LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 204

Search options

  1. Book: Acute myeloid leukaemia

    Burnett, Alan K.

    (Best practice & research clinical haematology ; 14,1)

    2001  

    Author's details A. K. Burnett, guest ed
    Series title Best practice & research clinical haematology ; 14,1
    Best practice & research
    Collection Best practice & research
    Language English
    Size VII, 233, i8 S. : Ill., graph. Darst.
    Publisher Baillière Tindall
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013016282
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 1029 -14,1- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Modern management of acute myeloid leukemia

    Burnett, Alan K.

    (Seminars in hematology ; 38,3, Suppl. 6)

    2001  

    Author's details Alan K. Burnett, guest ed
    Series title Seminars in hematology ; 38,3, Suppl. 6
    Collection
    Language English
    Size 31 S.
    Publisher Saunders
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book
    HBZ-ID HT013135417
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 328 -38,Suppl.6- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Treatment of Older Patients With Newly Diagnosed AML Unfit for Traditional Therapy.

    Burnett, Alan K

    Clinical lymphoma, myeloma & leukemia

    2018  Volume 18, Issue 9, Page(s) 553–557

    Abstract: Older patients with acute myeloid leukemia represent at least one half of those with the disease for whom randomized clinical trials of new treatments are in development. These patients represent an appropriate population in which to evaluate new ... ...

    Abstract Older patients with acute myeloid leukemia represent at least one half of those with the disease for whom randomized clinical trials of new treatments are in development. These patients represent an appropriate population in which to evaluate new treatments against the current standards of care, which could be azacitidine, decitabine, or low-dose cytarabine. However, despite the identification of treatments that can deliver a worthwhile increase in remission, none has yet delivered a survival superiority when assessed in a randomized setting, although some recent efforts provide encouragement.
    MeSH term(s) Aged ; Antineoplastic Combined Chemotherapy Protocols/standards ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Remission Induction
    Language English
    Publishing date 2018-06-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2540992-X
    ISSN 2152-2669 ; 2152-2650
    ISSN (online) 2152-2669
    ISSN 2152-2650
    DOI 10.1016/j.clml.2018.06.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5903: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Gemtuzumab ozogamicin in (KMT2A)-rearranged adult acute myeloid leukaemia (AML) in the UK Medical Research Council AML15 and AML16 trials.

    Dillon, Richard / Hills, Robert K / Burnett, Alan K / Russell, Nigel H

    British journal of haematology

    2021  Volume 196, Issue 5, Page(s) e50–e52

    MeSH term(s) Adult ; Antineoplastic Agents, Immunological/therapeutic use ; Gemtuzumab/therapeutic use ; Gene Rearrangement/drug effects ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/epidemiology ; Leukemia, Myeloid, Acute/genetics ; Middle Aged ; Myeloid-Lymphoid Leukemia Protein/genetics ; Survival Analysis ; United Kingdom/epidemiology ; Young Adult
    Chemical Substances Antineoplastic Agents, Immunological ; KMT2A protein, human ; Myeloid-Lymphoid Leukemia Protein (149025-06-9) ; Gemtuzumab (93NS566KF7) ; Histone-Lysine N-Methyltransferase (EC 2.1.1.43)
    Language English
    Publishing date 2021-11-19
    Publishing country England
    Document type Clinical Trial ; Letter ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.17943
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.182: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Twenty five years of UK trials in acute myeloid leukaemia: what have we learned?

    Burnett, Alan K / Hills, Robert K / Russell, Nigel

    British journal of haematology

    2019  Volume 188, Issue 1, Page(s) 86–100

    MeSH term(s) Aged ; Clinical Trials as Topic/history ; Female ; History, 20th Century ; History, 21st Century ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/history ; Male ; United Kingdom
    Language English
    Publishing date 2019-12-11
    Publishing country England
    Document type Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.16359
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.182: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Therapy for isocitrate dehydrogenase 2 (IDH2)

    Linch, David C / Hills, Robert K / Burnett, Alan K / Russell, Nigel / Gale, Rosemary E

    British journal of haematology

    2021  Volume 196, Issue 6, Page(s) 1348–1352

    Abstract: Although we earlier reported a very poor outcome for younger adult patients with isocitrate dehydrogenase 2 (IDH2) ...

    Abstract Although we earlier reported a very poor outcome for younger adult patients with isocitrate dehydrogenase 2 (IDH2)
    MeSH term(s) Adult ; Cohort Studies ; Humans ; Isocitrate Dehydrogenase/genetics ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/therapy ; Mutation ; Prognosis
    Chemical Substances Isocitrate Dehydrogenase (EC 1.1.1.41)
    Language English
    Publishing date 2021-12-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.17981
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.182: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Treatment of acute myeloid leukaemia.

