Article ; Online: TRP channels in COVID-19 disease: Potential targets for prevention and treatment.
Chemico-biological interactions
2021 Volume 345, Page(s) 109567
Abstract: Coronavirus disease 2019 [COVID-19] is a global health threat caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins for entry: angiotensin-converting enzyme 2 [ACE2] and -membrane protease serine 2 [TMPRSS2]. ... ...
Abstract | Coronavirus disease 2019 [COVID-19] is a global health threat caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins for entry: angiotensin-converting enzyme 2 [ACE2] and -membrane protease serine 2 [TMPRSS2]. Many patients complain from pneumonia, cough, fever, and gastrointestinal (GI) problems. Notably, different TRP channels are expressed in various tissues infected by SARS-CoV-2. TRP channels are cation channels that show a common architecture with high permeability to calcium [Ca |
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MeSH term(s) | COVID-19/drug therapy ; COVID-19/metabolism ; COVID-19/prevention & control ; Humans ; Molecular Targeted Therapy ; Transient Receptor Potential Channels/metabolism |
Chemical Substances | Transient Receptor Potential Channels |
Language | English |
Publishing date | 2021-06-22 |
Publishing country | Ireland |
Document type | Journal Article ; Review |
ZDB-ID | 218799-1 |
ISSN | 1872-7786 ; 0009-2797 |
ISSN (online) | 1872-7786 |
ISSN | 0009-2797 |
DOI | 10.1016/j.cbi.2021.109567 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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