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  1. Article: Measurement of inelastic, single- and double-diffraction cross sections in proton-proton collisions at the LHC with ALICE.

    Abelev, B / Adam, J / Adamová, D / Adare, A M / Aggarwal, M M / Aglieri Rinella, G / Agocs, A G / Agostinelli, A / Aguilar Salazar, S / Ahammed, Z / Ahmad Masoodi, A / Ahmad, N / Ahn, S A / Ahn, S U / Akindinov, A / Aleksandrov, D / Alessandro, B / Alfaro Molina, R / Alici, A /
    Alkin, A / Almaráz Aviña, E / Alme, J / Alt, T / Altini, V / Altinpinar, S / Altsybeev, I / Andrei, C / Andronic, A / Anguelov, V / Anielski, J / Anson, C / Antičić, T / Antinori, F / Antonioli, P / Aphecetche, L / Appelshäuser, H / Arbor, N / Arcelli, S / Arend, A / Armesto, N / Arnaldi, R / Aronsson, T / Arsene, I C / Arslandok, M / Asryan, A / Augustinus, A / Averbeck, R / Awes, T C / Äystö, J / Azmi, M D / Bach, M / Badalà, A / Baek, Y W / Bailhache, R / Bala, R / Baldini Ferroli, R / Baldisseri, A / Baldit, A / Baltasar Dos Santos Pedrosa, F / Bán, J / Baral, R C / Barbera, R / Barile, F / Barnaföldi, G G / Barnby, L S / Barret, V / Bartke, J / Basile, M / Bastid, N / Basu, S / Bathen, B / Batigne, G / Batyunya, B / Baumann, C / Bearden, I G / Beck, H / Behera, N K / Belikov, I / Bellini, F / Bellwied, R / Belmont-Moreno, E / Bencedi, G / Beole, S / Berceanu, I / Bercuci, A / Berdnikov, Y / Berenyi, D / Bergognon, A A E / Berzano, D / Betev, L / Bhasin, A / Bhati, A K / Bhom, J / Bianchi, N / Bianchi, L / Bianchin, C / Bielčík, J / Bielčíková, J / Bilandzic, A / Bjelogrlic, S / Blanco, F / Blau, D / Blume, C / Boccioli, M / Bock, N / Böttger, S / Bogdanov, A / Bøggild, H / Bogolyubsky, M / Boldizsár, L / Bombara, M / Book, J / Borel, H / Borissov, A / Bose, S / Bossú, F / Botje, M / Botta, E / Boyer, B / Braidot, E / Braun-Munzinger, P / Bregant, M / Breitner, T / Browning, T A / Broz, M / Brun, R / Bruna, E / Bruno, G E / Budnikov, D / Buesching, H / Bufalino, S / Busch, O / Buthelezi, Z / Caballero Orduna, D / Caffarri, D / Cai, X / Caines, H / Calvo Villar, E / Camerini, P / Canoa Roman, V / Cara Romeo, G / Carena, F / Carena, W / Carlin Filho, N / Carminati, F / Casanova Díaz, A / Castillo Castellanos, J / Castillo Hernandez, J F / Casula, E A R / Catanescu, V / Cavicchioli, C / Ceballos Sanchez, C / Cepila, J / Cerello, P / Chang, B / Chapeland, S / Charvet, J L / Chattopadhyay, S / Chawla, I / Cherney, M / Cheshkov, C / Cheynis, B / Chibante Barroso, V / Chinellato, D D / Chochula, P / Chojnacki, M / Choudhury, S / Christakoglou, P / Christensen, C H / Christiansen, P / Chujo, T / Chung, S U / Cicalo, C / Cifarelli, L / Cindolo, F / Cleymans, J / Coccetti, F / Colamaria, F / Colella, D / Conesa Balbastre, G / Conesa Del Valle, Z / Constantin, P / Contin, G / Contreras, J G / Cormier, T M / Corrales Morales, Y / Cortese, P / Cortés Maldonado, I / Cosentino, M R / Costa, F / Cotallo, M E / Crescio, E / Crochet, P / Cruz Alaniz, E / Cuautle, E / Cunqueiro, L / Dainese, A / Dalsgaard, H H / Danu, A / Das, D / Das, K / Das, I / Dash, S / Dash, A / De, S / de Barros, G O V / De Caro, A / de Cataldo, G / de Cuveland, J / De Falco, A / De Gruttola, D / Delagrange, H / Deloff, A / Demanov, V / De Marco, N / Dénes, E / De Pasquale, S / Deppman, A / D Erasmo, G / de Rooij, R / Diaz Corchero, M A / Di Bari, D / Dietel, T / Di Giglio, C / Di Liberto, S / Di Mauro, A / Di Nezza, P / Divià, R / Djuvsland, Ø / Dobrin, A / Dobrowolski, T / Domínguez, I / Dönigus, B / Dordic, O / Driga, O / Dubey, A K / Dubla, A / Ducroux, L / Dupieux, P / Dutta Majumdar, M R / Dutta Majumdar, A K / Elia, D / Emschermann, D / Engel, H / Erazmus, B / Erdal, H A / Espagnon, B / Estienne, M / Esumi, S / Evans, D / Eyyubova, G / Fabris, D / Faivre, J / Falchieri, D / Fantoni, A / Fasel, M / Fearick, R / Fedunov, A / Fehlker, D / Feldkamp, L / Felea, D / Fenton-Olsen, B / Feofilov, G / Fernández Téllez, A / Ferretti, A / Ferretti, R / Festanti, A / Figiel, J / Figueredo, M A S / Filchagin, S / Finogeev, D / Fionda, F M / Fiore, E M / Floris, M / Foertsch, S / Foka, P / Fokin, S / Fragiacomo, E / Francescon, A / Frankenfeld, U / Fuchs, U / Furget, C / Fusco Girard, M / Gaardhøje, J J / Gagliardi, M / Gago, A / Gallio, M / Gangadharan, D R / Ganoti, P / Garabatos, C / Garcia-Solis, E / Garishvili, I / Gerhard, J / Germain, M / Geuna, C / Gheata, M / Gheata, A / Ghidini, B / Ghosh, P / Gianotti, P / Girard, M R / Giubellino, P / Gladysz-Dziadus, E / Glässel, P / Gomez, R / Ferreiro, E G / González-Trueba, L H / González-Zamora, P / Gorbunov, S / Goswami, A / Gotovac, S / Grabski, V / Graczykowski, L K / Grajcarek, R / Grelli, A / Grigoras, C / Grigoras, A / Grigoriev, V / Grigoryan, S / Grigoryan, A / Grinyov, B / Grion, N / Gros, P / Grosse-Oetringhaus, J F / Grossiord, J-Y / Grosso, R / Guber, F / Guernane, R / Guerra Gutierrez, C / Guerzoni, B / Guilbaud, M / Gulbrandsen, K / Gunji, T / Gupta, A / Gupta, R / Gutbrod, H / Haaland, Ø / Hadjidakis, C / Haiduc, M / Hamagaki, H / Hamar, G / Han, B H / Hanratty, L D / Hansen, A / Harmanová-Tóthová, Z / Harris, J W / Hartig, M / Hasegan, D / Hatzifotiadou, D / Hayrapetyan, A / Heckel, S T / Heide, M / Helstrup, H / Herghelegiu, A / Herrera Corral, G / Herrmann, N / Hess, B A / Hetland, K F / Hicks, B / Hille, P T / Hippolyte, B / Horaguchi, T / Hori, Y / Hristov, P / Hřivnáčová, I / Huang, M / Humanic, T J / Hwang, D S / Ichou, R / Ilkaev, R / Ilkiv, I / Inaba, M / Incani, E / Innocenti, P G / Innocenti, G M / Ippolitov, M / Irfan, M / Ivan, C / Ivanov, A / Ivanov, M / Ivanov, V / Ivanytskyi, O / Jachołkowski, A / Jacobs, P M / Jang, H J / Janik, R / Janik, M A / Jayarathna, P H S Y / Jena, S / Jha, D M / Jimenez Bustamante, R T / Jirden, L / Jones, P G / Jung, H / Jusko, A / Kaidalov, A B / Kakoyan, V / Kalcher, S / Kaliňák, P / Kalliokoski, T / Kalweit, A / Kang, J H / Kaplin, V / Karasu Uysal, A / Karavichev, O / Karavicheva, T / Karpechev, E / Kazantsev, A / Kebschull, U / Keidel, R / Khan, P / Khan, S A / Khan, M M / Khanzadeev, A / Kharlov, Y / Kileng, B / Kim, S / Kim, B / Kim, T / Kim, D J / Kim, D W / Kim, J H / Kim, J S / Kim, M / Kirsch, S / Kisel, I / Kiselev, S / Kisiel, A / Klay, J L / Klein, J / Klein-Bösing, C / Kliemant, M / Kluge, A / Knichel, M L / Knospe, A G / Koch, K / Köhler, M K / Kollegger, T / Kolojvari, A / Kondratiev, V / Kondratyeva, N / Konevskikh, A / Korneev, A / Kour, R / Kowalski, M / Kox, S / Koyithatta Meethaleveedu, G / Kral, J / Králik, I / Kramer, F / Kraus, I / Krawutschke, T / Krelina, M / Kretz, M / Krivda, M / Krizek, F / Krus, M / Kryshen, E / Krzewicki, M / Kucheriaev, Y / Kugathasan, T / Kuhn, C / Kuijer, P G / Kulakov, I / Kumar, J / Kurashvili, P / Kurepin, A B / Kurepin, A / Kuryakin, A / Kushpil, V / Kushpil, S / Kvaerno, H / Kweon, M J / Kwon, Y / Ladrón de Guevara, P / Lakomov, I / Langoy, R / La Pointe, S L / Lara, C / Lardeux, A / La Rocca, P / Lea, R / Le Bornec, Y / Lechman, M / Lee, S C / Lee, G R / Lee, K S / Lefèvre, F / Lehnert, J / Lenhardt, M / Lenti, V / León, H / Leoncino, M / León Monzón, I / León Vargas, H / Lévai, P / Lien, J / Lietava, R / Lindal, S / Lindenstruth, V / Lippmann, C / Lisa, M A / Liu, L / Loggins, V R / Loginov, V / Lohn, S / Lohner, D / Loizides, C / Loo, K K / Lopez, X / López Torres, E / Løvhøiden, G / Lu, X-G / Luettig, P / Lunardon, M / Luo, J / Luparello, G / Luquin, L / Luzzi, C / Ma, K / Ma, R / Madagodahettige-Don, D M / Maevskaya, A / Mager, M / Mahapatra, D P / Maire, A / Malaev, M / Maldonado Cervantes, I / Malinina, L / Mal'Kevich, M V D / Malzacher, P / Mamonov, A / Mangotra, L / Manko, V / Manso, F / Manzari, V / Mao, Y / Marchisone, M / Mareš, J / Margagliotti, G V / Margotti, A / Marín, A / Marin Tobon, C A / Markert, C / Marquard, M / Martashvili, I / Martinengo, P / Martínez, M I / Martínez Davalos, A / Martínez García, G / Martynov, Y / Mas, A / Masciocchi, S / Masera, M / Masoni, A / Massacrier, L / Mastroserio, A / Matthews, Z L / Matyja, A / Mayer, C / Mazer, J / Mazzoni, M A / Meddi, F / Menchaca-Rocha, A / Mercado Pérez, J / Meres, M / Miake, Y / Milano, L / Milosevic, J / Mischke, A / Mishra, A N / Miśkowiec, D / Mitu, C / Mlynarz, J / Mohanty, B / Molnar, L / Montaño Zetina, L / Monteno, M / Montes, E / Moon, T / Morando, M / Moreira De Godoy, D A / Moretto, S / Morsch, A / Muccifora, V / Mudnic, E / Muhuri, S / Mukherjee, M / Müller, H / Munhoz, M G / Musa, L / Musso, A / Nandi, B K / Nania, R / Nappi, E / Nattrass, C / Naumov, N P / Navin, S / Nayak, T K / Nazarenko, S / Nazarov, G / Nedosekin, A / Nicassio, M / Niculescu, M / Nielsen, B S / Niida, T / Nikolaev, S / Nikolic, V / Nikulin, S / Nikulin, V / Nilsen, B S / Nilsson, M S / Noferini, F / Nomokonov, P / Nooren, G / Novitzky, N / Nyanin, A / Nyatha, A / Nygaard, C / Nystrand, J / Ochirov, A / Oeschler, H / Oh, S / Oh, S K / Oleniacz, J / Oppedisano, C / Ortiz Velasquez, A / Ortona, G / Oskarsson, A / Ostrowski, P / Otwinowski, J / Oyama, K / Ozawa, K / Pachmayer, Y / Pachr, M / Padilla, F / Pagano, P / Paić, G / Painke, F / Pajares, C / Pal, S K / Palaha, A / Palmeri, A / Papikyan, V / Pappalardo, G S / Park, W J / Passfeld, A / Pastirčák, B / Patalakha, D I / Paticchio, V / Pavlinov, A / Pawlak, T / Peitzmann, T / Pereira Da Costa, H / Pereira De Oliveira Filho, E / Peresunko, D / Pérez Lara, C E / Perez Lezama, E / Perini, D / Perrino, D / Peryt, W / Pesci, A / Peskov, V / Pestov, Y / Petráček, V / Petran, M / Petris, M / Petrov, P / Petrovici, M / Petta, C / Piano, S / Piccotti, A / Pikna, M / Pillot, P / Pinazza, O / Pinsky, L / Pitz, N / Piyarathna, D B / Planinic, M / Płoskoń, M / Pluta, J / Pocheptsov, T / Pochybova, S / Podesta-Lerma, P L M / Poghosyan, M G / Polák, K / Polichtchouk, B / Pop, A / Porteboeuf-Houssais, S / Pospíšil, V / Potukuchi, B / Prasad, S K / Preghenella, R / Prino, F / Pruneau, C A / Pshenichnov, I / Puchagin, S / Puddu, G / Pulvirenti, A / Punin, V / Putiš, M / Putschke, J / Quercigh, E / Qvigstad, H / Rachevski, A / Rademakers, A / Räihä, T S / Rak, J / Rakotozafindrabe, A / Ramello, L / Ramírez Reyes, A / Raniwala, S / Raniwala, R / Räsänen, S S / Rascanu, B T / Rathee, D / Read, K F / Real, J S / Redlich, K / Reichelt, P / Reicher, M / Renfordt, R / Reolon, A R / Reshetin, A / Rettig, F / Revol, J-P / Reygers, K / Riccati, L / Ricci, R A / Richert, T / Richter, M / Riedler, P / Riegler, W / Riggi, F / Rodrigues Fernandes Rabacal, B / Rodríguez Cahuantzi, M / Rodriguez Manso, A / Røed, K / Rohr, D / Röhrich, D / Romita, R / Ronchetti, F / Rosnet, P / Rossegger, S / Rossi, A / Roy, P / Roy, C / Rubio Montero, A J / Rui, R / Russo, R / Ryabinkin, E / Rybicki, A / Sadovsky, S / Šafařík, K / Sahoo, R / Sahu, P K / Saini, J / Sakaguchi, H / Sakai, S / Sakata, D / Salgado, C A / Salzwedel, J / Sambyal, S / Samsonov, V / Sanchez Castro, X / Šándor, L / Sandoval, A / Sano, M / Sano, S / Santo, R / Santoro, R / Sarkamo, J / Scapparone, E / Scarlassara, F / Scharenberg, R P / Schiaua, C / Schicker, R / Schmidt, C / Schmidt, H R / Schreiner, S / Schuchmann, S / Schukraft, J / Schutz, Y / Schwarz, K / Schweda, K / Scioli, G / Scomparin, E / Scott, R / Segato, G / Selyuzhenkov, I / Senyukov, S / Seo, J / Serci, S / Serradilla, E / Sevcenco, A / Shabetai, A / Shabratova, G / Shahoyan, R / Sharma, N / Sharma, S / Rohni, S / Shigaki, K / Shimomura, M / Shtejer, K / Sibiriak, Y / Siciliano, M / Sicking, E / Siddhanta, S / Siemiarczuk, T / Silvermyr, D / Silvestre, C / Simatovic, G / Simonetti, G / Singaraju, R / Singh, R / Singha, S / Singhal, V / Sinha, B C / Sinha, T / Sitar, B / Sitta, M / Skaali, T B / Skjerdal, K / Smakal, R / Smirnov, N / Snellings, R J M / Søgaard, C / Soltz, R / Son, H / Song, M / Song, J / Soos, C / Soramel, F / Sputowska, I / Spyropoulou-Stassinaki, M / Srivastava, B K / Stachel, J / Stan, I / Stefanek, G / Steinpreis, M / Stenlund, E / Steyn, G / Stiller, J H / Stocco, D / Stolpovskiy, M / Strabykin, K / Strmen, P / Suaide, A A P / Subieta Vásquez, M A / Sugitate, T / Suire, C / Sukhorukov, M / Sultanov, R / Šumbera, M / Susa, T / Symons, T J M / Szanto de Toledo, A / Szarka, I / Szczepankiewicz, A / Szostak, A / Szymański, M / Takahashi, J / Tapia Takaki, J D / Tauro, A / Tejeda Muñoz, G / Telesca, A / Terrevoli, C / Thäder, J / Thomas, D / Tieulent, R / Timmins, A R / Tlusty, D / Toia, A / Torii, H / Toscano, L / Trubnikov, V / Truesdale, D / Trzaska, W H / Tsuji, T / Tumkin, A / Turrisi, R / Tveter, T S / Ulery, J / Ullaland, K / Ulrich, J / Uras, A / Urbán, J / Urciuoli, G M / Usai, G L / Vajzer, M / Vala, M / Valencia Palomo, L / Vallero, S / Vande Vyvre, P / van Leeuwen, M / Vannucci, L / Vargas, A / Varma, R / Vasileiou, M / Vasiliev, A / Vechernin, V / Veldhoen, M / Venaruzzo, M / Vercellin, E / Vergara, S / Vernet, R / Verweij, M / Vickovic, L / Viesti, G / Vikhlyantsev, O / Vilakazi, Z / Villalobos Baillie, O / Vinogradov, Y / Vinogradov, A / Vinogradov, L / Virgili, T / Viyogi, Y P / Vodopyanov, A / Voloshin, S / Voloshin, K / Volpe, G / von Haller, B / Vranic, D / Øvrebekk, G / Vrláková, J / Vulpescu, B / Vyushin, A / Wagner, V / Wagner, B / Wan, R / Wang, M / Wang, D / Wang, Y / Watanabe, K / Weber, M / Wessels, J P / Westerhoff, U / Wiechula, J / Wikne, J / Wilde, M / Wilk, A / Wilk, G / Williams, M C S / Windelband, B / Xaplanteris Karampatsos, L / Yaldo, C G / Yamaguchi, Y / Yang, H / Yang, S / Yasnopolskiy, S / Yi, J / Yin, Z / Yoo, I-K / Yoon, J / Yu, W / Yuan, X / Yushmanov, I / Zaccolo, V / Zach, C / Zampolli, C / Zaporozhets, S / Zarochentsev, A / Závada, P / Zaviyalov, N / Zbroszczyk, H / Zelnicek, P / Zgura, I S / Zhalov, M / Zhang, X / Zhang, H / Zhou, D / Zhou, Y / Zhou, F / Zhu, J / Zhu, X / Zichichi, A / Zimmermann, A / Zinovjev, G / Zoccarato, Y / Zynovyev, M / Zyzak, M

