LIVIVO - Search results -

Search results

Result 1 - 10 of total 112

Search options

Article ; Online: Genetics of Exercise and Diet-Induced Fat Loss Efficiency: A Systematic Review.

Bojarczuk, Aleksandra / Egorova, Emiliya S / Dzitkowska-Zabielska, Magdalena / Ahmetov, Ildus I

2024 Volume 23, Issue 1, Page(s) 236–257

Abstract: Physical exercise and dieting are well-known and effective methods for fat loss and improving cardiovascular health. However, different individuals often react differently to the same exercise regimen or dietary plan. While specific individuals may ... ...

Abstract	Physical exercise and dieting are well-known and effective methods for fat loss and improving cardiovascular health. However, different individuals often react differently to the same exercise regimen or dietary plan. While specific individuals may undergo substantial fat loss, others may observe only limited effects. A wide range of inter-individual variability in weight gain and changes in body composition induced by physical exercises and diets led to an investigation into the genetic factors that may contribute to the individual variations in such responses. This systematic review aimed at identifying the genetic markers associated with fat loss resulting from diet or exercise. A search of the current literature was performed using the PubMed database. Forty-seven articles met the inclusion criteria when assessing genetic markers associated with weight loss efficiency in response to different types of exercises and diets. Overall, we identified 30 genetic markers of fat-loss efficiency in response to different kinds of diets and 24 in response to exercise. Most studies (n = 46) used the candidate gene approach. We should aspire to the customized selection of exercise and dietary plans for each individual to prevent and treat obesity.
MeSH term(s)	Humans ; Genetic Markers ; Obesity/genetics ; Obesity/prevention & control ; Exercise ; Weight Loss/genetics ; Diet
Chemical Substances	Genetic Markers
Language	English
Publishing date	2024-03-01
Publishing country	Turkey
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	2075564-8
ISSN	1303-2968 ; 1303-2968
ISSN (online)	1303-2968
ISSN	1303-2968
DOI	10.52082/jssm.2024.236
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Genes and Athletic Performance: The 2023 Update.

Semenova, Ekaterina A / Hall, Elliott C R / Ahmetov, Ildus I

Genes

2023 Volume 14, Issue 6

Abstract: Phenotypes of athletic performance and exercise capacity are complex traits influenced by both genetic and environmental factors. This update on the panel of genetic markers (DNA polymorphisms) associated with athlete status summarises recent advances in ...

Abstract	Phenotypes of athletic performance and exercise capacity are complex traits influenced by both genetic and environmental factors. This update on the panel of genetic markers (DNA polymorphisms) associated with athlete status summarises recent advances in sports genomics research, including findings from candidate gene and genome-wide association (GWAS) studies, meta-analyses, and findings involving larger-scale initiatives such as the UK Biobank. As of the end of May 2023, a total of 251 DNA polymorphisms have been associated with athlete status, of which 128 genetic markers were positively associated with athlete status in at least two studies (41 endurance-related, 45 power-related, and 42 strength-related). The most promising genetic markers include the
MeSH term(s)	Genetic Markers ; Genome-Wide Association Study ; Genotype ; Athletic Performance ; DNA
Chemical Substances	Genetic Markers ; DNA (9007-49-2)
Language	English
Publishing date	2023-06-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes14061235
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Diversity and Differential Expression of MicroRNAs in the Human Skeletal Muscle with Distinct Fiber Type Composition.

Zhelankin, Andrey V / Iulmetova, Liliia N / Ahmetov, Ildus I / Generozov, Eduard V / Sharova, Elena I

Life (Basel, Switzerland)

2023 Volume 13, Issue 3

Abstract: The ratio of fast- and slow-twitch fibers in human skeletal muscle is variable and largely determined by genetic factors. In this study, we investigated the contribution of microRNA (miRNA) in skeletal muscle fiber type composition. The study involved ... ...

Abstract	The ratio of fast- and slow-twitch fibers in human skeletal muscle is variable and largely determined by genetic factors. In this study, we investigated the contribution of microRNA (miRNA) in skeletal muscle fiber type composition. The study involved biopsy samples of the
Language	English
Publishing date	2023-02-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life13030659
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Bibliometric and scientometric analysis on biomarkers and molecular mechanisms for physical frailty and sarcopenia.

