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  1. Article ; Online: The minimally invasive sacrospinous fixation under visual guidance: An anatomical study.

    Chene, Gautier / Cerruto, Emanuele / Moret, Stephanie / Nohuz, Erdogan

    European journal of obstetrics, gynecology, and reproductive biology

    2024  Volume 297, Page(s) 36–39

    Abstract: Objective: Sacrospinous fixation is the gold standard procedure for management of apical pelvic organ prolapse by the vaginal route. However, there may be a relevant risk of neurovascular injury due to the proximity of neurovascular structures. We ... ...

    Abstract Objective: Sacrospinous fixation is the gold standard procedure for management of apical pelvic organ prolapse by the vaginal route. However, there may be a relevant risk of neurovascular injury due to the proximity of neurovascular structures. We propose an anatomical study concerning the sacrospinous ligament with a new innovative minimally invasive technology using both a suture capturing device and a chip-on-the-tip endoscope to perform sacropinous fixation.
    Study design: Bilateral sacrospinous fixation was performed in three female cadavers, in the course of the anatomical study conducted with a specific device (the Suture Capturing I Stitch™ Device) under real time visual guidance with a chip-on -the-tip endoscope, the NanoScope™ system.
    Results: Identification of ischial spine and sacrospinous ligament as well as feasibility of sacrospinous fixation under NanoScope™ control were always possible on both sides.
    Conclusions: This new innovative minimally invasive technology using both a suture capturing device and a chip-on-the-tip endoscope is relevant and could be an advantage in terms of safety and better placement of the suture on the sacrospinous ligament.
    Language English
    Publishing date 2024-03-31
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2024.03.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Mid-Term Results of a New Transobturator Cystocele Repair by Vaginal Patch Plastron without Mesh.

    Chene, Gautier / Cerruto, Emanuele / Moret, Stephanie / Nohuz, Erdogan

    Journal of clinical medicine

    2023  Volume 12, Issue 14

    Abstract: Cystoceles are the most common prolapses. Limitation of the use of synthetic mesh has led to the comeback of native tissue repair procedures. We have developed a new transobturator technique with native tissue based on a mix of a vaginal plastron ... ...

    Abstract Cystoceles are the most common prolapses. Limitation of the use of synthetic mesh has led to the comeback of native tissue repair procedures. We have developed a new transobturator technique with native tissue based on a mix of a vaginal plastron technique and the transobturator procedure. We present the functional and anatomical mid-term results. In this retrospective study, the vaginal plastron technique and the transobturator procedure were performed in 32 patients. Functional assessment with several validated quality-of-life questionnaires (SF-12, PFIQ-7, PFDI-20, PISQ12) and anatomical evaluation with pelvic examination were performed at 1, 6, and 12 months after surgery. The anatomical success rate was 94.4% at 12 months. There was one Clavien-Dindo grade 2 postoperative complication (one urinary tract infection). All of the quality-of-life scores were statistically significantly improved at one year follow-up. The transobturator technique combined with the vaginal plastron seems to be a promising, effective, innovative, and relevant technique for the repair of high-stage cystoceles.
    Language English
    Publishing date 2023-07-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12144582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Long-Term Results after Bilateral Sacrospinous Colposuspension: A Prospective Study.

    Chene, Gautier / Cerruto, Emanuele / Moret, Stephanie / Nohuz, Erdogan

    Journal of clinical medicine

    2023  Volume 12, Issue 14

    Abstract: The loss of apical support is usually present in patients with pelvic organ prolapse. An effective correction for the vaginal apex may be an essential part of a durable repair for these women. Apical suspension of the sacrospinous ligament is likely one ... ...

    Abstract The loss of apical support is usually present in patients with pelvic organ prolapse. An effective correction for the vaginal apex may be an essential part of a durable repair for these women. Apical suspension of the sacrospinous ligament is likely one of the best treatments by the vaginal route. We proposed the evaluation of the functional and anatomical long-term results of an ultralight and macroporous sling. In this prospective study, bilateral sacrospinous colposuspension was performed in 32 patients with a specific mesh. Functional assessment with several validated quality of life questionnaires and pelvic examination was performed at 1, 6, 12, and 24 months after surgery. Pelvic examination using the POP-Q classification showed a very good efficacy of the BSC mesh with only three prolapse recurrences at 24 months after surgery. All the following QoL scores were significantly improved by two years: PFIQ-7 (
    Language English
    Publishing date 2023-07-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12144691
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Essure

    Chene, Gautier / Cerruto, Emanuele / Nohuz, Erdogan

    Journal of the Turkish German Gynecological Association

    2021  Volume 22, Issue 1, Page(s) 83–84

    Abstract: Many women request ... ...

    Abstract Many women request Essure
    Language English
    Publishing date 2021-01-28
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2425806-4
    ISSN 1309-0380 ; 1303-9695 ; 1309-0399
    ISSN (online) 1309-0380 ; 1303-9695
    ISSN 1309-0399
    DOI 10.4274/jtgga.galenos.2020.2020.0159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Could the anatomic location of Essure® device explain the impairment of quality of life?

