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Article: [Besprechung von:] Wolfe, J. N. and M. Pickford: The Church of Scotland. An economic survey. London 1980

McHugh, Francis P / Pickford, M / Wolfe, J. N

The economic journal : the journal of the Royal Economic Society Vol. 91 , p. 582-583

1981 Volume 91, Page(s) 582–583

Author's details	Francis P. McHugh
Publisher	Blackwell
Publishing place	Oxford [u.a.]
Document type	Article
ZDB-ID	3025-9
Database	ECONomics Information System

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Article: ECG findings in professional rugby players using international screening recommendations.

McHugh, Clíodhna / Petek, Bradley / Grant, Aubrey J / Gustus, Sarah / van Dyk, Nicol / Hind, Karen / Wilson, Fiona / Wasfy, Meagan

BMJ open sport & exercise medicine

2024 Volume 10, Issue 1, Page(s) e001813

Abstract: ... professional rugby players' ECGs (n=356, male 79%) obtained during preparticipation screening (2010-2022 ... had borderline or abnormal ECG findings. Borderline findings were present in 3% (n=12/356) of players ... Abnormal findings were present in 2% (n=7/356) of players. Overall, 2.2% of ECGs were 'positive' (n=8/356 ...

Abstract	Background: While World Rugby guidelines do not mandate the inclusion of an electrocardiogram (ECG) for all players, this is required for entry into international rugby competitions. We, therefore, sought to describe sport-specific normative ECG values and evaluate the performance of contemporary athlete ECG guidelines in male and female professional rugby players. Methods: We retrospectively analysed professional rugby players' ECGs (n=356, male 79%) obtained during preparticipation screening (2010-2022), comparing by sex and playing position (forwards vs backs). ECGs were categorised as normal 'training-related', borderline and abnormal findings, as defined by the 2017 International Recommendations. Results: 84% of players had one or more normal, 'training-related' findings, with males having a higher prevalence than females (91% vs 60%, p<0.001). Most ECG findings did not vary by position. No female player had borderline or abnormal ECG findings. Borderline findings were present in 3% (n=12/356) of players. Abnormal findings were present in 2% (n=7/356) of players. Overall, 2.2% of ECGs were 'positive' (n=8/356, including n=1 ECG with two borderline findings). Conclusions: The application of contemporary ECG interpretation criteria resulted in a low positivity rate isolated to male players. These results help inform the logistic feasibility of ECG-inclusive screening, which is already required to enter major tournaments.
Language	English
Publishing date	2024-03-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2817580-3
ISSN	2055-7647
ISSN	2055-7647
DOI	10.1136/bmjsem-2023-001813
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of greenhouse gas emissions from sheep measured using both respiration and portable accumulation chambers.

O' Connor, E / McGovern, F M / Berry, D P / Dunne, E / McEwan, J C / Rowe, S J / Boland, T M / Morrison, S J / Aubry, A / Yan, T / McHugh, N

Animal : an international journal of animal bioscience

2024 Volume 18, Issue 5, Page(s) 101140

Abstract: ... Methane ( ... ...

Abstract	Methane (CH
Language	English
Publishing date	2024-03-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2257920-5
ISSN	1751-732X ; 1751-7311
ISSN (online)	1751-732X
ISSN	1751-7311
DOI	10.1016/j.animal.2024.101140
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Article ; Online: Camptodactyly and DiGeorge syndrome: A rare hand anomaly.

Hurley, C M / McHugh, N / Carr, S / Kelly, J L

JPRAS open

2021 Volume 28, Page(s) 126–130

Abstract: The most common deletion syndrome is 22q11.2 and it effects an estimated 1 in 3000 live births. Major features of this multisystem condition include congenital abnormalities, developmental delay, learning difficulties, immunodeficiency, endocrine ... ...

Abstract	The most common deletion syndrome is 22q11.2 and it effects an estimated 1 in 3000 live births. Major features of this multisystem condition include congenital abnormalities, developmental delay, learning difficulties, immunodeficiency, endocrine anomalies and an array of psychiatric disorders. However, variability in phenotype and severity may cause the diagnosis to be overlooked. Early clinical recognition and treatment of DiGeorge syndrome has been shown to increase early life survival, decrease complications and enhance overall quality of life. Skeletal anomalies are infrequently described in 22q11.2 but a subset of patients exhibit upper and lower limb deformities. We present the case of a 5 year-old girl with bilateral fifth digit camptodactyly caused by a fibrous band, and the surgical management of this condition. The current report adds to the body of evidence that camptodactyly is a rare clinical feature of 22q11.2 deletion syndrome, and may serve as a diagnostic aid in these patients.
Language	English
Publishing date	2021-03-19
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2834721-3
ISSN	2352-5878 ; 2352-5878
ISSN (online)	2352-5878
ISSN	2352-5878
DOI	10.1016/j.jpra.2021.03.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Mechanical symptoms and meniscal tear: a reappraisal.

