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  1. Book ; Online: Perspectives in Zebrafish Research

    Caterina Mione, Maria / Blader, Patrick / Del Bene, Filippo / Trompouki, Eirini / Henry Bianco, Isaac / Henry Bianco, Isaac

    2020  

    Keywords Science: general issues ; Biology, life sciences ; zebrafish ; development ; disease models ; neuroscience ; imaging tools ; genetic and genomics ; epigenetic ; cardiovascular ; hematopoietic
    Size 1 electronic resource (142 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230756
    ISBN 9782889636693 ; 2889636690
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Adherence with infection prevention and control measures among Italian healthcare workers

    Francesca Licata / Caterina Viscomi / Silvia Angelillo / Gianfranco Di Gennaro / Aida Bianco

    Journal of Infection and Public Health, Vol 17, Iss 1, Pp 122-

    Lessons from the COVID-19 pandemic to tackle future ones

    2024  Volume 129

    Abstract: Background: To tackle future health threats, the study aimed to assess healthcare workers’ (HCWs) adherence to infection prevention and control (IPC) measures and to evaluate whether knowledge and concerns related to COVID-19 could be its potential ... ...

    Abstract Background: To tackle future health threats, the study aimed to assess healthcare workers’ (HCWs) adherence to infection prevention and control (IPC) measures and to evaluate whether knowledge and concerns related to COVID-19 could be its potential predictors. A secondary aim was to explore how and how much healthcare facilities support HCWs to implement IPC practices. Methods: This cross-sectional study was conducted between June and September 2021 in Southern Italy using a self-administered questionnaire. Socio-demographic and professional characteristics, COVID-19 preparedness and response plan in the facilities, knowledge about COVID-19’s transmission and non-pharmaceutical interventions (NPIs), concerns about the possibility of transmitting COVID-19 to family members and patients, adherence to IPC practices, and sources of information were investigated. Results: Among the 492 enrolled HCWs, the overall knowledge median score was 6 out of a maximum score of 8 and predictors of good knowledge were practicing in a facility that organized training courses about IPC measures and having more years in practice. HCWs were more concerned about the possibility of transmitting the infection to their family members (64.4%) than to negative patients (38.9%). A sizable proportion claimed to take off the face mask by touching only the straps or ties (76.3%) and to replace the face mask when it was wet (70.7%). Only 26.2% never/rarely touched the face mask while wearing it. Good adherence to preventative practices was more likely in HCWs other than physicians and practicing in a facility that organized training courses about IPC measures and in regional hospitals compared with those practicing in district hospitals. Conclusions: The study findings produce information about what worked well and where gaps were identified during COVID-19 pandemic, along with data useful for hospitals and health systems in general to better prepare and put in place appropriate interventions in case of similar future events.
    Keywords Adherence ; Healthcare workers ; Health threat ; Hospitals ; Infection prevention and control ; Italy ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: The predictive role of intolerance of uncertainty and trait of worry in breast cancer patients: A prospective, observational, single-center clinical study.

    Shams, Malihe / Pardini, Susanna / Del Bianco, Paola / Calabrese, Caterina / De Salvo, Gian Luca / Novara, Caterina

    Frontiers in psychology

    2023  Volume 14, Page(s) 1092060

    Abstract: Background: Breast cancer diagnosis and treatment compromise well-being in a pervasive way, and negative consequences may remain after recovery. The psychological side of breast cancer has been extensively investigated; however, the role of intrusive ... ...

    Abstract Background: Breast cancer diagnosis and treatment compromise well-being in a pervasive way, and negative consequences may remain after recovery. The psychological side of breast cancer has been extensively investigated; however, the role of intrusive thoughts and intolerance of uncertainty have been studied less systematically.
    Objectives: The present study aimed to prospectively evaluate worry content, depression, anxiety, and post-traumatic stress symptoms and to define the role of the trait of worry and intolerance of uncertainty (IU) related to breast cancer.
    Methods: Patients with their first breast cancer diagnosis were enrolled in a single-center, prospective observational trial. The trait of worry and IU were assessed using the Penn State Worry Questionnaire (PSWQ) and the Intolerance of Uncertainty Scale-Revised (IUS-R). The psychological aspects were evaluated using the Worry Domains Questionnaire (WDQ), the Beck Anxiety (BAI), Beck Depression Inventory-II (BDI-II), and the Impact of Event Scale-Revised (IES-R). Questionnaires were administered in a randomized sequence at diagnosis (T0), 3 months post-diagnosis (T1), and 12 months post-diagnosis (T2).
    Results: One hundred and fifty eligible patients were enrolled in the study and provided the T0 assessment. Further compliance rates were 57% at T1 and 64% at T2. All patients showed a significant and continuous increase in the IES-R scale (
    Conclusion: An early assessment of the components of the trait of worry and intolerance of uncertainty could be critical in identifying patients with a higher psychopathological risk. Furthermore, if future studies confirm the present findings, support and monitoring throughout the prognosis may present crucial benefits, and possibly affect the course of treatment.
    Language English
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1092060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Development and Internal Validation of a Model for Predicting Overall Survival in Subjects with MAFLD: A Cohort Study.

