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Article ; Online: Tensor Sparse Representation for 3-D Medical Image Fusion Using Weighted Average Rule.

Haitao Yin

IEEE transactions on bio-medical engineering

2018 Volume 65, Issue 11, Page(s) 2622–2633

Abstract: Objective: The technique of fusing multimodal medical images into single image has a great impact on the clinical diagnosis. The previous works mostly concern the two-dimensional (2-D) image fusion performed on each slice individually, that may destroy ... ...

Abstract	Objective: The technique of fusing multimodal medical images into single image has a great impact on the clinical diagnosis. The previous works mostly concern the two-dimensional (2-D) image fusion performed on each slice individually, that may destroy the 3-D correlation across adjacent slices. To address this issue, this paper proposes a novel 3-D image fusion scheme based on Tensor Sparse Representation (TSR). Methods: First, each medical volume is arranged as a three-order tensor, and represented by TSR with learned dictionaries. Second, a novel "weighted average" rule, calculated from the tensor sparse coefficients using 3-D local-to-global strategy. The weights are then employed to combine the multimodal medical volumes through weighted average. Results: The visual and objective comparisons show that the proposed method is competitive to the existing methods on various medical volumes in different imaging modalities. Conclusion: The TSR-based 3-D fusion approach with weighted average rule can preserve the 3-D structure of medical volume, and reduce the low contrast and artifacts in fused product. Significance: The designed weights offer the effective assigned weights and accurate salience levels measure, which can improve the performance of fusion approach.
MeSH term(s)	Algorithms ; Brain/diagnostic imaging ; Humans ; Imaging, Three-Dimensional/methods ; Magnetic Resonance Imaging ; Multimodal Imaging/methods ; Positron-Emission Tomography
Language	English
Publishing date	2018-02-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	160429-6
ISSN	1558-2531 ; 0018-9294
ISSN (online)	1558-2531
ISSN	0018-9294
DOI	10.1109/TBME.2018.2811243
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Article ; Online: Melatonin ameliorates acute lung injury caused by paraquat poisoning by promoting PINK1 and BNIP3 expression.

Yin, Yiyuan / Shen, Haitao

Toxicology

2023 Volume 490, Page(s) 153506

Abstract: Paraquat (PQ) poisoning can result in multiple organ dysfunction syndrome, mainly manifesting as acute lung injury and acute respiratory distress syndrome. No specific cure exists for PQ poisoning. However, by scavenging mitochondrial DNA (mtDNA), the ... ...

Abstract	Paraquat (PQ) poisoning can result in multiple organ dysfunction syndrome, mainly manifesting as acute lung injury and acute respiratory distress syndrome. No specific cure exists for PQ poisoning. However, by scavenging mitochondrial DNA (mtDNA), the damage-associated molecular pattern during PQ poisoning, mitophagy can ameliorate the downstream inflammatory pathways activated by mtDNA. Melatonin (MEL), however, can promote the expression of PINK1 and BNIP3, which are key proteins involved in mitophagy. In this study, we first explored whether MT could reduce PQ-induced acute lung injury by affecting mitophagy in animal models, and then, we studied the specific mechanism associated with this process through in vitro experiments. We also evaluated MEL intervention in the PQ group, while inhibiting the expression of PINK1 and BNIP3, to further determine whether the protective effects of MEL are associated with its effect on mitophagy. We found that when the expression of PINK1 and BNIP3 was inhibited, MEL intervention could not reduce mtDNA leakage and the release of inflammatory factors caused by PQ exposure, suggesting that the protective effect of MEL was blocked. These results suggest that by promoting the expression of PINK1 and BNIP3 and activating mitophagy, MEL can reduce mtDNA/TLR9-mediated acute lung injury during PQ poisoning. The results of this study could provide guidance for the clinical treatment of PQ poisoning to reduce associated mortality.
MeSH term(s)	Animals ; Melatonin/pharmacology ; Paraquat/toxicity ; Acute Lung Injury/chemically induced ; Acute Lung Injury/drug therapy ; Acute Lung Injury/genetics ; DNA, Mitochondrial/genetics ; DNA, Mitochondrial/metabolism ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Lung
Chemical Substances	Melatonin (JL5DK93RCL) ; Paraquat (PLG39H7695) ; DNA, Mitochondrial ; Protein Kinases (EC 2.7.-)
Language	English
Publishing date	2023-04-05
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	184557-3
ISSN	1879-3185 ; 0300-483X
ISSN (online)	1879-3185
ISSN	0300-483X
DOI	10.1016/j.tox.2023.153506
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Article ; Online: Effect of point defects on the band alignment and transport properties of 1T-MoS

