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Article ; Online: Single anastomosis duodenal switch versus Roux-en-Y gastric bypass in patients with BMI ≥ 50 kg/m

Hage, Karl / Teixeira, Andre F / Surve, Amit / Lind, Romulo / Jawad, Muhammad A / Ghanem, Muhammad / Abi Mosleh, Kamal / Kendrick, Michael L / Cottam, Daniel / Ghanem, Omar M

Surgical endoscopy

2024

Abstract: ... outcomes of SADI-S in patients with BMI ≥ 50 kg/m: Methods: We performed a multicenter ... retrospective study of patients with a BMI ≥ 50 kg/m: Results: A total of 968 patients (343 RYGB and 625 SADI-S; 68 ... 3% female, age 42.9 ± 12.1 years; BMI 57.3 ± 6.7 kg/m: Conclusions: In our cohort, SADI-S was ...

Abstract	Background: Roux-en-Y gastric bypass (RYGB) has consistently demonstrated excellent weight loss and comorbidity resolution. However, outcomes vary based on patient's BMI. Single anastomosis duodeno-ileostomy with sleeve (SADI-S) is a novel procedure with promising short-term results. The long-term outcomes of SADI-S in patients with BMI ≥ 50 kg/m Methods: We performed a multicenter retrospective study of patients with a BMI ≥ 50 kg/m Results: A total of 968 patients (343 RYGB and 625 SADI-S; 68.3% female, age 42.9 ± 12.1 years; BMI 57.3 ± 6.7 kg/m Conclusions: In our cohort, SADI-S was associated with higher and sustained weight-loss results compared to RYGB. Comorbidity resolution was also higher after SADI-S. Both procedures demonstrate a similar safety profile. Further studies are required to validate the long-term safety of SADI-S compared to other bariatric procedures.
Language	English
Publishing date	2024-03-20
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639039-0
ISSN	1432-2218 ; 0930-2794
ISSN (online)	1432-2218
ISSN	0930-2794
DOI	10.1007/s00464-024-10765-3
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Article ; Online: Comparative multicenter analysis of sleeve gastrectomy, gastric bypass, and duodenal switch in patients with BMI ≥70kg/m

Abi Mosleh, Kamal / Lind, Romulo / Salame, Marita / Jawad, Muhammad A / Ghanem, Muhammad / Hage, Karl / Abu Dayyeh, Barham K / Kendrick, Michael / Teixeira, Andre F / Ghanem, Omar M

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

2023 Volume 20, Issue 4, Page(s) 399–405

Abstract: Patients undergoing metabolic and bariatric surgery (MBS) with body mass index (BMI) ≥ 70 kg/m ...

Abstract	Patients undergoing metabolic and bariatric surgery (MBS) with body mass index (BMI) ≥ 70 kg/m
MeSH term(s)	Humans ; Gastric Bypass/methods ; Obesity, Morbid/surgery ; Body Mass Index ; Follow-Up Studies ; Retrospective Studies ; Gastrectomy/methods ; Treatment Outcome ; Multicenter Studies as Topic
Language	English
Publishing date	2023-11-30
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2274243-8
ISSN	1878-7533 ; 1550-7289
ISSN (online)	1878-7533
ISSN	1550-7289
DOI	10.1016/j.soard.2023.11.011
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Article ; Online: Emergence of multidrug-resistant ST11 blaKPC-2 producing Klebsiella pneumoniae coharboring blaCTX-M and blaSHV in Pakistan.

Jamal Gondal, Aamir / Saleem, Sidrah / Choudhry, Nakhshab / Jawad Ahmad, Fridoon / Bukhari, Hina / Yasmin, Nighat / Jahan, Shah

Journal of infection in developing countries

2023 Volume 17, Issue 2, Page(s) 210–217

Abstract: ... p = 0.04). blaKPC-2 producing K. pneumoniae coharboring blaCTX-M/blaSHV (66.7%) and blaCTX-M (33.3 ... exhibited sequence type (ST) 258 (n = 4) and ST11 (n = 2) sequence types with IncFII, IncN, IncFIIA, IncL/M ... 2 producing K. pneumoniae ST11 coharboring blaCTX-M and blaSHV in Pakistan. ...

