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  1. Article ; Online: Reforming China’s fertilizer policies: implications for nitrogen pollution reduction and food security [Correction: Jan. 2023, 18(1), p. 421-424]

    Wang, Xiaoxi / Xu, Meng / Lin, Bin / Bodirsky, Benjamin Leon / Xuan, Jiaqi / Dietrich, Jan Philipp / Stevanović, Miodrag / Bai, Zhaohai / Ma, Lin / Jin, Shuqin / Fan, Shenggen / Lotze-Campen, Hermann / Popp, Alexander

    Sustain Sci. 2023 Jan., v. 18, no. 1, p. 407-420

    2023  , Page(s) 407–420

    Abstract: Reactive nitrogen (N) is a requisite nutrient for agricultural production, but results in greenhouse gas and air and water pollution. The environmental and economic impacts of N fertilizer use in China are particularly relevant, as China consumes the ... ...

    Abstract Reactive nitrogen (N) is a requisite nutrient for agricultural production, but results in greenhouse gas and air and water pollution. The environmental and economic impacts of N fertilizer use in China are particularly relevant, as China consumes the largest amount of N fertilizer in the world to meet its soaring food demand. Here, we use an agro-economic land system model (MAgPIE) in combination with a difference-in-differences econometric model to provide a forward-looking assessment of China’s fertilizer policies in terms of removing fertilizer manufacturing subsidies and implementing measures to improve agricultural nutrient management efficiency. Our model results indicate that enhancing soil N uptake efficiency and manure recycled to soil alongside fertilizer subsidy removal can largely reduce N fertilizer use and N losses and abate N pollution in the short and long term, while food security remains largely unaffected. Enhancing soil N uptake efficiency appears to be decisive to achieving China’s national strategic target of zero growth in N fertilizer use. This study also finds that improving agricultural nutrient management efficiency contributes to higher land productivity and less cropland expansion, with substantial benefits for the environment and food security.
    Keywords air ; cropland ; econometric models ; fertilizer application ; food security ; greenhouse gases ; land productivity ; nitrogen ; nitrogen fertilizers ; nutrient management ; soil ; water pollution ; China
    Language English
    Dates of publication 2023-01
    Size p. 407-420
    Publishing place Springer Japan
    Document type Article ; Online
    ZDB-ID 2260333-5
    ISSN 1862-4057 ; 1862-4065
    ISSN (online) 1862-4057
    ISSN 1862-4065
    DOI 10.1007/s11625-022-01189-w
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Patterns of Deterioration in Moderate Patients With COVID-19 From Jan 2020 to Mar 2020: A Multi-Center, Retrospective Cohort Study in China.

    Chen, Sheng-Long / Feng, Hui-Ying / Xu, Hui / Huang, Shan-Shan / Sun, Jiu-Feng / Zhou, Lin / He, Jun-Lei / Song, Wen-Liang / Wang, Rui-Jie / Li, Xin / Fang, Ming

    Frontiers in medicine

    2020  Volume 7, Page(s) 567296

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2020-12-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2020.567296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Patterns of Deterioration in Moderate Patients With COVID-19 From Jan 2020 to Mar 2020

    Sheng-long Chen / Hui-ying Feng / Hui Xu / Shan-shan Huang / Jiu-feng Sun / Lin Zhou / Jun-lei He / Wen-liang Song / Rui-jie Wang / Xin Li / Ming Fang

    Frontiers in Medicine, Vol

    A Multi-Center, Retrospective Cohort Study in China

    2020  Volume 7

    Abstract: Background: Around the globe, moderate cases account for the largest proportion of all coronavirus disease 2019 (COVID-19) patients, and deteriorated moderate patients contribute the most in mortality. However, published articles failed to address the ... ...