Cong, Yifei / Tao, Bairui / Lu, Xinzhu / Liu, Xiaojie / Wang, Yin / Yin, Haitao

Physical chemistry chemical physics : PCCP

2024 Volume 26, Issue 17, Page(s) 13230–13238

Abstract: Defects, which are an unavoidable component of the material preparation process, can have a significant impact on the properties of two-dimensional devices. In this work, we investigated theoretically the effects of different types and positions of point ...

Abstract	Defects, which are an unavoidable component of the material preparation process, can have a significant impact on the properties of two-dimensional devices. In this work, we investigated theoretically the effects of different types and positions of point defects on band alignment and transport properties of metallic 1T-phase MoS
Language	English
Publishing date	2024-05-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d4cp00707g
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Article ; Online: Pure spin current in a cobalt phthalocyanine chain induced by the photogalvanic effect.

Liu, Xiaojie / Tao, Bairui / Wang, Yin / Yin, Haitao

Physical chemistry chemical physics : PCCP

2023 Volume 25, Issue 30, Page(s) 20331–20336

Abstract: The development of methods for generating pure spin current at the molecular level is vital. In this work, we investigated how the spin-related photocurrent is produced in a cobalt phthalocyanine chain by the photogalvanic effect (PGE). Depending on how ... ...

Abstract	The development of methods for generating pure spin current at the molecular level is vital. In this work, we investigated how the spin-related photocurrent is produced in a cobalt phthalocyanine chain by the photogalvanic effect (PGE). Depending on how the magnetic moments of the left and right halves of the cobalt phthalocyanine chain are arranged, spin current can be generated. Both charge current and spin current are absent when the magnetic moments are arranged in parallel. Pure spin currents are generated when the magnetic moments are arranged in an antiparallel manner. Importantly, the pure spin current is robust to the polarization type and polarization angle. This characteristic results from the structure's charge density having spatial inversion symmetry but lacking that of the spin density.
Language	English
Publishing date	2023-08-02
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d3cp01530k
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Article ; Online: Willingness to Pay for Green Office: Evidence from Shanghai.

Zhang, Yanan / Yin, Haitao

Environmental science and pollution research international

2022 Volume 29, Issue 56, Page(s) 84345–84356

Abstract: The construction sector is a critical contributor to energy consumption and greenhouse gas emission. Promotion of green buildings may be a good way to tackle environmental problems. In this study, a choice experiment was undertaken to explore preferences ...

Abstract	The construction sector is a critical contributor to energy consumption and greenhouse gas emission. Promotion of green buildings may be a good way to tackle environmental problems. In this study, a choice experiment was undertaken to explore preferences and willingness to pay (WTP) for various attributes of green office buildings in Shanghai, with a sample of 309 respondents. Results of the mixed logit reveal that respondents value attributes relating to indoor comfortability and health, including Quiet Office Environment, Eco-Friendly Construction and Decoration Material, and Indoor Air Purification. Higher WTP is also observed for features of Power Saving and Water Saving, which provide both private and public benefits. According to heterogeneity analysis, people working in offices with a higher rent are more likely to pay for air purifier installation. In general, construction & manufacturing firms have higher WTP for Power Saving while lower WTP for Soundproof. On average, foreign firms are willing to pay more for eco-friendly materials. Finally, implications and suggestions for policymakers and building developers are discussed.
MeSH term(s)	Humans ; China ; Greenhouse Gases ; Surveys and Questionnaires
Chemical Substances	Greenhouse Gases
Language	English
Publishing date	2022-07-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-21555-6
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Article ; Online: Common methods in mitochondrial research (Review).

Yin, Yiyuan / Shen, Haitao

International journal of molecular medicine

2022 Volume 50, Issue 4

Abstract: Mitochondrial abnormalities are primarily seen in morphology, structure and function. They can cause damage to organs, including the heart, brain and muscle, by various mechanisms, such as oxidative stress, abnormal energy metabolism, or genetic ... ...

