severe disease or nonallergic phenotypes. COVID-19 does not appear to provoke asthma exacerbations and asthma therapeutics should be continued for patients with exposure to COVID-19. Clearly much regarding this topic remains unknown and we identify some key questions that may be of interest for future researchers.[Figure: see text].
    MeSH term(s) Asthma/diagnosis ; Asthma/epidemiology ; COVID-19 ; Humans ; Prevalence ; Risk Factors ; SARS-CoV-2
    Language English
    Publishing date 2021-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2479146-5
    ISSN 1747-6356 ; 1747-6348
    ISSN (online) 1747-6356
    ISSN 1747-6348
    DOI 10.1080/17476348.2021.1985763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: MRI lesions in SpA: a comparison with noninflammatory back pain using propensity score adjustment method.

    Chung, Ho Yin / Huang, Jin Xian / Lee, Kam Ho / Tsang, Helen Hoi Lun / Lau, Chak Sing / Chan, Shirley Chiu Wai

    Therapeutic advances in musculoskeletal disease

    2022  Volume 14, Page(s) 1759720X221119250

    Abstract: Background: Magnetic resonance imaging (MRI) is important in the management of axial spondyloarthritis (SpA). However, many MRI lesions are not exclusive to axial SpA. Further characterization of these lesions may lead to better clinical decisions.: ... ...

    Abstract Background: Magnetic resonance imaging (MRI) is important in the management of axial spondyloarthritis (SpA). However, many MRI lesions are not exclusive to axial SpA. Further characterization of these lesions may lead to better clinical decisions.
    Objective: The objective of this study was to compare the frequency of individual spinal MRI lesions between axial SpA and noninflammatory back pain. The factors associated with individual lesions in participants with axial SpA were also determined.
    Design: This was a cross-sectional observational study.
    Methods: MRI lesions in 447 participants with axial SpA and 122 participants with noninflammatory back pain were compared using the propensity score adjustment method. Individual lesions included discovertebral lesions (DVL), Modic type 1 lesions, DVL without Modic type 1 lesions, facet joint lesions, costovertebral joint lesions, corner inflammatory lesions (CIL), and fatty corner lesions (FCL). The factors associated with the lesions were determined using regression analyses.
    Results: Among participants with axial SpA, 81.9% were HLA-B27-positive, 55.0% had radiographic axial SpA, and 60.5% had radiographic features of spinal damage (mSASSS >2). Almost half (48.6% in axial SpA
    Conclusion: MRI lesions including DVL without Modic type 1, costovertebral joint lesions, CIL, and FCL were more specific in axial SpA.
    Language English
    Publishing date 2022-08-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2516075-8
    ISSN 1759-7218 ; 1759-720X
    ISSN (online) 1759-7218
    ISSN 1759-720X
    DOI 10.1177/1759720X221119250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The relationship between asthma, eosinophilia, and outcomes in coronavirus disease 2019 infection.

    Ho, Kam Sing / Howell, Daniel / Rogers, Linda / Narasimhan, Bharat / Verma, Hannah / Steiger, David

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2021  Volume 127, Issue 1, Page(s) 42–48

    Abstract: Background: The impact of asthma diagnosis and asthma endotype on outcomes from coronavirus disease 2019 (COVID-19) infection remains unclear.: Objective: To describe the association between asthma diagnosis and endotype and clinical outcomes among ... ...

    Abstract Background: The impact of asthma diagnosis and asthma endotype on outcomes from coronavirus disease 2019 (COVID-19) infection remains unclear.
    Objective: To describe the association between asthma diagnosis and endotype and clinical outcomes among patients diagnosed as having COVID-19 infection.
    Methods: Retrospective multicenter cohort study of outpatients and inpatients presenting to 6 hospitals in the Mount Sinai Health System New York metropolitan region between March 7, 2020, and June 7, 2020, with COVID-19 infection, with and without a history of asthma. The primary outcome evaluated was in-hospital mortality. Secondary outcomes included hospitalization, intensive care unit admission, mechanical ventilation, and hospital length of stay. The outcomes were compared in patients with or without asthma using a multivariate Cox regression model. The outcomes stratified by blood eosinophilia count were also evaluated.
    Results: Of 10,523 patients diagnosed as having COVID-19 infection, 4902 were hospitalized and 468 had a diagnosis of asthma (4.4%). When adjusted for COVID-19 disease severity, comorbidities, and concurrent therapies, patients with asthma had a lower mortality (adjusted odds ratio [OR], 0.64 (0.53-0.77); P < .001) and a lower rate of hospitalization and intensive care unit admission (OR, 0.43 (0.28-0.64); P < .001 and OR, 0.51 (0.41-0.64); P < .001, respectively). Those with blood eosinophils greater than or equal to 200 cells/μL, both with and without asthma, had lower mortality.
    Conclusion: Patients with asthma may be at a reduced risk of poor outcomes from COVID-19 infection. Eosinophilia, both in those with and without asthma, may be associated with reduced mortality risk.
    MeSH term(s) Adult ; Aged ; Asthma/epidemiology ; Asthma/mortality ; COVID-19/epidemiology ; COVID-19/mortality ; COVID-19/therapy ; Comorbidity ; Eosinophilia/epidemiology ; Eosinophilia/mortality ; Female ; Hospital Mortality ; Hospitalization/statistics & numerical data ; Humans ; Intensive Care Units/statistics & numerical data ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Multivariate Analysis ; New York/epidemiology ; Proportional Hazards Models ; Respiration, Artificial/statistics & numerical data ; Retrospective Studies ; Severity of Illness Index
    Language English
    Publishing date 2021-02-27
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2021.02.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: TOCILIZUMAB USE IN SEVERE COVID-19

