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  1. Book: Non-fibrillar amyloidogenic protein assemblies

    Rahimi, Farid / Bitan, Gal

    common cytotoxins underlying degenerative diseases

    2012  

    Author's details Farid Rahimi ; Gal Bitan ed
    Language English
    Size VIII, 565 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017128625
    ISBN 978-94-007-2773-1 ; 94-007-2773-9 ; 9789400727748 ; 9400727747
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Alzheimer Disease: Controversies in Basic Science Research, Different Theories, and Reasons for Failed Trials.

    Rahimi, Farid

    Biomedicines

    2021  Volume 9, Issue 3

    Abstract: Dementia comprises a collection of cognitive and sensory symptoms, including memory loss, communication difficulties, difficulty in planning and problem solving, disorientation and confusion, compromised olfaction, loss of visual perception, agnosia; and ...

    Abstract Dementia comprises a collection of cognitive and sensory symptoms, including memory loss, communication difficulties, difficulty in planning and problem solving, disorientation and confusion, compromised olfaction, loss of visual perception, agnosia; and psychological symptoms, including personality and behavioral changes, depression, anxiety, hallucination, mood swings, agitation, and apathy [...].
    Language English
    Publishing date 2021-03-05
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines9030254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Alzheimer Disease

    Farid Rahimi

    Biomedicines, Vol 9, Iss 3, p

    Controversies in Basic Science Research, Different Theories, and Reasons for Failed Trials

    2021  Volume 254

    Abstract: Dementia comprises a collection of cognitive and sensory symptoms, including memory loss, communication difficulties, difficulty in planning and problem solving, disorientation and confusion, compromised olfaction, loss of visual perception, agnosia; and ...

    Abstract Dementia comprises a collection of cognitive and sensory symptoms, including memory loss, communication difficulties, difficulty in planning and problem solving, disorientation and confusion, compromised olfaction, loss of visual perception, agnosia; and psychological symptoms, including personality and behavioral changes, depression, anxiety, hallucination, mood swings, agitation, and apathy [.]
    Keywords n/a ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: ChatGPT and Corporations of Mega-journals Jeopardize the Norms That Underpin Academic Publishing.

    Rahimi, Farid / Talebi Bezmin Abadi, Amin

    Archives of Iranian medicine

    2024  Volume 27, Issue 2, Page(s) 110–112

    Abstract: Those who participate in and contribute to academic publishing are affected by its evolution. Funding bodies, academic institutions, researchers and peer-reviewers, junior scholars, freelance language editors, language-editing services, and journal ... ...

    Abstract Those who participate in and contribute to academic publishing are affected by its evolution. Funding bodies, academic institutions, researchers and peer-reviewers, junior scholars, freelance language editors, language-editing services, and journal editors are to enforce and uphold the ethical norms on which academic publishing is founded. Deviating from such norms will challenge and threaten the scholarly reputation, academic careers, and institutional standing; reduce the publishers' true impacts; squander public funding; and erode the public trust to the academic enterprise. Rigorous review is paramount because peer-review norms guarantee that scientific findings are scrutinized before being publicized. Volunteer peer-reviewers and guest journal editors devote an immense amount of unremunerated time to reviewing papers, voluntarily serving the scientific community, and benefiting the publishers. Some mega-journals are motivated to mass-produce publications and attract the funded projects instead of maintaining the scientific rigor. The rapid development of mega-journals may diminish some traditional journals by outcompeting their impacts. Artificial intelligence (AI) tools/algorithms such as ChatGPT may be misused to contribute to the mass-production of publications which may have not been rigorously revised or peer-reviewed. Maintaining norms that guarantee scientific rigor and academic integrity enable the academic community to overcome the new challenges such as mega-journals and AI tools.
    MeSH term(s) Humans ; Artificial Intelligence ; Periodicals as Topic ; Schools ; Algorithms ; Publishing
    Language English
    Publishing date 2024-02-01
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2204979-4
    ISSN 1735-3947 ; 1029-2977
    ISSN (online) 1735-3947
    ISSN 1029-2977
    DOI 10.34172/aim.2024.17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: 'The end' - or is it? Emergence of SARS-CoV-2 EG.5 and BA.2.86 subvariants.

    Rahimi, Farid / Darvishi, Mohammad / Bezmin Abadi, Amin Talebi

    Future virology

    2023  

    Language English
    Publishing date 2023-09-19
    Publishing country England
    Document type Editorial
    ZDB-ID 2254606-6
    ISSN 1746-0808 ; 1746-0794
    ISSN (online) 1746-0808
    ISSN 1746-0794
    DOI 10.2217/fvl-2023-0150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Emergence of the Omicron SARS-CoV-2 subvariants during the COVID-19 pandemic.

    Rahimi, Farid / Abadi, Amin Talebi Bezmin

    International journal of surgery (London, England)

    2022  Volume 108, Page(s) 106994

    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19/epidemiology ; Pandemics
    Language English
    Publishing date 2022-11-11
    Publishing country England
    Document type Letter
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2022.106994
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Corrigendum to 'Case-finding: Fast, Available, and Efficient Font-line Diagnostics for SARS-CoV-2'[Arch. Med. Res. 51(5) (2020) 453-454/ARCMED 2020 432].