    Abstract Background: Around the globe, moderate cases account for the largest proportion of all coronavirus disease 2019 (COVID-19) patients, and deteriorated moderate patients contribute the most in mortality. However, published articles failed to address the deterioration details of moderate cases, especially on when and how they deteriorated.Methods: All moderate COVID-19 patients hospitalized in Guangdong Province from January 14 to March 16, 2020, were included in this multicenter retrospective cohort study and were divided into deteriorated and non-deteriorated groups according to clinical status. Symptoms and demographic, therapeutic, and laboratory test result characteristics were collected to explore the features of disease deterioration.Results: Of 1,168 moderate patients included, 148 (13%) deteriorated to severe (130 cases) or critical (18 cases) status. Over 20% of the older subgroup (>50 years old) showed deterioration. The median time for deterioration was 11 days after onset [interquartile range (IQR) 9–14 days]. In addition, 12.2% severe cases could further develop to critical status after 3 days (IQR 2–6.5 days) of having a severe condition. Respiratory dysfunction and hypoxia were the major manifestations as disease deterioration, while 76 cases (52.1%) showed respiratory rate >30 breaths/min, 119 cases (80.4%) showed SaO2 <93%, 100 cases (67.5%) had 201 < PaO2/FiO2 < 300, and 27 cases (18.9%) had blood lactic acid >2.0 mmol/L. In view of multiple organ dysfunction, 87.8% of acute respiratory distress syndrome (ARDS), 20.2% of acute kidney injury (AKI), 6.8% of coagulopathy, 4% of acute heart failure (AHF), 3.4% of acute hepatic injury (AHI), and 5.4% of shock occurred in deteriorated patients, while organ injury occurred in the following sequence: ARDS, AKI, AHF, coagulopathy, AHI, and shock.Conclusions: The deteriorated pattern of moderate COVID-19 patients is characterized as the 11th day from onset (IQR 9–14 days) being an important time point of disease deterioration with further ...
    Keywords COVID-19 ; moderate ; deterioration ; time point ; pattern ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Corrigendum to "Efficacy of lianhuaqingwen granules in the management of chronic rhinosinusitis without nasal polyps" [Am. J. Otolaryngol. 2020 Jan - Feb;41(1):102311].

    Lin, L / Dai, F / Ren, G / Wei, J / Chen, Z / Tang, X

    American journal of otolaryngology

    2020  Volume 41, Issue 4, Page(s) 102510

    Language English
    Publishing date 2020-05-05
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2020.102510
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Exposure assessment of aflatoxins and zearalenone in edible vegetable oils in Shandong, China: health risks posed by mycotoxin immunotoxicity and reproductive toxicity in children [Correction: Jan. 2023, 30(2), p. 3759]

    Li, Fenghua / Zhao, Xianqi / Jiao, Yanni / Duan, Xinglan / Yu, Lianlong / Zheng, Fengjia / Wang, Xiaolin / Wang, Lin / Wang, Jia-Sheng / Zhao, Xiulan / Zhang, Tianliang / Li, Wei / Zhou, Jun

    Environ Sci Pollut Res. 2023 Jan., v. 30, no. 2, p. 3743-3758

    2023  , Page(s) 3743–3758

    Abstract: Human exposure to aflatoxins (AFs) and zearalenone (ZEA) has not been sufficiently investigated. Here, we analyzed the exposure level and health risks posed by AFs (B1, B2, G1, G2) and ZEA through cooking oil consumption in Shandong, China. The ... ...

    Abstract Human exposure to aflatoxins (AFs) and zearalenone (ZEA) has not been sufficiently investigated. Here, we analyzed the exposure level and health risks posed by AFs (B1, B2, G1, G2) and ZEA through cooking oil consumption in Shandong, China. The individual daily consumption of cooking oil was calculated through 2745 questionnaires during 2017–2019. The average contamination levels of mycotoxins were estimated by examining 60 cooking oil samples. For the peanut oil, AFs ranged from <0.2 to 274 μg/kg, with a positive rate of 66.6% (20/30). Average levels of 36.62 μg/kg AFB₁ and 44.43 μg/kg total AFs were found. Over-the-limit level (20 μg/kg) of AFB₁ was detected in 8/30 samples. Estimated daily intake (EDI) and margin of exposure (MOE) for age-stratified population groups showed that children are facing highest adverse health risk with AFB₁ (MOE 5.88–6.39). The liver cancer incidences attributable to AFB₁ exposure are non-negligible as 0.896, 0.825, and 0.767 cases per 100,000 for 6–14 age group, 15–17 age group, and adult labor-intensive workers. Over-the-limit level (60 μg/kg) ZEA contamination was detected in 25/30 corn oil samples with a 50th percentile value of 97.95 μg/kg. Our health risk assessment suggested significant health risks of enterohepatic (inflammation and cancer), reproductive, and endocrine systems posed by AFs and ZEA. However, the health risk of immunotoxicity is unclear because currently animal study data are not available for the immunotoxicity induced after long-term exposure. In general, the health risks posed by mycotoxins are non-negligible and long-term mycotoxin surveillance is necessary.
    Keywords adults ; aflatoxins ; average daily intake ; chronic exposure ; corn oil ; health effects assessments ; humans ; immunotoxicity ; inflammation ; liver neoplasms ; monitoring ; peanut oil ; reproductive toxicology ; risk ; vegetables ; zearalenone ; China
    Language English
    Dates of publication 2023-01
    Size p. 3743-3758
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-22385-2
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Corrigendum to "Surgical outcomes of robotic transanal minimally invasive surgery for selected rectal neoplasms: A single-hospital experience" [Asian J Surg. 43 (1) (2020 Jan) 290-296].

