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  1. Article ; Online: Environmental trade-offs and externalities of electrochemical-based batteries: Quantitative analysis between lithium-ion and vanadium redox flow units

    Tsai, Wen-Shuo / Huang, Chihchi / Huang, Chien-Chung / Yang, Chang-Chung / Lee, Mengshan

    Journal of Environmental Management. 2023 Jan., v. 326 p.116807-

    2023  

    Abstract: This study aims to increase the scientific knowledge of the environmental impacts and externalities of two promising electrochemical-based techniques for large-scale stationary energy storage: lithium nickel cobalt manganese (NCM) and vanadium redox flow ...

    Abstract This study aims to increase the scientific knowledge of the environmental impacts and externalities of two promising electrochemical-based techniques for large-scale stationary energy storage: lithium nickel cobalt manganese (NCM) and vanadium redox flow (VRF) batteries. The global warming potential (GWP) and cumulative energy demand (CED) for NCM and VRF batteries are 28 kg CO₂eq and 410 MJ and 186 kg CO₂eq and 3080 MJ, respectively, for the provision of 1 MWh of electricity. While the trend of the environmental externality results is proportional to the environmental impact results, the environmental costs from GWP and terrestrial ecotoxicity impacts contribute the largest share of the total environmental costs for both batteries. Overall, NCM batteries have favorable environmental performance in terms of their impact values and externalities but still show relatively higher contributions in human toxicity and ozone layer depletion impacts, based on their high resource uses. The VRF batteries, on the other hand, report higher impacts in abiotic depletion, GWP and terrestrial ecotoxicity, mainly due to their great mass of the electrolyte. Our results highlight the importance of substituting the active metals with low-impact metals or carefully considering the origin of key materials while also taking advantage of the properties of the battery to carefully assess possible advancements in battery design. The environmental externality results also provide essential information for the future development of battery industries for stationary applications with energy and environmental benefits.
    Keywords batteries ; cobalt ; ecotoxicology ; electricity ; electrolytes ; energy ; environmental impact ; environmental performance ; humans ; lithium ; manganese ; nickel ; ozonosphere ; quantitative analysis ; toxicity ; vanadium ; Life cycle assessment ; Stationary energy storage ; Environmental impacts ; Environmental cost
    Language English
    Dates of publication 2023-01
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2022.116807
    Database NAL-Catalogue (AGRICOLA)

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  2. Book: Ji wei ju jin wen shuo

    Yang, Shuda

    zeng ding ben

    (Kao gu xue zhuan kan : jia zhong ; di 1 hao ; 考古學專刊 : 甲種 ; 第1號)

    1959  

    Title variant Ji-wei-ju Jin-wen shuo ; Ji-wei-ju Jin-wen-shuo
    Institution Zhongguo kexueyuan kaogu yanjiusuo
    Author's details Yang shu da zhu; zhong guo ke xue yuan kao gu yan jiu suo bian ji
    Series title Kao gu xue zhuan kan : jia zhong ; di 1 hao
    考古學專刊 : 甲種 ; 第1號
    Keywords Inscriptions, Chinese
    Language Chinese
    Size 20, 299, 9 S., 26 cm
    Edition Di 2 ban
    Publisher Ke xue chu ban she
    Publishing place Bei jing
    Document type Book
    Note In chines. Schr. ; Bibliography: p. 297-299
    Database Former special subject collection: coastal and deep sea fishing

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  3. Article ; Online: Environmental trade-offs and externalities of electrochemical-based batteries: Quantitative analysis between lithium-ion and vanadium redox flow units.

    Tsai, Wen-Shuo / Huang, Chihchi / Huang, Chien-Chung / Yang, Chang-Chung / Lee, Mengshan

    Journal of environmental management

    2022  Volume 326, Issue Pt B, Page(s) 116807

    Abstract: This study aims to increase the scientific knowledge of the environmental impacts and externalities of two promising electrochemical-based techniques for large-scale stationary energy storage: lithium nickel cobalt manganese (NCM) and vanadium redox flow ...

    Abstract This study aims to increase the scientific knowledge of the environmental impacts and externalities of two promising electrochemical-based techniques for large-scale stationary energy storage: lithium nickel cobalt manganese (NCM) and vanadium redox flow (VRF) batteries. The global warming potential (GWP) and cumulative energy demand (CED) for NCM and VRF batteries are 28 kg CO
    Language English
    Publishing date 2022-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2022.116807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Copper-Nitrogen-Coordinated Carbon Dots: Transformable Phototheranostics from Precise PTT/PDT to Post-Treatment Imaging-Guided PDT for Residual Tumor Cells.

