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  1. Book: Cognitive remediation to improve functional outcomes

    Medalia, Alice / Bowie, Christopher R.

    2016  

    Author's details edited by Alice Medalia and Christopher R. Bowie
    Keywords Cognition Disorders / rehabilitation ; Cognitive Therapy / methods
    Language English
    Size xiv, 212 Seiten, Illustrationen, Diagramme, 24 cm
    Edition First edition
    Publisher Oxford University Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019077225
    ISBN 978-0-19-939522-4 ; 0-19-939522-5
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Implementation of Cognitive Health Services in Large Systems of Care: Highlights From Coordinated Specialty Care for First Episode Psychosis.

    Saperstein, Alice M / Bello, Iruma / Nossel, Ilana / Dixon, Lisa B / Medalia, Alice

    Schizophrenia bulletin

    2024  

    Abstract: Background and hypothesis: With increasing recognition of the importance of cognitive health for recovery in people with psychosis, questions arise as to how to implement cognitive health services in large systems of care. This paper describes the ... ...

    Abstract Background and hypothesis: With increasing recognition of the importance of cognitive health for recovery in people with psychosis, questions arise as to how to implement cognitive health services in large systems of care. This paper describes the implementation of cognitive health services in OnTrackNY (OTNY), a network of clinics delivering a Coordinated Specialty Care treatment model for early psychosis, with the goal of documenting the processes, challenges, and useful adaptations.
    Study design: In 2018, OTNY piloted a Cognitive Health Toolkit for implementation across 18 affiliated clinics. The toolkit intended to identify the cognitive health needs of individuals early in the course of psychosis and to integrate cognitive health into the vocabulary of wellness and recovery. Implementation involved creating mechanisms for staff training and support to, in turn, help participants improve how they use cognitive skills in daily life.
    Study results: The toolkit was disseminated to all 28 OTNY programs throughout New York state by 2023. When simple assessment and decision-making tools were embedded in routine care practices, the majority of participants identified that improving memory, attention, and critical thinking skills would be helpful. Consistently, about 70% of those asked wanted to learn more about how to better their cognitive health.
    Conclusions: Cognitive health services can be implemented in large systems of care that provide a multi-level system of implementation supports. Organizational facilitators of implementation include a training program to educate about cognitive health and the delivery of cognitive health interventions, and embedded quality assurance monitoring and improvement activities.
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 439173-1
    ISSN 1745-1701 ; 0586-7614
    ISSN (online) 1745-1701
    ISSN 0586-7614
    DOI 10.1093/schbul/sbae030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correlates of hearing loss among adults with schizophrenia.

    Saperstein, Alice M / Meyler, Shanique / Golub, Justin S / Medalia, Alice

    Schizophrenia research

    2023  Volume 257, Page(s) 1–4

    Abstract: Background: Hearing loss (HL) is associated with adverse cognitive, mental, and physical health outcomes. There is evidence that across age groups HL is more prevalent in people with schizophrenia than the general population. Given that people with ... ...

    Abstract Background: Hearing loss (HL) is associated with adverse cognitive, mental, and physical health outcomes. There is evidence that across age groups HL is more prevalent in people with schizophrenia than the general population. Given that people with schizophrenia may already be vulnerable to cognitive and psychosocial disability, we sought to examine how hearing ability relates to concurrent levels of cognitive, mental and daily functioning.
    Methods: Community-dwelling adults with schizophrenia (N = 84) ages 22-50 completed pure tone audiometry assessments. Hearing threshold (in decibels) was defined as the lowest detectable pure tone at 1000 Hz. Pearson correlation was used to test the hypothesis that higher hearing thresholds (worse hearing) would be significantly associated with poorer performance on the Brief Assessment of Cognition in Schizophrenia (BACS). Additional analyses explored the relationships between audiometric threshold and functional capacity measured with the Virtual Reality Functional Capacity Assessment Tool (VRFCAT) and symptoms severity rated on the Positive and Negative Syndrome Scale (PANSS).
    Results: Hearing threshold was inversely and significantly correlated with the BACS composite score (r = -0.27, p = 0.017). This relationship was reduced but remained significant after controlling for age (r = -0.23, p = 0.04). Hearing threshold was not associated with VRFCAT or psychiatric symptom measures.
    Conclusions: While schizophrenia and HL are independently associated with cognitive impairment, the magnitude of impairment in this sample was greater among those with poorer hearing. Findings warrant further mechanistic study of the relationship between hearing impairment and cognition and have implications for addressing modifiable health risk factors for higher morbidity and mortality in this vulnerable population.
    MeSH term(s) Humans ; Adult ; Schizophrenia ; Hearing Loss/epidemiology ; Hearing ; Cognitive Dysfunction/psychology ; Audiometry, Pure-Tone
    Language English
    Publishing date 2023-05-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2023.05.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Hearing Loss in Older People With Schizophrenia: Audiologic Characteristics and Association With Psychosocial Functioning.

