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Article ; Online: Seeking solitude skills: Do memories of intrinsic goals enhance enjoyment of alone time?

Bradshaw, Emma L / Ferber, Kelly A / Ryan, Richard M

2024

Abstract: Objective: Further investigate the application of self-determination theory (SDT) to experiences of solitude by examining the effects of recalling intrinsic versus non-intrinsic memories.: Background: SDT research indicates that recalling memories ... ...

Abstract	Objective: Further investigate the application of self-determination theory (SDT) to experiences of solitude by examining the effects of recalling intrinsic versus non-intrinsic memories. Background: SDT research indicates that recalling memories associated with intrinsic goals (e.g., personal growth, relationships, altruism) enhances present moment wellness by satisfying basic psychological needs. Method: Two studies were conducted with American adults. Study 1 included 465 participants (age = 49.49 [SD = 19.01], 49.46% female) and Study 2 comprised 490 participants (age = 54.16 [SD = 18.89], 51.84% female). Both studies assessed the impact of recalling intrinsic versus non-intrinsic memories prior to a five-minute solitude session. Results: Study 1 found intrinsic memories were linked to more basic psychological need satisfaction than non-intrinsic memories, but both memory types resulted in similar wellness improvements. Contrary to expectations, Study 2 revealed extrinsic memories (e.g., wealth, fame, image) led to the highest basic psychological need satisfaction and least need frustration compared to intrinsic and neutral memories, with all memory conditions showing similar wellness gains. Conclusions: Solitude appears beneficial regardless of memory content. While different memories vary in need satisfying quality, this does not seem to impact the benefits of solitude. These findings suggest further exploration is needed before developing a "solitude skill set" for use during inevitable periods of solitude.
Language	English
Publishing date	2024-01-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	420745-2
ISSN	1467-6494 ; 0022-3506
ISSN (online)	1467-6494
ISSN	0022-3506
DOI	10.1111/jopy.12914
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Zs.A 1363: Show issues

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Article ; Online: Electrical Stimulation Use in Upper Extremity Peripheral Nerve Injuries.

Morrell, Nathan T / Dahlberg, Ryan K / Scott, Kelly L

The Journal of the American Academy of Orthopaedic Surgeons

2023 Volume 32, Issue 4, Page(s) 156–161

Abstract: Peripheral nerve injuries can be debilitating and often have a variable course of recovery. Electrical stimulation (ES) has been used as an intervention to attempt to overcome the limits of peripheral nerve surgery and improve patient outcomes after ... ...

Abstract	Peripheral nerve injuries can be debilitating and often have a variable course of recovery. Electrical stimulation (ES) has been used as an intervention to attempt to overcome the limits of peripheral nerve surgery and improve patient outcomes after peripheral nerve injury. Little has been written in the orthopaedic literature regarding the use of this technology. The purpose of this review was to provide a focused analysis of past and current literature surrounding the utilization of ES in the treatment of various upper extremity peripheral nerve pathologies including compression neuropathies and nerve transection. We aimed to provide clarity on the clinical benefits, appropriate timing for its employment, risks and limitations, and the need for future studies of ES.
MeSH term(s)	Humans ; Peripheral Nerve Injuries/therapy ; Upper Extremity/surgery ; Orthopedics ; Nerve Compression Syndromes ; Electric Stimulation ; Peripheral Nerves
Language	English
Publishing date	2023-12-14
Publishing country	United States
Document type	Review ; Journal Article
ZDB-ID	1200524-1
ISSN	1940-5480 ; 1067-151X
ISSN (online)	1940-5480
ISSN	1067-151X
DOI	10.5435/JAAOS-D-23-00437
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Zs.A 4048: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 274: Show issues

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Article ; Online: Physicians' Perspectives on Their Training for and Role Within Pennsylvania's Medical Cannabis Program.

Bui, Khanh / Worster, Brooke / Ryan, Jennie / Pant, Swechhya / Kelly, Erin L

Journal of the American Board of Family Medicine : JABFM

2023 Volume 36, Issue 4, Page(s) 670–681

Abstract: Background: Physicians' ability to guide their patients on the use of medical cannabis can vary widely and is often shaped by their training, experiences, and the regulations and policies of their state. The goal of this qualitative study is to ... ...