    Chene, Gautier / Cerruto, Emanuele / Moret, Stéphanie / Nohuz, Erdogan

    Minerva obstetrics and gynecology

    2022  Volume 74, Issue 2, Page(s) 123–129

    Abstract: Background: Since health-related quality of life (HRQL) could improve after removal of Essure: Methods: Correct and incorrect placed Essure: Results: Sixty-five patients were included in the study divided in two groups (group A with correct ... ...

    Abstract Background: Since health-related quality of life (HRQL) could improve after removal of Essure
    Methods: Correct and incorrect placed Essure
    Results: Sixty-five patients were included in the study divided in two groups (group A with correct placement: 45 patients and group B with incorrect placement: 20 patients). HRQL and Pain Index were improved in both groups at 6 months post-surgery. There was not any statistically significant difference between group A and B. The PBAC score increased at 6 months postoperatively in group A and B without any statistically significant difference between them.
    Conclusions: Postoperative improvement of quality of life and pain index was similar whatever the position of the implant. This suggests that symptomatology and quality of life are not related to the anatomic location of the Essure
    MeSH term(s) Device Removal ; Female ; Humans ; Laparoscopy ; Pain ; Quality of Life ; Sterilization, Tubal
    Language English
    Publishing date 2022-04-12
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062815-5
    ISSN 2724-6450
    ISSN (online) 2724-6450
    DOI 10.23736/S2724-606X.21.04728-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Plasma and peritoneal fluid cytokine profiles in patient with Essure® implant: Towards a molecular signature?

    Garnier, Lorna / Parant, François / Bulteau, Claire / Pescarmona, Remi / Cerruto, Emanuele / Moret, Stephanie / Miguet-Bensouda, Chloe / Nohuz, Erdogan / Chene, Gautier

    European journal of obstetrics, gynecology, and reproductive biology

    2024  Volume 296, Page(s) 349–353

    Abstract: Objective(s): Many patients with Essure® implant may experience adverse events related to the device. Although local inflammation does not appear to be the pathophysiological mechanism underlying the symptoms, systemic inflammation could play a role. In ...

    Abstract Objective(s): Many patients with Essure® implant may experience adverse events related to the device. Although local inflammation does not appear to be the pathophysiological mechanism underlying the symptoms, systemic inflammation could play a role. In the present study, as cytokines are involved in the inflammatory process, we proposed to investigate the profile of circulating and peritoneal cytokines.
    Study design: In this retrospective study, we evaluated the levels of cytokines in peritoneal fluid (PF) as well as in plasma sample from three different groups: Essure® group, endometriosis group (known to be associated with immune dysregulation), and control group.
    Results: There were 60 symptomatic patients with Essure® device, 30 patients with endometriosis and a control group of 30 patients. The PF levels of Interleukin-10 (IL-10), Interleukin-6 (IL-6), and Monocyte chemoattractant protein-1 (MCP-1) were statistically higher in endometriosis group than in Essure® group and control group. The plasma level of MCP-1 was higher in Essure® group than in endometriosis group and control group. The plasma level of TNF-α was higher in Essure® group than in control group.
    Conclusions: The chemokine MCP-1 as well as the pro-inflammatory TNF-α, are known to be increased in patients with fibromyalgia and chronic fatigue syndrome. Since patients with Essure® may exhibit symptoms similar to fibromyalgia, MCP-1 and TNF-α may be relevant markers in symptomatic patients with Essure®. Because of the lack of longitudinal data (no evaluation of postoperative cytokine profile and no assessment of the level of clinical improvement), other studies are needed to confirm these preliminary results.
    MeSH term(s) Female ; Humans ; Tumor Necrosis Factor-alpha ; Endometriosis ; Retrospective Studies ; Ascitic Fluid ; Fibromyalgia ; Cytokines ; Interleukin-6 ; Inflammation
    Chemical Substances Tumor Necrosis Factor-alpha ; Cytokines ; Interleukin-6
    Language English
    Publishing date 2024-03-26
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2024.03.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Clinical improvement after Essure® devices removal: a systematic review.

    Miguet-Bensouda, Chloe / Parant, Francois / Grenet, Guillaume / Cerruto, Emanuele / Nohuz, Erdogan / Chene, Gautier

    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception

    2023  Volume 28, Issue 4, Page(s) 238–248

    Abstract: Purpose: Essure® implant is a permanently implanted minimally invasive birth control device for women (female sterilisation) widely used between 2002 and 2018. Many adverse events were reported by patients. Increasingly removal procedures have been ... ...