    Zhang, Lizhen / Yang, Aijia / Ruan, Changping / Jiang, Bang-Ping / Guo, Xiaolu / Liang, Hong / Kuo, Wen-Shuo / Shen, Xing-Can

    ACS applied materials & interfaces

    2023  Volume 15, Issue 2, Page(s) 3253–3265

    Abstract: Phototheranostics has attracted considerable attention in the fields of cancer diagnosis and treatment. However, the complete eradication of solid tumors using traditional phototheranostics is difficult because of the limited depth and range of laser ... ...

    Abstract Phototheranostics has attracted considerable attention in the fields of cancer diagnosis and treatment. However, the complete eradication of solid tumors using traditional phototheranostics is difficult because of the limited depth and range of laser irradiation. New phototheranostics enabling precise phototherapy and post-treatment imaging-guided programmed therapy for residual tumors is urgently required. Accordingly, this study developed a novel transformable phototheranostics by assembling hyaluronic acid (HA) with copper-nitrogen-coordinated carbon dots (CDs). In this transformable nanoplatform, named copper-nitrogen-CDs@HA, the HA component enables the specific targeting of cluster determinant (CD) 44-overexpressing tumor cells. In the tumor cells, redox glutathione converts Cu(II) (cupric ions) into Cu(I) (cuprous ions), which confers the novel transformable functionality to phototheranostics. Both
    MeSH term(s) Humans ; Carbon/chemistry ; Carbon/pharmacology ; Cell Line, Tumor ; Copper/chemistry ; Copper/pharmacology ; Nanoparticles/therapeutic use ; Neoplasm, Residual/drug therapy ; Photochemotherapy/methods ; Phototherapy ; Nitrogen/chemistry ; Nitrogen/pharmacology
    Chemical Substances Carbon (7440-44-0) ; Copper (789U1901C5) ; Nitrogen (N762921K75)
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.2c17525
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Copper-Nitrogen-Coordinated Carbon Dots: Transformable Phototheranostics from Precise PTT/PDT to Post-Treatment Imaging-Guided PDT for Residual Tumor Cells

    Zhang, Lizhen / Yang, Aijia / Ruan, Changping / Jiang, Bang-Ping / Guo, Xiaolu / Liang, Hong / Kuo, Wen-Shuo / Shen, Xing-Can

    ACS Applied Materials & Interfaces. 2023 Jan. 04, v. 15, no. 2 p.3253-3265

    2023  

    Abstract: Phototheranostics has attracted considerable attention in the fields of cancer diagnosis and treatment. However, the complete eradication of solid tumors using traditional phototheranostics is difficult because of the limited depth and range of laser ... ...

    Abstract Phototheranostics has attracted considerable attention in the fields of cancer diagnosis and treatment. However, the complete eradication of solid tumors using traditional phototheranostics is difficult because of the limited depth and range of laser irradiation. New phototheranostics enabling precise phototherapy and post-treatment imaging-guided programmed therapy for residual tumors is urgently required. Accordingly, this study developed a novel transformable phototheranostics by assembling hyaluronic acid (HA) with copper-nitrogen-coordinated carbon dots (CDs). In this transformable nanoplatform, named copper-nitrogen-CDs@HA, the HA component enables the specific targeting of cluster determinant (CD) 44-overexpressing tumor cells. In the tumor cells, redox glutathione converts Cu­(II) (cupric ions) into Cu­(I) (cuprous ions), which confers the novel transformable functionality to phototheranostics. Both in vitro and in vivo results reveal that the near-infrared-light-photoactivated Cuᴵᴵ-N-CDs@HA could target CD44-overexpressing tumor cells for precise synergistic photothermal therapy and photodynamic therapy. This study is the first to observe that Cuᴵᴵ-N-CDs@HA could escape from lysosomes and be transformed in situ into Cuᴵ-N-CDs@HA in tumor cells, with the d⁹ electronic configuration of Cu­(II) changing to the d¹⁰ electronic configuration of Cu­(I), which turns on their fluorescence and turns off their photothermal properties. This transformable phototheranostics could be used for post-treatment imaging-guided photodynamic therapy on residual tumor cells. Thus, the rationally designed copper-nitrogen-coordinated CDs offer a simple in situ transformation strategy for using multiple-stimulus-responsive precise phototheranostics in post-treatment monitoring of residual tumor cells and imaging-guided programmed therapy.
    Keywords carbon ; fluorescence ; glutathione ; hyaluronic acid ; irradiation ; lysosomes ; neoplasms ; photochemotherapy ; photothermotherapy ; copper-nitrogen-coordinated carbon dot ; lysosome escape ; transformable phototheranostics ; post-treatment ; imaging-guided phototherapy
    Language English
    Dates of publication 2023-0104
    Size p. 3253-3265.
    Publishing place American Chemical Society
    Document type Article ; Online
    ISSN 1944-8252
    DOI 10.1021/acsami.2c17525
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Objective performance of emergency medical technicians in the use of mechanical cardiopulmonary resuscitation compared with subjective self-evaluation: a cross-sectional, simulation-based study.