McHugh, C G / Matzkin, E G / Katz, J N

Osteoarthritis and cartilage

2021 Volume 30, Issue 2, Page(s) 178–183

Abstract: Objective: To identify and summarize literature related to the association between mechanical symptoms (catching and locking of the knee), the presence of meniscal tear, and outcomes after arthroscopic surgery.: Design: We searched PubMed and hand- ... ...

Abstract	Objective: To identify and summarize literature related to the association between mechanical symptoms (catching and locking of the knee), the presence of meniscal tear, and outcomes after arthroscopic surgery. Design: We searched PubMed and hand-searched reference lists for relevant articles and selected 38 for analysis. Results: Mechanical symptoms appear to have modest sensitivity (ranging 0.32-0.69), specificity (ranging 0.45-0.74) and positive predictive value (ranging 0.75-0.81) for meniscal tear. There is also very little evidence to suggest that those with mechanical symptoms experience better outcomes after arthroscopic surgery. Conclusion: Our examination of the literature does not support the hypothesis that mechanical symptoms are related to the presence of meniscal tear or portend better outcomes after arthroscopic surgery.
MeSH term(s)	Arthroscopy ; Biomechanical Phenomena ; Humans ; Magnetic Resonance Imaging ; Symptom Assessment ; Tibial Meniscus Injuries/diagnosis ; Tibial Meniscus Injuries/physiopathology
Language	English
Publishing date	2021-09-29
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	1167809-4
ISSN	1522-9653 ; 1063-4584
ISSN (online)	1522-9653
ISSN	1063-4584
DOI	10.1016/j.joca.2021.09.009
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Article ; Online: Effectiveness of remote exercise programs in reducing pain for patients with knee osteoarthritis: A systematic review of randomized trials.

McHugh, C G / Kostic, A M / Katz, J N / Losina, E

Osteoarthritis and cartilage open

2022 Volume 4, Issue 3, Page(s) 100264

Abstract: Objective: Remote knee osteoarthritis (OA) management programs are becoming more popular. This systematic review examined the efficacy of remote exercise programs for relieving pain in persons with knee OA.: Design: We conducted a search of studies ... ...

Abstract	Objective: Remote knee osteoarthritis (OA) management programs are becoming more popular. This systematic review examined the efficacy of remote exercise programs for relieving pain in persons with knee OA. Design: We conducted a search of studies published between January 1st, 2013 to March 31st, 2021 in PubMed, Embase, and MEDLINE. We included randomized trials of patients with knee OA or chronic knee pain, studying interventions with an element of telehealth exercise management, and evaluating knee pain as an outcome. Interventions could include fully remote or both remote and in-person components. We excluded observational cohort studies, pilot studies, and studies with poor Physiotherapy Exercise Database (PEDro) scores. Two reviewers extracted pain data, consisting of mean differences from baseline and between groups, and compared them to minimum clinically important difference (MCID) thresholds. Results: We identified 1867 reports, of which eleven trials with a total of 1861 participants met inclusion criteria. Only one trial demonstrated a clinically meaningful change from baseline between groups. Four interventions were found to result in clinically meaningful improvements in pain from baseline. Conclusion: This review was limited by variability in outcome measures, intervention content, and comparators. One trial with an inactive control demonstrated clinically meaningful between group differences in pain. All four interventions demonstrating meaningful improvements from baseline included study-initiated communications to discuss and personalize remotely delivered exercise programs. More studies comparing fully or partially remote exercise programs with both active and inactive controls could help optimize the use of remote programs for management of knee OA pain.
Language	English
Publishing date	2022-05-14
Publishing country	England
Document type	Journal Article
ISSN	2665-9131
ISSN (online)	2665-9131
DOI	10.1016/j.ocarto.2022.100264
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Article ; Online: Incorporation of the grazing utilization subindex and new updates to the Pasture Profit Index.

Tubritt, T / Shalloo, L / Gilliland, T J / McHugh, N / O'Donovan, M

Journal of dairy science

2021 Volume 104, Issue 10, Page(s) 10841–10853

Abstract: Grazing efficiency has been shown to differ between perennial ryegrass varieties. Such differences affect the utilization of grass within grazing systems, influencing the profitability of grass-based ruminant production systems. The Pasture Profit Index ( ...