    The European physical journal. C, Particles and fields

    2013  Volume 73, Issue 6, Page(s) 2456

    Abstract: ... at LHC energies were carried out with the ALICE detector. The fractions of diffractive processes ...

    Abstract Measurements of cross sections of inelastic and diffractive processes in proton-proton collisions at LHC energies were carried out with the ALICE detector. The fractions of diffractive processes in inelastic collisions were determined from a study of gaps in charged particle pseudorapidity distributions: for single diffraction (diffractive mass
    Language English
    Publishing date 2013-06-08
    Publishing country France
    Document type Journal Article
    ZDB-ID 1459069-4
    ISSN 1434-6052 ; 1434-6044
    ISSN (online) 1434-6052
    ISSN 1434-6044
    DOI 10.1140/epjc/s10052-013-2456-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Energy dependence of the transverse momentum distributions of charged particles in pp collisions measured by ALICE.

    Abelev, B / Adam, J / Adamová, D / Adare, A M / Aggarwal, M M / Aglieri Rinella, G / Agnello, M / Agocs, A G / Agostinelli, A / Ahammed, Z / Ahmad, N / Ahmad Masoodi, A / Ahmed, I / Ahn, S A / Ahn, S U / Aimo, I / Aiola, S / Ajaz, M / Akindinov, A /
    Aleksandrov, D / Alessandro, B / Alexandre, D / Alici, A / Alkin, A / Alme, J / Alt, T / Altini, V / Altinpinar, S / Altsybeev, I / Alves Garcia Prado, C / Andrei, C / Andronic, A / Anguelov, V / Anielski, J / Antičić, T / Antinori, F / Antonioli, P / Aphecetche, L / Appelshäuser, H / Arbor, N / Arcelli, S / Armesto, N / Arnaldi, R / Aronsson, T / Arsene, I C / Arslandok, M / Augustinus, A / Averbeck, R / Awes, T C / Äystö, J / Azmi, M D / Bach, M / Badalà, A / Baek, Y W / Bailhache, R / Bala, R / Baldisseri, A / Baltasar Dos Santos Pedrosa, F / Bán, J / Baral, R C / Barbera, R / Barile, F / Barnaföldi, G G / Barnby, L S / Barret, V / Bartke, J / Basile, M / Bastid, N / Basu, S / Bathen, B / Batigne, G / Batyunya, B / Batzing, P C / Baumann, C / Bearden, I G / Beck, H / Bedda, C / Behera, N K / Belikov, I / Bellini, F / Bellwied, R / Belmont-Moreno, E / Bencedi, G / Beole, S / Berceanu, I / Bercuci, A / Berdnikov, Y / Berenyi, D / Bergognon, A A E / Bertens, R A / Berzano, D / Betev, L / Bhasin, A / Bhati, A K / Bhom, J / Bianchi, L / Bianchi, N / Bianchin, C / Bielčík, J / Bielčíková, J / Bilandzic, A / Bjelogrlic, S / Blanco, F / Blau, D / Blume, C / Bock, F / Bogdanov, A / Bøggild, H / Bogolyubsky, M / Boldizsár, L / Bombara, M / Book, J / Borel, H / Borissov, A / Bornschein, J / Botje, M / Botta, E / Böttger, S / Braidot, E / Braun-Munzinger, P / Bregant, M / Breitner, T / Broker, T A / Browning, T A / Broz, M / Brun, R / Bruna, E / Bruno, G E / Budnikov, D / Buesching, H / Bufalino, S / Buncic, P / Busch, O / Buthelezi, Z / Caffarri, D / Cai, X / Caines, H / Caliva, A / Calvo Villar, E / Camerini, P / Canoa Roman, V / Cara Romeo, G / Carena, F / Carena, W / Carminati, F / Casanova Díaz, A / Castillo Castellanos, J / Casula, E A R / Catanescu, V / Cavicchioli, C / Ceballos Sanchez, C / Cepila, J / Cerello, P / Chang, B / Chapeland, S / Charvet, J L / Chattopadhyay, S / Cherney, M / Cheshkov, C / Cheynis, B / Chibante Barroso, V / Chinellato, D D / Chochula, P / Chojnacki, M / Choudhury, S / Christakoglou, P / Christensen, C H / Christiansen, P / Chujo, T / Chung, S U / Cicalo, C / Cifarelli, L / Cindolo, F / Cleymans, J / Colamaria, F / Colella, D / Collu, A / Colocci, M / Conesa Balbastre, G / Conesa Del Valle, Z / Connors, M E / Contin, G / Contreras, J G / Cormier, T M / Corrales Morales, Y / Cortese, P / Cortés Maldonado, I / Cosentino, M R / Costa, F / Crochet, P / Cruz Albino, R / Cuautle, E / Cunqueiro, L / Dainese, A / Dang, R / Danu, A / Das, K / Das, D / Das, I / Dash, A / Dash, S / De, S / Delagrange, H / Deloff, A / Dénes, E / Deppman, A / de Barros, G O V / De Caro, A / de Cataldo, G / de Cuveland, J / De Falco, A / De Gruttola, D / De Marco, N / De Pasquale, S / de Rooij, R / Diaz Corchero, M A / Dietel, T / Divià, R / Di Bari, D / Di Giglio, C / Di Liberto, S / Di Mauro, A / Di Nezza, P / Djuvsland, Ø / Dobrin, A / Dobrowolski, T / Dönigus, B / Dordic, O / Dubey, A K / Dubla, A / Ducroux, L / Dupieux, P / Dutta 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    The European physical journal. C, Particles and fields

    2013  Volume 73, Issue 12, Page(s) 2662

    Abstract: Differential cross sections of charged particles in inelastic pp collisions as a function ... ...

    Abstract Differential cross sections of charged particles in inelastic pp collisions as a function of
    Language English
    Publishing date 2013-12-06
    Publishing country France
    Document type Journal Article
    ZDB-ID 1459069-4
    ISSN 1434-6052 ; 1434-6044
    ISSN (online) 1434-6052
    ISSN 1434-6044
    DOI 10.1140/epjc/s10052-013-2662-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Midrapidity antiproton-to-proton ratio in pp collisons at sqrt[s]=0.9 and 7 TeV measured by the ALICE experiment.