    Bonfiglio, Caterina / Campanella, Angelo / Donghia, Rossella / Bianco, Antonella / Franco, Isabella / Curci, Ritanna / Bagnato, Claudia Beatrice / Tatoli, Rossella / Giannelli, Gianluigi / Cuccaro, Francesco

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: Background & ... ...

    Abstract Background & Aims
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13041181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Adherence with infection prevention and control measures among Italian healthcare workers: Lessons from the COVID-19 pandemic to tackle future ones.

    Licata, Francesca / Viscomi, Caterina / Angelillo, Silvia / Di Gennaro, Gianfranco / Bianco, Aida

    Journal of infection and public health

    2023  Volume 17, Issue 1, Page(s) 122–129

    Abstract: Background: To tackle future health threats, the study aimed to assess healthcare workers' (HCWs) adherence to infection prevention and control (IPC) measures and to evaluate whether knowledge and concerns related to COVID-19 could be its potential ... ...

    Abstract Background: To tackle future health threats, the study aimed to assess healthcare workers' (HCWs) adherence to infection prevention and control (IPC) measures and to evaluate whether knowledge and concerns related to COVID-19 could be its potential predictors. A secondary aim was to explore how and how much healthcare facilities support HCWs to implement IPC practices.
    Methods: This cross-sectional study was conducted between June and September 2021 in Southern Italy using a self-administered questionnaire. Socio-demographic and professional characteristics, COVID-19 preparedness and response plan in the facilities, knowledge about COVID-19's transmission and non-pharmaceutical interventions (NPIs), concerns about the possibility of transmitting COVID-19 to family members and patients, adherence to IPC practices, and sources of information were investigated.
    Results: Among the 492 enrolled HCWs, the overall knowledge median score was 6 out of a maximum score of 8 and predictors of good knowledge were practicing in a facility that organized training courses about IPC measures and having more years in practice. HCWs were more concerned about the possibility of transmitting the infection to their family members (64.4%) than to negative patients (38.9%). A sizable proportion claimed to take off the face mask by touching only the straps or ties (76.3%) and to replace the face mask when it was wet (70.7%). Only 26.2% never/rarely touched the face mask while wearing it. Good adherence to preventative practices was more likely in HCWs other than physicians and practicing in a facility that organized training courses about IPC measures and in regional hospitals compared with those practicing in district hospitals.
    Conclusions: The study findings produce information about what worked well and where gaps were identified during COVID-19 pandemic, along with data useful for hospitals and health systems in general to better prepare and put in place appropriate interventions in case of similar future events.
    MeSH term(s) Humans ; COVID-19/prevention & control ; COVID-19/epidemiology ; Cross-Sectional Studies ; Pandemics/prevention & control ; Health Knowledge, Attitudes, Practice ; Health Personnel ; Italy/epidemiology ; Infection Control
    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2023.10.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reply to Cetkovic et al. Comment on "Meneghini et al. The Impact of Nutritional Therapy in the Management of Overweight/Obese PCOS Patient Candidates for IVF.

    Meneghini, Caterina / Bianco, Claudia / Galanti, Francesco / Tamburelli, Valentina / Dal Lago, Alessandro / Licata, Emanuele / Gallo, Mariagrazia / Fabiani, Cristina / Corno, Roberta / Miriello, Donatella / Rago, Rocco

    Nutrients

    2024  Volume 16, Issue 3

    Abstract: Thanks for your comment [ ... ]. ...

    Abstract Thanks for your comment [...].
    MeSH term(s) Female ; Humans ; Overweight/complications ; Overweight/therapy ; Polycystic Ovary Syndrome/complications ; Polycystic Ovary Syndrome/therapy ; Obesity/complications ; Obesity/therapy ; Nutrients ; Fertilization in Vitro
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16030439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Cholangiocyte Organoids: The New Frontier in Regenerative Medicine for the Study and Treatment of Cholangiopathies.

    Babboni, Serena / Vacca, Pier Giuseppe / Simonini, Ludovica / Pezzati, Daniele / Martinelli, Caterina / Frongillo, Francesco / Bianco, Giuseppe / Marciano, Emanuele / Basta, Giuseppina / Ghinolfi, Davide / Del Turco, Serena

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: Cholangiopathies include a group of chronic progressive disorders, affecting the cholangiocytes, the epithelial cells that line the biliary tree, leading to liver parenchymal fibrosis and eventually end-stage liver disease necessitating transplantation. ... ...