Ginevičienė, Valentina / Pranckevičienė, Erinija / Kilaitė, Justina / Mastavičiūtė, Asta / Dadelienė, Rūta / Jamontaitė, Ieva Eglė / Letukienė, Austėja / Ahmetov, Ildus I / Alekna, Vidmantas

Frontiers in medicine

2024 Volume 11, Page(s) 1326764

Abstract: Introduction: The influence of physical frailty and sarcopenia (PFS) on the well-being of older people and continuous pressure on the healthcare systems has prompted a research on the pathophysiology and molecular mechanisms of these conditions. ... ...

Abstract	Introduction: The influence of physical frailty and sarcopenia (PFS) on the well-being of older people and continuous pressure on the healthcare systems has prompted a research on the pathophysiology and molecular mechanisms of these conditions. Nonetheless some biomarkers have been suggested as potential markers for PFS none of them have been shown to highlight the complex nature of PFS, which reveals that there is a need for an understanding of the possible biomarker candidates. The aim of this study was to identify the current research hotspots, status, and trends in the field of biomarkers and molecular mechanisms for PFS. Methods: The bibliometric and scientometric analyses were performed using VOSviewer (version 1.6.18) and open source software platform Cytoscape v.3.9 (for visualizing and constructing a network of keywords). Data of publications (from 1997 to 2023) related to biomarkers and molecular mechanisms of PFS were obtained (in May 2023) from the database of Science Citation Index Expanded of Web of Science, Scopus, and PubMed. The keywords obtained from the Scopus database were used to perform a meaningful keyword analysis. A network of keyword relationships was build using Cytoscape. Results: In this study, we present biomarker keywords for PFS in relation to other keywords potentially designating processes and mechanisms and reveal the biomarker identities and current contexts in which these biomarker identities are discussed. Conclusions: Over recent years, scientific interest in the field of PFS has increased and focused on the inflammatory process and probably will be concentrated on myokines (such as cytokines and small proteins) that are synthetized and released by skeletal muscles in response to physical activity. Moreover, proteomic and genetic markers are deeply involved in PFS.
Language	English
Publishing date	2024-02-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2024.1326764
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Identification and Characterization of Genomic Predictors of Sarcopenia and Sarcopenic Obesity Using UK Biobank Data.

Semenova, Ekaterina A / Pranckevičienė, Erinija / Bondareva, Elvira A / Gabdrakhmanova, Leysan J / Ahmetov, Ildus I

Nutrients

2023 Volume 15, Issue 3

Abstract: The substantial decline in skeletal muscle mass, strength, and gait speed is a sign of severe sarcopenia, which may partly depend on genetic risk factors. So far, hundreds of genome-wide significant single nucleotide polymorphisms (SNPs) associated with ... ...

Abstract	The substantial decline in skeletal muscle mass, strength, and gait speed is a sign of severe sarcopenia, which may partly depend on genetic risk factors. So far, hundreds of genome-wide significant single nucleotide polymorphisms (SNPs) associated with handgrip strength, lean mass and walking pace have been identified in the UK Biobank cohort; however, their pleiotropic effects on all three phenotypes have not been investigated. By combining summary statistics of genome-wide association studies (GWAS) of handgrip strength, lean mass and walking pace, we have identified 78 independent SNPs (from 73 loci) associated with all three traits with consistent effect directions. Of the 78 SNPs, 55 polymorphisms were also associated with body fat percentage and 25 polymorphisms with type 2 diabetes (T2D), indicating that sarcopenia, obesity and T2D share many common risk alleles. Follow-up bioinformatic analysis revealed that sarcopenia risk alleles were associated with tiredness, falls in the last year, neuroticism, alcohol intake frequency, smoking, time spent watching television, higher salt, white bread, and processed meat intake; whereas protective alleles were positively associated with bone mineral density, serum testosterone, IGF1, and 25-hydroxyvitamin D levels, height, intelligence, cognitive performance, educational attainment, income, physical activity, ground coffee drinking and healthier diet (muesli, cereal, wholemeal or wholegrain bread, potassium, magnesium, cheese, oily fish, protein, water, fruit, and vegetable intake). Furthermore, the literature data suggest that single-bout resistance exercise may induce significant changes in the expression of 26 of the 73 implicated genes in m. vastus lateralis, which may partly explain beneficial effects of strength training in the prevention and treatment of sarcopenia. In conclusion, we have identified and characterized 78 SNPs associated with sarcopenia and 55 SNPs with sarcopenic obesity in European-ancestry individuals from the UK Biobank.
MeSH term(s)	Humans ; Sarcopenia/genetics ; Sarcopenia/complications ; Hand Strength ; Diabetes Mellitus, Type 2/complications ; Genome-Wide Association Study ; Biological Specimen Banks ; Obesity/epidemiology ; Obesity/genetics ; Obesity/complications ; Genomics ; United Kingdom/epidemiology ; Muscle, Skeletal
Language	English
Publishing date	2023-02-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15030758
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The

