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  1. Article ; Online: Tectonic influence on Cenozoic mammal richness and sedimentation history of the Basin and Range, western North America.

    Loughney, Katharine M / Badgley, Catherine / Bahadori, Alireza / Holt, William E / Rasbury, E Troy

    Science advances

    2021  Volume 7, Issue 45, Page(s) eabh4470

    Abstract: Tectonic activity can drive speciation and sedimentation, potentially causing the fossil and rock records to share common patterns through time. The Basin and Range of western North America arose through widespread extension and collapse of topographic ... ...

    Abstract Tectonic activity can drive speciation and sedimentation, potentially causing the fossil and rock records to share common patterns through time. The Basin and Range of western North America arose through widespread extension and collapse of topographic highlands in the Miocene, creating numerous basins with rich mammalian fossil records. We analyzed patterns of mammalian species richness from 36 to 0 million years ago in relation to the history of sediment accumulation to test whether intervals of high species richness corresponded with elevated sediment accumulation and fossil burial in response to tectonic deformation. We found that the sedimentary record of the Basin and Range tracks the tectonic evolution of landscapes, whereas species-richness trends reflect actual increased richness in the Miocene rather than increased fossil burial. The sedimentary record of the region broadly determines the preservation of the fossil record but does not drive the Miocene peak in mammalian species richness.
    Language English
    Publishing date 2021-11-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.abh4470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Emergent properties of microbial communities drive accelerated biogeochemical cycling in disturbed temperate forests.

    Osburn, Ernest D / Badgley, Brian D / Strahm, Brian D / Aylward, Frank O / Barrett, J E

    Ecology

    2021  Volume 102, Issue 12, Page(s) e03553

    Abstract: ... specific processes (i.e., C- and N-mineralization), microbial metrics significantly improved models seeking ... these relationships at the Coweeta Hydrologic Laboratory, where past forest disturbances (e.g., clear-cut) have ... altered both ecosystem processes (e.g., increased N export) and microbial communities (e.g., increased ...

    Abstract Despite ever-increasing availability of detailed information about microbial community structure, relationships of microbial diversity with ecosystem functioning remain unclear. We investigated these relationships at the Coweeta Hydrologic Laboratory, where past forest disturbances (e.g., clear-cut) have altered both ecosystem processes (e.g., increased N export) and microbial communities (e.g., increased bacterial diversity). We sampled soils from disturbed and adjacent reference forests, characterized resident microbial communities, and measured several microbial C-cycle and N-cycle process rates. Microbial communities from historically disturbed soils exhibited altered ecosystem functioning, including generally higher rates of C- and N-cycle processes. Disturbed soil microbial communities also exhibited altered ecosystem multifunctionality, a composite variable consisting of all measured process rates as well as extracellular enzyme activities. Although we found few relationships between ecosystem functions and microbial alpha diversity, all functions were correlated with microbial community composition metrics, particularly r:K strategist ratios of bacterial phyla. Additionally, for both ecosystem multifunctionality and specific processes (i.e., C- and N-mineralization), microbial metrics significantly improved models seeking to explain variation in process rates. Our work sheds light on the links between microbial communities and ecosystem functioning and identifies specific microbial metrics important for modeling ecosystem responses to environmental change.
    MeSH term(s) Forests ; Microbiota ; Nitrogen/analysis ; Soil ; Soil Microbiology
    Chemical Substances Soil ; Nitrogen (N762921K75)
    Language English
    Publishing date 2021-11-05
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2010140-5
    ISSN 1939-9170 ; 0012-9658
    ISSN (online) 1939-9170
    ISSN 0012-9658
    DOI 10.1002/ecy.3553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Moisture-driven divergence in mineral-associated soil carbon persistence.

    Heckman, Katherine A / Possinger, Angela R / Badgley, Brian D / Bowman, Maggie M / Gallo, Adrian C / Hatten, Jeff A / Nave, Lucas E / SanClements, Michael D / Swanston, Christopher W / Weiglein, Tyler L / Wieder, William R / Strahm, Brian D

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 7, Page(s) e2210044120

    Abstract: Mineral stabilization of soil organic matter is an important regulator of the global carbon (C ... the abundance and persistence of mineral-associated organic C varied with climate at the continental scale ... In these humid soils, mineral-associated soil organic C concentration and persistence are strongly linked ...