Abstract	Introduction: Carbapenemases are primarily responsible for the intensified spread of multidrug-resistant (MDR) K. pneumoniae by virtue of antibiotics overuse. Therefore, frequent investigation of high-risk clones especially from developing world is crucial to curtail global spread. Methodology: In this observational study, 107 K. pneumoniae were retrieved and confirmed genotypically from April 2018 to March 2020 from tertiary care hospitals in Lahore, Pakistan. Carbapenemases and extended-spectrum β-lactamases were verified by Polymerase Chain Reaction and Sanger sequencing. Multilocus sequence typing and plasmid replicon typing were used to assign clonal lineages and plasmid replicons. Results: Among the K. pneumoniae, 72.9% (78/107) strains were carbapenem resistant (CR) with 65.4% (51/78) exhibiting carbapenemase producing phenotype. Among CR K. pneumoniae 38.5% (30/78) strains exhibited the following carbapenemase genotypes: blaNDM-1 (26.7%, 8/30), blaOXA-48 (26.7%, 8/30), blaKPC-2 (20.0%, 6/30), blaVIM (10.0%, 3/30), blaNDM-1/blaOXA-48 (10.0%, 3/30), blaOXA-48/blaVIM (3.3%, 1/30) and blaOXA-48/blaIMP (3.3%, 1/30). Tigecycline and polymyxin-B retained susceptible profile. β-lactam drugs showed intermediate to high resistance. The occurrence of CR K. pneumoniae infections was significantly associated with wound (39.7%, p = 0.0007), pus (38.5%, p = 0.009), general surgery (34.6%, p = 0.002) and intensive-care unit (26.9%, p = 0.04). blaKPC-2 producing K. pneumoniae coharboring blaCTX-M/blaSHV (66.7%) and blaCTX-M (33.3%) exhibited sequence type (ST) 258 (n = 4) and ST11 (n = 2) sequence types with IncFII, IncN, IncFIIA, IncL/M and IncFIIK plasmids. Conclusions: This is the first report describing the emergence of MDR blaKPC-2 producing K. pneumoniae ST11 coharboring blaCTX-M and blaSHV in Pakistan.
MeSH term(s)	Humans ; Klebsiella pneumoniae/genetics ; Pakistan ; Klebsiella Infections/drug therapy ; beta-Lactamases/genetics ; Anti-Bacterial Agents/therapeutic use ; Plasmids ; Carbapenems ; Multilocus Sequence Typing ; Microbial Sensitivity Tests
Chemical Substances	beta-Lactamases (EC 3.5.2.6) ; Anti-Bacterial Agents ; Carbapenems
Language	English
Publishing date	2023-02-28
Publishing country	Italy
Document type	Observational Study ; Journal Article
ZDB-ID	2394024-4
ISSN	1972-2680 ; 2036-6590
ISSN (online)	1972-2680
ISSN	2036-6590
DOI	10.3855/jidc.17041
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Article ; Online: Jassim M. Jawad Bochner curvature tensor of Almost Kahler manifold

Jassim Jawad

مجلة علوم ذي قار, Vol 2, Iss

2019 Volume 2

Abstract: In this paper we study the Bochner curvature tensor of almost Kahler manifold. We found the components of Bochner tensor of almost Kahler manifold in the adjoint G-structure space by using Kirichenko's tensors. It has been proved that an almost Kahler ... ...

Abstract	In this paper we study the Bochner curvature tensor of almost Kahler manifold. We found the components of Bochner tensor of almost Kahler manifold in the adjoint G-structure space by using Kirichenko's tensors. It has been proved that an almost Kahler manifold is a manifold of class if and only if it is Kahler.
Keywords	Physics ; QC1-999 ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Language	English
Publishing date	2019-05-01T00:00:00Z
Publisher	University of Thi-Qar
Document type	Article ; Online
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Article ; Online: Achievable Rate of NOMA-Based Cooperative Spectrum-Sharing CRN over Nakagami- m Channels

Sajid Hussain Alvi / Bakhtiar Ali / Jawad Mirza / Ali Khaqan / Muhammad Awais Javed / Jehad Ali / Niamat Hussain

Applied Sciences, Vol 12, Iss 12010, p

2022 Volume 12010

Abstract: ... issue. To evaluate the performance of the network over Nakagami- m channels, ergodic achievable rates ... of fading index m . Finally, we compare the results of the analytical expressions with simulated results ...

