Article ; Online: REduced-Carbohydrate intervention for managing Obesity and Reduction of gestational Diabetes (RECORD): A randomized controlled feasibility trial.
Diabetes, obesity & metabolism
2024 Volume 26, Issue 4, Page(s) 1407–1420
Abstract: Aim: To test the feasibility and acceptability of a reduced-carbohydrate dietary program, intended to reduce the risk of gestational diabetes.: Materials and methods: Fifty-one pregnant women at <20 weeks' gestation, with body mass index ≥30 kg/m: ... ...
Abstract | Aim: To test the feasibility and acceptability of a reduced-carbohydrate dietary program, intended to reduce the risk of gestational diabetes. Materials and methods: Fifty-one pregnant women at <20 weeks' gestation, with body mass index ≥30 kg/m Results: Forty-nine of 51 participants attended the follow-up OGTT, a retention rate of 96% (95% confidence interval [CI] 86.8%-98.9%). In the intervention group, carbohydrate intake at follow-up was 190.4 (95% CI 162.5-215.6) g/day, a reduction of -24.6 (95% CI -51.5-2.4) g/day from baseline. Potentially favourable effects of the intervention on glucose control, weight gain and blood pressure were observed, but the study was not powered to detect significant differences in these. Participants found the intervention acceptable, and were content with the study processes, but some reported barriers to sustained adherence, mainly pertaining to competing priorities. Conclusions: Retention was high, suggesting the study processes are feasible, but the carbohydrate reduction in the intervention group was small, and did not meet progression criteria, limiting the likelihood of achieving the desired goal to prevent gestational diabetes. Trial registration number: ISRCTN16235884. |
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MeSH term(s) | Infant, Newborn ; Pregnancy ; Female ; Humans ; Diabetes, Gestational/prevention & control ; Feasibility Studies ; Obesity/complications ; Obesity/therapy ; Weight Gain ; Carbohydrates ; Diet, Carbohydrate-Restricted |
Chemical Substances | Carbohydrates |
Language | English |
Publishing date | 2024-01-16 |
Publishing country | England |
Document type | Randomized Controlled Trial ; Journal Article |
ZDB-ID | 1454944-x |
ISSN | 1463-1326 ; 1462-8902 |
ISSN (online) | 1463-1326 |
ISSN | 1462-8902 |
DOI | 10.1111/dom.15442 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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