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  1. Article ; Online: Editorial [Hot topic: Tissue fibrosis (Guest editor: Shizuya Saika)].

    Saika, Shizuya

    Endocrine, metabolic & immune disorders drug targets

    2011  Volume 10, Issue 4, Page(s) 301

    MeSH term(s) Animals ; Cicatrix/etiology ; Cicatrix/metabolism ; Cicatrix/pathology ; Cicatrix/prevention & control ; Fibrosis ; Humans ; Signal Transduction ; Wound Healing
    Language English
    Publishing date 2011-01-05
    Publishing country United Arab Emirates
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2228325-0
    ISSN 2212-3873 ; 1871-5303
    ISSN (online) 2212-3873
    ISSN 1871-5303
    DOI 10.2174/1871530311006040301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Transient receptor potential ion channel family has come on to the front stage in the eye research field.

    Saika, Shizuya

    Taiwan journal of ophthalmology

    2020  Volume 10, Issue 2, Page(s) 77–79

    Language English
    Publishing date 2020-06-02
    Publishing country India
    Document type Editorial
    ISSN 2211-5072
    ISSN (online) 2211-5072
    DOI 10.4103/tjo.tjo_14_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Conjunctival Chalasis Should Not be Overlooked: Investigation Into Postoperative Ocular Surface Changes in Involutional Blepharoptosis.

    Uemura, Kazuhisa / Hiroki, Iwanishi / Saika, Shizuya / Suzuki, Takuya / Asamura, Shinichi

    The Journal of craniofacial surgery

    2024  

    Abstract: Background: Involutional blepharoptosis is common among elderly people. The tightening of eyelids postptosis surgery could potentially increase friction between the eyelid and the ocular surface, but this hypothesis has not yet been substantiated by ... ...

    Abstract Background: Involutional blepharoptosis is common among elderly people. The tightening of eyelids postptosis surgery could potentially increase friction between the eyelid and the ocular surface, but this hypothesis has not yet been substantiated by research. The authors explored the relationship between involutional blepharoptosis surgery and friction-related diseases, namely conjunctivochalasis, lid wiper epitheliopathy, and superior limbic keratoconjunctivitis.
    Methods: We conducted a prospective study involving 31 patients who underwent levator advancement for involutional blepharoptosis. Both preoperatively and 6 weeks postoperatively, the authors assessed a range of outcome measures, including margin reflex distance-1, 2, tear film break-up time, superficial punctate keratopathy, inferior conjunctivochalasis, upper lid wiper epitheliopathy, and superior limbic keratoconjunctivitis.
    Results: Conjunctivochalasis was detected in 18 eyes preoperatively and 20 eyes postoperatively. Lid wiper epitheliopathy was detected in 2 eyes preoperatively and in no eyes postoperatively. Superior limbic keratoconjunctivitis was detected in 2 eyes preoperatively and 1 eye postoperatively. From preoperative to postoperative assessments, conjunctivochalasis worsened in 11 eyes (17.2%), and there were no eyes with worsening lid wiper epitheliopathy or superior limbic keratoconjunctivitis. There was a significant worsening of superficial punctate keratopathy in the group with exacerbated conjunctivochalasis compared with the unchanged group (0.72 vs. 0.12, P=0.0222). The superficial petechial keratopathy in the 6 cases in which there was worsening of both conjunctivochalasis and superficial petechial keratopathy were all located inferiorly in the cornea.
    Conclusions: Conjunctivochalasis can worsen following ptosis surgery, potentially leading to an increase in inferior superficial punctate keratopathy. When performing involutional blepharoptosis surgery, surgeons should be mindful of the potential implications of friction-related diseases, particularly conjunctivochalasis.
    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000010168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: TGF-β signalling pathways and their enigmatic role as a friend and foe in human health and diseases.

    Betapudi, Venkaiah / Patro, Birija Sankar / Saika, Shizuya / Rahaman, Shaik O

    Frontiers in molecular biosciences

    2023  Volume 10, Page(s) 1232454

    Language English
    Publishing date 2023-06-20
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2023.1232454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Study to the Effect of Involutional Blepharoptosis Surgery Using Objective and Subjective Parameters.