Abstract	Mitochondrial abnormalities are primarily seen in morphology, structure and function. They can cause damage to organs, including the heart, brain and muscle, by various mechanisms, such as oxidative stress, abnormal energy metabolism, or genetic mutations. Identifying and detecting pathophysiological alterations in mitochondria is the principal means of studying mitochondrial abnormalities. The present study reviewed methods in mitochondrial research and focused on three aspects: Mitochondrial extraction and purification, morphology and structure and function. In addition to classical methods, such as electron microscopy and mitochondrial membrane potential monitoring, newly developed methods, such as mitochondrial ultrastructural determination, mtDNA mutation assays, metabolomics and analyses of regulatory mechanisms, have also been utilized in recent years. These approaches enable the accurate detection of mitochondrial abnormalities and provide guidance for the diagnosis and treatment of related diseases.
MeSH term(s)	DNA, Mitochondrial/genetics ; DNA, Mitochondrial/metabolism ; Membrane Potential, Mitochondrial ; Mitochondria/metabolism ; Mutation ; Oxidative Stress
Chemical Substances	DNA, Mitochondrial
Language	English
Publishing date	2022-08-25
Publishing country	Greece
Document type	Journal Article
ZDB-ID	1444428-8
ISSN	1791-244X ; 1107-3756
ISSN (online)	1791-244X
ISSN	1107-3756
DOI	10.3892/ijmm.2022.5182
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Article: A China-Based Cost-Effectiveness Analysis of Novel Oral Anticoagulants versus Warfarin in Patients with Left Ventricular Thrombosis.

Tian, Shuo / Zhong, Haitao / Yin, Mengyue / Jiang, Pei / Liu, Qiao

Risk management and healthcare policy

2024 Volume 17, Page(s) 945–953

Abstract: Purpose: This study aims to conduct a comprehensive cost-effectiveness comparison between novel oral anticoagulants (NOACs) and warfarin in Chinese patients with left ventricular thrombosis (LVT). By incorporating the impact of volume-based procurement ( ...

Abstract	Purpose: This study aims to conduct a comprehensive cost-effectiveness comparison between novel oral anticoagulants (NOACs) and warfarin in Chinese patients with left ventricular thrombosis (LVT). By incorporating the impact of volume-based procurement (VBP) policy for pharmaceuticals in China, this analysis intends to provide crucial insights for informed healthcare decision-making. Patients and methods: A Markov model was employed to simulate the disease progression of LVT over a 54-week time horizon, using weekly cycles and six mutually exclusive health states. The model incorporated transition probabilities between health states calculated based on clinical trial data and literature sources. Various cost and utility parameters were also included. Additionally, a series of sensitivity analyses were conducted to address parameter variations and associated uncertainties. Results: The study finding suggest that from the perspective of Chinese healthcare, the majority of brand-name drug (BND) NOACs generally lack cost-effectiveness when compared to warfarin. However, when considered the VBP policy, NOACs, particularly rivaroxaban, prove to be more cost-effective than warfarin. Rivaroxaban provided an additional 0.0304 quality-adjusted life years (QALYs) per patient and reduced overall medical costs by 9095.73 CNY, resulting in an incremental cost-effectiveness ratio (ICER) of -298,786.20 CNY/QALY. Sensitivity analysis indicated a 78.4% probability of any NOACs being more cost-effective compared to warfarin. However, specifically considering NOACs under the VBP policy, the likelihood of them being more cost-effective approached 90%. Conclusion: Taking into account Chinese pharmaceutical procurement policies, the findings highlight the superior efficacy of NOACs, especially rivaroxaban, in enhancing both the quality of life and economic benefits for Chinese LVT patients. NOACs present a more cost-effective treatment option, improving patient quality of life and healthcare cost efficiency compared to warfarin.
Language	English
Publishing date	2024-04-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2495128-6
ISSN	1179-1594
ISSN	1179-1594
DOI	10.2147/RMHP.S454463
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Article: Near-natural transformation of

Yin, You / Li, Qiuli / Du, Haitao

PeerJ

2021 Volume 9, Page(s) e12098

Abstract: ... Pinus ... ...

Abstract	Pinus tabulaeformis
Language	English
Publishing date	2021-09-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2703241-3
ISSN	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.12098
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Article: Factors associated with sleep disorders among university students in Jiangsu Province: a cross-sectional study.

