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  1. Book ; Online: Innate Immunity Pathways in Autoimmune Diseases

    Zouali, Moncef / La Cava, Antonio

    2019  

    Keywords Medicine ; Immunology ; toll-like receptor ; dendritic cells ; innate-like B cells ; extracellular vesicle ; semaphorin ; lupus ; arthritis ; calcium-dependent peptidyl-arginine deiminase
    Size 1 electronic resource (124 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231499
    ISBN 9782889632367 ; 2889632369
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Considerations on COVID-19 vaccination.

    La Cava, Antonio

    Clinical immunology communications

    2023  Volume 3, Page(s) 77–78

    Language English
    Publishing date 2023-06-10
    Publishing country United States
    Document type Editorial
    ISSN 2772-6134
    ISSN (online) 2772-6134
    DOI 10.1016/j.clicom.2023.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Low-dose interleukin-2 therapy in systemic lupus erythematosus.

    La Cava, Antonio

    Rheumatology and immunology research

    2023  Volume 4, Issue 3, Page(s) 150–156

    Abstract: In systemic lupus erythematosus (SLE), T regulatory cells ( ... ...

    Abstract In systemic lupus erythematosus (SLE), T regulatory cells (T
    Language English
    Publishing date 2023-09-27
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2719-4523
    ISSN (online) 2719-4523
    DOI 10.2478/rir-2023-0021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Systemic Lupus Erythematosus and Coronavirus Disease 2019.

    Cava, Antonio La

    Rheumatology and immunology research

    2021  Volume 2, Issue 1, Page(s) 15–18

    Abstract: Coronavirus disease 2019 (COVID-19) is a contagious infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It manifests with variable clinical pictures ranging from asymptomatic to mild or uncomplicated illness to ... ...

    Abstract Coronavirus disease 2019 (COVID-19) is a contagious infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It manifests with variable clinical pictures ranging from asymptomatic to mild or uncomplicated illness to severe disease with possible multi-organ involvement, with respiratory and vascular systems being the most often affected. Since COVID-19 can affect patients with autoimmune rheumatic conditions, the concomitant presence of two diseases may have clinical characteristics whose knowledge may help facilitate clinical management. This review discusses the data available in the literature on COVID-19 in systemic lupus erythematosus (SLE) patients.
    Language English
    Publishing date 2021-04-13
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2719-4523
    ISSN (online) 2719-4523
    DOI 10.2478/rir-2021-0004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Antiphospholipid antibodies and COVID-19.

    La Cava, Antonio

    Autoimmunity reviews

    2021  Volume 20, Issue 10, Page(s) 102910

    MeSH term(s) Antibodies, Antiphospholipid ; Antiphospholipid Syndrome/diagnosis ; COVID-19 ; Humans ; SARS-CoV-2
    Chemical Substances Antibodies, Antiphospholipid
    Language English
    Publishing date 2021-07-22
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2144145-5
    ISSN 1873-0183 ; 1568-9972
    ISSN (online) 1873-0183
    ISSN 1568-9972
    DOI 10.1016/j.autrev.2021.102910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5913: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Editorial overview: Research progress in autoimmunity: an overview and update.

    La Cava, Antonio

    Current opinion in immunology

    2020  Volume 67, Page(s) iii–v

    MeSH term(s) Autoimmune Diseases/immunology ; Autoimmunity/immunology ; Humans
    Language English
    Publishing date 2020-12-15
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1035767-1
    ISSN 1879-0372 ; 0952-7915
    ISSN (online) 1879-0372
    ISSN 0952-7915
    DOI 10.1016/j.coi.2020.11.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2773: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    Zs.MG 13: Show issues

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  7. Article: The Influence of Diet and Obesity on Gene Expression in SLE.

    La Cava, Antonio

    Genes

    2019  Volume 10, Issue 5

    Abstract: This review provides an overview of the known effects of diet, obesity, and the intake of different nutrients on systemic lupus erythematosus (SLE). It summarizes and discusses the studies in rodents that identified how different diets can regulate gene ... ...