Rahimi, Mohammad Rahman / Semenova, Ekaterina A / Larin, Andrey K / Kulemin, Nikolay A / Generozov, Edward V / Łubkowska, Beata / Ahmetov, Ildus I / Golpasandi, Hadi

Nutrients

2023 Volume 15, Issue 7

Abstract: Caffeine is an adenosine ... ...

Abstract	Caffeine is an adenosine A
MeSH term(s)	Humans ; Caffeine ; Receptor, Adenosine A2A/genetics ; Coffee ; Cross-Over Studies ; Resistance Training ; Acetylcholinesterase ; Heterozygote ; Anti-Inflammatory Agents/pharmacology ; Cytochrome P-450 CYP1A2/genetics ; Genotype
Chemical Substances	Caffeine (3G6A5W338E) ; Receptor, Adenosine A2A ; Coffee ; Acetylcholinesterase (EC 3.1.1.7) ; Anti-Inflammatory Agents ; Cytochrome P-450 CYP1A2 (EC 1.14.14.1)
Language	English
Publishing date	2023-03-28
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15071634
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Genes and Athletic Performance: The 2023 Update

Semenova, Ekaterina A. / Hall, Elliott C. R. / Ahmetov, Ildus I.

Genes (Basel). 2023 June 08, v. 14, no. 6

2023

Abstract	Phenotypes of athletic performance and exercise capacity are complex traits influenced by both genetic and environmental factors. This update on the panel of genetic markers (DNA polymorphisms) associated with athlete status summarises recent advances in sports genomics research, including findings from candidate gene and genome-wide association (GWAS) studies, meta-analyses, and findings involving larger-scale initiatives such as the UK Biobank. As of the end of May 2023, a total of 251 DNA polymorphisms have been associated with athlete status, of which 128 genetic markers were positively associated with athlete status in at least two studies (41 endurance-related, 45 power-related, and 42 strength-related). The most promising genetic markers include the AMPD1 rs17602729 C, CDKN1A rs236448 A, HFE rs1799945 G, MYBPC3 rs1052373 G, NFIA-AS2 rs1572312 C, PPARA rs4253778 G, and PPARGC1A rs8192678 G alleles for endurance; ACTN3 rs1815739 C, AMPD1 rs17602729 C, CDKN1A rs236448 C, CPNE5 rs3213537 G, GALNTL6 rs558129 T, IGF2 rs680 G, IGSF3 rs699785 A, NOS3 rs2070744 T, and TRHR rs7832552 T alleles for power; and ACTN3 rs1815739 C, AR ≥21 CAG repeats, LRPPRC rs10186876 A, MMS22L rs9320823 T, PHACTR1 rs6905419 C, and PPARG rs1801282 G alleles for strength. It should be appreciated, however, that elite performance still cannot be predicted well using only genetic testing.
Keywords	DNA ; athletic performance ; exercise ; genes ; genomics ; meta-analysis ; peroxisome proliferator-activated receptor alpha ; peroxisome proliferator-activated receptor gamma
Language	English
Dates of publication	2023-0608
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2527218-4
ISSN	2073-4425
ISSN	2073-4425
DOI	10.3390/genes14061235
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Agreement between bioimpedance analysis and ultrasound scanning in body composition assessment.

Bondareva, Elvira A / Parfenteva, Olga I / Troshina, Ekaterina A / Ershova, Ekaterina V / Mazurina, Natalya V / Komshilova, Kseniya A / Kulemin, Nikolay A / Ahmetov, Ildus I

American journal of human biology : the official journal of the Human Biology Council

2023 Volume 36, Issue 4, Page(s) e24001

Abstract: Objectives: This study aimed at evaluating the agreement between bioelectrical impedance analysis (BIA) using ABC-02 Medas and A-mode ultrasound (AUS) using BodyMetrix™ BX2000 for fat mass (FM), fat free mass (FFM), and body fat percentage (%BF) in ... ...

