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Article ; Online: RE: Removal of small, asymptomatic kidney stones and incidence of relapse.

Boeykens, Matthias / Van Haute, Carl / De Coninck, Vincent

2022 Volume 41, Issue 2, Page(s) 613–614

MeSH term(s)	Humans ; Incidence ; Kidney Calculi/epidemiology ; Kidney ; Recurrence
Language	English
Publishing date	2022-12-26
Publishing country	Germany
Document type	Letter ; Comment
ZDB-ID	380333-8
ISSN	1433-8726 ; 0724-4983
ISSN (online)	1433-8726
ISSN	0724-4983
DOI	10.1007/s00345-022-04251-5
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Article ; Online: Editorial on: In Vitro Effects of a Novel Coating Agent on Bacterial Biofilm Development on Ureteral Stents by Szell et al. (From: Szell T, Dressler FF, Goelz H, et al. J Endourol 2019;33:225-231; DOI: 10.1089/end.2018.0616).

Tailly, Thomas / Van Haute, Carl

Journal of endourology

2019 Volume 33, Issue 3, Page(s) 232–233

MeSH term(s)	Biofilms ; Stents ; Ureter
Language	English
Publishing date	2019-02-04
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	356931-7
ISSN	1557-900X ; 0892-7790
ISSN (online)	1557-900X
ISSN	0892-7790
DOI	10.1089/end.2018.0907
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Zs.A 2628: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: "Trust my morphology", the key message from a kidney stone.

Pozdzik, Agnieszka / Van Haute, Carl / Maalouf, Naim / Letavernier, Emmanuel / Williams, James C / Sakhaee, Khashayar

Urolithiasis

2021 Volume 49, Issue 5, Page(s) 493–494

MeSH term(s)	Humans ; Kidney Calculi ; Trust
Language	English
Publishing date	2021-07-23
Publishing country	Germany
Document type	Letter ; Comment
ZDB-ID	2703553-0
ISSN	2194-7236 ; 2194-7228
ISSN (online)	2194-7236
ISSN	2194-7228
DOI	10.1007/s00240-021-01280-4
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Article ; Online: Reusable, Single-Use, or Both: A Cost Efficiency Analysis of Flexible Ureterorenoscopes After 983 Cases.

Van Compernolle, Dries / Veys, Ralf / Elshout, Pieter Jan / Beysens, Matthias / Van Haute, Carl / De Groote, Laurent / Tailly, Thomas

Journal of endourology

2021 Volume 35, Issue 10, Page(s) 1454–1459

Abstract: Objectives: ...

Abstract	Objectives:
MeSH term(s)	Equipment Design ; Equipment Reuse ; Humans ; Kidney Calculi ; Retrospective Studies ; Ureteroscopes ; Ureteroscopy
Language	English
Publishing date	2021-05-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	356931-7
ISSN	1557-900X ; 0892-7790
ISSN (online)	1557-900X
ISSN	0892-7790
DOI	10.1089/end.2021.0006
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Article ; Online: Laparoscopic assisted mini-ECIRS for ectopic kidney lithiasis: A case report and literature review.

Amato, Marco / Piazza, Pietro / Deruyver, Yves / Del Favero, Lina / Van den Broeck, Thomas / Sarchi, Luca / Scarcella, Simone / Bravi, Carlo Andrea / Puliatti, Stefano / Micali, Salvatore / Van Haute, Carl / Van Cleynenbreugel, Ben

CEN case reports

2022 Volume 11, Issue 3, Page(s) 295–301

Abstract: Introduction: Ectopic kidney is a rare anatomic variant with an incidence of about 1 in 900. Renal stones can pose a challenge when a standard approach is not possible. Laparoscopic-assisted endourologic procedure can be a feasible and safe choice.: ... ...

Abstract	Introduction: Ectopic kidney is a rare anatomic variant with an incidence of about 1 in 900. Renal stones can pose a challenge when a standard approach is not possible. Laparoscopic-assisted endourologic procedure can be a feasible and safe choice. Case report and literature review: We present a case of 32 years old man with spastic quadriplegia, megacolon and pelvic kidney undergoing intervention of laparoscopic-assisted Mini ECIRS for staghorn stone of the left pelvic kidney. To the best of our knowledge, only 59 cases are reported in the literature concerning laparoscopically assisted encdourologic treatment which seems a feasible, safe and adaptable technique in selected complex cases. Conclusion: Laparoscopic-assisted mini ECIRS is a viable option for the treatment of ectopic kidney stones. This technique should be considered when anatomical anomalies are encountered, to avoid puncture-related complications.
MeSH term(s)	Adult ; Humans ; Kidney/abnormalities ; Kidney/diagnostic imaging ; Kidney/surgery ; Kidney Calculi/complications ; Kidney Calculi/diagnosis ; Kidney Calculi/surgery ; Laparoscopy ; Lithiasis/surgery ; Male ; Nephrostomy, Percutaneous/methods
Language	English
Publishing date	2022-01-04
Publishing country	Japan
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2660492-9
ISSN	2192-4449 ; 2192-4449
ISSN (online)	2192-4449
ISSN	2192-4449
DOI	10.1007/s13730-021-00683-x
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Article ; Online: Thiel-embalmed cadavers as a novel training model for ultrasound-guided supine endoscopic combined intrarenal surgery.

Veys, Ralf / Verpoort, Pieter / Van Haute, Carl / Wang, Zhan Tao / Chi, Thomas / Tailly, Thomas

BJU international

2019 Volume 125, Issue 4, Page(s) 579–585

Abstract: Objective: To evaluate Thiel-embalmed cadavers (TEC) as a training model for percutaneous nephrolithotomy (PCNL), more specifically for ultrasound (US)-guided supine endoscopic combined intrarenal surgery (ECIRS).: Subjects and methods: Thirteen ... ...

Abstract	Objective: To evaluate Thiel-embalmed cadavers (TEC) as a training model for percutaneous nephrolithotomy (PCNL), more specifically for ultrasound (US)-guided supine endoscopic combined intrarenal surgery (ECIRS). Subjects and methods: Thirteen urologists (nine experienced endourologists, four fellows/residents) performed an US-guided supine ECIRS procedure on a TEC. The model was evaluated by way of a questionnaire (5-point Likert scale). Descriptive statistical analysis was performed and results were graphically presented using divergent bar graphs. Results: US images were appreciated as lifelike in all aspects. Although distention of the collecting system was not ideal in one out of three TEC, US visualisation of the distended calyces during puncture was good. Skin penetration was more difficult and less realistic in TEC, while kidney puncture and dilatation were deemed very realistic. Ureteric and collecting system anatomy and consistency were similar to real life, although the mucosa appeared paler. US needle guidance was perceived as excellent. Overall, needle puncture assessment was realistic and useful as a training tool. Overall quality and satisfaction of TEC in US-guided supine ECIRS was good to excellent and comparable to a real-life procedure. Overall appropriateness of the TEC model was considered excellent for both initial and advanced supine PCNL training. Conclusion: Despite the minor drawbacks of tough skin and non-ideal collecting system dilatation during ureteroscopy, the TEC model was considered good to excellent as a training model for US-guided PCNL, in particular, US-guided needle puncture of the kidney during supine ECIRS.
MeSH term(s)	Cadaver ; Embalming/methods ; Female ; Humans ; Kidney/surgery ; Nephrolithotomy, Percutaneous/education ; Nephrolithotomy, Percutaneous/methods ; Patient Positioning ; Sulfhydryl Compounds ; Supine Position ; Surgery, Computer-Assisted ; Ultrasonography, Interventional ; Urology/education
Chemical Substances	Sulfhydryl Compounds
Language	English
Publishing date	2019-12-19
Publishing country	England
Document type	Journal Article
ZDB-ID	1462191-5
ISSN	1464-410X ; 1464-4096 ; 1358-8672
ISSN (online)	1464-410X
ISSN	1464-4096 ; 1358-8672
DOI	10.1111/bju.14954
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Ui VI Zs.107: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 13: Show issues

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Article ; Online: ARNEO: A Randomized Phase II Trial of Neoadjuvant Degarelix with or Without Apalutamide Prior to Radical Prostatectomy for High-risk Prostate Cancer.

Devos, Gaëtan / Tosco, Lorenzo / Baldewijns, Marcella / Gevaert, Thomas / Goffin, Karolien / Petit, Valentin / Mai, Cindy / Laenen, Annouschka / Raskin, Yannic / Van Haute, Carl / Goeman, Lieven / De Meerleer, Gert / Berghen, Charlien / Devlies, Wout / Claessens, Frank / Van Poppel, Hendrik / Everaerts, Wouter / Joniau, Steven

European urology

2022 Volume 83, Issue 6, Page(s) 508–518

Abstract: Background: High-risk prostate cancer (PCa) patients have a high risk of biochemical recurrence and metastatic progression following radical prostatectomy (RP).: Objective: To determine the efficacy of neoadjuvant degarelix plus apalutamide before RP ...

Abstract	Background: High-risk prostate cancer (PCa) patients have a high risk of biochemical recurrence and metastatic progression following radical prostatectomy (RP). Objective: To determine the efficacy of neoadjuvant degarelix plus apalutamide before RP compared with degarelix with a matching placebo. Design, setting, and participants: ARNEO was a randomized, placebo-controlled, phase II neoadjuvant trial before RP performed between March 2019 and April 2021. Eligible patients had high-risk PCa and were amenable to RP. Intervention: Patients were randomly assigned at a 1:1 ratio to degarelix (240-80-80 mg) + apalutamide (240 mg/d) versus degarelix + matching placebo for 3 mo followed by RP. Prior to and following neoadjuvant treatment, pelvic Outcome measurements and statistical analysis: The primary endpoint was the difference in proportions of patients with minimal residual disease (MRD; = residual cancer burden (RCB) ≤0.25 cm Results and limitations: Patients were randomized to neoadjuvant degarelix + apalutamide (n = 45) or degarelix + matching placebo (n = 44) for 12 wk and underwent RP. Patients in the degarelix + apalutamide arm achieved a significantly higher rate of MRD than those in the control arm (38% vs 9.1%; relative risk [95% confidence interval] = 4.2 [1.5-11], p = 0.002). Patients with PTEN loss in baseline prostate biopsy attained significantly less MRD (11% vs 43%, p = 0.002) and had a higher RCB at final pathology (1.6 vs 0.40 cm Conclusions: In high-risk PCa patients, neoadjuvant degarelix plus apalutamide prior to RP results in a significantly improved pathological response (MRD and RCB) compared with degarelix alone. Our trial results provide a solid hypothesis-generating basis for neoadjuvant phase 3 trials, which are powered to detect differences in long-term oncological outcome following neoadjuvant androgen receptor signaling inhibitor therapy. Patient summary: In this study, we looked at the difference in pathological responses in high-risk prostate cancer patients treated with degarelix plus apalutamide or degarelix plus matching placebo prior to radical prostatectomy. We demonstrated that patients treated with degarelix plus apalutamide achieved a significantly better tumor response than patients treated with degarelix plus matching placebo. Long-term follow-up is required to determine whether improved pathological outcome translates into better oncological outcomes.
MeSH term(s)	Male ; Humans ; Prostate/pathology ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/surgery ; Neoadjuvant Therapy/methods ; Prostatectomy/methods ; Gallium Radioisotopes
Chemical Substances	acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide ; apalutamide ; Gallium Radioisotopes
Language	English
Publishing date	2022-09-24
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Clinical Trial, Phase II ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	193790-x
ISSN	1873-7560 ; 1421-993X ; 0302-2838
ISSN (online)	1873-7560 ; 1421-993X
ISSN	0302-2838
DOI	10.1016/j.eururo.2022.09.009
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Zs.MO 294: Show issues

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Article ; Online: Meeting report of the "Symposium on kidney stones and mineral metabolism: calcium kidney stones in 2017".

