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  1. Article ; Online: In regard to "Dose escalation in the radiation therapy of prostate cancer" (Int J Radiat Oncol Biol Phys 2011;80:1289-1291).

    Bowes, David / Crook, Juanita

    International journal of radiation oncology, biology, physics

    2012  Volume 82, Issue 4, Page(s) 1317–1318

    MeSH term(s) Humans ; Male ; Prostatic Neoplasms/radiotherapy ; Radiotherapy Dosage
    Language English
    Publishing date 2012-03-15
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2011.11.010
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    Zs.A 1218: Show issues Location:
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  2. Article ; Online: Editorial Comment.

    Crook, Juanita

    The Journal of urology

    2024  , Page(s) 101097JU0000000000003987

    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003987
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  3. Article ; Online: The role of radiotherapy in the management of squamous cell cancer of the penis.

    Crook, Juanita

    World journal of urology

    2023  Volume 41, Issue 12, Page(s) 3913–3920

    Abstract: Purpose: To review the evidence for radiotherapy in the management of primary penile cancer, either as brachytherapy or external beam radiation, and the role of external beam radiotherapy in node positive penile cancer.: Methods: English language ... ...

    Abstract Purpose: To review the evidence for radiotherapy in the management of primary penile cancer, either as brachytherapy or external beam radiation, and the role of external beam radiotherapy in node positive penile cancer.
    Methods: English language literature was reviewed for the past 3 decades. As penile cancer is uncommon in developed nations, high quality evidence to guide management is limited. Single institution reports often span decades during which time staging systems and treatments have evolved, reducing their relevance to current practice. Successful clinical trials require collaboration not only among disciplines but also among multiple institutions and nations.
    Results: Radiotherapy is a definitive organ-preserving option for T1-T2 penile cancers. Interstitial brachytherapy is associated with penile preservation in 85% of men at 5 years, maintained in 70% by 10 years. Results of external radiotherapy are not quite as promising but nonetheless 60% of men will have an intact penis at 5 years. Inguino-pelvic external radiotherapy has been reported to increase overall survival when delivered as adjuvant treatment for men with pN3 groin but pN0 pelvic nodes, and improve disease specific survival for those with involved pelvic nodes. InPACT (ECOG-ACRIN_8134) is investigating the role of inguino-pelvic chemo-radiotherapy for men with pN3 inguinal nodes but imaging negative pelvic nodes.
    Conclusions: Radiotherapy has a well-defined role to play in treatment of squamous cell cancers of other sites, such as vulva, anal canal, uterine cervix and head and neck malignancies. Emerging data support the incorporation of radiotherapy into treatment paradigms for penile cancer.
    MeSH term(s) Humans ; Male ; Brachytherapy/methods ; Carcinoma, Squamous Cell/pathology ; Combined Modality Therapy ; Neoplasm Staging ; Penile Neoplasms/pathology ; Penis/pathology
    Language English
    Publishing date 2023-11-23
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-023-04683-7
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  4. Article ; Online: Perspective: Social License as a Lens for Improving Ethical and Welfare Standards in Cephalopod Research.

    Crook, Robyn J

    Integrative and comparative biology

    2023  Volume 63, Issue 6, Page(s) 1307–1315

    Abstract: Interest in cephalopods as comparative models in neuroscience, cognition, behavior, and ecology is surging due to recent advances in culture and experimental techniques. Although cephalopods have a long history in research, their use had remained limited ...

    Abstract Interest in cephalopods as comparative models in neuroscience, cognition, behavior, and ecology is surging due to recent advances in culture and experimental techniques. Although cephalopods have a long history in research, their use had remained limited due to the challenges of funding work on comparative models, the lack of modern techniques applicable to them, and the small number of labs with the facilities to keep and house large numbers of healthy animals for long periods. Breakthroughs in each of these areas are now creating new interest in cephalopods from researchers who trained and worked in other models, as well as allowing established cephalopod labs to grow and collaborate more widely. This broadening of the field is essential to its long-term health, but also brings with it new and heightened scrutiny from animal rights organizations, federal regulatory agencies, and members of the public. As a community, it is critical that scientists working with cephalopods engage in discussions, studies, and communication that promote high standards for cephalopod welfare. The concept of "social license to operate," more commonly encountered in industry, recreation, and agriculture, provides a useful lens through which to view proactive steps the cephalopod research community may take to ensure a strong future for our field. In this Perspective, I discuss recent progress in cephalopod ethics and welfare studies, and use the conceptual framework of Social License to Operate to propose a forward-looking, public-facing strategy for the parallel development of welfare-focused best practices and scientific breakthroughs.
    MeSH term(s) Animals ; Cephalopoda ; Cognition ; Agriculture ; Ecology
    Language English
    Publishing date 2023-07-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2159110-6
    ISSN 1557-7023 ; 1540-7063
    ISSN (online) 1557-7023
    ISSN 1540-7063
    DOI 10.1093/icb/icad099
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  5. Article: The wonder and magic of the natural world.

    Crook, Janice

    The Canadian veterinary journal = La revue veterinaire canadienne

    2022  Volume 63, Issue 4, Page(s) 345

    Language English
    Publishing date 2022-03-29
    Publishing country Canada
    Document type Letter ; Comment
    ZDB-ID 41603-4
    ISSN 0008-5286
    ISSN 0008-5286
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  6. Article ; Online: Long-term versus short-term androgen deprivation combined with EBRT for unfavourable prostate cancer.