Abstract	Grazing efficiency has been shown to differ between perennial ryegrass varieties. Such differences affect the utilization of grass within grazing systems, influencing the profitability of grass-based ruminant production systems. The Pasture Profit Index (PPI) is an economic merit grass variety selection tool developed to identify varieties with the greatest economic potential for grass-based dairy production systems. A new grass utilization subindex was developed and incorporated into the PPI to identify varieties with superior grazing efficiency. The subindex rewards varieties with superior grazing efficiency, measured as Residual grazed height, as these varieties allow increased amounts of herbage dry matter to be used by grazing animals. The economic values of all other traits within the PPI were reviewed and updated to ensure that the index was reflective of the current economic scenarios with appropriate assumptions included in the models, thus ensuring that varieties excelling in the agronomic traits with the greatest effect on profitability were recognized. The difference between the highest and lowest performing varieties for the grass utilization trait ranged from €23 to -€24. A range of €211 to €43 was recorded between the highest and lowest ranked varieties within the updated PPI. Spearman's rank correlation between the updated and original PPI lists was 0.96. The introduction of the utilization subindex will allow farmers to make informed variety selection decisions when reseeding pasture, particularly on their grazing platforms and it will allow a demand-based communication process between the farmer and the grass merchant or breeder, ultimately affecting trait selection for future breeding strategies.
MeSH term(s)	Animal Feed/analysis ; Animals ; Dairying ; Diet ; Lactation ; Milk ; Plant Breeding
Language	English
Publishing date	2021-07-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	242499-x
ISSN	1525-3198 ; 0022-0302
ISSN (online)	1525-3198
ISSN	0022-0302
DOI	10.3168/jds.2021-20134
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Article ; Online: Mathematical models of drug-resistant tuberculosis lack bacterial heterogeneity: A systematic review.

Fuller, Naomi M / McQuaid, Christopher F / Harker, Martin J / Weerasuriya, Chathika K / McHugh, Timothy D / Knight, Gwenan M

PLoS pathogens

2024 Volume 20, Issue 4, Page(s) e1011574

Abstract: ... transmission models of non-treatment intervention impact in M. tuberculosis (n = 58). Studies were set ... in a limited number of specific countries, and 44% of models (n = 85) included only a single level ... of these also captured multiple antibiotic-resistant classes (n = 17), but six models included heterogeneity ...

Abstract	Drug-resistant tuberculosis (DR-TB) threatens progress in the control of TB. Mathematical models are increasingly being used to guide public health decisions on managing both antimicrobial resistance (AMR) and TB. It is important to consider bacterial heterogeneity in models as it can have consequences for predictions of resistance prevalence, which may affect decision-making. We conducted a systematic review of published mathematical models to determine the modelling landscape and to explore methods for including bacterial heterogeneity. Our first objective was to identify and analyse the general characteristics of mathematical models of DR-mycobacteria, including M. tuberculosis. The second objective was to analyse methods of including bacterial heterogeneity in these models. We had different definitions of heterogeneity depending on the model level. For between-host models of mycobacterium, heterogeneity was defined as any model where bacteria of the same resistance level were further differentiated. For bacterial population models, heterogeneity was defined as having multiple distinct resistant populations. The search was conducted following PRISMA guidelines in five databases, with studies included if they were mechanistic or simulation models of DR-mycobacteria. We identified 195 studies modelling DR-mycobacteria, with most being dynamic transmission models of non-treatment intervention impact in M. tuberculosis (n = 58). Studies were set in a limited number of specific countries, and 44% of models (n = 85) included only a single level of "multidrug-resistance (MDR)". Only 23 models (8 between-host) included any bacterial heterogeneity. Most of these also captured multiple antibiotic-resistant classes (n = 17), but six models included heterogeneity in bacterial populations resistant to a single antibiotic. Heterogeneity was usually represented by different fitness values for bacteria resistant to the same antibiotic (61%, n = 14). A large and growing body of mathematical models of DR-mycobacterium is being used to explore intervention impact to support policy as well as theoretical explorations of resistance dynamics. However, the majority lack bacterial heterogeneity, suggesting that important evolutionary effects may be missed.
Language	English
Publishing date	2024-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2205412-1
ISSN	1553-7374 ; 1553-7374
ISSN (online)	1553-7374
ISSN	1553-7374
DOI	10.1371/journal.ppat.1011574
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Examining the complementarity between the ERIC compilation of implementation strategies and the behaviour change technique taxonomy: a qualitative analysis.