    Abstract Mineral stabilization of soil organic matter is an important regulator of the global carbon (C) cycle. However, the vulnerability of mineral-stabilized organic matter (OM) to climate change is currently unknown. We examined soil profiles from 34 sites across the conterminous USA to investigate how the abundance and persistence of mineral-associated organic C varied with climate at the continental scale. Using a novel combination of radiocarbon and molecular composition measurements, we show that the relationship between the abundance and persistence of mineral-associated organic matter (MAOM) appears to be driven by moisture availability. In wetter climates where precipitation exceeds evapotranspiration, excess moisture leads to deeper and more prolonged periods of wetness, creating conditions which favor greater root abundance and also allow for greater diffusion and interaction of inputs with MAOM. In these humid soils, mineral-associated soil organic C concentration and persistence are strongly linked, whereas this relationship is absent in drier climates. In arid soils, root abundance is lower, and interaction of inputs with mineral surfaces is limited by shallower and briefer periods of moisture, resulting in a disconnect between concentration and persistence. Data suggest a tipping point in the cycling of mineral-associated C at a climate threshold where precipitation equals evaporation. As climate patterns shift, our findings emphasize that divergence in the mechanisms of OM persistence associated with historical climate legacies need to be considered in process-based models.
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2210044120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The treatment of intracapsular fractures of the neck of the femur.

    BADGLEY, C E

    The Surgical clinics of North America

    2003  Volume 41, Page(s) 1367–1377

    MeSH term(s) Child ; Femoral Neck Fractures ; Femur ; Femur Neck ; Humans ; Infant ; Neck
    Language English
    Publishing date 2003-05-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 215713-5
    ISSN 1558-3171 ; 0039-6109
    ISSN (online) 1558-3171
    ISSN 0039-6109
    DOI 10.1016/s0039-6109(16)36498-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Taphonomic information from the modern vertebrate death assemblage of Doñana National Park, Spain.

    Domingo, M Soledad / Martín-Perea, David M / Badgley, Catherine / Cantero, Enrique / López-Guerrero, Paloma / Oliver, Adriana / Negro, Juan José

    PloS one

    2020  Volume 15, Issue 11, Page(s) e0242082

    Abstract: Modern death assemblages provide insights about the early stages of fossilization and useful ecological information about the species inhabiting the ecosystem. We present the results of taphonomic monitoring of modern vertebrate carcasses and bones from ... ...

    Abstract Modern death assemblages provide insights about the early stages of fossilization and useful ecological information about the species inhabiting the ecosystem. We present the results of taphonomic monitoring of modern vertebrate carcasses and bones from Doñana National Park, a Mediterranean coastal ecosystem in Andalusia, Spain. Ten different habitats were surveyed. Half of them occur in active depositional environments (marshland, lake margin, river margin, beach and dunes). Most of the skeletal remains belong to land mammals larger than 5 kg in body weight (mainly wild and feral ungulates). Overall, the Doñana bone assemblage shows good preservation with little damage to the bones, partly as a consequence of the low predator pressure on large vertebrates. Assemblages from active depositional habitats differ significantly from other habitats in terms of the higher incidence of breakage and chewing marks on bones in the latter, which result from scavenging, mainly by wild boar and red fox. The lake-margin and river-margin death assemblages have high concentrations of well preserved bones that are undergoing burial and offer the greatest potential to produce fossil assemblages. The spatial distribution of species in the Doñana death assemblage generally reflects the preferred habitats of the species in life. Meadows seem to be a preferred winter habitat for male deer, given the high number of shed antlers recorded there. This study is further proof that taphonomy can provide powerful insights to better understand the ecology of modern species and to infer past and future scenarios for the fossil record.
    MeSH term(s) Animals ; Bone and Bones/anatomy & histology ; Demography ; Ecosystem ; Fossils/anatomy & histology ; Mammals/anatomy & histology ; Mammals/classification ; Paleontology ; Parks, Recreational ; Spain ; Species Specificity
    Language English
    Publishing date 2020-11-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0242082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Aseptic necrosis of the femoral head following fracture of the hip.