Hu, Bin / Wu, Qi / Wang, Yue / Zhou, Haitao / Yin, Dehui

Frontiers in psychiatry

2024 Volume 15, Page(s) 1288498

Abstract: Objective: This study aims to establish the precise prevalence of sleep disorders among university students in Jiangsu Province. Utilizing a representative sample of students, we measured their sleep quality based on the Pittsburgh Sleep Quality Index ( ... ...

Abstract	Objective: This study aims to establish the precise prevalence of sleep disorders among university students in Jiangsu Province. Utilizing a representative sample of students, we measured their sleep quality based on the Pittsburgh Sleep Quality Index (PSQI). Our objective is to quantitatively assess the magnitude of sleep quality and identify key factors. By detailed analysis of these relationships, our study seeks to provide actionable insights for the development of targeted interventions to enhance sleep quality within this population. Methods: From October to November 2022, we conducted a cross-sectional web-based survey in Jiangsu Province, China. Using convenient cluster sampling in each college, a total of 8457 participants were selected. The PSQI was applied to assess sleep quality among university students. Data collected included sociodemographic details, scores from the Mobile Phone Dependence Index (MPAI) and psychological resilience measured by the Connor-Davidson Resilience Scale (CD-RISC). Results: The overall prevalence of poor sleep quality among the participants was 39.30%. Binary logistic regression analysis revealed that higher physical activity (OR = 0.921; 95% CI: 0.779-1.090), earlier roommate bedtimes (OR = 0.799; 95% CI: 0.718-0.888), quieter dormitories (OR = 0.732; 95% CI: 0.647-0.828) and higher psychological resilience (OR = 0.982; 95% CI, 0.979-0.984) were protective factors linked to lower risk of poor sleep quality. Conversely, being a female student (OR = 1.238; 95% CI: 1.109-1.382), being a senior (OR = 1.582; 95% CI: 1.344-1.863), single-child status (OR = 1.195; 95% CI: 1.077-1.326), regular smoking (OR = 1.833; 95% CI: 1.181-2.847), regular alcohol consumption (OR = 1.737; 95% CI: 1.065-2.833), high academic stress (OR = 1.326; 95% CI: 1.012-1.736), high employment stress (OR = 1.352; 95% CI: 1.156-1.582), dissatisfaction with dormitory hygiene (OR = 1.140; 95% CI: 1.028-1.265), poor self-rated physical health (OR = 1.969; 95% CI: 1.533-2.529), poor self-rated mental health (OR = 2.924; 95% CI: 2.309-3.702) and higher mobile phone dependency were risk factors associated with an increased likelihood of poor sleep quality. Conclusion: The sleep quality among university students should attract immediate attention. The development of public services and mental health education initiatives is crucial in enhancing the sleep health of this population.
Language	English
Publishing date	2024-02-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2024.1288498
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Article ; Online: Effect of vacancy defects on transport in all-phosphorene nanoribbon devices from first principles.

Huang, Jingyuan / Zhang, Qiang / Liu, Xiaojie / Wang, Yin / Yin, Haitao

Physical chemistry chemical physics : PCCP

2023 Volume 25, Issue 27, Page(s) 18378–18386

Abstract: Defects in experimentally manufactured phosphorene nanoribbons (PNRs) occur unavoidably, affecting the functionality of PNR-based devices. In this work, we theoretically propose and investigate an all-PNR devices with single-vacancy (SV) defects and ... ...

Abstract	Defects in experimentally manufactured phosphorene nanoribbons (PNRs) occur unavoidably, affecting the functionality of PNR-based devices. In this work, we theoretically propose and investigate an all-PNR devices with single-vacancy (SV) defects and double-vacancy (DV) defects along the zigzag direction, accounting for both hydrogen passivation and non-passivation scenarios. We discovered that, in the case of hydrogen passivation, the DV defect can introduce in-gap states, whereas the SV defect can result in p-type doping. The unpassivated hydrogen nanoribbon exhibits an edge state with a considerable influence on the transport properties, which also masks the effect of defects on transport; furthermore, it demonstrates the phenomenon of negative differential resistance, whose occurrence and characteristics depend less on the presence or absence of defects.
Language	English
Publishing date	2023-07-12
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d3cp01266b
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