Abstract	Background: Physicians' ability to guide their patients on the use of medical cannabis can vary widely and is often shaped by their training, experiences, and the regulations and policies of their state. The goal of this qualitative study is to understand how prepared physicians are to certify and advise their patients to use medical cannabis. A secondary goal is to explore how physicians integrate certification into their clinical practices, and what factors shape their decisions and behaviors around certification. Method: Using semi-structured interviews with 24 physicians authorized to certify patients to use medical cannabis in Pennsylvania, a state with a medical access only program, we explored how physicians are trained and set up their practices. Interviews were analyzed using a blend of directed and conventional, and summative content analysis. Results: Three main themes emerged from the data around training, system-level factors, and practice-level factors that shaped how physicians are trained and practice medical cannabis certification. Although participants were largely satisfied with their CME training, they noted areas for improvement and a need for more high-quality research. Participants also noted system-level factors that prohibited treating cannabis as a traditional medical therapy, including communication barriers between physicians and dispensaries and confusion about insurance coverage for certification exams. Conclusion: Physicians require additional training to improve the operation of the medical cannabis program in Pennsylvania. Participants suggested that the program could be improved by reducing communication barriers between them, their patients, and the dispensaries around the product purchase, selection, use, and effectiveness of medical cannabis.
MeSH term(s)	Humans ; Medical Marijuana/therapeutic use ; Pennsylvania ; Physicians ; Cannabis ; Qualitative Research
Chemical Substances	Medical Marijuana
Language	English
Publishing date	2023-08-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2239939-2
ISSN	1558-7118 ; 1557-2625
ISSN (online)	1558-7118
ISSN	1557-2625
DOI	10.3122/jabfm.2022.220304R1
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Zs.A 2626: Show issues

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Article ; Online: Early Psychosis Intervention and Primary Care: A Mixed Methods Study of Family Physician Knowledge, Attitudes, Preferences, and Needs.

Carter, Brooke / Rodrigues, Rebecca / Edwards, Jordan / Jan, Saadia Hameed / Ryan, Bridget L / Booth, Richard G / Archie, Suzanne / Anderson, Kelly K

Community mental health journal

2024

Abstract: Family physicians (FPs) play an important but underappreciated role in the pathways to care for people with early psychosis. We conducted a mixed-methods study to describe the knowledge, attitudes, preferences, and needs of FPs towards the recognition ... ...

Abstract	Family physicians (FPs) play an important but underappreciated role in the pathways to care for people with early psychosis. We conducted a mixed-methods study to describe the knowledge, attitudes, preferences, and needs of FPs towards the recognition and management of early psychosis. We sent a cross-sectional postal survey to a random sample of FPs in Ontario, Canada, and conducted in-depth qualitative interviews with twenty. FPs were generally aware of important early psychosis symptoms, however, there were some knowledge gaps. Among surveyed FPs, 25% were unsure of the availability of early psychosis intervention services in their region, and most (80%) would prefer to co-manage with specialists. In the qualitative interviews, FPs expressed varied comfort levels in recognizing psychosis, and that timely access to psychiatry was a main concern. Our findings suggest that FPs require better support in recognizing and managing early psychosis and facilitating connections with specialized care.
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	215855-3
ISSN	1573-2789 ; 0010-3853
ISSN (online)	1573-2789
ISSN	0010-3853
DOI	10.1007/s10597-024-01242-1
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Zs.B 557: Show issues

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Article ; Online: A Proteomics Investigation of Salivary Profiles as Potential Biomarkers for Autism Spectrum Disorder (ASD).

Wormwood, Kelly L / Charette, Laci / Ryan, Jeanne P / Darie, Costel C / Woods, Alisa G

The protein journal

2023 Volume 42, Issue 5, Page(s) 607–620

Abstract: ... lactotransferrin, transferrin, polymeric immunoglobulin receptor, Ig A L, Ig J chain, mucin 5 AC, and lipocalin 1 ...