    Yang, Wen-Shuo / Yen, Ping / Wang, Yao-Cheng / Chien, Yu-Chun / Chie, Wei-Chu / Ma, Matthew Huei-Ming / Chiang, Wen-Chu

    BMJ open

    2022  Volume 12, Issue 6, Page(s) e062908

    Abstract: Objective: To evaluate the subjective and objective resuscitation performance of emergency medical technicians (EMTs) using mechanical cardiopulmonary resuscitation (MCPR) devices.: Design and setting: This was a cross-sectional simulation-based ... ...

    Abstract Objective: To evaluate the subjective and objective resuscitation performance of emergency medical technicians (EMTs) using mechanical cardiopulmonary resuscitation (MCPR) devices.
    Design and setting: This was a cross-sectional simulation-based study where participants installed the MCPR device on a training manikin.
    Participants: We assessed EMT-Intermediates (EMT-Is) and EMT-Paramedics (EMT-Ps) of the Emergency Medical Services (Ambulance) Division of the Taipei City Fire Department.
    Primary and secondary outcome measures: The primary outcome was the gap between self-perceived (subjective) and actual (objective) no-flow time during resuscitation, which we hypothesised as statistically insignificant. The secondary outcome was the association between resuscitation performance and personal attributes like knowledge, attitude and self-confidence.
    Results: Among 210 participants between 21 and 45 years old, only six were female. There were 144 EMT-Is and 66 EMT-Ps. During a simulated resuscitation lasting between four and a half and 5 min, EMTs had longer actual no-flow time compared with self-perceived no-flow time (subjective, 38 s; objective, 57.5 s; p value<0.001). This discrepancy could cause a 6.5% drop of the chest compression fraction in a resuscitation period of 5 min. Among the EMT personal factors, self-confidence was negatively associated with objective MCPR deployment performance (adjusted OR (aOR) 0.66, 95% CI 0.45 to 0.97, p=0.033) and objective teamwork performance (aOR 0.57, 95% CI 0.34 to 0.97, p=0.037) for EMT-Ps, whereas knowledge was positively associated with objective MCPR deployment performance (aOR 2.15, 95% CI 1.31 to 3.52, p=0.002) and objective teamwork performance (aOR 1.77, 95% CI 1.02 to 3.08, p=0.043) for EMT-Is. Moreover, regarding the self-evaluation of no-flow time, both self-satisfaction and self-abasement were associated with objectively poor teamwork performance.
    Conclusions: EMTs' subjective and objective performance was inconsistent during the MCPR simulation. Self-confidence and knowledge were personal factors associated with MCPR deployment and teamwork performance. Both self-satisfaction and self-abasement were detrimental to teamwork during resuscitation.
    MeSH term(s) Adult ; Cardiopulmonary Resuscitation ; Cross-Sectional Studies ; Emergency Medical Services ; Emergency Medical Technicians/education ; Female ; Humans ; Male ; Middle Aged ; Self-Assessment ; Young Adult
    Language English
    Publishing date 2022-06-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-062908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sacrificial template synthesis of hollow sulfonate group functionalized microporous organic network for efficient solid phase extraction of sulfonamide antibiotics from milk and honey samples.

    Gao, Shuo-Wen / Chen, Li-Hua / Cui, Yuan-Yuan / Yang, Cheng-Xiong

    Journal of chromatography. A

    2024  Volume 1721, Page(s) 464844

    Abstract: The highly conjugated and hydrophobic characteristics of microporous organic networks (MONs) have largely impeded their broad applications in sample pretreatment especially for the polar or ionic analytes. In this work, a novel uniform hollow shaped ... ...

    Abstract The highly conjugated and hydrophobic characteristics of microporous organic networks (MONs) have largely impeded their broad applications in sample pretreatment especially for the polar or ionic analytes. In this work, a novel uniform hollow shaped sulfonate group functionalized MON (H-MON-SO
    MeSH term(s) Anti-Bacterial Agents/analysis ; Honey/analysis ; Solid Phase Extraction/methods ; Chromatography, High Pressure Liquid/methods ; Sulfanilamide/analysis ; Water/chemistry ; Sulfonamides/analysis
    Chemical Substances Anti-Bacterial Agents ; Sulfanilamide (21240MF57M) ; Water (059QF0KO0R) ; Sulfonamides
    Language English
    Publishing date 2024-03-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1171488-8
    ISSN 1873-3778 ; 0021-9673
    ISSN (online) 1873-3778
    ISSN 0021-9673
    DOI 10.1016/j.chroma.2024.464844
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Objective performance of emergency medical technicians in the use of mechanical cardiopulmonary resuscitation compared with subjective self-evaluation

    Wen-Chu Chiang / Matthew Huei-Ming Ma / Yu-Chun Chien / Yao-Cheng Wang / Wen-Shuo Yang / Ping Yen / Wei-Chu Chie

    BMJ Open, Vol 12, Iss

    a cross-sectional, simulation-based study

    2022  Volume 6

    Keywords Medicine ; R
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Fibroblast growth factor 15, induced by elevated bile acids, mediates the improvement of hepatic glucose metabolism after sleeve gastrectomy.