McHugh, Sheena / Presseau, Justin / Luecking, Courtney T / Powell, Byron J

Implementation science : IS

2022 Volume 17, Issue 1, Page(s) 56

Abstract: ... with 'restructuring the social environment' as the most frequently coded (n=18 strategies, 25%). There was direct ... physical environment'). Most strategy descriptions (n=64) had BCTs that were clearly indicated (n=18), and ... others where BCTs were probable but not explicitly described (n=31) or indicated multiple types ...

Abstract	Background: Efforts to generate evidence for implementation strategies are frustrated by insufficient description. The Expert Recommendations for Implementing Change (ERIC) compilation names and defines implementation strategies; however, further work is needed to describe the actions involved. One potentially complementary taxonomy is the behaviour change techniques (BCT) taxonomy. We aimed to examine the extent and nature of the overlap between these taxonomies. Methods: Definitions and descriptions of 73 strategies in the ERIC compilation were analysed. First, each description was deductively coded using the BCT taxonomy. Second, a typology was developed to categorise the extent of overlap between ERIC strategies and BCTs. Third, three implementation scientists independently rated their level of agreement with the categorisation and BCT coding. Finally, discrepancies were settled through online consensus discussions. Additional patterns of complementarity between ERIC strategies and BCTs were labelled thematically. Descriptive statistics summarise the frequency of coded BCTs and the number of strategies mapped to each of the categories of the typology. Results: Across the 73 strategies, 41/93 BCTs (44%) were coded, with 'restructuring the social environment' as the most frequently coded (n=18 strategies, 25%). There was direct overlap between one strategy (change physical structure and equipment) and one BCT ('restructuring physical environment'). Most strategy descriptions (n=64) had BCTs that were clearly indicated (n=18), and others where BCTs were probable but not explicitly described (n=31) or indicated multiple types of overlap (n=15). For some strategies, the presence of additional BCTs was dependent on the form of delivery. Some strategies served as examples of broad BCTs operationalised for implementation. For eight strategies, there were no BCTs indicated, or they did not appear to focus on changing behaviour. These strategies reflected preparatory stages and targeted collective cognition at the system level rather than behaviour change at the service delivery level. Conclusions: This study demonstrates how the ERIC compilation and BCT taxonomy can be integrated to specify active ingredients, providing an opportunity to better understand mechanisms of action. Our results highlight complementarity rather than redundancy. More efforts to integrate these or other taxonomies will aid strategy developers and build links between existing silos in implementation science.
MeSH term(s)	Behavior Therapy/methods ; Consensus ; Humans
Language	English
Publishing date	2022-08-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2225822-X
ISSN	1748-5908 ; 1748-5908
ISSN (online)	1748-5908
ISSN	1748-5908
DOI	10.1186/s13012-022-01227-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: From Preconception Care to the First Day of School: Transforming the Health of New Families With Lifestyle Medicine.

McHugh, John / Dalal, Michelle / Agarwal, Neeta

American journal of lifestyle medicine

2020 Volume 14, Issue 5, Page(s) 532–540

Abstract: Lifestyle medicine holds great promise to transform health during the period from preconception to early childhood. Genetic, epigenetic, nutritional, and environmental factors have lifetime impact on the newborn and family. Little is known about the full ...

Abstract	Lifestyle medicine holds great promise to transform health during the period from preconception to early childhood. Genetic, epigenetic, nutritional, and environmental factors have lifetime impact on the newborn and family. Little is known about the full potential of lifestyle medicine to improve maternal, child, and family health. Additionally, health care providers face limits in time and may have gaps in knowledge, that preclude discussion of the impact lifestyle medicine can the mother, newborn, and family. Greater understanding of the potential impact of lifestyle medicine provides opportunities to identify current deficiencies in care and areas for improvement and highlights the need for further research. This article reviews current evidence supporting the 6 pillars of lifestyle medicine: nutrition, physical activity, sleep, avoiding risky substance use, stress management and social connectedness as applied to maternal child care from preconception to early childhood, examines the current state of practice, and identifies opportunities for both practice change and further research. Rather than view each component of care in isolation, viewing care as a continuum from preconception to childhood can best establish healthy habits and optimize outcomes for the entire family.
Language	English
Publishing date	2020-05-18
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2265653-4
ISSN	1559-8284 ; 1559-8276
ISSN (online)	1559-8284
ISSN	1559-8276
DOI	10.1177/1559827620912703
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