Abstract	Efficient data dissemination is a key challenge for IoT applications. In this paper, we present an ergodic achievable rate analysis of the non-orthogonal multiple access (NOMA)-based cooperative transmission scheme in spectrum-sharing cognitive radio networks (CRNs). The transmission scheme consists of two phases, where the NOMA transmission strategy is employed at the secondary transmitter (ST) in the second phase to serve the primary receiver (PR) and secondary receivers (SRs). This cooperative spectrum-sharing transmission is favourable when the ST-PR link is strong and the ST faces a spectrum scarcity issue. To evaluate the performance of the network over Nakagami- m channels, ergodic achievable rates at PR and SRs are derived in closed forms, which can be used for any integer or non-integer value of fading index m . Finally, we compare the results of the analytical expressions with simulated results for validation.
Keywords	non-orthogonal multiple access (NOMA) ; cognitive radio ; achievable rate ; Nakagami- m channels ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	003
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Public private partnership in in-service training of physicians: the millennium development goal 6-partnership for African clinical training (M-PACT) approach.

Oleribe, Obinna Ositadimma / Salako, Babatunde Lawal / Akpalu, Albert / Anteyi, Emmanuel / Ka, Mamadou Mourtalla / Deen, Gibrilla / Akande, Temilola / Abellona U, Mei Ran / Lemoine, Maud / McConnochie, Mairi / Foster, Matthew / Walker, Richard / Taylor-Robinson, Simon David / Jawad, Ali

The Pan African medical journal

2018 Volume 29, Page(s) 77

Abstract: ... Training (M-PACT) program was an innovative in-service training approach designed and implemented ... course 1.: Conclusion: M-PACT made a positive impact to quality and outcome of healthcare services ...

Abstract	Introduction: in-service training of healthcare workers is essential for improving healthcare services and outcome. Methods: The Millennium Development Goal (MDG) 6 Partnership for African Clinical Training (M-PACT) program was an innovative in-service training approach designed and implemented by the Royal College of Physicians (RCP) and West African College of Physicians (WACP) with funding from Eco Bank Foundation. The goal was to develop sustainable capacity to tackle MDG 6 targets in West Africa through better postgraduate medical education. Five training centres were establised: Nigeria (Abuja, Ibadan), Ghana (Accra), Senegal (Dakar) and Sierra Leone (Freetown) for training 681 physicians from across West Africa. A curriculum jointly designed by the RCP-WACP team was used to deliver biannual 5-day training courses over a 3-year period. Results: Of 602 trained in clinical medicine, 358 (59.5%) were males and 535 (88.9%) were from hosting countries. 472 (78.4%) of participants received travel bursaries to participate, while 318 (52.8%) were residents in Internal Medicine in the respective institutions. Accra had the highest number of participants (29.7%) followed by Ibadan, (28.7%), Dakar, (24.9%), Abuja, (11.0%) and Freetown, (5.6%). Pre-course clinical knowledge scores ranged from 35.1% in the Freetown Course to 63.8% in Accra Course 1; whereas post-course scores ranged from 50.5% in the Freetown course to 73.8% in Accra course 1. Conclusion: M-PACT made a positive impact to quality and outcome of healthcare services in the region and is a model for continued improvement for healthcare outcomes, e.g malaria, HIV and TB incidence and mortality in West Africa.
MeSH term(s)	Africa, Western ; Curriculum ; Delivery of Health Care/standards ; Education, Medical, Continuing/methods ; Educational Measurement ; Female ; Humans ; Inservice Training/methods ; Male ; Physicians/standards ; Public-Private Sector Partnerships ; Quality Improvement
Language	English
Publishing date	2018-01-25
Publishing country	Uganda
Document type	Journal Article ; Multicenter Study
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2018.29.77.14480
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Article: Oncostatin M in bronchoalveolar lavage correlates with the severity of sarcoidosis.