Pozdzik, Agnieszka / Maalouf, Naim / Letavernier, Emmanuel / Brocheriou, Isabelle / Body, Jean-Jacques / Vervaet, Benjamin / Van Haute, Carl / Noels, Johanna / Gadisseur, Romy / Castiglione, Vincent / Cotton, Frédéric / Gambaro, Giovanni / Daudon, Michel / Sakhaee, Khashayar

Journal of nephrology

2019 Volume 32, Issue 5, Page(s) 681–698

Abstract: A symposium on kidney stones and mineral metabolism held on December 2017 in Brussels, Belgium was the first international multidisciplinary conference of the International Collaborative Network on Kidney Stones and Mineral Metabolism. This meeting ... ...

Abstract	A symposium on kidney stones and mineral metabolism held on December 2017 in Brussels, Belgium was the first international multidisciplinary conference of the International Collaborative Network on Kidney Stones and Mineral Metabolism. This meeting addressed epidemiology, underlying pathophysiological mechanisms, genetics, pathological, as well as clinical and research topics. The participants included clinicians and recognized experts in the field from Europe and the United States interacted closely during the symposium which promoted a chance to explore new frontiers in the field of kidney stone disease. This manuscript summarizes some of the major highlights of the meeting.
MeSH term(s)	Calcium/metabolism ; Crystallization ; Decision Trees ; Humans ; Kidney Calculi/epidemiology ; Kidney Calculi/etiology ; Kidney Calculi/metabolism ; Kidney Calculi/therapy ; Minerals/metabolism ; Nephrocalcinosis/genetics ; Nephrolithiasis/genetics
Chemical Substances	Minerals ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2019-01-24
Publishing country	Italy
Document type	Congress
ZDB-ID	1093991-x
ISSN	1724-6059 ; 1120-3625 ; 1121-8428
ISSN (online)	1724-6059
ISSN	1120-3625 ; 1121-8428
DOI	10.1007/s40620-019-00587-1
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Article ; Online: TRP channels in human prostate.

Van Haute, Carl / De Ridder, Dirk / Nilius, Bernd

TheScientificWorldJournal

2010 Volume 10, Page(s) 1597–1611

Abstract: This review gives an overview of morphological and functional characteristics in the human prostate. It will focus on the current knowledge about transient receptor potential (TRP) channels expressed in the human prostate, and their putative role in ... ...

Abstract	This review gives an overview of morphological and functional characteristics in the human prostate. It will focus on the current knowledge about transient receptor potential (TRP) channels expressed in the human prostate, and their putative role in normal physiology and prostate carcinogenesis. Controversial data regarding the expression pattern and the potential impact of TRP channels in prostate function, and their involvement in prostate cancer and other prostate diseases, will be discussed.
MeSH term(s)	Calcium Channels/genetics ; Calcium Channels/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Male ; Prostate/anatomy & histology ; Prostate/metabolism ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Reverse Transcriptase Polymerase Chain Reaction ; TRPM Cation Channels/genetics ; TRPM Cation Channels/metabolism ; TRPV Cation Channels/genetics ; TRPV Cation Channels/metabolism ; Transient Receptor Potential Channels/genetics ; Transient Receptor Potential Channels/metabolism
Chemical Substances	Calcium Channels ; TRPM Cation Channels ; TRPM8 protein, human ; TRPV Cation Channels ; TRPV6 protein, human ; Transient Receptor Potential Channels
Language	English
Publishing date	2010-08-17
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2075968-X
ISSN	1537-744X ; 1537-744X
ISSN (online)	1537-744X
ISSN	1537-744X
DOI	10.1100/tsw.2010.149
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Article ; Online: TRP Channels in Human Prostate

Carl Van Haute / Dirk De Ridder / Bernd Nilius

The Scientific World Journal, Vol 10, Pp 1597-

2010 Volume 1611

Abstract	This review gives an overview of morphological and functional characteristics in the human prostate. It will focus on the current knowledge about transient receptor potential (TRP) channels expressed in the human prostate, and their putative role in normal physiology and prostate carcinogenesis. Controversial data regarding the expression pattern and the potential impact of TRP channels in prostate function, and their involvement in prostate cancer and other prostate diseases, will be discussed.
Keywords	Science (General) ; Q1-390
Language	English
Publishing date	2010-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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