    Huang, Yan-Jiun / Huang, Yu-Min / Wang, Wei-Lin / Tong, Yiu-Shun / Hsu, Wayne / Wei, Po-Li

    Asian journal of surgery

    2021  Volume 44, Issue 2, Page(s) 525

    Language English
    Publishing date 2021-02-05
    Publishing country China
    Document type Published Erratum
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2020.12.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Top-down NOx emission changes in China using TROPOMI NO2 data from Jan 1 to Mar 12, 2020

    Zhang, Ruixiong / Zhang, Yuzhong / Lin, Haipeng / Feng, Xu / Fu, Tzung-May / Wang, Yuhang

    2020  

    Abstract: This datasets contains the top-down NOx emission data during Jan 1 - Mar 12, 2020, derived ... Zhang, Y.; Lin, H.; Feng, X.; Fu, T.-M.; Wang, Y. NOx Emission Reduction and Recovery during COVID-19 ...

    Abstract This datasets contains the top-down NOx emission data during Jan 1 - Mar 12, 2020, derived in the paper NOx emission reduction and recovery during COVID-19 in East China (https://www.mdpi.com/2073-4433/11/4/433). The top-down NOx emission changes can be used as a measure to assess the socioeconomic activity changes due to COVID-19 control measures. Data Description: regional_emission_changes_TableS1.xlsx: The derived NOx emission changes in China at regional (East China), provincial, and city (Wuhan) levels. regional_emission_timeseries.zip: The timeseries plots of NOx emission changes in the mentioned regions NO2_VCD_NOx_emission.nc: This contains data used to derive the top-down NOx emissions (at 0.05 degree resolution): NO2 data from TROPOMI and WRF-GC; NOx emissions from MEIC emission inventory. How to Cite: Please cite both the Zenodo dataset and the paper (https://www.mdpi.com/2073-4433/11/4/433, Zhang, R.; Zhang, Y.; Lin, H.; Feng, X.; Fu, T.-M.; Wang, Y. NOx Emission Reduction and Recovery during COVID-19 in East China. Atmosphere 2020, 11, 433.). Contact: If you have questions, please contact the corresponding authors Drs. Ruixiong Zhang (zhangruixiong@gmail.com) and Yuzhong Zhang (zhangyuzhong@westlake.edu.cn). Paper Abstract: Since its first confirmed case at the end of 2019, COVID-19 has become a global pandemic in three months with more than 1.4 million confirmed cases worldwide, as of early April 2020. Quantifying the changes of pollutant emissions due to COVID-19 and associated governmental control measures is crucial to understand its impacts on economy, air pollution, and society. We used the WRF-GC model and the tropospheric NO2 column observations retrieved by the TROPOMI instrument to derive the top-down NOx emission change estimation between the three periods: P1 (January 1st – January 22nd, 2020), P2 (January 23rd, Wuhan lockdown – February 9th, 2020), and P3 (February 10th, back-to-work day – March 12th, 2020). We found that NOx emissions in East China averaged during P2 decreased by 50% compared to those averaged during P1. The NOx emissions averaged during P3 increased by 26% compared to those during P2. Most provinces in East China gradually regained some of their NOx emissions after February 10, the official back-to-work day, but NOx emissions in most provinces has not yet to return to their previous levels in early January. NOx emissions in Wuhan, the first epicenter of COVID-19, had no sign of emission recovering by March 12. A few provinces, such as Zhejiang and Shanxi, have recovered fast, with their averaged NOx emissions during P3 almost back to pre-lockdown levels.
    Keywords NOx emission ; TROPOMI ; China ; COVID-19 ; Environment ; Air quality ; covid19
    Subject code 950
    Publishing date 2020-04-22
    Publishing country eu
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Proteomics analysis reveals the importance of transcriptional regulator slyA in regulation of several physiological functions in Aeromonas hydrophila [Corrigendum: Jan. 2022, v. 250, p. 104390]

    Li, Zhen / Zhang, Lishan / Sun, Lina / Wang, Yuqian / Chen, Jiazhen / Tang, Huamei / Lin, Ling / Lin, Xiangmin

    Journal of proteomics. 2021 July 30, v. 244, p. 104275

    2021  , Page(s) 104275

    Abstract: SlyA is a well-known transcription factor that plays important roles in the regulation of diverse physiological functions including virulence and stress response in various bacterial species. The biological effects of slyA have species-specific ... ...