    Wei, Meng / Cao, Wei-Bo / Zhao, Ru-Dong / Sun, Dan-Ping / Liang, Yi-Ze / Huang, Ya-Di / Cheng, Ze-Wei / Ouyang, Jun / Yang, Wen-Shuo / Yu, Wen-Bin

    World journal of gastroenterology

    2023  Volume 29, Issue 21, Page(s) 3280–3291

    Abstract: Background: Fibroblast growth factor (FGF) 15/19, which is expressed in and secreted from the distal ileum, can regulate hepatic glucose metabolism in an endocrine manner. The levels of both bile acids (BAs) and FGF15/19 are elevated after bariatric ... ...

    Abstract Background: Fibroblast growth factor (FGF) 15/19, which is expressed in and secreted from the distal ileum, can regulate hepatic glucose metabolism in an endocrine manner. The levels of both bile acids (BAs) and FGF15/19 are elevated after bariatric surgery. However, it is unclear whether the increase in FGF15/19 is induced by BAs. Moreover, it remains to be understood whether FGF15/19 elevations contribute to improvements in hepatic glucose metabolism after bariatric surgery.
    Aim: To investigate the mechanism of improvement of hepatic glucose metabolism by elevated BAs after sleeve gastrectomy (SG).
    Methods: By calculating and comparing the changes of body weight after SG with SHAM group, we examined the weight-loss effect of SG. The oral glucose tolerance test (OGTT) test and area under the curve of OGTT curves were used to assess the anti-diabetic effects of SG. By detecting the glycogen content, expression and activity of glycogen synthase as well as the glucose-6-phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (Pepck), we evaluated the hepatic glycogen content and gluconeogenesis activity. We examined the levels of total BA (TBA) together with the farnesoid X receptor (FXR)-agonistic BA subspecies in systemic serum and portal vein at week 12 post-surgery. Then the histological expression of ileal FXR and FGF15 and hepatic FGF receptor 4 (FGFR4) with its corresponding signal pathways involved in glucose metabolism were detected.
    Results: After surgery, food intake and body weight gain of SG group was decreased compare with the SHAM group. The hepatic glycogen content and glycogen synthase activity was significantly stimulated after SG, while the expression of the key enzyme for hepatic gluconeogenesis: G6Pase and Pepck, were depressed. TBA levels in serum and portal vein were both elevated after SG, the FXR-agonistic BA subspecies: Chenodeoxycholic acid (CDCA), lithocholic acid (LCA) in serum and CDCA, DCA, LCA in portal vein were all higher in SG group than that in SHAM group. Consequently, the ileal expression of FXR and FGF15 were also advanced in SG group. Moreover, the hepatic expression of FGFR4 was stimulated in SG-operated rats. As a result, the activity of its corresponding pathway for glycogen synthesis: FGFR4-Ras-extracellular signal regulated kinase pathway was stimulated, while the corresponding pathway for hepatic gluconeogenesis: FGFR4- cAMP regulatory element-binding protein- peroxisome proliferator-activated receptor γ coactivator-1α pathway was suppressed.
    Conclusion: Elevated BAs after SG induced FGF15 expression in distal ileum by activating their receptor FXR. Furthermore, the promoted FGF15 partly mediated the improving effects on hepatic glucose metabolism of SG.
    MeSH term(s) Rats ; Animals ; Glucose/metabolism ; Fibroblast Growth Factors/metabolism ; Glycogen Synthase/metabolism ; Liver Glycogen/metabolism ; Liver/metabolism ; Body Weight ; Bile Acids and Salts/metabolism ; Gastrectomy
    Chemical Substances Glucose (IY9XDZ35W2) ; Fibroblast Growth Factors (62031-54-3) ; Glycogen Synthase (EC 2.4.1.11) ; Liver Glycogen ; Bile Acids and Salts
    Language English
    Publishing date 2023-06-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v29.i21.3280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply to: Taipei Azalea: Another example of "MacGyver bias" during COVID-19 pandemic?

    Yang, Wen-Shuo / Lee, Bin-Chou / Chiang, Wen-Chu / Chien, Yu-Chun / Chen, Shey-Ying / Ma, Matthew Huei-Ming / Hou, Sheng-Wen

    Resuscitation

    2020  Volume 154, Page(s) 125–126

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-11
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2020.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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