Abstract	Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that affects approximately 1/68 children, with a more recent study suggesting numbers as high as 1/36. According to Diagnostic and Statistical Manual of Mental Disorders, the etiology of ASD is unknown and diagnosis of this disorder is behavioral. There is currently no biomarker signature for ASD, however, identifying a biomarker signature is crucial as it would aid in diagnosis, identifying treatment targets, monitoring treatments, and identifying the etiology of the disorder. Here we used nanoliquid chromatography-tandem mass spectrometry (nanoLC-MS/MS) to investigate the saliva from individuals with ASD and matched controls in a 14 vs 14 study. We found numerous proteins to have statistically significant dysregulations, including lactotransferrin, transferrin, polymeric immunoglobulin receptor, Ig A L, Ig J chain, mucin 5 AC, and lipocalin 1 isoform X1. These findings are consistent with previous studies by our lab, and others, and point to dysregulations in the immune system, lipid metabolism and/or transport, and gastrointestinal disturbances, which are common and reoccurring topics in ASD research.
MeSH term(s)	Child ; Humans ; Autism Spectrum Disorder/diagnosis ; Autism Spectrum Disorder/metabolism ; Tandem Mass Spectrometry ; Proteomics ; Biomarkers ; Saliva
Chemical Substances	Biomarkers
Language	English
Publishing date	2023-08-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2143071-8
ISSN	1875-8355 ; 1572-3887
ISSN (online)	1875-8355
ISSN	1572-3887
DOI	10.1007/s10930-023-10146-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Multistate sensitivity monitoring of

Hamilton, Ryan / Jacobs, Janette L / McCoy, Austin Glenn / Kelly, Heather M / Bradley, Carl / Malvick, Dean / Rojas, J Alejandro / Chilvers, Martin I

Plant disease

2023

Abstract: Sudden death syndrome (SDS), caused ... ...

Abstract	Sudden death syndrome (SDS), caused by
Language	English
Publishing date	2023-12-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	754182-x
ISSN	0191-2917
ISSN	0191-2917
DOI	10.1094/PDIS-11-23-2465-RE
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Z 2043: Show issues

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Article ; Online: Pre-hibernation diet alters skeletal muscle relaxation kinetics, but not force development in torpid arctic ground squirrels.

Krishnan, Jishnu K S / Rice, Sarah / Mikes, Monica / Sugiura, M Hoshi / Drew, Kelly L / Barati, Zeinab / Oliver, S Ryan

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology

2024 Volume 194, Issue 1, Page(s) 65–79

Abstract: During the hibernation season, Arctic ground squirrels (AGS) experience extreme temperature fluctuations (body temperature, ... ...

Abstract	During the hibernation season, Arctic ground squirrels (AGS) experience extreme temperature fluctuations (body temperature, T
MeSH term(s)	Animals ; Temperature ; Muscle, Skeletal ; Sciuridae/physiology ; Diet/veterinary ; Muscle Relaxation
Language	English
Publishing date	2024-01-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	231245-1
ISSN	1432-136X ; 0174-1578
ISSN (online)	1432-136X
ISSN	0174-1578
DOI	10.1007/s00360-023-01527-z
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Uc I Zs.171: Show issues

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Article ; Online: Development of a novel five-dye panel for human identification insertion/deletion (INDEL) polymorphisms.

Avellaneda, Lucio L / Johnson, Damani T / Gutierrez, Ryan / Thompson, Lindsey / Sage, Kelly A / Sturm, Sarah A / Houston, Rachel M / LaRue, Bobby L

Journal of forensic sciences

2024 Volume 69, Issue 3, Page(s) 814–824

Abstract: DNA analysis of forensic case samples relies on short tandem repeats (STRs), a key component of the combined DNA index system (CODIS) used to identify individuals. However, limitations arise when dealing with challenging samples, prompting the ... ...