    Crook, Juanita

    The Lancet. Oncology

    2022  Volume 23, Issue 5, Page(s) 558–560

    MeSH term(s) Androgen Antagonists/adverse effects ; Androgens ; Brachytherapy ; Combined Modality Therapy ; Humans ; Male ; Prostate-Specific Antigen ; Prostatic Neoplasms/drug therapy ; Retrospective Studies
    Chemical Substances Androgen Antagonists ; Androgens ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2022-04-12
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(22)00223-6
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    Zs.A 5696: Show issues Location:
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    Zs.MO 460: Show issues

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  7. Article ; Online: Behavioral and neurophysiological evidence suggests affective pain experience in octopus.

    Crook, Robyn J

    iScience

    2021  Volume 24, Issue 3, Page(s) 102229

    Abstract: Pain is a negative affective state arising from tissue damage or inflammation. Because pain is aversive and its relief is innately rewarding, animals may learn to avoid a context in which pain is experienced and prefer one where pain relief occurs. It is ...

    Abstract Pain is a negative affective state arising from tissue damage or inflammation. Because pain is aversive and its relief is innately rewarding, animals may learn to avoid a context in which pain is experienced and prefer one where pain relief occurs. It is generally accepted that vertebrate animals experience pain; however, there is currently inconclusive evidence that the affective component of pain occurs in any invertebrate. Here, we show that octopuses, the most neurologically complex invertebrates, exhibit cognitive and spontaneous behaviors indicative of affective pain experience. In conditioned place preference assays, octopuses avoided contexts in which pain was experienced, preferred a location in which they experienced relief from pain, and showed no conditioned preference in the absence of pain. Injection site grooming occurred in all animals receiving acetic acid injections, but this was abolished by local anesthesia. Thus, octopuses are likely to experience the affective component of pain.
    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2021.102229
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  8. Article ; Online: Organ preserving radiation strategies for penile cancer.

    Crook, Juanita

    Urologic oncology

    2020  Volume 40, Issue 5, Page(s) 184–190

    Abstract: Introduction: The majorities of penile cancers are of squamous cell origin and thus are amenable to treatment and cure by radiation. Despite the move toward penile sparing strategies, radiation remains an under-utilized and often neglected option. This ... ...

    Abstract Introduction: The majorities of penile cancers are of squamous cell origin and thus are amenable to treatment and cure by radiation. Despite the move toward penile sparing strategies, radiation remains an under-utilized and often neglected option. This paper will review the various radio-therapeutic approaches for penile cancer and the literature supporting their use. English, French and Spanish literature on penile cancer was reviewed for the past 5 decades and classified according to modality: external beam radiotherapy, interstitial brachytherapy and surface mold brachytherapy. Many series span several decades and include a wide range of stages, especially for external beam radiotherapy. Penile preservation obviously will depend on dose prescription and stage at treatment. Nonetheless, in general, penile sparing with external beam ranges from 36% to 66% at 5 years. For the selected patients appropriate for interstitial brachytherapy penile sparing is 77% to 87% at 5 years, decreasing to 70% at 10 years. Mold therapy is selected for those with very superficial disease and penile sparing is consequently higher.
    Conclusions: The development of centers of excellence for the management of this uncommon disease is encouraged. The required surgical and radiotherapy skill sets cannot be expected to be available in all centers. A multidisciplinary evaluation of each patient will facilitate selection of optimal management from the outset.
    MeSH term(s) Brachytherapy ; Humans ; Male ; Penile Neoplasms/radiotherapy ; Penile Neoplasms/surgery ; Penis
    Language English
    Publishing date 2020-07-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1336505-8
    ISSN 1873-2496 ; 1078-1439
    ISSN (online) 1873-2496
    ISSN 1078-1439
    DOI 10.1016/j.urolonc.2020.06.025
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    Zs.A 4817: Show issues Location:
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  9. Article ; Online: Adjuvant and Neoadjuvant Treatments for Resectable Hepatocellular Carcinoma.

    Crook, Christiana J / Li, Daneng

    Current oncology reports

    2023  Volume 25, Issue 10, Page(s) 1191–1201

    Abstract: Purpose of review: This review provides an update on the developments of adjuvant and neoadjuvant liver-directed and systemic therapy options for patients with resectable hepatocellular carcinoma.: Recent findings: Data on liver-directed treatment in ...

    Abstract Purpose of review: This review provides an update on the developments of adjuvant and neoadjuvant liver-directed and systemic therapy options for patients with resectable hepatocellular carcinoma.
    Recent findings: Data on liver-directed treatment in the adjuvant and neoadjuvant settings are sparse and results are conflicting; many studies suggest that optimizing patient selection criteria is a key milestone required to improve study design and clinical benefit to patients. Systemic treatment options are primarily focused on investigation of anti-PD-1/L1 immunotherapeutic agents, either alone or in combination with other drugs. Numerous clinical trials in both adjuvant and neoadjuvant settings are in progress. Exploration of liver-directed and systemic treatment options for adjuvant and neoadjuvant treatment of patients with resectable hepatocellular carcinoma has the potential to improve clinical outcomes for this patient population.
    Language English
    Publishing date 2023-09-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057359-5
    ISSN 1534-6269 ; 1523-3790
    ISSN (online) 1534-6269
    ISSN 1523-3790
    DOI 10.1007/s11912-023-01455-9
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  10. Article ; Online: Editorial Comment.

    Crook, Juanita

    The Journal of urology

    2019  Volume 201, Issue 6, Page(s) 1133

    MeSH term(s) Biopsy ; Humans ; Male ; Prostatic Neoplasms
    Language English
    Publishing date 2019-02-28
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/01.JU.0000554393.69622.3c
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