    Abstract This review provides an overview of the known effects of diet, obesity, and the intake of different nutrients on systemic lupus erythematosus (SLE). It summarizes and discusses the studies in rodents that identified how different diets can regulate gene expression in the disease, together with a description of the effects of diet on lupus patients' inflammatory state and disease severity. The identification of selected dietary candidates that can modulate SLE onset and progression is analyzed in relation to possible targeted approaches that could ultimately ameliorate the management and prognosis of this disease.
    MeSH term(s) Diet ; Disease Progression ; Gene Expression Regulation/genetics ; Humans ; Inflammation/diet therapy ; Inflammation/genetics ; Inflammation/pathology ; Lupus Erythematosus, Systemic/diet therapy ; Lupus Erythematosus, Systemic/genetics ; Lupus Erythematosus, Systemic/pathology ; Nutrients/genetics ; Nutrients/therapeutic use ; Obesity/diet therapy ; Obesity/genetics ; Obesity/pathology
    Language English
    Publishing date 2019-05-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527218-4
    ISSN 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes10050405
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Human T cell repertoire: what happens in thymus does not stay in thymus.

    La Cava, Antonio

    The Journal of clinical investigation

    2019  Volume 129, Issue 6, Page(s) 2195–2197

    Abstract: The T cell receptor (TCR) repertoire is diverse, thus allowing recognition of a wide range of pathogens by T cells. In humans, the study of the formation of TCR repertoires is problematic because of the difficulty in performing investigations in vivo. In ...

    Abstract The T cell receptor (TCR) repertoire is diverse, thus allowing recognition of a wide range of pathogens by T cells. In humans, the study of the formation of TCR repertoires is problematic because of the difficulty in performing investigations in vivo. In this issue of the JCI, Khosravi-Maharlooei and colleagues describe a new humanized mouse model that allows direct investigations on this topic. Using high-throughput and single-cell TCR-complementarity-determining region 3 β (TCR-CDR3β) sequencing, the authors were able to demonstrate that human thymic selection is a major driver of TCR sequence sharing, also implicating a preferential selection of shared cross-reactive CDR3βs during repertoire formation.
    MeSH term(s) Animals ; Complementarity Determining Regions ; Cross Reactions ; Humans ; Mice ; Receptors, Antigen, T-Cell, alpha-beta ; T-Lymphocytes
    Chemical Substances Complementarity Determining Regions ; Receptors, Antigen, T-Cell, alpha-beta
    Language English
    Publishing date 2019-05-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI128371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.184: Show issues Location:
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  9. Article ; Online: Editorial: Innate Immunity Pathways in Autoimmune Diseases.

    Zouali, Moncef / La Cava, Antonio

    Frontiers in immunology

    2019  Volume 10, Page(s) 1245

    MeSH term(s) Autoimmune Diseases ; Extracellular Vesicles ; Humans ; Immunity, Innate ; Mesenchymal Stem Cells ; Multiple Sclerosis
    Language English
    Publishing date 2019-06-04
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2019.01245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Tregs in SLE: an Update.

    La Cava, Antonio

    Current rheumatology reports

    2018  Volume 20, Issue 2, Page(s) 6

    Abstract: Purpose of review: There has been great interest in understanding why T regulatory cells (Tregs) are reduced in number and/or in function in several autoimmune diseases including systemic lupus erythematosus (SLE). Although research has provided some ... ...

    Abstract Purpose of review: There has been great interest in understanding why T regulatory cells (Tregs) are reduced in number and/or in function in several autoimmune diseases including systemic lupus erythematosus (SLE). Although research has provided some answers, there is still much to learn.
    Recent findings: Recent investigations on the mechanisms responsible for the impairment of the Tregs in SLE have identified relevant abnormalities in cellular and molecular pathways that have been instrumental in the design of studies in animal models and in the development of pilot immunotherapeutic studies in lupus patients. We review the progress made in the field in the last 5 years, discussing the mechanistic studies, together with the preclinical and clinical works that are moving forward the understanding of the physiopathology of Tregs in SLE.
    MeSH term(s) Animals ; Epigenesis, Genetic ; Humans ; Immune Tolerance/immunology ; Interleukin-2/therapeutic use ; Lupus Erythematosus, Systemic/drug therapy ; Lupus Erythematosus, Systemic/genetics ; Lupus Erythematosus, Systemic/immunology ; T-Lymphocyte Subsets/immunology ; T-Lymphocytes, Regulatory/immunology
    Chemical Substances Interleukin-2
    Language English
    Publishing date 2018-02-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057357-1
    ISSN 1534-6307 ; 1523-3774
    ISSN (online) 1534-6307
    ISSN 1523-3774
    DOI 10.1007/s11926-018-0714-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5531: Show issues Location:
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