    BADGLEY, C E / DENHAM, R H

    Journal of the American Medical Association

    2006  Volume 137, Issue 14, Page(s) 1193–6; Disc, 1206–9

    MeSH term(s) Femur Head ; Femur Head Necrosis ; Fractures, Bone ; Hip ; Humans ; Necrosis ; Osteonecrosis
    Language English
    Publishing date 2006-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0002-9955 ; 0254-9077 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0002-9955 ; 0254-9077 ; 0098-7484
    DOI 10.1001/jama.1948.02890480013004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Emergent properties of microbial communities drive accelerated biogeochemical cycling in disturbed temperate forests

    Osburn, Ernest D. / Badgley, Brian D. / Strahm, Brian D. / Aylward, Frank O. / Barrett, J. E.

    Ecology. 2021 Dec., v. 102, no. 12

    2021  

    Abstract: ... specific processes (i.e., C‐ and N‐mineralization), microbial metrics significantly improved models seeking ... these relationships at the Coweeta Hydrologic Laboratory, where past forest disturbances (e.g., clear‐cut) have ... altered both ecosystem processes (e.g., increased N export) and microbial communities (e.g., increased ...

    Abstract Despite ever‐increasing availability of detailed information about microbial community structure, relationships of microbial diversity with ecosystem functioning remain unclear. We investigated these relationships at the Coweeta Hydrologic Laboratory, where past forest disturbances (e.g., clear‐cut) have altered both ecosystem processes (e.g., increased N export) and microbial communities (e.g., increased bacterial diversity). We sampled soils from disturbed and adjacent reference forests, characterized resident microbial communities, and measured several microbial C‐cycle and N‐cycle process rates. Microbial communities from historically disturbed soils exhibited altered ecosystem functioning, including generally higher rates of C‐ and N‐cycle processes. Disturbed soil microbial communities also exhibited altered ecosystem multifunctionality, a composite variable consisting of all measured process rates as well as extracellular enzyme activities. Although we found few relationships between ecosystem functions and microbial alpha diversity, all functions were correlated with microbial community composition metrics, particularly r:K strategist ratios of bacterial phyla. Additionally, for both ecosystem multifunctionality and specific processes (i.e., C‐ and N‐mineralization), microbial metrics significantly improved models seeking to explain variation in process rates. Our work sheds light on the links between microbial communities and ecosystem functioning and identifies specific microbial metrics important for modeling ecosystem responses to environmental change.
    Keywords clearcutting ; community structure ; disturbed soils ; ecosystems ; extracellular enzymes ; hydrology ; microbial communities ; mineralization ; nitrogen ; nitrogen cycle ; species diversity
    Language English
    Dates of publication 2021-12
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 1797-8
    ISSN 0012-9658
    ISSN 0012-9658
    DOI 10.1002/ecy.3553
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer.

    Wasko, Urszula N / Jiang, Jingjing / Dalton, Tanner C / Curiel-Garcia, Alvaro / Edwards, A Cole / Wang, Yingyun / Lee, Bianca / Orlen, Margo / Tian, Sha / Stalnecker, Clint A / Drizyte-Miller, Kristina / Menard, Marie / Dilly, Julien / Sastra, Stephen A / Palermo, Carmine F / Hasselluhn, Marie C / Decker-Farrell, Amanda R / Chang, Stephanie / Jiang, Lingyan /
    Wei, Xing / Yang, Yu C / Helland, Ciara / Courtney, Haley / Gindin, Yevgeniy / Muonio, Karl / Zhao, Ruiping / Kemp, Samantha B / Clendenin, Cynthia / Sor, Rina / Vostrejs, William P / Hibshman, Priya S / Amparo, Amber M / Hennessey, Connor / Rees, Matthew G / Ronan, Melissa M / Roth, Jennifer A / Brodbeck, Jens / Tomassoni, Lorenzo / Bakir, Basil / Socci, Nicholas D / Herring, Laura E / Barker, Natalie K / Wang, Junning / Cleary, James M / Wolpin, Brian M / Chabot, John A / Kluger, Michael D / Manji, Gulam A / Tsai, Kenneth Y / Sekulic, Miroslav / Lagana, Stephen M / Califano, Andrea / Quintana, Elsa / Wang, Zhengping / Smith, Jacqueline A M / Holderfield, Matthew / Wildes, David / Lowe, Scott W / Badgley, Michael A / Aguirre, Andrew J / Vonderheide, Robert H / Stanger, Ben Z / Baslan, Timour / Der, Channing J / Singh, Mallika / Olive, Kenneth P

    Nature

    2024  

    Abstract: Broad-spectrum RAS inhibition holds the potential to benefit roughly a quarter of human cancer patients whose tumors are driven by RAS ... ...