    Saperstein, Alice M / Subhan, Bibi A / Golub, Justin S / Medalia, Alice

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2023  Volume 32, Issue 4, Page(s) 489–496

    Abstract: Objective: The severity and impact of hearing deficits among adults with schizophrenia spectrum disorders may become increasingly relevant with advancing age. This study evaluated hearing ability and associated psychosocial functioning among older ... ...

    Abstract Objective: The severity and impact of hearing deficits among adults with schizophrenia spectrum disorders may become increasingly relevant with advancing age. This study evaluated hearing ability and associated psychosocial functioning among older adults aged 50-70.
    Design: Cross-sectional analysis.
    Setting: Four outpatient psychiatry clinics in New York City.
    Participants: Individuals aged 50-70 years with diagnoses of schizophrenia or schizoaffective disorder.
    Measurements: Unaided pure tone air conduction audiometry conducted using a portable audiometry system determined the pure tone average (PTA) hearing threshold across four frequencies: 500, 1k, 2k, and 4k Hz. Better ear PTA defined the hearing threshold. Audiometry data retrieved from the U.S. National Health and Nutrition Examination Survey aided interpretation of sample hearing loss rates. Standard measures evaluated psychiatric symptoms, perceived impact of hearing impairment, loneliness, and quality of life.
    Results: Among audiometry completers (N = 40), 35% (n = 14) demonstrated subclinical hearing loss (16-25 dB) and 35% (n = 14) had mild or worse hearing loss (≥26 dB). Rates were higher than expected based on age-based population data. Those who perceived hearing handicap rated it moderate (12.2%) or severe (7.3%); those who perceived tinnitus rated the impact as mild to moderate (12.2%) or catastrophic (2.4%). Neither psychiatric symptoms nor interviewer-rated quality of life was associated with hearing ability. Greater loneliness was significantly correlated with worse audiologic performance (r = 0.475, p <0.01) and greater perceived hearing handicap (r = 0.480, p <0.01).
    Conclusion: Identifying the need for hearing loss treatment among aging adults with schizophrenia spectrum disorders is important given the potential implications for social functioning, cognitive, and mental health.
    MeSH term(s) Humans ; Aged ; Quality of Life ; Nutrition Surveys ; Psychosocial Functioning ; Schizophrenia/complications ; Schizophrenia/epidemiology ; Cross-Sectional Studies ; Hearing Loss/complications ; Hearing Loss/epidemiology ; Hearing Loss/diagnosis ; Audiometry, Pure-Tone
    Language English
    Publishing date 2023-11-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2023.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Hearing Loss Among People With Schizophrenia: Implications for Clinical Practice.

    Saperstein, Alice M / Meyler, Shanique / Medalia, Alice

    Psychiatric services (Washington, D.C.)

    2022  Volume 74, Issue 5, Page(s) 543–546

    Abstract: Objective: The authors characterized hearing loss among individuals diagnosed as having schizophrenia to inform provision of routine behavioral health services to this population.: Methods: Audiometry data collected between October 2019 and December ... ...

