Article ; Online: Osilodrostat in Cushing's disease: The risk of delayed adrenal insufficiency should be carefully monitored.
2021 Volume 98, Issue 4, Page(s) 629–630
Abstract: Antisecretory data shows a highly effective and prolonged blockade of cortisol secretion with osilodrostat. The drawback is the occurrence of adrenal insufficiency (AI) in roughly a quarter of treated patients. In this short manuscript, we report three ... ...
Abstract | Antisecretory data shows a highly effective and prolonged blockade of cortisol secretion with osilodrostat. The drawback is the occurrence of adrenal insufficiency (AI) in roughly a quarter of treated patients. In this short manuscript, we report three cases of atypical adrenal insufficiency with osilodrostat. |
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MeSH term(s) | Humans ; Pituitary ACTH Hypersecretion/complications ; Hydrocortisone/therapeutic use ; Adrenal Insufficiency ; Imidazoles |
Chemical Substances | Osilodrostat (5YL4IQ1078) ; Hydrocortisone (WI4X0X7BPJ) ; Imidazoles |
Language | English |
Publishing date | 2021-07-22 |
Publishing country | England |
Document type | Letter |
ZDB-ID | 121745-8 |
ISSN | 1365-2265 ; 0300-0664 |
ISSN (online) | 1365-2265 |
ISSN | 0300-0664 |
DOI | 10.1111/cen.14551 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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