Abstract	DNA analysis of forensic case samples relies on short tandem repeats (STRs), a key component of the combined DNA index system (CODIS) used to identify individuals. However, limitations arise when dealing with challenging samples, prompting the exploration of alternative markers such as single nucleotide polymorphisms (SNPs) and insertion/deletion (INDELs) polymorphisms. Unlike SNPs, INDELs can be differentiated easily by size, making them compatible with electrophoresis methods. It is possible to design small INDEL amplicons (<200 bp) to enhance recovery from degraded samples. To this end, a set of INDEL Human Identification Markers (HID) was curated from the 1000 Genomes Project, employing criteria including a fixation index (F
MeSH term(s)	Humans ; INDEL Mutation ; DNA Fingerprinting/methods ; Gene Frequency ; Reproducibility of Results ; Genetic Markers ; Genotype ; Fluorescent Dyes ; Polymerase Chain Reaction ; Polymorphism, Genetic ; Electrophoresis, Capillary ; Microsatellite Repeats
Chemical Substances	Genetic Markers ; Fluorescent Dyes
Language	English
Publishing date	2024-01-30
Publishing country	United States
Document type	Journal Article ; Validation Study
ZDB-ID	219216-0
ISSN	1556-4029 ; 0022-1198
ISSN (online)	1556-4029
ISSN	0022-1198
DOI	10.1111/1556-4029.15475
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Zs.B 24: Show issues

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Article ; Online: Fertility Knowledge and Educational Experiences of Graduating Medical Students: A Multi-Institution Survey.

Hunt, Kelby N / Kelly, Amelia G / Faubion, Laura / Melikian, Ryan / Pearson, Claire / Plowden, Torie C / Files, Julia A / Chamorro Dauer, Laura V / Marshall, Ariela L / Blakemore, Jennifer K

Journal of women's health (2002)

2024

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2024-04-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	1139774-3
ISSN	1931-843X ; 1059-7115 ; 1540-9996
ISSN (online)	1931-843X
ISSN	1059-7115 ; 1540-9996
DOI	10.1089/jwh.2023.1016
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Zs.A 3584: Show issues

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Article ; Online: Open-tubular trap columns: towards simple and robust liquid chromatography separations for single-cell proteomics.

Webber, Kei G I / Huang, Siqi / Truong, Thy / Heninger, Jacob L / Gregus, Michal / Ivanov, Alexander R / Kelly, Ryan T

Molecular omics

2024 Volume 20, Issue 3, Page(s) 184–191

Abstract: Nanoflow liquid chromatography-mass spectrometry is key to enabling in-depth proteome profiling of trace samples, including single cells, but these separations can lack robustness due to the use of narrow-bore columns that are susceptible to clogging. In ...

Abstract	Nanoflow liquid chromatography-mass spectrometry is key to enabling in-depth proteome profiling of trace samples, including single cells, but these separations can lack robustness due to the use of narrow-bore columns that are susceptible to clogging. In the case of single-cell proteomics, offline cleanup steps are generally omitted to avoid losses to additional surfaces, and online solid-phase extraction/trap columns frequently provide the only opportunity to remove salts and insoluble debris before the sample is introduced to the analytical column. Trap columns are traditionally short, packed columns used to load and concentrate analytes at flow rates greater than those employed in analytical columns, and since these first encounter the uncleaned sample mixture, trap columns are also susceptible to clogging. We hypothesized that clogging could be avoided by using large-bore porous layer open tubular trap columns (PLOTrap). The low back pressure ensured that the PLOTraps could also serve as the sample loop, thus allowing sample cleanup and injection with a single 6-port valve. We found that PLOTraps could effectively remove debris to avoid column clogging. We also evaluated multiple stationary phases and PLOTrap diameters to optimize performance in terms of peak widths and sample loading capacities. Optimized PLOTraps were compared to conventional packed trap columns operated in forward and backflush modes, and were found to have similar chromatographic performance of backflushed traps while providing improved debris removal for robust analysis of trace samples.
MeSH term(s)	Proteomics/methods ; Chromatography, Liquid ; Liquid Chromatography-Mass Spectrometry
Language	English
Publishing date	2024-03-25
Publishing country	England
Document type	Journal Article
ISSN	2515-4184
ISSN (online)	2515-4184
DOI	10.1039/d3mo00249g
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