    Abstract Objective: The authors characterized hearing loss among individuals diagnosed as having schizophrenia to inform provision of routine behavioral health services to this population.
    Methods: Audiometry data collected between October 2019 and December 2021 from 84 community-dwelling adults with schizophrenia and 81 age-matched participants without the condition were analyzed. Rates of hearing loss were identified within groups and across age decades (20-50 years). Hearing threshold and rates of hearing loss were compared between groups.
    Results: Participants with schizophrenia had significantly higher mean hearing thresholds (p=0.006), indicating worse hearing. This difference remained significant after controlling for age (p=0.01). A significantly larger proportion of participants with schizophrenia had mild hearing loss (24%) compared with age-matched participants (6%) (p
    Conclusions: Screening for and detection of hearing loss among adults with schizophrenia may be an unmet need. Hearing loss is a treatable source of cognitive and psychosocial disability, warranting scalable assessment and intervention practices.
    MeSH term(s) Adult ; Humans ; Young Adult ; Middle Aged ; Schizophrenia/epidemiology ; Hearing Loss/epidemiology ; Hearing Loss/diagnosis ; Deafness ; Audiometry
    Language English
    Publishing date 2022-09-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1220173-x
    ISSN 1557-9700 ; 1075-2730
    ISSN (online) 1557-9700
    ISSN 1075-2730
    DOI 10.1176/appi.ps.20220226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: National Cohort Data Suggests an Association Between Serious Mental Illness and Audiometric Hearing Loss.

    Alter, Isaac L / Tucker, Lauren H / Dragon, Jacqueline M / Grewal, Maeher R / Saperstein, Alice / Stroup, T Scott / Medalia, Alice A / Golub, Justin S

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2024  

    Abstract: Objective: To explore whether there is an association between serious mental illness (SMI) and hearing loss (HL) among US Hispanic adults.: Study design and setting: Cross-sectional epidemiological study (Hispanic Community Health Study), including ... ...

    Abstract Objective: To explore whether there is an association between serious mental illness (SMI) and hearing loss (HL) among US Hispanic adults.
    Study design and setting: Cross-sectional epidemiological study (Hispanic Community Health Study), including multicentered US volunteers.
    Methods: Multivariable linear regressions were conducted to study the association between SMI and HL. Adjustments were made for potential confounders including age, sex, education, vascular disease (hypertension or diabetes mellitus), and cognition. SMI was defined by (1) antipsychotic medication classification and (2) the use of at least 1 antipsychotic medication specifically used to treat SMI in clinical psychiatric practice. HL was measured by pure tone audiometry.
    Results: A total of 7581 subjects had complete data. The mean age was 55.2 years (SD = 7.5 years) and the mean pure tone average in the better ear was 16.8 dB (SD = 10.7 dB). A total of 194 (2.6%) subjects were taking a HCHS-defined antipsychotic and 98 (1.3%) were taking at least 1 antipsychotic specifically used to treat SMI. On multivariable regression, use of HCHS's classified antipsychotics was associated with 3.75 dB worse hearing (95% confidence interval [CI] = 2.36-5.13, P < .001) and use of antipsychotics specific for SMI was associated with 4.49 dB worse hearing (95% CI = 2.56-6.43, P < .001) compared to those not using antipsychotics.
    Conclusion: SMI, as defined by either the use of HCHS-defined antipsychotics or the use of antipsychotic medication specific for SMI, is associated with worse hearing, controlling for potential confounders. Whether SMI contributes to HL, antipsychotic medication (through ototoxicity) contributes to HL, or whether HL contributes to SMI is unknown and warrants further investigation.
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1002/ohn.763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Feasibility and clinical utility of using the tone matching test for assessment of early auditory processing in schizophrenia.

    Medalia, Alice / Saperstein, Alice / Javitt, Daniel C / Qian, Min / Meyler, Shanique / Styke, Sarah

    Psychiatry research

    2023  Volume 323, Page(s) 115152

    Abstract: Early auditory processing (EAP) deficits are prevalent in schizophrenia and linked to disturbances in higher order cognition and daily functioning. Treatments that target EAP have the potential to drive downstream cognitive and functional improvements, ... ...