Guber, A / Jawad, A Q / Salomon, P / Mekori, Y A / Shitrit, D

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG

2013 Volume 30, Issue 3, Page(s) 194–200

Abstract: Background: Recent studies have shown that oncostatin M (OSM) might have a role in T cell ... for total mast cell count. The mouse anti-human Oncostatin M was applied and activated mast cells were ...

Abstract	Background: Recent studies have shown that oncostatin M (OSM) might have a role in T cell-mediated inflammatory processes in which mast cells are also involved. Patients with severe sarcoidosis might develop fibrotic changes in the lung. We assessed whether there was a correlation between mast cells expressing OSM in bronchoalveolar lavage (BAL) and the severity of sarcoidosis. Patients and methods: Twelve consecutive patients with new diagnosis of sarcoidosis were eligible for the study. All underwent complete lung function tests, angiotensin converting enzyme (ACE), and bronchoscopy that included BAL and biopsies. Cytospins of BAL were prepared. All samples were incubated with the primary antibody rabbit anti-human c-kit, CD117 and stained for total mast cell count. The mouse anti-human Oncostatin M was applied and activated mast cells were counted. Clinical sarcoidosis parameters including ACE and lung functions were correlated with mast cells in BAL, as well as with OSM positive mast cells. Results: FEV1 % was correlated with the percentage of activated mast cells, as well as with the percentage of OSM positive mast cells (r=0.61, p=0.033, 95% CI: 0.06-0.87; r=0.58, p=0.04, 95% CI: 0.015-0.86, respectively). FVC and FEV1/FVC correlated with activated mast cells (r=0.58, p=0.05; r=0.63, p=0.028, respectively). Conclusions: Direct correlation was found between clinical parameters including lung function tests (FEV1 and FVC) and OSM secretion from mast cells in patients with sarcoidosis. These findings suggest that mast cells and OSM have a role in sarcoidosis. Further studies to confirm these preliminary results are suggested.
MeSH term(s)	Animals ; Bronchoalveolar Lavage ; Bronchoalveolar Lavage Fluid ; Humans ; Lung ; Oncostatin M ; Sarcoidosis/immunology
Chemical Substances	Oncostatin M (106956-32-5)
Language	English
Publishing date	2013-11-25
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1339192-6
ISSN	1124-0490
ISSN	1124-0490
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Article ; Online: Outcomes of Roux-en-Y gastric bypass in the super obese: comparison of body mass index 50-60 kg/m(2) and≥60 kg/m(2) with the morbidly obese.

Moon, Rena C / Nelson, Lars / Teixeira, Andre F / Jawad, Muhammad A

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

2016 Volume 12, Issue 2, Page(s) 292–296

Abstract: ... limited, especially on patients with body mass index (BMI)≥60 kg/m(2).: Objectives: The aim ... by comparing patients with a BMI of 50-60 kg/m(2) and a BMI of≥60 kg/m(2) with patients with a BMI of 40-50 kg ... m(2).: Setting: Academic practice.: Methods: Between January 2004 and November 2013, a total ...