    Abstract SlyA is a well-known transcription factor that plays important roles in the regulation of diverse physiological functions including virulence and stress response in various bacterial species. The biological effects of slyA have species-specific characteristics. In this study, a phenotype assay showed that slyA gene deletion in Aeromonas hydrophila (ahslyA) decreased biofilm formation capability but did not affect bacterial hemolytic activity or acid stress response. The differentially expressed proteins between ΔahslyA and wild-type strains were compared by label-free quantitative proteomics to further understand the effects of AhSlyA on biological functions. Bioinformatics assays showed that ΔahslyA may be involved in the regulation of several intracellular metabolic pathways such as galactose metabolism, arginine biosynthesis, and sulfur metabolism. A further phenotypic assay confirmed that AhSlyA plays an important role in the regulation of sulfur and phosphate metabolism. Moreover, ahslyA also directly or indirectly regulated at least eight outer membrane proteins involved in the maintenance of cell permeability. Overall, the results provide insights into the functions of ahslyA and demonstrate its importance in A. hydrophila.In this study, we compared the DEPs between the transcriptional regulator slyA-deleted and the wild-type A. hydrophila strains using a label-free quantitative proteomics method. The bioinformatics analysis showed that slyA may be involved in the regulation of several metabolic pathways. Subsequent phenotype and growth assays confirmed that ΔahslyA affected sulfur and phosphate metabolism, and OM permeability. Finally, a ChIP-PCR assay further confirmed that AhSlyA directly binds to the promoters of several candidate genes, including sulfur metabolism-related genes. These results indicated that slyA plays an important regulatory role in pleiotropic physiological functions of A. hydrophila, and these functions may be different from those identified in previous reports from other bacterial species.
    Keywords Aeromonas hydrophila ; arginine ; biofilm ; bioinformatics ; biosynthesis ; galactose ; gene deletion ; gene expression regulation ; hemolysis ; permeability ; phenotype ; phosphates ; proteomics ; stress response ; sulfur ; transcription factors ; virulence ; slyA ; Proteomics ; Sulfur metabolism ; Outer membrane permeability
    Language English
    Dates of publication 2021-0730
    Size p. 104275
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 2400835-7
    ISSN 1876-7737 ; 1874-3919
    ISSN (online) 1876-7737
    ISSN 1874-3919
    DOI 10.1016/j.jprot.2021.104275
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Corrigendum to "N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression"[Eur. J. Med. Chem. 2020 Jan 1;185:111725].

    Mehndiratta, Samir / Lin, Mei-Hsiang / Wu, Yi-Wen / Chen, Chun-Han / Wu, Tung-Yun / Chuang, Kuo-Hsiang / Chao, Min-Wu / Chen, Yi-Ying / Pan, Shiow-Lin / Chen, Mei-Chuan / Liou, Jing-Ping

    European journal of medicinal chemistry

    2020  Volume 199, Page(s) 112406

    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country France
    Document type Journal Article ; Published Erratum
    ZDB-ID 188597-2
    ISSN 1768-3254 ; 0009-4374 ; 0223-5234
    ISSN (online) 1768-3254
    ISSN 0009-4374 ; 0223-5234
    DOI 10.1016/j.ejmech.2020.112406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Corrigendum to "N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression"[Eur. J. Med. Chem. 2020 Jan 1;185:111725]

    Mehndiratta, Samir / Lin, Mei-Hsiang / Wu, Yi-Wen / Chen, Chun-Han / Wu, Tung-Yun / Chuang, Kuo-Hsiang / Chao, Min-Wu / Chen, Yi-Ying / Pan, Shiow-Lin / Chen, Mei-Chuan / Liou, Jing-Ping

    Eur J Med Chem

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32408215
    Database COVID19

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