    Abstract Purpose: Essure® implant is a permanently implanted minimally invasive birth control device for women (female sterilisation) widely used between 2002 and 2018. Many adverse events were reported by patients. Increasingly removal procedures have been performed in symptomatic patients. However, there is a lack of in-depth studies on clinical improvement after Essure® removal. We aimed to review all clinical studies about symptoms and quality of life (QoL) after removal procedures.
    Materials and methods: A review of literature in electronic search in Medline and Embase databases from January 2002 to January 2022 using the following keywords: Essure; Essure removal; quality of life; symptomatology improvement.
    Results: Out of 764 articles in the initial database, 18 clinical studies were eligible for inclusion in our literature review. Overall clinical improvement rates after removal ranged from 21% to 98%. All symptoms were less frequent after Essure® removal, although with large discrepancies between studies. Lack of improvement was reported between 1% to 15% of patients. Rate of patients with improvement of QoL after removal ranged from 58 to 98%. The pain was reported as significantly reduced after the surgery.
    Conclusions: In the available literature, Essure® removal in symptomatic patients may improve symptoms and quality of life. This should be discussed in the benefits and risks ratio before deciding on the best option of management.
    MeSH term(s) Pregnancy ; Female ; Humans ; Hysteroscopy/methods ; Quality of Life ; Sterilization, Tubal/adverse effects ; Sterilization, Reproductive ; Salpingectomy/methods ; Device Removal/methods
    Language English
    Publishing date 2023-07-19
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1397560-2
    ISSN 1473-0782 ; 1362-5187
    ISSN (online) 1473-0782
    ISSN 1362-5187
    DOI 10.1080/13625187.2023.2236741
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  8. Article ; Online: Anterior sacrospinous ligament fixation by the vaginal route in ten steps.

    de Boisredon, Maïti / Nohuz, Erdogan / Chene, Gautier / Philip, Charles-André / Lamblin, Gery

    Journal of gynecology obstetrics and human reproduction

    2023  Volume 52, Issue 10, Page(s) 102677

    Abstract: Pelvic organ prolapse (POP) is a common condition affecting women, characterized by the descent of pelvic organs such as the vagina and uterus. While POP may not always cause symptoms, it can significantly impact a woman's quality of life. Diagnosis is ... ...

    Abstract Pelvic organ prolapse (POP) is a common condition affecting women, characterized by the descent of pelvic organs such as the vagina and uterus. While POP may not always cause symptoms, it can significantly impact a woman's quality of life. Diagnosis is typically made through clinical examination, and treatment options range from pelvic-floor physical therapy to surgery. Anterior sacrospinous ligament fixation (ASSLF) has emerged as a viable technique for treating apical prolapse vaginally. This procedure involves attaching the cervix or vaginal vault to the sacrospinous ligament, providing satisfactory results in the short term. Compared to the posterior approach, ASSLF shows similar efficacy, shorter operative time, and potentially fewer complications. Vaginal surgery offers advantages such as lower morbidity and cost, ability to address other pelvic conditions simultaneously, and suitability for managing recurrences. The presented case involves a 72-year-old woman with stage 3 cystocele, stage 3 hysterocele, stage 1 rectocele, and severe voiding dysfunction. After unsuccessful attempts with a pessary, surgical intervention becomes necessary. An instructive video article has been created to standardize the essential steps of ASSLF and facilitate resident education. The video demonstrates ten surgical steps, including installation/exposure, anterior vaginal wall infiltration, median anterior colpotomy, vesico-vaginal dissection, paravesical dissection, sacrospinous ligament suture, cystocele correction, colpotomy and vaginal wall repair, uterine anterior isthmus suture and sacrospinous ligament fixation, and colporrhaphy final closure. In conclusion, POP is a prevalent condition that can be effectively managed through techniques like ASSLF. Vaginal surgery offers several advantages, and proper training and standardization of surgical steps contribute to successful outcomes and resident education.
    MeSH term(s) Female ; Humans ; Aged ; Cystocele ; Quality of Life ; Pelvic Organ Prolapse/surgery ; Vagina/surgery ; Ligaments/surgery
    Language English
    Publishing date 2023-10-10
    Publishing country France
    Document type Video-Audio Media ; Case Reports ; Journal Article
    ISSN 2468-7847
    ISSN (online) 2468-7847
    DOI 10.1016/j.jogoh.2023.102677
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  9. Article: Disseminated Nocardiosis in a Breast Cancer Patient Caused by Nocardia otitidiscaviarum: A Case Report of Tertiary Centre in Saudi Arabia.

    Kullab, Sharif / Basamad, Salem W / Alnwaisir, Mosaad / Alhowari, Mai / Nohuz, Erdogan

    Cureus

    2022  Volume 14, Issue 2, Page(s) e22686

    Abstract: Nocardiosis is a rare opportunistic disease that primarily affects patients with deficient immune systems. ...

    Abstract Nocardiosis is a rare opportunistic disease that primarily affects patients with deficient immune systems.
    Language English
    Publishing date 2022-02-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.22686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: No, it is not a third breast that grows!

    Nohuz, Erdogan / Bui, Marie-Claire

    The Pan African medical journal

    2018  Volume 30, Page(s) 213

    MeSH term(s) Breast/pathology ; Dermatofibrosarcoma/diagnosis ; Dermatofibrosarcoma/pathology ; Female ; Humans ; Middle Aged ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology
    Language English
    Publishing date 2018-07-16
    Publishing country Uganda
    Document type Case Reports ; Journal Article
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2018.30.213.16402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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