Abstract	Background: Reports on the outcomes of Roux-en-Y gastric bypass (RYGB) in super-obese patients are limited, especially on patients with body mass index (BMI)≥60 kg/m(2). Objectives: The aim of the present study was to evaluate and compare the tolerability and efficacy of RYGB in the super-obese by comparing patients with a BMI of 50-60 kg/m(2) and a BMI of≥60 kg/m(2) with patients with a BMI of 40-50 kg/m(2). Setting: Academic practice. Methods: Between January 2004 and November 2013, a total of 2717 patients underwent RYGB at our institution. Of these, 661 (24.3%) had a preoperative BMI of 50-60 kg/m(2) and 230 (8.5%) had a BMI≥60 kg/m(2). A retrospective review of outcomes and complications was performed, comparing these patients with 1555 patients with a BMI between 40-50 kg/m(2). Results: Fifty-two (3.3%) patients in the BMI 40-50 kg/m(2) group, 15 (2.3%) patients in the BMI 50-60 kg/m(2) group, and 3 (1.3%) patients in the BMI≥60 kg/m(2) had<30 days of follow-up. Readmission rates were 10.7%, 9.2%, and 11.7%, and reoperation rates were 7.3%, 5.0%, and 6.1%, in the BMI 40-50, 50-60, and≥60 kg/m(2) groups, respectively. No significant difference was found in readmission rate among the 3 groups, and reoperation rate was significantly lower in the BMI 50-60 kg/m(2) group. Mean percentage of excess BMI loss was 58.3%, 80.6%, 85.8%, 83.3%, and 80.9% in the BMI 40-50 kg/m(2) group; 44.9%, 65.0%, 70.1%, 72.1%, and 65.9% in the BMI 50-60 kg/m(2) group; and 38.5%, 57.4%, 62.2%, 62.8%, and 59.1% in the≥60 kg/m(2) group at 6, 12, 18, 24, and 36 months, respectively. The differences in excess BMI loss were statistically significant among all 3 groups at all follow-up time points. All groups experienced a significant decrease in their mean number of co-morbidities after the procedure. Conclusion: Readmission and reoperation rates were similar in the BMI 40-50, 50-60, and≥60 kg/m(2) groups. Super-obese and super-super-obese patients are not at greater risk for surgical complications compared with those with lower BMIs.
MeSH term(s)	Adolescent ; Adult ; Aged ; Body Mass Index ; Female ; Florida/epidemiology ; Gastric Bypass/methods ; Humans ; Laparoscopy/methods ; Male ; Middle Aged ; Morbidity/trends ; Obesity, Morbid/surgery ; Postoperative Complications/epidemiology ; Reoperation ; Retrospective Studies ; Treatment Outcome ; Weight Loss ; Young Adult
Language	English
Publishing date	2016-02
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	2274243-8
ISSN	1878-7533 ; 1550-7289
ISSN (online)	1878-7533
ISSN	1550-7289
DOI	10.1016/j.soard.2015.10.072
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Article ; Online: Web-based Context-Aware m-Learning Architecture

Rachid Benlamri / Jamal Zemerly / Jawad Berri / Eisa Basaeed

International Journal of Interactive Mobile Technologies (iJIM), Vol 1, Iss

2007 Volume 1

Abstract: ... hence facilitating immediate implementation. The paper ends with a real world scenario where m-Learning could be ...

Abstract	Context awareness is essential in mobile learning being a highly personalized environment with diverse capabilities. Major challenges of context awareness are to define the learning context, how to sense it, and how to react to changes. Our proposed system provides a general architecture that facilitates contextualization using current widely-used web standards. It provides a systematic approach to achieve contextualization defining major components and their functionalities without deepening into details. It uses web services to connect to resources making them reusable and distributable. In addition, all technologies and platforms proposed in our system are available under General Public License (GPL) hence facilitating immediate implementation. The paper ends with a real world scenario where m-Learning could be the only solution.
Keywords	Context-awareness ; educational technology ; m-Learning ; mobile aided learning ; ontology ; Electronic computers. Computer science ; QA75.5-76.95 ; Instruments and machines ; QA71-90 ; Mathematics ; QA1-939 ; Science ; Q ; DOAJ:Computer Science ; DOAJ:Technology and Engineering
Subject code	006
Language	English
Publishing date	2007-10-01T00:00:00Z
Publisher	Universität Kassel
Document type	Article ; Online
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Article ; Online: New sedation guidance in primary care.

Yeo, X / Jawad, M

British dental journal

2024 Volume 236, Issue 7, Page(s) 506–507

MeSH term(s)	Primary Health Care
Language	English
Publishing date	2024-04-12
Publishing country	England
Document type	Letter
ZDB-ID	218090-x
ISSN	1476-5373 ; 0007-0610
ISSN (online)	1476-5373
ISSN	0007-0610
DOI	10.1038/s41415-024-7305-z
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