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Ganti, M S / Garabatos, C / García Trapaga, C / Gebelein, J / Gemme, R / Germain, M / Gheata, A / Gheata, M / Ghidini, B / Ghosh, P / Giraudo, G / Giubellino, P / Gladysz-Dziadus, E / Glasow, R / Glässel, P / Glenn, A / Gómez Jiménez, R / González Santos, H / González-Trueba, L H / González-Zamora, P / Gorbunov, S / Gorbunov, Y / Gotovac, S / Gottschlag, H / Grabski, V / Grajcarek, R / Grelli, A / Grigoras, A / Grigoras, C / Grigoriev, V / Grigoryan, A / Grigoryan, S / Grinyov, B / Grion, N / Gros, P / Grosse-Oetringhaus, J F / Grossiord, J-Y / Grosso, R / Guber, F / Guernane, R / Guerra, C / Guerzoni, B / Gulbrandsen, K / Gulkanyan, H / Gunji, T / Gupta, A / Gupta, R / Gustafsson, H-A / Gutbrod, H / Haaland, O / Hadjidakis, C / Haiduc, M / Hamagaki, H / Hamar, G / Hamblen, J / Han, B H / Harris, J W / Hartig, M / Harutyunyan, A / Hasch, D / Hasegan, D / Hatzifotiadou, D / Hayrapetyan, A / Heide, M / Heinz, M / Helstrup, H / Herghelegiu, A / Hernández, C / Herrera Corral, G / Herrmann, N / Hetland, K F / Hicks, B / Hiei, A / Hille, P T / Hippolyte, B / Horaguchi, T / Hori, Y / Hristov, P / Hrivnácová, I / Hu, S / Huang, M / Huber, S / Humanic, T J / Hutter, D / Hwang, D S / Ichou, R / Ilkaev, R / Ilkiv, I / Inaba, M / Innocenti, P G / Ippolitov, M / Irfan, M / Ivan, C / Ivanov, A / Ivanov, M / Ivanov, V / Iwasaki, T / Jachołkowski, A / Jacobs, P / Jancurová, L / Jangal, S / Janik, R / Jena, C / Jena, S / Jirden, L / Jones, G T / Jones, P G / Jovanović, P / Jung, H / Jung, W / Jusko, A / Kaidalov, A B / Kalcher, S / Kalinák, P / Kalisky, M / Kalliokoski, T / Kalweit, A / Kamal, A / Kamermans, R / Kanaki, K / Kang, E / Kang, J H / Kapitan, J / Kaplin, V / Kapusta, S / Karavichev, O / Karavicheva, T / Karpechev, E / Kazantsev, A / Kebschull, U / Keidel, R / Khan, M M / Khan, S A / Khanzadeev, A / Kharlov, Y / Kikola, D / Kileng, B / Kim, D J / Kim, D S / Kim, D W / Kim, H N / Kim, J / Kim, J H / Kim, J S / Kim, M / Kim, S H / Kim, S / Kim, Y / Kirsch, S / Kisel, I / Kiselev, S / Kisiel, A / Klay, J L / Klein, J / Klein-Bösing, C / Kliemant, M / Klovning, A / Kluge, A / Knichel, M L / Kniege, S / Koch, K / Kolevatov, R / Kolojvari, A / Kondratiev, V / Kondratyeva, N / Konevskih, A / Kornaś, E / Kour, R / Kowalski, M / Kox, S / Kozlov, K / Kral, J / Králik, I / Kramer, F / Kraus, I / Kravcáková, A / Krawutschke, T / Krivda, M / Krumbhorn, D / Krus, M / Kryshen, E / Krzewicki, M / Kucheriaev, Y / Kuhn, C / Kuijer, P G / Kumar, L / Kumar, N / Kupczak, R / Kurashvili, P / Kurepin, A / Kurepin, A N / Kuryakin, A / Kushpil, S / Kushpil, V / Kutouski, M / Kvaerno, H / Kweon, M J / Kwon, Y / La Rocca, P / Lackner, F / Ladrón de Guevara, P / Lafage, V / Lal, C / Lara, C / Larsen, D T / Laurenti, G / Lazzeroni, C / Le Bornec, Y / Le Bris, N / Lee, H / Lee, K S / Lee, S C / Lefèvre, F / Lenhardt, M / Leistam, L / Lehnert, J / Lenti, V / León, H / León Monzón, I / León Vargas, H / Lévai, P / Li, X / Li, Y / Lietava, R / Lindal, S / Lindenstruth, V / Lippmann, C / Lisa, M A / Liu, L / Loginov, V / Lohn, S / Lopez, X / López Noriega, M / López-Ramírez, R / López Torres, E / Løvhøiden, G / Lozea Feijo Soares, A / Lu, S / Lunardon, M / Luparello, G / Luquin, L / Lutz, J-R / Ma, K / Ma, R / Madagodahettige-Don, D M / Maevskaya, A / Mager, M / Mahapatra, D P / Maire, A / Makhlyueva, I / Mal'kevich, D / Malaev, M / Malagalage, K J / Maldonado Cervantes, I / Malek, M / Malkiewicz, T / Malzacher, P / Mamonov, A / Manceau, L / Mangotra, L / Manko, V / Manso, F / Manzari, V / Mao, Y / Mares, J / Margagliotti, G V / Margotti, A / Marín, A / Martashvili, I / Martinengo, P / Martínez Hernández, M I / Martínez Davalos, A / Martínez García, G / Maruyama, Y / Marzari Chiesa, A / Masciocchi, S / Masera, M / Masetti, M / Masoni, A / Massacrier, L / Mastromarco, M / Mastroserio, A / Matthews, Z L / Matyja, A / Mayani, D / Mazza, G / Mazzoni, M A / Meddi, F / Menchaca-Rocha, A / Mendez Lorenzo, P / Meoni, M / Mercado Pérez, J / Mereu, P / Miake, Y / Michalon, A / Miftakhov, N / Milano, L / Milosevic, J / Minafra, F / Mischke, A / Miśkowiec, D / Mitu, C / Mizoguchi, K / Mlynarz, J / Mohanty, B / Molnar, L / Mondal, M M / Montaño Zetina, L / Monteno, M / Montes, E / Morando, M / Moretto, S / Morsch, A / Moukhanova, T / Muccifora, V / Mudnic, E / Muhuri, S / Müller, H / Munhoz, M G / Munoz, J / Musa, L / Musso, A / Nandi, B K / Nania, R / Nappi, E / Navach, F / Navin, S / Nayak, T K / Nazarenko, S / Nazarov, G / Nedosekin, A / Nendaz, F / Newby, J / Nianine, A / Nicassio, M / Nielsen, B S / Nikolaev, S / Nikolic, V / Nikulin, S / Nikulin, V / Nilsen, B S / Nilsson, M S / Noferini, F / Nomokonov, P / Nooren, G / Novitzky, N / Nyatha, A / Nygaard, C / Nyiri, A / Nystrand, J / Ochirov, A / Odyniec, G / Oeschler, H / Oinonen, M / Okada, K / Okada, Y / Oldenburg, M / Oleniacz, J / Oppedisano, C / Orsini, F / Ortiz Velasquez, A / Ortona, G / Oskarsson, A / Osmic, F / Osterman, L / Ostrowski, P / Otterlund, I / Otwinowski, J / Ovrebekk, G / Oyama, K / Ozawa, K / Pachmayer, Y / Pachr, M / Padilla, F / Pagano, P / Paić, G / Painke, F / Pajares, C / Pal, S / Pal, S K / Palaha, A / Palmeri, A / Panse, R / Papikyan, V / Pappalardo, G S / Park, W J / Pastircák, B / Pastore, C / Paticchio, V / Pavlinov, A / Pawlak, T / Peitzmann, T / Pepato, A / Pereira, H / Peressounko, D / Pérez, C / Perini, D / Perrino, D / Peryt, W / Peschek, J / Pesci, A / Peskov, V / Pestov, Y / Peters, A J / Petrácek, V / Petridis, A / Petris, M / Petrov, P / Petrovici, M / Petta, C / Peyré, J / Piano, S / Piccotti, A / Pikna, M / Pillot, P / Pinazza, O / Pinsky, L / Pitz, N / Piuz, F / Platt, R / Płoskoń, M / Pluta, J / Pocheptsov, T / Pochybova, S / Podesta Lerma, P L M / Poggio, F / Poghosyan, M G / Polák, K / Polichtchouk, B / Polozov, P / Polyakov, V / Pommeresch, B / Pop, A / Posa, F / Pospísil, V / Potukuchi, B / Pouthas, J / Prasad, S K / Preghenella, R / Prino, F / Pruneau, C A / Pshenichnov, I / Puddu, G / Pujahari, P / Pulvirenti, A / Punin, A / Punin, V / Putis, M / Putschke, J / Quercigh, E / Rachevski, A / Rademakers, A / Radomski, S / Räihä, T S / Rak, J / Rakotozafindrabe, A / Ramello, L / Ramírez Reyes, A / Rammler, M / Raniwala, R / Raniwala, S / Räsänen, S S / Rashevskaya, I / Rath, S / Read, K F / Real, J S / Redlich, K / Renfordt, R / Reolon, A R / Reshetin, A / Rettig, F / Revol, J-P / Reygers, K / Ricaud, H / Riccati, L / Ricci, R A / Richter, M / Riedler, P / Riegler, W / Riggi, F / Rivetti, A / Rodriguez Cahuantzi, M / Røed, K / Röhrich, D / Román López, S / Romita, R / Ronchetti, F / Rosinský, P / Rosnet, P / Rossegger, S / Rossi, A / Roukoutakis, F / Rousseau, S / Roy, C / Roy, P / Rubio-Montero, A J / Rui, R / Rusanov, I / Russo, G / Ryabinkin, E / Rybicki, A / Sadovsky, S / Safarík, K / Sahoo, R / Saini, J / Saiz, P / Sakata, D / Salgado, C A / Salgueiro Domingues da Silva, R / Salur, S / Samanta, T / Sambyal, S / Samsonov, V / Sándor, L / Sandoval, A / Sano, M / Sano, S / Santo, R / Santoro, R / Sarkamo, J / Saturnini, P / Scapparone, E / Scarlassara, F / Scharenberg, R P / Schiaua, C / Schicker, R / Schindler, H / Schmidt, C / Schmidt, H R / Schossmaier, K / Schreiner, S / Schuchmann, S / Schukraft, J / Schutz, Y / Schwarz, K / Schweda, K / Scioli, G / Scomparin, E / Scott, P A / Segato, G / Semenov, D / Senyukov, S / Seo, J / Serci, S / Serkin, L / Serradilla, E / Sevcenco, A / Sgura, I / Shabratova, G / Shahoyan, R / Sharkov, G / Sharma, N / Sharma, S / Shigaki, K / Shimomura, M / Shtejer, K / Sibiriak, Y / Siciliano, M / Sicking, E / Siddi, E / Siemiarczuk, T / Silenzi, A / Silvermyr, D / Simili, E / Simonetti, G / Singaraju, R / Singh, R / Singhal, V / Sinha, B C / Sinha, T / Sitar, B / Sitta, M / Skaali, T B / Skjerdal, K / Smakal, R / Smirnov, N / Snellings, R / Snow, H / Søgaard, C / Soloviev, A / Soltveit, H K / Soltz, R / Sommer, W / Son, C W / Son, H / Song, M / Soos, C / Soramel, F / Soyk, D / Spyropoulou-Stassinaki, M / Srivastava, B K / Stachel, J / Staley, F / Stan, E / Stefanek, G / Stefanini, G / Steinbeck, T / Stenlund, E / Steyn, G / Stocco, D / Stock, R / Stolpovsky, P / Strmen, P / Suaide, A A P / Subieta Vásquez, M A / Sugitate, T / Suire, C / Sumbera, M / Susa, T / Swoboda, D / Symons, J / Szanto de Toledo, A / Szarka, I / Szostak, A / Szuba, M / Tadel, M / Tagridis, C / Takahara, A / Takahashi, J / Tanabe, R / Tapia Takaki, J D / Taureg, H / Tauro, A / Tavlet, M / Tejeda Muñoz, G / Telesca, A / Terrevoli, C / Thäder, J / Tieulent, R / Tlusty, D / Toia, A / Tolyhy, T / Torcato de Matos, C / Torii, H / Torralba, G / Toscano, L / Tosello, F / Tournaire, A / Traczyk, T / Tribedy, P / Tröger, G / Truesdale, D / Trzaska, W H / Tsiledakis, G / Tsilis, E / Tsuji, T / Tumkin, A / Turrisi, R / Turvey, A / Tveter, T S / Tydesjö, H / Tywoniuk, K / Ulery, J / Ullaland, K / Uras, A / Urbán, J / Urciuoli, G M / Usai, G L / Vacchi, A / Vala, M / Valencia Palomo, L / Vallero, S / van der Kolk, N / Vande Vyvre, P / van Leeuwen, M / Vannucci, L / Vargas, A / Varma, R / Vasiliev, A / Vassiliev, I / Vasileiou, M / Vechernin, V / Venaruzzo, M / Vercellin, E / Vergara, S / Vernet, R / Verweij, M / Vetlitskiy, I / Vickovic, L / Viesti, G / Vikhlyantsev, O / Vilakazi, Z / Villalobos Baillie, O / Vinogradov, A / Vinogradov, L / Vinogradov, Y / Virgili, T / Viyogi, Y P / Vodopianov, A / Voloshin, K / Voloshin, S / Volpe, G / von Haller, B / Vranic, D / Vrláková, J / Vulpescu, B / Wagner, B / Wagner, V / Wallet, L / Wan, R / Wang, D / Wang, Y / Watanabe, K / Wen, Q / Wessels, J / Westerhoff, U / Wiechula, J / Wikne, J / Wilk, A / Wilk, G / Williams, M C S / Willis, N / Windelband, B / Xu, C / Yang, C / Yang, H / Yasnopolskiy, S / Yermia, F / Yi, J / Yin, Z / Yokoyama, H / Yoo, I-K / Yuan, X / Yurevich, V / Yushmanov, I / Zabrodin, E / Zagreev, B / Zalite, A / Zampolli, C / Zanevsky, Yu / Zaporozhets, S / Zarochentsev, A / Závada, P / Zbroszczyk, H / Zelnicek, P / Zenin, A / Zepeda, A / Zgura, I / Zhalov, M / Zhang, X / Zhou, D / Zhou, S / Zhu, J / Zichichi, A / Zinchenko, A / Zinovjev, G / Zoccarato, Y / Zychácek, V / Zynovyev, M