    Rahimi, Farid / Talebi Bezmin Abadi, Amin

    Archives of medical research

    2023  Volume 54, Issue 5, Page(s) 102836

    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1156844-6
    ISSN 1873-5487 ; 0188-4409 ; 0188-0128
    ISSN (online) 1873-5487
    ISSN 0188-4409 ; 0188-0128
    DOI 10.1016/j.arcmed.2023.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Aptamers Selected for Recognizing Amyloid β-Protein-A Case for Cautious Optimism.

    Rahimi, Farid

    International journal of molecular sciences

    2018  Volume 19, Issue 3

    Abstract: ... However, application of aptamers to the field of amyloid β-protein (Aβ) has been limited so far. Aβ is an intrinsically ... Accumulated scientific evidence thus far highlights undesirable or nonspecific interactions between selected ...

    Abstract Aptamers are versatile oligonucleotide ligands used for molecular recognition of diverse targets. However, application of aptamers to the field of amyloid β-protein (Aβ) has been limited so far. Aβ is an intrinsically disordered protein that exists in a dynamic conformational equilibrium, presenting time-dependent ensembles of short-lived, metastable structures and assemblies that have been generally difficult to isolate and characterize. Moreover, despite understanding of potential physiological roles of Aβ, this peptide has been linked to the pathogenesis of Alzheimer disease, and its pathogenic roles remain controversial. Accumulated scientific evidence thus far highlights undesirable or nonspecific interactions between selected aptamers and different Aβ assemblies likely due to the metastable nature of Aβ or inherent affinity of RNA oligonucleotides to β-sheet-rich fibrillar structures of amyloidogenic proteins. Accordingly, lessons drawn from Aβ-aptamer studies emphasize that purity and uniformity of the protein target and rigorous characterization of aptamers' specificity are important for realizing and garnering the full potential of aptamers selected for recognizing Aβ or other intrinsically disordered proteins. This review summarizes studies of aptamers selected for recognizing different Aβ assemblies and highlights controversies, difficulties, and limitations of such studies.
    MeSH term(s) Alzheimer Disease/drug therapy ; Alzheimer Disease/etiology ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/metabolism ; Aptamers, Nucleotide/genetics ; Aptamers, Nucleotide/metabolism ; Drug Discovery ; Humans ; Ligands ; Protein Aggregates ; Protein Aggregation, Pathological ; Protein Binding ; SELEX Aptamer Technique
    Chemical Substances Amyloid beta-Peptides ; Aptamers, Nucleotide ; Ligands ; Protein Aggregates
    Language English
    Publishing date 2018-02-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms19030668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Omicron: A highly transmissible SARS-CoV-2 variant.

    Rahimi, Farid / Talebi Bezmin Abadi, Amin

    Gene reports

    2022  Volume 27, Page(s) 101549

    Language English
    Publishing date 2022-02-10
    Publishing country United States
    Document type Journal Article
    ISSN 2452-0144
    ISSN 2452-0144
    DOI 10.1016/j.genrep.2022.101549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Redox reactions in vitrified-warmed ovary.

    Rahimi, Atefe / Shahriari, Ali / Barati, Farid

    F&S science

    2023  Volume 5, Issue 1, Page(s) 39–42

    Abstract: Backgrounds: Ovary vitrification is a way for the preservation of fertility in women undergoing chemotherapy and for protecting the valuable or the endangered species. However, cryopreservation of complex tissues, which are composed of different cells ... ...

    Abstract Backgrounds: Ovary vitrification is a way for the preservation of fertility in women undergoing chemotherapy and for protecting the valuable or the endangered species. However, cryopreservation of complex tissues, which are composed of different cells and materials, encountered various challenges including oxidative stress damage.
    Objectives: This study aimed to evaluate some oxidative stress indices in the vitrified bovine ovaries.
    Methods: The pieces of the bovine ovarian cortex (1 × 1 × 1 mm
    Results: Total antioxidant capacity had a 45% decrease after vitrification (P<.0001). This reduction was associated with a 4 times increase in malondialdehyde (P=.0002) and a 53% decrease in superoxide dismutase (P=.0081). The levels of protein carbonyl in vitrified-warmed ovaries were less than in fresh ovaries (P=.0325). Regression analysis showed that the components of oxidative stress indices in vitrified tissues are different from those of fresh tissues.
    Conclusion: An extensive alteration was seen in oxidant/antioxidant balance during vitrification.
    MeSH term(s) Animals ; Female ; Cattle ; Humans ; Ovary ; Antioxidants ; Cryopreservation/veterinary ; Oxidation-Reduction ; Sucrose
    Chemical Substances Antioxidants ; Sucrose (57-50-1)
    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Journal Article
    ISSN 2666-335X
    ISSN (online) 2666-335X
    DOI 10.1016/j.xfss.2023.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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