    Abstract Broad-spectrum RAS inhibition holds the potential to benefit roughly a quarter of human cancer patients whose tumors are driven by RAS mutations
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-024-07379-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Horsenettle (Solanum carolinense) fruit bacterial communities are not variable across fine spatial scales

    Ariel R. Heminger / Lisa K. Belden / Jacob N. Barney / Brian D. Badgley / David C. Haak

    PeerJ, Vol 9, p e

    2021  Volume 12359

    Abstract: Fruit house microbial communities that are unique from the rest of the plant. While symbiotic microbial communities complete important functions for their hosts, the fruit microbiome is often understudied compared to other plant organs. Fruits are ... ...

    Abstract Fruit house microbial communities that are unique from the rest of the plant. While symbiotic microbial communities complete important functions for their hosts, the fruit microbiome is often understudied compared to other plant organs. Fruits are reproductive tissues that house, protect, and facilitate the dispersal of seeds, and thus they are directly tied to plant fitness. Fruit microbial communities may, therefore, also impact plant fitness. In this study, we assessed how bacterial communities associated with fruit of Solanum carolinense, a native herbaceous perennial weed, vary at fine spatial scales (<0.5 km). A majority of the studies conducted on plant microbial communities have been done at large spatial scales and have observed microbial community variation across these large spatial scales. However, both the environment and pollinators play a role in shaping plant microbial communities and likely have impacts on the plant microbiome at fine scales. We collected fruit samples from eight sampling locations, ranging from 2 to 450 m apart, and assessed the fruit bacterial communities using 16S rRNA gene amplicon sequencing. Overall, we found no differences in observed richness or microbial community composition among sampling locations. Bacterial community structure of fruits collected near one another were not more different than those that were farther apart at the scales we examined. These fine spatial scales are important to obligate out-crossing plant species such as S. carolinense because they are ecologically relevant to pollinators. Thus, our results could imply that pollinators serve to homogenize fruit bacterial communities across these smaller scales.
    Keywords Solanum carolinense ; Bacteria ; Microbiome ; Fruit microbiome ; Spatial distance ; Medicine ; R ; Biology (General) ; QH301-705.5
    Subject code 580
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher PeerJ Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Coupled influence of tectonics, climate, and surface processes on landscape evolution in southwestern North America.

    Bahadori, Alireza / Holt, William E / Feng, Ran / Austermann, Jacqueline / Loughney, Katharine M / Salles, Tristan / Moresi, Louis / Beucher, Romain / Lu, Neng / Flesch, Lucy M / Calvelage, Christopher M / Rasbury, E Troy / Davis, Daniel M / Potochnik, Andre R / Ward, W Bruce / Hatton, Kevin / Haq, Saad S B / Smiley, Tara M / Wooton, Kathleen M /
    Badgley, Catherine

    Nature communications

    2022  Volume 13, Issue 1, Page(s) 4437

    Abstract: The Cenozoic landscape evolution in southwestern North America is ascribed to crustal isostasy, dynamic topography, or lithosphere tectonics, but their relative contributions remain controversial. Here we reconstruct landscape history since the late ... ...

    Abstract The Cenozoic landscape evolution in southwestern North America is ascribed to crustal isostasy, dynamic topography, or lithosphere tectonics, but their relative contributions remain controversial. Here we reconstruct landscape history since the late Eocene by investigating the interplay between mantle convection, lithosphere dynamics, climate, and surface processes using fully coupled four-dimensional numerical models. Our quantified depth-dependent strain rate and stress history within the lithosphere, under the influence of gravitational collapse and sub-lithospheric mantle flow, show that high gravitational potential energy of a mountain chain relative to a lower Colorado Plateau can explain extension directions and stress magnitudes in the belt of metamorphic core complexes during topographic collapse. Profound lithospheric weakening through heating and partial melting, following slab rollback, promoted this extensional collapse. Landscape evolution guided northeast drainage onto the Colorado Plateau during the late Eocene-late Oligocene, south-southwest drainage reversal during the late Oligocene-middle Miocene, and southwest drainage following the late Miocene.
    Language English
    Publishing date 2022-08-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-022-31903-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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