Abstract	Objectives: This study aimed at evaluating the agreement between bioelectrical impedance analysis (BIA) using ABC-02 Medas and A-mode ultrasound (AUS) using BodyMetrix™ BX2000 for fat mass (FM), fat free mass (FFM), and body fat percentage (%BF) in females. Methods: The cross-sectional, single-center, observational study was performed in 206 female subjects aged 18-67 years. The examination program included measurements of body height and weight along with waist, hip circumferences, and body composition analysis. The measurements were performed by ultrasound scanner and bioimpedance analyzer. Results: We found that 20.9% of women were obese based on BMI (≥30 kg/m Conclusion: Thus, the proposed equations can be used for conversion of body composition results obtained by AUS into the BIA data.
MeSH term(s)	Female ; Humans ; Absorptiometry, Photon ; Body Composition ; Body Mass Index ; Cross-Sectional Studies ; Electric Impedance ; Obesity/diagnosis ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged
Language	English
Publishing date	2023-10-11
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	1025339-7
ISSN	1520-6300 ; 1042-0533
ISSN (online)	1520-6300
ISSN	1042-0533
DOI	10.1002/ajhb.24001
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2567: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Perspectives in Sports Genomics.

Ginevičienė, Valentina / Utkus, Algirdas / Pranckevičienė, Erinija / Semenova, Ekaterina A / Hall, Elliott C R / Ahmetov, Ildus I

Biomedicines

2022 Volume 10, Issue 2

Abstract: Human athletic performance is a complex phenotype influenced by environmental and genetic factors, with most exercise-related traits being polygenic in nature. The aim of this article is to outline some of the challenge faced by sports genetics as this ... ...

Abstract	Human athletic performance is a complex phenotype influenced by environmental and genetic factors, with most exercise-related traits being polygenic in nature. The aim of this article is to outline some of the challenge faced by sports genetics as this relatively new field moves forward. This review summarizes recent advances in sports science and discusses the impact of the genome, epigenome and other omics (such as proteomics and metabolomics) on athletic performance. The article also highlights the current status of gene doping and examines the possibility of applying genetic knowledge to predict athletes' injury risk and to prevent the rare but alarming occurrence of sudden deaths during sporting events. Future research in large cohorts of athletes has the potential to detect new genetic variants and to confirm the previously identified DNA variants believed to explain the natural predisposition of some individuals to certain athletic abilities and health benefits. It is hoped that this article will be useful to sports scientists who seek a greater understanding of how genetics influences exercise science and how genomic and other multi-omics approaches might support performance analysis, coaching, personalizing nutrition, rehabilitation and sports medicine, as well as the potential to develop new rationale for future scientific investigation.
Language	English
Publishing date	2022-01-27
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines10020298
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Diversity and Differential Expression of MicroRNAs in the Human Skeletal Muscle with Distinct Fiber Type Composition

Andrey V. Zhelankin / Liliia N. Iulmetova / Ildus I. Ahmetov / Eduard V. Generozov / Elena I. Sharova

Life, Vol 13, Iss 659, p

2023 Volume 659

Abstract	The ratio of fast- and slow-twitch fibers in human skeletal muscle is variable and largely determined by genetic factors. In this study, we investigated the contribution of microRNA (miRNA) in skeletal muscle fiber type composition. The study involved biopsy samples of the vastus lateralis muscle from 24 male participants with distinct fiber type ratios. The miRNA study included samples from five endurance athletes and five power athletes with the predominance of slow-twitch (61.6–72.8%) and fast-twitch (69.3–80.7%) fibers, respectively. Total and small RNA were extracted from tissue samples. Total RNA sequencing ( N = 24) revealed 352 differentially expressed genes between the groups with the predominance of fast- and slow-twitch muscle fibers. Small RNA sequencing showed upregulation of miR-206, miR-501-3p and miR-185-5p, and downregulation of miR-499a-5p and miR-208-5p in the group of power athletes with fast-twitch fiber predominance. Two miRtronic miRNAs, miR-208b-3p and miR-499a-5p, had strong correlations in expression with their host genes ( MYH7 and MYH7B , respectively). Correlations between the expression of miRNAs and their experimentally validated messenger RNA (mRNA) targets were calculated, and 11 miRNA–mRNA interactions with strong negative correlations were identified. Two of them belonged to miR-208b-3p and miR-499a-5p, indicating their regulatory links with the expression of CDKN1A and FOXO4 , respectively.
Keywords	microRNA ; miRNome ; transcriptome ; muscle fiber type ; power athlete ; endurance athlete ; Science ; Q
Subject code	796 ; 500
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED