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  1. Article: [Textual research on the author of manuscript prefaces in Zhao Kaimei's version of Zhong Jing Quan Shu collected at the Library of Palace Museum in Taipei].

    You, Wen-ren / Su, Yi-zhan

    Zhonghua yi shi za zhi (Beijing, China : 1980)

    2007  Volume 37, Issue 2, Page(s) 98–103

    Abstract: Zhong Jing Quan Shu (Zhongjing's Complete Book) published by Zhao Kaimei in the Ming dynasty is ... to that of the edition of the Northern Song dynasty. Therefore, there are two manuscript prefaces found in the Zhong Jing ...

    Abstract Zhong Jing Quan Shu (Zhongjing's Complete Book) published by Zhao Kaimei in the Ming dynasty is very important. In our understanding, the part of this book named Shang Han Lun (Treatise on Exogenous Cold Diseases) has been thought that the edition could be possibly the most similar to that of the edition of the Northern Song dynasty. Therefore, there are two manuscript prefaces found in the Zhong Jing Quan Shu collected at the Library of Palace Museum in Taipei. The message from the writer of the manuscript who owned facsimile handwritten copy of the official Northern Song large-character edition of Shang Han Lun. This is the first time to reveal that a paper record has been kept in the world now since the Ming dynasty. That is the reason why the edition has always been thought so much important to the world now. These manuscript prefaces quite often attracted the attention of the Chinese and Japanese scholars, but none of them could identify who the writer was. And after a thorough reading of the original work, investigating the inscriptions, and checking the seals, we finally identified the writer to be Xu Fang, in late Qing dynasty. The result of this study might be helpful to research the tracing of the valuable facsimile handwritten copy of the official Northern Song large-character edition of Shang Han Lun, and also would be possible to give some new ideas and make new contents of Shang Han Lun to the studies of bibliography and editions in the future.
    MeSH term(s) Books ; China ; Museums
    Language Chinese
    Publishing date 2007-04
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1052411-3
    ISSN 0255-7053
    ISSN 0255-7053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Selected age-diagnostic datums of ODP Site 184-1148, supplementary data to: Li, Qianyu; Wang, Pinxian; Zhao, Quanhong; Shao, Lei; Zhong, Guangfa; Tian, Jun; Cheng, Xinrong; Jian, Zhimin; Su, Xin (2006): A 33 Ma lithostratigraphic record of tectonic and paleoceanographic evolution of the South China Sea. Marine Geology, 230(3-4), 217-235

    Li, Qianyu / Cheng, Xinrong / Jian, Zhimin / Shao, Lei / Su, Xin / Tian, Jun / Wang, Pinxian / Zhao, Quanhong / Zhong, Guangfa

    2006  

    Abstract: The 853 m thick sediment sequence recovered at ODP Site 1148 provides an unprecedented record of tectonic and paleoceanographic evolution in the South China Sea over the past 33 Ma. Litho-, bio-, and chemo-stratigraphic studies helped identify six ... ...

    Abstract The 853 m thick sediment sequence recovered at ODP Site 1148 provides an unprecedented record of tectonic and paleoceanographic evolution in the South China Sea over the past 33 Ma. Litho-, bio-, and chemo-stratigraphic studies helped identify six periods of changes marking the major steps of the South China Sea geohistory. Rapid deposition with sedimentation rates of 60 m/Ma or more characterized the early Oligocene rifting. Several unconformities from the slumped unit between 457 and 495 mcd together erased about 3 Ma late Oligocene record, providing solid evidence of tectonic transition from rifting/slow spreading to rapid spreading in the South China Sea. Slow sedimentation of ~20-30 m/Ma signifies stable seafloor spreading in the early Miocene. Dissolution may have affected the completeness of Miocene-Pleistocene succession with short-term hiatuses beyond current biostratigraphical resolution. Five major dissolution events, D-1 to D-5, characterize the stepwise development of deep water masses in close association to post-Oligocene South China Sea basin transformation. The concurrence of local and global dissolution events in the Miocene and Pliocene suggests climatic forcing as the main mechanism causing deep water circulation changes concomitantly in world oceans and in marginal seas. A return of high sedimentation rate of 60 m/Ma to the late Pliocene and Pleistocene South China Sea was caused by intensified down-slope transport due to frequent sea level fluctuations and exposure of a large shelf area during sea level low-stands. The six paleoceanographic stages, respectively corresponding to rifting (~33-28.5 Ma), changing spreading southward (28.5-23 Ma), stable spreading to end of spreading (23-15 Ma), post-spreading balance (15-9 Ma), further modification and monsoon influence (9-5 Ma), and glacial prevalence (5-0 Ma), had transformed the South China Sea from a series of deep grabens to a rapidly expanding open gulf and finally to a semi-enclosed marginal sea in the past 33 Ma.
    Language English
    Dates of publication 2006-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/j.margeo.2006.05.006
    DOI 10.1594/PANGAEA.724457
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article ; Online: Insights into the Mechanism of Nitrobenzene Reduction to Aniline by Phosphomolybdic Acid Supported TM

    Zhao, Cong Cong / Wang, Shuang / Yan, Li Kai / Su, Zhong Min

    Inorganic chemistry

    2024  Volume 63, Issue 4, Page(s) 1784–1792

    Abstract: Catalytic hydrogenation of nitrobenzene (Ph- ... ...

    Abstract Catalytic hydrogenation of nitrobenzene (Ph-NO
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.3c03106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Case report: Overlapping anti-AMPAR encephalitis with anti-IgLON5 disease post herpes simplex virus encephalitis.

    Sun, Shihui / Ren, Jiafeng / Zhong, Zhao / Ma, Xuxia / Shang, Danqing / Su, Changjun / Zhao, Xianchao

    Frontiers in immunology

    2024  Volume 14, Page(s) 1329540

    Abstract: Autoimmune encephalitis (AE) is the result of an autoimmune process that occurs as a rapidly advancing encephalopathy. Autoimmune encephalitis was commonly linked to herpes simplex virus 1 (HSV-1) as the most frequently identified virus. The main areas ... ...

    Abstract Autoimmune encephalitis (AE) is the result of an autoimmune process that occurs as a rapidly advancing encephalopathy. Autoimmune encephalitis was commonly linked to herpes simplex virus 1 (HSV-1) as the most frequently identified virus. The main areas affected by this invasion are the temporal lobe, frontal lobe, and limbic system. Limbic encephalitis is a highly uncommon occurrence involving anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) encephalitis and anti-IgLON family member 5 (IgLON5) disease, both belonging to the rare category. As far as we know, this is the first report showing that a patient diagnosed with AMPAR encephalitis overlapped with anti-IgLON5 disease post herpes simplex virus encephalitis (HSE), which helps to broaden the range of this uncommon autoimmune disease. We recommend autoantibody testing in all patients with HSE, particularly those involving neurological relapses or progression.
    MeSH term(s) Humans ; Brain Diseases ; Cell Adhesion Molecules, Neuronal ; Encephalitis, Herpes Simplex/drug therapy ; Hashimoto Disease ; Herpesvirus 1, Human
    Chemical Substances Cell Adhesion Molecules, Neuronal ; IgLON5 protein, human
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1329540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Micro-Leakage Image Recognition Method for Internal Detection in Small, Buried Gas Pipelines.

    Zhao, Yuxin / Su, Zhong / Zhao, Hui

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 8

    Abstract: In order to resolve the problem that the sample of image for internal detection of DN100 buried gas pipeline microleakage is single and difficult to identify, a recognition method of microleakage image of the pipeline internal detection robot is proposed. ...

    Abstract In order to resolve the problem that the sample of image for internal detection of DN100 buried gas pipeline microleakage is single and difficult to identify, a recognition method of microleakage image of the pipeline internal detection robot is proposed. First, nongenerative data augmentation is used to expand the microleakage images of gas pipelines. Secondly, a generative data augmentation network, Deep Convolutional Wasserstein Generative Adversarial Networks (DCWGANs), is designed to generate microleakage images with different features for detection in the pipeline of gas pipelines to achieve sample diversity of microleakage images of gas pipelines. Then, a bi-directional feature pyramid network (BiFPN) is introduced into You Only Look Once (YOLOv5) to retain more deep feature information by adding cross-scale connecting lines in the feature fusion structure; finally, a small target detection layer is constructed in YOLOv5 so that more shallow feature information can be retained to achieve small-scale leak point recognition. The experimental results show that the precision of this method for microleak identification is 95.04%, the recall rate is 94.86%, the mAP value is 96.31%, and the minimum size of identifiable leaks is 1 mm.
    Language English
    Publishing date 2023-04-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23083956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Differential value of PGI, PGII and G-17 in chronic atrophic gastritis and early gastric cancer.

    Shang, Xidan / Zhao, Yijing / Xu, Tingting / Ma, Qun / Su, Zhong

    Minerva pediatrics

    2023  Volume 75, Issue 5, Page(s) 753–755

    Language English
    Publishing date 2023-05-08
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062664-X
    ISSN 2724-5780
    ISSN (online) 2724-5780
    DOI 10.23736/S2724-5276.23.07261-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nano-PROTACs: state of the art and perspectives.

    Zhong, Jie / Zhao, Ruiqi / Wang, Yuji / Su, Yu-Xiong / Lan, Xinmiao

    Nanoscale

    2024  Volume 16, Issue 9, Page(s) 4378–4391

    Abstract: PROteolysis TArgeting Chimeras (PROTACs), as a recently identified technique in the field of new drug development, provide new concepts for disease treatment and are expected to revolutionize drug discovery. With high specificity and flexibility, PROTACs ...

    Abstract PROteolysis TArgeting Chimeras (PROTACs), as a recently identified technique in the field of new drug development, provide new concepts for disease treatment and are expected to revolutionize drug discovery. With high specificity and flexibility, PROTACs serve as an innovative research tool to target and degrade disease-relevant proteins that are not currently pharmaceutically vulnerable to eliminating their functions by hijacking the ubiquitin-proteasome system. To date, PROTACs still face the challenges of low solubility, poor permeability, off-target effects, and metabolic instability. The combination of nanotechnology and PROTACs has been explored to enhance the
    MeSH term(s) Proteolysis ; Proteolysis Targeting Chimera ; Proteasome Endopeptidase Complex/metabolism ; Proteins/metabolism ; Drug Discovery/methods
    Chemical Substances Proteolysis Targeting Chimera ; Proteasome Endopeptidase Complex (EC 3.4.25.1) ; Proteins
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr06059d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pulmonary complications after Stanford type A aortic dissection surgery: a comprehensive analysis and literature review.

    Zhong, Wei / Zhao, Bo / Zhou, Junhui / Yang, Chen / Su, Mengqin / Meng, Xianhui

    Panminerva medica

    2023  

    Language English
    Publishing date 2023-09-07
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123572-2
    ISSN 1827-1898 ; 0031-0808
    ISSN (online) 1827-1898
    ISSN 0031-0808
    DOI 10.23736/S0031-0808.23.04923-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Multi-Omics Approach Reveals

    Zhao, Tianqi / Tang, Ping / Liu, Chonglan / Zuo, Rubin / Su, Shunyu / Zhong, Yuanyuan / Li, Yongjie / Yang, Jing

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 3, Page(s) 1822–1843

    Abstract: Rice ( ...

    Abstract Rice (
    MeSH term(s) Plant Proteins/metabolism ; Oryza/metabolism ; Multiomics ; Plant Breeding ; Transcription Factors/genetics ; Disease Resistance/genetics ; Magnaporthe ; Plant Diseases/genetics ; Gene Expression Regulation, Plant
    Chemical Substances Plant Proteins ; Transcription Factors
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c07330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Hypersampsonone H attenuates ulcerative colitis via inhibition of PDE4 and regulation of cAMP/PKA/CREB signaling pathway.

    Li, Yanzhen / Wang, Mingqiang / Su, Jianhui / Zhong, Ruimin / Yin, Sheng / Zhao, Zhongxiang / Sun, Zhanghua

    International immunopharmacology

    2024  Volume 128, Page(s) 111490

    Abstract: Background and objectives: Ulcerative colitis (UC) is a recurrent intestinal inflammatory disease which poses a serious threat to the life of patients. However, there are no specific drugs for UC yet. Hypericum sampsonii Hance (HS) is a Chinese herbal ... ...

    Abstract Background and objectives: Ulcerative colitis (UC) is a recurrent intestinal inflammatory disease which poses a serious threat to the life of patients. However, there are no specific drugs for UC yet. Hypericum sampsonii Hance (HS) is a Chinese herbal medicine traditionally used to treat enteritis and dysentery. Our previous studies have demonstrated that HS holds potential anti-UC effects, and a novel compound named Hypersampsonone H (HS-1) isolated from HS possesses significant anti-inflammatory activity. However, the beneficial effects of HS-1 on UC remain unclear. This study aimed to investigate the therapeutic effects of HS-1 on UC and its potential mechanisms, both in vitro and in vivo.
    Methods: The in vitro model was employed using LPS-induced RAW264.7 cells to investigate the anti-inflammatory effects of HS-1 and its possible mechanisms. Furthermore, the therapeutic efficacy and potential mechanisms of HS-1 against dextran sulfate sodium (DSS)-induced acute colitis were assessed through histopathological examination, biochemical analysis, and molecular docking.
    Results: In vitro, HS-1 significantly reduced LPS-induced inflammatory responses, as indicated by inhibiting NO production, down-regulating the overexpression of COX-2 and iNOS, as well as regulating the imbalanced levels of IL-6, TNF-α, and IL-10. Moreover, HS-1 also inhibited the expression of PDE4, elevated the intracellular cAMP level, and promoted the phosphorylation of CREB, thereby activating the PKA/CREB pathway in RAW264.7 cells. In vivo, HS-1 demonstrated therapeutic capacity against DSS-induced colitis by alleviating the symptoms of colitis mice, regulating the abnormal expression of inflammatory mediators, protecting the integrity of intestinal epithelial barrier, and reducing tissue fibrosis. Consistently, HS-1 was found to decrease the expression of PDE4 isoforms, subsequently activating the cAMP/PKA/CREB signaling pathway. Furthermore, the molecular docking results indicated that HS-1 exhibited a high affinity for PDE4, particularly PDE4D. Further mechanistic validation in vitro demonstrated that HS-1 possessed a synergistic effect on forskolin and an antagonistic effect on H-89 dihydrochloride, thereby exerting anti-inflammatory effects through the cAMP/PKA/CREB signaling pathway.
    Conclusion: We disclose that HS-1 serves as a promising candidate drug for the treatment of UC by virtue of its ability to reduce DSS-induced colitis via the inhibition of PDE4 and the activation of cAMP/PKA/CREB signaling pathway.
    MeSH term(s) Humans ; Mice ; Animals ; Colitis, Ulcerative/drug therapy ; Lipopolysaccharides/pharmacology ; Molecular Docking Simulation ; Signal Transduction ; Colitis/chemically induced ; Anti-Inflammatory Agents/therapeutic use ; Dextran Sulfate/pharmacology ; Disease Models, Animal ; Mice, Inbred C57BL ; Colon/pathology
    Chemical Substances Lipopolysaccharides ; Anti-Inflammatory Agents ; Dextran Sulfate (9042-14-2)
    Language English
    Publishing date 2024-01-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2024.111490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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