    Abstract Early auditory processing (EAP) deficits are prevalent in schizophrenia and linked to disturbances in higher order cognition and daily functioning. Treatments that target EAP have the potential to drive downstream cognitive and functional improvements, but clinically feasible means to detect EAP impairment are lacking. This report describes the clinical feasibility and utility of using the Tone Matching (TM) Test to assess EAP in adults with schizophrenia. Clinicians were trained to administer the TM Test as part of a baseline cognitive battery to inform choice of cognitive remediation (CR) exercises. Only if the TM Test indicated EAP impairment, were the recommended CR exercises to include EAP training. Results indicated clinicians included the TM Test in all baseline assessments and identified 51.72% as EAP impaired. There were significant positive relationships between TM Test performance and cognitive summary scores, confirming instrumental validity. All clinicians found the TM Test useful for CR treatment planning. CR participants with impaired EAP spent significantly more training time on EAP exercises compared to CR participants with intact EAP (20.11% vs 3.32%). This study found that it is feasible to use the TM Test in community clinics and the test was perceived as clinically useful for personalizing treatment.
    MeSH term(s) Adult ; Humans ; Schizophrenia/complications ; Schizophrenia/diagnosis ; Schizophrenia/therapy ; Feasibility Studies ; Auditory Perception ; Cognition Disorders/psychology ; Cognition
    Language English
    Publishing date 2023-03-07
    Publishing country Ireland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0925-4927 ; 0165-1781
    DOI 10.1016/j.psychres.2023.115152
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Disparities in technology literacy and access negatively impact cognitive remediation scalability.

    Arlia, Christina / Saperstein, Alice M / Meyler, Shanique / Styke, Sarah / Medalia, Alice

    Schizophrenia research

    2022  Volume 243, Page(s) 456–457

    MeSH term(s) Cognitive Remediation ; Health Status Disparities ; Healthcare Disparities ; Humans ; Literacy ; Technology
    Language English
    Publishing date 2022-04-30
    Publishing country Netherlands
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2022.04.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The Design, Implementation, and Acceptability of a Telehealth Comprehensive Recovery Service for People With Complex Psychosis Living in NYC During the COVID-19 Crisis.

    Lynch, David A / Medalia, Alice / Saperstein, Alice

    Frontiers in psychiatry

    2020  Volume 11, Page(s) 581149

    Abstract: Introduction: The COVID-19 crisis and subsequent stay-at-home orders have produced unprecedented challenges to the dissemination of recovery oriented behavioral health services (RS) that support the treatment of those with complex psychosis (CP).This ... ...

    Abstract Introduction: The COVID-19 crisis and subsequent stay-at-home orders have produced unprecedented challenges to the dissemination of recovery oriented behavioral health services (RS) that support the treatment of those with complex psychosis (CP).This population has typically been managed with in-person pharmacotherapy and/or RS, with the goals of relieving symptoms, improving life satisfaction and increasing community engagement. COVID-19 related social distancing measures have required rapid shifts in care management, while easing of telehealth regulations has allowed for flexibility to approach RS differently. It is essential to learn from the RS telemedicine implementation experience, so that RSs can maintain care for this vulnerable and needy population.
    Method: This paper describes the successful telehealth conversion of a NYC-based, university affiliated RS that serves adults with severe mental illnesses (SMI;
    Results: The RS continued providing services including intake, care coordination, group psychotherapies, skills training groups, individual skills coaching, and vocational/educational supports. The telehealth conversion rates of the CP subsample indicated that 90% of CP patients accepted telehealth sessions and maintained their specific treatment plans in the virtual format. Mean comparisons between session attendance and cancellations/no-shows during the six-week period before and after telehealth conversion showed no significant differences in service utilization.
    Discussion: RSs play an essential role in the treatment of CP and telehealth may prove to be a viable format of care delivery even after the COVID-19 crisis subsides. The multiple factors in the inner and outer treatment setting that contributed to successful conversion to telehealth will be considered along with the challenges that clinicians and patients encountered.
    Keywords covid19
    Language English
    Publishing date 2020-09-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2020.581149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Cognitive remediation for psychotic and affective disorders.

    Medalia, Alice

    Canadian journal of psychiatry. Revue canadienne de psychiatrie

    2013  Volume 58, Issue 6, Page(s) 309–310

    MeSH term(s) Cognition Disorders/rehabilitation ; Cognitive Therapy/trends ; Emotional Intelligence ; Humans ; Neuropsychological Tests ; Schizophrenia/rehabilitation ; Schizophrenic Psychology
    Language English
    Publishing date 2013-06
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 304227-3
    ISSN 1497-0015 ; 0706-7437 ; 0008-4824
    ISSN (online) 1497-0015
    ISSN 0706-7437 ; 0008-4824
    DOI 10.1177/070674371305800601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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