    Asamura, Shinichi / Wada, Yoshitaka / Tanaka, Saiichi / Saika, Shizuya

    Archives of plastic surgery

    2022  Volume 49, Issue 4, Page(s) 473–478

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2022-07-30
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2694943-X
    ISSN 2234-6171 ; 2234-6163
    ISSN (online) 2234-6171
    ISSN 2234-6163
    DOI 10.1055/s-0042-1751101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Lens epithelium and posterior capsular opacification

    Saika, Shizuya / Werner, Liliana / Lovicu, Frank James

    2014  

    Author's details Shizuya Saika ; Liliana Werner ; Frank J. Lovicu ed
    Keywords Crystalline lens/Diseases ; Intraocular lenses/Complications ; Epithelial cells/Diseases
    Subject code 617.742
    Language English
    Size XVII, 424 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place Tokyo u.a.
    Publishing country Japan
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018384283
    ISBN 978-4-431-54299-5 ; 4-431-54299-X ; 9784431543008 ; 4431543007
    Database Catalogue ZB MED Medicine, Health

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  7. Article: A Glaucoma Patient with an Intraocular Pressure Decrease following Total Gastrectomy and Postoperative Anticancer Treatment.

    Takada, Yukihisa / Sumioka, Takayoshi / Tamura, Tadahiko / Saika, Shizuya

    Case reports in ophthalmological medicine

    2023  Volume 2023, Page(s) 9529229

    Abstract: We herein report a case of glaucoma with an intraocular pressure (IOP) decrease following total gastrectomy (TG) and anticancer treatment for gastric cancer. A 62-year-old male underwent trabeculectomy of the left and right eyes in August 2011 and July ... ...

    Abstract We herein report a case of glaucoma with an intraocular pressure (IOP) decrease following total gastrectomy (TG) and anticancer treatment for gastric cancer. A 62-year-old male underwent trabeculectomy of the left and right eyes in August 2011 and July 2012, respectively. During the follow-up, IOP of the right eye was 9-12 mmHg (with bimatoprost, dorzolamide, and timolol maleate), and that of the left eye ranged between 14 and 26 mmHg (with bimatoprost, dorzolamide, timolol maleate, and brimonidine tartrate). In December 2014, TG was performed due to gastric cancer. After surgery, the patient received S-1+CDDP, weekly PAC, and CPT-11 therapies. The patient died on March X, 2017. Before TG, the body mass index (BMI) was 29.5 but decreased to 24.8 before the start of the two courses of weekly PAC therapy. IOP of the right eye was 6 mmHg (with bimatoprost), and that of the left eye was 10 mmHg (with bimatoprost, dorzolamide, and brimonidine tartrate), showing decreases. After the initiation of weekly PAC therapy, BMI was approximately 19. IOP of the right eye ranged between 6 and 10 mmHg until the final ophthalmological examination (January 11, 2017), while that of the left eye ranged between 8 and 15 mmHg. In this patient with glaucoma, IOP was not controlled by eye drop treatment, and TG for gastric cancer and postoperative treatment with anticancer drugs resulted in weight loss and a decrease in IOP.
    Language English
    Publishing date 2023-02-14
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2659091-8
    ISSN 2090-6730 ; 2090-6722
    ISSN (online) 2090-6730
    ISSN 2090-6722
    DOI 10.1155/2023/9529229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Safety and Pitfalls of Blepharoptosis Surgery in Elderly People.

    Shirakawa, Yuji / Uemura, Kazuhisa / Kumegawa, Shinji / Ueno, Kazuki / Iwanishi, Hiroki / Saika, Shizuya / Asamura, Shinichi

    Archives of plastic surgery

    2023  Volume 50, Issue 5, Page(s) 446–451

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2023-08-28
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2694943-X
    ISSN 2234-6171 ; 2234-6163
    ISSN (online) 2234-6171
    ISSN 2234-6163
    DOI 10.1055/s-0043-1770082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Preface the 2nd Wakayama symposium: current concepts in ocular cell biology.

    Saika, Shizuya

    BMC ophthalmology

    2015  Volume 15 Suppl 1, Page(s) 164

    MeSH term(s) Cell Biology ; Congresses as Topic ; Corneal Diseases/physiopathology ; Humans
    Language English
    Publishing date 2015-12-17
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2050436-6
    ISSN 1471-2415 ; 1471-2415
    ISSN (online) 1471-2415
    ISSN 1471-2415
    DOI 10.1186/s12886-015-0156-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Editorial: New Insights into Mechanotransduction by Immune Cells in Physiological and Pathological Conditions.

    Saika, Shizuya / Veldhuis, Nicholas / Križaj, David / Rahaman, Shaik O

    Frontiers in immunology

    2022  Volume 13, Page(s) 930362

    MeSH term(s) Ion Channels/metabolism ; Mechanotransduction, Cellular/physiology
    Chemical Substances Ion Channels
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.930362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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