    Poon, Joseph / Ho, Kam Sing / Herrera, Yasmin / Jean, Raymonde

    Chest

    A SINGLE CENTER EXPERIENCE

    2020  Volume 158, Issue 4, Page(s) A687

    Keywords Critical Care and Intensive Care Medicine ; Pulmonary and Respiratory Medicine ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.08.646
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: CLINICAL OUTCOMES IN DIABETIC VS NON-DIABETIC PATIENTS WITH SEVERE COVID-19

    Poon, Joseph / Ho, Kam Sing / Herrera, Yasmin / Jean, Raymonde

    Chest

    2020  Volume 158, Issue 4, Page(s) A688

    Keywords Critical Care and Intensive Care Medicine ; Pulmonary and Respiratory Medicine ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.08.647
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Controversy over smoking in COVID-19-A real world experience in New York city.

    Ho, Kam Sing / Narasimhan, Bharat / Sheehan, Jacqueline / Wu, LingLing / Fung, Jennifer Y

    Journal of medical virology

    2021  Volume 93, Issue 7, Page(s) 4537–4543

    Abstract: Data are conflicting regarding the impact of tobacco smoking in people with pneumonia due to SARS-CoV-2 infection (COVID-19). We performed a retrospective multicentre cohort study of 9991 consecutive patients hospitalized in a major New York academic ... ...

    Abstract Data are conflicting regarding the impact of tobacco smoking in people with pneumonia due to SARS-CoV-2 infection (COVID-19). We performed a retrospective multicentre cohort study of 9991 consecutive patients hospitalized in a major New York academic center between March 7th and June 5th, 2020 with laboratory-confirmed COVID-19. The clinical outcomes assessed included risk of hospitalization, in-hospital mortality, risk of intensive care unit (ICU) admission, and need for mechanical ventilation among smokers (current and former). Multivariable logistic regression and propensity score models were built to adjust for potential confounders. Among 9991 consecutive patients diagnosed with COVID-19, 2212 (22.1%) patients were self-reported smokers (406 current and 1806 former). Current smoking was not associated with an increased risk of hospitalization (propensity score [PS]-adjusted OR 0.91; p = .46), in-hospital mortality (PS-OR 0.77; p = .12), ICU admission (PS-OR 1.18; p = .37), or intubation (PS-OR 1.04; p = .85). Similarly, former smoking was not associated with an increased risk of hospitalization (PS-OR 0.88; p = .11), in-hospital mortality (PS-OR 1.03; p = .78), ICU admission (PS-OR 1.03; p = .95), or intubation (PS-OR 0.93; p = .57). Furthermore, smoking (current or former) was not associated with an increased risk of hospitalization (PS-OR 0.85; p = .05), in-hospital mortality (PS-OR 0.94; p = .49), ICU admission (PS-OR 0.86; p = .17), or intubation (PS-OR 0.79; p = .06). Smoking is a well-known risk factor associated with greater susceptibility and subsequent increased severity of respiratory infections. In the current COVID-19 pandemic, smokers may have increased risk and severe pneumonia. In the current COVID-19 pandemic, smokers are believed to have an increased risk of mortality as well as severe pneumonia. However, in our analysis of real-world clinical data, smoking was not associated with increased in-patient mortality in COVID-19 pneumonia, in accordance with prior reports.
    MeSH term(s) COVID-19/mortality ; COVID-19/pathology ; Critical Care/statistics & numerical data ; Cytokine Release Syndrome/pathology ; Female ; Hospital Mortality ; Hospitalization/statistics & numerical data ; Humans ; Inflammation/pathology ; Male ; Middle Aged ; New York City ; Respiration, Artificial/statistics & numerical data ; Retrospective Studies ; SARS-CoV-2 ; Smoking/mortality
    Language English
    Publishing date 2021-03-25
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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