    Abstract Cholangiopathies include a group of chronic progressive disorders, affecting the cholangiocytes, the epithelial cells that line the biliary tree, leading to liver parenchymal fibrosis and eventually end-stage liver disease necessitating transplantation. Experimental modeling of these multifactorial cholestatic diseases faces challenges due to the lack of adequate experimental in vitro and in vivo models. A novel approach employs three-dimensional organoid systems that offer several advantages for modeling disease and testing drug response in vitro. Organoids mimic intercellular communication, replicate the architecture of organs, and maintain the cell's original phenotype. Cholangiocyte organoids provide an in vitro model to study the pathogenesis and pharmacotherapeutic treatment of cholangiopathies and show great promise for regenerative therapies. In particular, patient-derived organoids allow personalized medicine approaches and the study of individual disease characteristics. This review highlights the significance of cholangiocyte organoid models in advancing our understanding of cholangiopathies and driving advancements in regenerative medicine strategies.
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Total mesorectal excision laparoscopic versus transanal approach for rectal cancer: A systematic review and meta-analysis.

    Lo Bianco, Salvatore / Lanzafame, Katia / Piazza, Caterina Domenica / Piazza, Vincenzo Gaetano / Provenzano, Daniele / Piazza, Diego

    Annals of medicine and surgery (2012)

    2022  Volume 74, Page(s) 103260

    Abstract: Introduction: Total mesorectal excision (TME) performed for the first time by Held through an open approach, it has become the standard technique for the surgical treatment of rectal cancer. The aim the of this meta-analysis is to compare the outcomes ... ...

    Abstract Introduction: Total mesorectal excision (TME) performed for the first time by Held through an open approach, it has become the standard technique for the surgical treatment of rectal cancer. The aim the of this meta-analysis is to compare the outcomes provided by TaTME than LaTME.
    Material and methods: In this meta-analysis, we included all comparative studies, prospective and retrospective, which addressed in low and middle rectal cancer, a comparison between TaTME and LaTME. A search was performed through MEDLINE and Cochrane Database. 846 records were identified.
    Results: Eight relevant studies have been included in this meta-analysis. The studies were from France, Russia, USA, Netherlands, Taiwan, Egypt. The eight studies including 471 patients with middle or low rectal cancer.
    Conclusion: The meta-analysis confirmed safety of TaTME for low and middle rectal cancer. TaTME can lead to a high quality of rectal cancer resection specimen.
    Language English
    Publishing date 2022-01-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2022.103260
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Sunset Yellow Confined in Curved Geometry: A Microfluidic Approach.

    Tone, Caterina Maria / Zizzari, Alessandra / Spina, Lorenza / Bianco, Monica / De Santo, Maria Penelope / Arima, Valentina / Barberi, Riccardo Cristoforo / Ciuchi, Federica

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 17, Page(s) 6134–6141

    Abstract: The behavior of lyotropic chromonic liquid crystals (LCLCs) in confined environments is an interesting research field that still awaits exploration, with multiple key variables to be uncovered and understood. Microfluidics is a highly versatile technique ...

    Abstract The behavior of lyotropic chromonic liquid crystals (LCLCs) in confined environments is an interesting research field that still awaits exploration, with multiple key variables to be uncovered and understood. Microfluidics is a highly versatile technique that allows us to confine LCLCs in micrometric spheres. As microscale networks offer distinct interplays between the surface effects, geometric confinement, and viscosity parameters, rich and unique interactions emerging at the LCLC-microfluidic channel interfaces are expected. Here, we report on the behavior of pure and chiral doped nematic Sunset Yellow (SSY) chromonic microdroplets produced through a microfluidic flow-focusing device. The continuous production of SSY microdroplets with controllable size gives the possibility to systematically study their topological textures as the function of their diameters. Indeed, doped SSY microdroplets produced via microfluidics, show topologies that are typical of common chiral thermotropic liquid crystals. Furthermore, few droplets exhibit a peculiar texture never observed for chiral chromonic liquid crystals. Finally, the achieved precise control of the produced LCLC microdroplets is a crucial step for technological applications in biosensing and anticounterfeiting.
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c00275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles.

    Caremani, Marco / Marcello, Matteo / Morotti, Ilaria / Pertici, Irene / Squarci, Caterina / Reconditi, Massimo / Bianco, Pasquale / Piazzesi, Gabriella / Lombardi, Vincenzo / Linari, Marco

    Communications biology

    2022  Volume 5, Issue 1, Page(s) 1266

    Abstract: Contraction of striated muscle is regulated by a dual mechanism involving both thin, actin-containing filament and thick, myosin-containing filament. Thin filament is activated by ... ...

    Abstract Contraction of striated muscle is regulated by a dual mechanism involving both thin, actin-containing filament and thick, myosin-containing filament. Thin filament is activated by Ca
    MeSH term(s) Animals ; Rabbits ; Sarcomeres/metabolism ; Actins/metabolism ; Muscle Contraction/physiology ; Calcium/metabolism ; Myosins/metabolism ; Muscle, Skeletal/metabolism
    Chemical Substances Actins ; Calcium (SY7Q814VUP) ; Myosins (EC 3.6.4.1)
    Language English
    Publishing date 2022-11-18
    Publishing country England
    Document type Journal Article
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-022-04184-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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