    Burnett, Alan K

    Clinical medicine (London, England)

    2013  Volume 13 Suppl 6, Page(s) s58–61

    Abstract: Acute myeloid leukaemia is a heterogeneous disease that occurs in all age groups but peaks in older age at around a median of 69-70 years where it has a frequency of 13-15/100,00/annum. With the changing demographics, the number of cases will increase in ...

    Abstract Acute myeloid leukaemia is a heterogeneous disease that occurs in all age groups but peaks in older age at around a median of 69-70 years where it has a frequency of 13-15/100,00/annum. With the changing demographics, the number of cases will increase in line with the older population. As the only treatment with curative intent is intensive chemotherapy, this presents an immediate therapeutic challenge for the majority of the disease.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Humans ; Leukemia, Myeloid, Acute ; Remission Induction ; Treatment Outcome
    Language English
    Publishing date 2013-12-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmedicine.13-6-s58
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5439: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: The clinical impact of mutant DNMT3A R882 variant allele frequency in acute myeloid leukaemia.

    Linch, David C / Hills, Robert K / Burnett, Alan K / Gale, Rosemary E

    British journal of haematology

    2020  Volume 189, Issue 3, Page(s) e81–e86

    MeSH term(s) Adolescent ; Adult ; Aged ; Alleles ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; Female ; Gene Frequency ; Humans ; Leukemia, Myeloid, Acute/enzymology ; Leukemia, Myeloid, Acute/genetics ; Male ; Middle Aged ; Mutation ; Young Adult
    Chemical Substances DNA (Cytosine-5-)-Methyltransferases (EC 2.1.1.37) ; DNA methyltransferase 3A (EC 2.1.1.37)
    Language English
    Publishing date 2020-01-31
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.16486
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.182: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: The Challenge of AML in Older Patients.

    Burnett, Alan K

    Mediterranean journal of hematology and infectious diseases

    2013  Volume 5, Issue 1, Page(s) e2013038

    Abstract: There has been a gradual improvement in the outcome for younger patients with Acute Myeloid Leukaemia over the last two decades, but unfortunately this same progress is not apparent in older patients. "Old" has come to mean rather arbitrarily, patients ... ...

    Abstract There has been a gradual improvement in the outcome for younger patients with Acute Myeloid Leukaemia over the last two decades, but unfortunately this same progress is not apparent in older patients. "Old" has come to mean rather arbitrarily, patients over 60 years. This age cut off has been perpetuated by clinical trials whose eligibility is frequently at this cut point. Age is a continuous variable right through all age groups with AML and has independent prognostic significance. Chemo-resistance of the disease itself is part of the explanation, with a high frequency of adverse biology occurring at older age. Patient characteristics which compromise the delivery of treatment of adequate intensity are the other important influence. Medical co-morbidities are more frequent, and when combined with what is sometimes referred to as limited haematopoietic reserve, undoubtedly make successful delivery of intensive therapy less likely. The outstanding problem for older patients is that remission is usually not durable, and there has been little improvement in overall survival for the last three decades, then new approaches need.
    Language English
    Publishing date 2013-06-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2674750-9
    ISSN 2035-3006
    ISSN 2035-3006
    DOI 10.4084/MJHID.2013.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Additional impact of mutational genotype on prognostic determination in resistant and relapsed acute myeloid leukaemia.

    Linch, David C / Hills, Robert K / Gilkes, Amanda / Burnett, Alan K / Russell, Nigel / Gale, Rosemary E

    Leukemia research

    2021  Volume 108, Page(s) 106553

    Abstract: Outcome after failure of initial therapy in younger adult patients with acute myeloid leukaemia (AML) is highly variable. Cytogenetics, length of first remission (CR1) before relapse, and allogeneic transplantation are known prognostic factors, but the ... ...

    Abstract Outcome after failure of initial therapy in younger adult patients with acute myeloid leukaemia (AML) is highly variable. Cytogenetics, length of first remission (CR1) before relapse, and allogeneic transplantation are known prognostic factors, but the contribution of leukaemic genotype is less clear, particularly in resistant disease. Of 5,651 younger adult patients entered into UK MRC/NCRI AML trials between 1988 and 2014 with available FLT3
    MeSH term(s) Adolescent ; Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biomarkers, Tumor/genetics ; Cytogenetic Analysis ; Drug Resistance, Neoplasm/genetics ; Female ; Follow-Up Studies ; Genotype ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Male ; Middle Aged ; Mutation ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Nucleophosmin ; Prognosis ; Retrospective Studies ; Survival Rate ; Young Adult
    Chemical Substances Biomarkers, Tumor ; NPM1 protein, human ; Nucleophosmin (117896-08-9)
    Language English
    Publishing date 2021-03-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 752396-8
    ISSN 1873-5835 ; 0145-2126
    ISSN (online) 1873-5835
    ISSN 0145-2126
    DOI 10.1016/j.leukres.2021.106553
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1321: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top