    Physical review letters

    2010  Volume 105, Issue 7, Page(s) 72002

    Abstract: The ratio of the yields of antiprotons to protons in pp collisions has been measured by the ALICE ...

    Abstract The ratio of the yields of antiprotons to protons in pp collisions has been measured by the ALICE experiment at sqrt[s]=0.9 and 7 TeV during the initial running periods of the Large Hadron Collider. The measurement covers the transverse momentum interval 0.45<p_{t}<1.05  GeV/c and rapidity |y|<0.5. The ratio is measured to be R_{|y|<0.5}=0.957±0.006(stat)±0.014(syst) at 0.9 TeV and R_{|y|<0.5}=0.991±0.005(stat)±0.014(syst) at 7 TeV and it is independent of both rapidity and transverse momentum. The results are consistent with the conventional model of baryon-number transport and set stringent limits on any additional contributions to baryon-number transfer over very large rapidity intervals in pp collisions.<br />
    Language English
    Publishing date 2010-08-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.105.072002
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  4. Article ; Online: Computational and experimental validation of phthalocyanine and hypericin as effective SARS-CoV-2 fusion inhibitors.

    Romeo, Alice / Cappelli, Giulia / Iacovelli, Federico / Colizzi, Vittorio / Falconi, Mattia

    Journal of biomolecular structure & dynamics

    2023  Volume 42, Issue 8, Page(s) 3920–3934

    Abstract: Phthalocyanine and hypericin have been previously identified as possible SARS-CoV-2 Spike glycoprotein fusion inhibitors through a virtual screening procedure. In this paper, atomistic simulations of metal-free phthalocyanines and atomistic and coarse- ... ...

    Abstract Phthalocyanine and hypericin have been previously identified as possible SARS-CoV-2 Spike glycoprotein fusion inhibitors through a virtual screening procedure. In this paper, atomistic simulations of metal-free phthalocyanines and atomistic and coarse-grained simulations of hypericins, placed around a complete model of the Spike embedded in a viral membrane, allowed to further explore their multi-target inhibitory potential, uncovering their binding to key protein functional regions and their propensity to insert in the membrane. Following computational results, pre-treatment of a pseudovirus expressing the SARS-CoV-2 Spike protein with low compounds concentrations resulted in a strong inhibition of its entry into cells, suggesting the activity of these molecules should involve the direct targeting of the viral envelope surface. The combination of computational and
    MeSH term(s) Perylene/analogs & derivatives ; Perylene/chemistry ; Perylene/pharmacology ; Anthracenes/chemistry ; Indoles/chemistry ; Indoles/pharmacology ; SARS-CoV-2/drug effects ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism ; Spike Glycoprotein, Coronavirus/antagonists & inhibitors ; Humans ; Isoindoles/chemistry ; Isoindoles/pharmacology ; Molecular Dynamics Simulation ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry ; Molecular Docking Simulation ; COVID-19 Drug Treatment ; Virus Internalization/drug effects ; Protein Binding ; COVID-19/virology
    Chemical Substances hypericin (7V2F1075HD) ; Perylene (5QD5427UN7) ; Anthracenes ; Indoles ; Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2 ; phthalocyanine (V5PUF4VLGY) ; Isoindoles ; Antiviral Agents
    Language English
    Publishing date 2023-05-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2216276
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  5. Article ; Online: Establishment of an Italian and a European Maxillofacial Surgery Interest Group.

    Iacoviello, Paolo / Da Rold, Mariano / Romeo, Antonella / Gramegna, Marco / Chiodi, Stefano / Mattioli, Beniamino / Mazzoni, Luca / Tavakkoli, Alice / Cardillo, Giovanni / Audino, Giovanni / Signorini, Giuseppe / Costanzo, Domenico

    The Journal of craniofacial surgery

    2024  

    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000010027
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  6. Article: The Relationship between Carcass Condemnations and Tail Lesion in Swine Considering Different Production Systems and Tail Lengths.

    Gomes, Alice / Romeo, Claudia / Ghidini, Sergio / Vieira-Pinto, Madalena

    Animals : an open access journal from MDPI

    2022  Volume 12, Issue 8

    Abstract: Tail biting has been recognised as an intractable problem in pig production. This study aims to evaluate tail lesion occurrence in slaughtered pigs and explore the relationship between carcass condemnations and tail lesion considering different ... ...

    Abstract Tail biting has been recognised as an intractable problem in pig production. This study aims to evaluate tail lesion occurrence in slaughtered pigs and explore the relationship between carcass condemnations and tail lesion considering different production systems and tail lengths and to evaluate the importance of creating a detailed tail score classification that includes scarred lesions. Data on a total of 9189 pigs from 73 batches with different tail lengths (undocked; docked mid-length; fully docked) and from distinct production systems (conventional; conventional antibiotic-free and organic) were collected at a Spanish abattoir. Batches with higher tail lesion scores presented a significantly higher chance of total condemnation and total condemnation due to pyaemia, being even more associated with scarring score. The within-batches probability for local condemnations and local condemnation due to abscesses increased significantly with higher scarring scores. Regarding tail length, docked at mid-length and undocked carcasses presented significantly higher odds to be condemned due to abscess. Organic farms showed a higher probability of total condemnations. This research highlights the importance of tail lesions on carcass condemnations that may also be influenced by docking and type of production. Results suggest that scarring score should be included in the tail surveillance program.
    Language English
    Publishing date 2022-04-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani12080949
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  7. Article: Up right, not right up: Primacy of verticality in both language and movement.

    Boulenger, Véronique / Finos, Livio / Koun, Eric / Salemme, Roméo / Desoche, Clément / Roy, Alice C

    Frontiers in human neuroscience

    2022  Volume 16, Page(s) 981330

    Abstract: When describing motion along both the horizontal and vertical axes, languages from different families express the elements encoding verticality before those coding for horizontality (e.g., ...

    Abstract When describing motion along both the horizontal and vertical axes, languages from different families express the elements encoding verticality before those coding for horizontality (e.g.,
    Language English
    Publishing date 2022-09-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2425477-0
    ISSN 1662-5161
    ISSN 1662-5161
    DOI 10.3389/fnhum.2022.981330
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  8. Article ; Online: Reconstructing the Free Energy Profiles Describing the Switching Mechanism of a pH-Dependent DNA Nanodevice from ABMD Simulations

    Alice Romeo / Mattia Falconi / Alessandro Desideri / Federico Iacovelli

    Applied Sciences, Vol 11, Iss 4052, p

    2021  Volume 4052

    Abstract: The pH-responsive behavior of six triple-helix DNA nanoswitches, differing in the number of protonation centers (two or four) and in the length of the linker (5, 15 or 25 bases), connecting the double-helical region to the single-strand triplex-forming ... ...

    Abstract The pH-responsive behavior of six triple-helix DNA nanoswitches, differing in the number of protonation centers (two or four) and in the length of the linker (5, 15 or 25 bases), connecting the double-helical region to the single-strand triplex-forming region, was characterized at the atomistic level through Adaptively Biased Molecular Dynamics simulations. The reconstruction of the free energy profiles of triplex-forming oligonucleotide unbinding from the double helix identified a different minimum energy path for the three diprotic nanoswitches, depending on the length of the connecting linker and leading to a different per-base unbinding profile. The same analyses carried out on the tetraprotic switches indicated that, in the presence of four protonation centers, the unbinding process occurs independently of the linker length. The simulation data provide an atomistic explanation for previously published experimental results showing, only in the diprotic switch, a two unit increase in the pKa switching mechanism decreasing the linker length from 25 to 5 bases, endorsing the validity of computational methods for the design and refinement of functional DNA nanodevices.
    Keywords DNA nanoswitch ; ABMD simulations ; free energy profiles ; DNA triple helix ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 612
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Targeting the SARS-CoV-2 spike glycoprotein prefusion conformation: virtual screening and molecular dynamics simulations applied to the identification of potential fusion inhibitors.

    Romeo, Alice / Iacovelli, Federico / Falconi, Mattia

    Virus research

    2020  Volume 286, Page(s) 198068

    Abstract: The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a renewed interest in studying the role of the spike S glycoprotein in regulating coronavirus infections in the natural host. Taking advantage of the cryo- ... ...

    Abstract The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a renewed interest in studying the role of the spike S glycoprotein in regulating coronavirus infections in the natural host. Taking advantage of the cryo-electron microscopy structure of SARS-CoV-2 S trimer in the prefusion conformation, we performed a virtual screening simulation with the aim to identify novel molecules that could be used as fusion inhibitors. The spike glycoprotein structure has been completed using modeling techniques and its inner cavity, needful for the postfusion transition of the trimer, has been scanned for the identification of strongly interacting available drugs. Finally, the stability of the protein-drug top complexes has been tested using classical molecular dynamics simulations. The free energy of interaction of the molecules to the spike protein has been evaluated through the MM/GBSA method and per-residue decomposition analysis. Results have been critically discussed considering previous scientific knowledge concerning the selected compounds and sequence alignments have been carried out to evaluate the spike glycoprotein similarity among the betacoronavirus family members. Finally, a cocktail of drugs that may be used as SARS-CoV-2 fusion inhibitors has been suggested.
    MeSH term(s) Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Betacoronavirus/chemistry ; Betacoronavirus/pathogenicity ; Binding Sites ; COVID-19 ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Gene Expression ; Heterocyclic Compounds, 4 or More Rings/chemistry ; Heterocyclic Compounds, 4 or More Rings/pharmacology ; High-Throughput Screening Assays ; Humans ; Indoles/chemistry ; Indoles/pharmacology ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Pandemics ; Perylene/analogs & derivatives ; Perylene/chemistry ; Perylene/pharmacology ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/virology ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Protein Multimerization ; SARS-CoV-2 ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Spike Glycoprotein, Coronavirus/antagonists & inhibitors ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Sulfonamides/chemistry ; Sulfonamides/pharmacology ; Thermodynamics ; User-Computer Interface ; Virus Internalization/drug effects
    Chemical Substances 27-cyclohexyl-12,13,16,17-tetrahydro-22-methoxy-11,17-dimethyl-10,10-dioxide-2,19-methano-3,7:4,1-dimetheno-1H,11H-14,10,2,9,11,17-benzoxathiatetraazacyclo docosine-8,18(9H,15H)-dione ; Antiviral Agents ; Heterocyclic Compounds, 4 or More Rings ; Indoles ; Small Molecule Libraries ; Spike Glycoprotein, Coronavirus ; Sulfonamides ; spike protein, SARS-CoV-2 ; Perylene (5QD5427UN7) ; hypericin (7V2F1075HD) ; phthalocyanine (V5PUF4VLGY)
    Keywords covid19
    Language English
    Publishing date 2020-06-18
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605780-9
    ISSN 1872-7492 ; 0168-1702
    ISSN (online) 1872-7492
    ISSN 0168-1702
    DOI 10.1016/j.virusres.2020.198068
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  10. Article: Targeting the SARS-CoV-2 spike glycoprotein prefusion conformation: virtual screening and molecular dynamics simulations applied to the identification of potential fusion inhibitors

    Romeo, Alice / Iacovelli, Federico / Falconi, Mattia

    Virus research. 2020 Sept., v. 286

    2020  

    Abstract: The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a renewed interest in studying the role of the spike S glycoprotein in regulating coronavirus infections in the natural host. Taking advantage of the cryo- ... ...

    Abstract The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a renewed interest in studying the role of the spike S glycoprotein in regulating coronavirus infections in the natural host. Taking advantage of the cryo-electron microscopy structure of SARS-CoV-2 S trimer in the prefusion conformation, we performed a virtual screening simulation with the aim to identify novel molecules that could be used as fusion inhibitors. The spike glycoprotein structure has been completed using modeling techniques and its inner cavity, needful for the postfusion transition of the trimer, has been scanned for the identification of strongly interacting available drugs. Finally, the stability of the protein-drug top complexes has been tested using classical molecular dynamics simulations. The free energy of interaction of the molecules to the spike protein has been evaluated through the MM/GBSA method and per-residue decomposition analysis. Results have been critically discussed considering previous scientific knowledge concerning the selected compounds and sequence alignments have been carried out to evaluate the spike glycoprotein similarity among the betacoronavirus family members. Finally, a cocktail of drugs that may be used as SARS-CoV-2 fusion inhibitors has been suggested.
    Keywords Coronavirus infections ; Gibbs free energy ; Severe acute respiratory syndrome coronavirus 2 ; cryo-electron microscopy ; drugs ; glycoproteins ; molecular dynamics ; screening ; sequence alignment ; simulation models
    Language English
    Dates of publication 2020-09
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 605780-9
    ISSN 1872-7492 ; 0168-1702
    ISSN (online) 1872-7492
    ISSN 0168-1702
    DOI 10.1016/j.virusres.2020.198068
    Database NAL-Catalogue (AGRICOLA)

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