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  1. Article ; Online: Single-Dose Ad26.COV2.S Vaccine-Room for Improvement.

    Tehrani, Zahra Rikhtegaran / Sajadi, Mohammad M

    JAMA network open

    2021  Volume 4, Issue 11, Page(s) e2133012

    MeSH term(s) Ad26COVS1 ; Antibodies, Neutralizing ; COVID-19 ; COVID-19 Vaccines ; Humans ; SARS-CoV-2
    Chemical Substances Ad26COVS1 ; Antibodies, Neutralizing ; COVID-19 Vaccines
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.33012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Death of a medical colossus: The course, cause and fatal outcome of Avicenna's colic.

    DuPont, Herbert L / Sajadi, Mohammad M / Mackowiak, Philip A

    The American journal of the medical sciences

    2023  Volume 365, Issue 5, Page(s) 409–412

    Abstract: Abu-'Ali al-Husayn ibn Abdallah ibn-Sina (known in the West as Avicenna) is revered in much of Asia as one of history's greatest physicians. And yet, few westerners know of him, his iconic Canon of Medicine or the role he played in preserving ancient ... ...

    Abstract Abu-'Ali al-Husayn ibn Abdallah ibn-Sina (known in the West as Avicenna) is revered in much of Asia as one of history's greatest physicians. And yet, few westerners know of him, his iconic Canon of Medicine or the role he played in preserving ancient Greek medical knowledge following the sack of Rome. We briefly review Avicenna's impressive legacy and provide what to our knowledge is the first critical examination of the illness responsible for his death at age 58 years.
    MeSH term(s) Humans ; Male ; History, Medieval ; Middle Aged ; Colic ; Physicians ; Medicine ; Asia ; Medicine, Arabic
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 82078-7
    ISSN 1538-2990 ; 0002-9629
    ISSN (online) 1538-2990
    ISSN 0002-9629
    DOI 10.1016/j.amjms.2022.12.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Relationship between Metabolic Syndrome Components and Severity of Asthma in Outpatients Referring to Alzahra Hospital Clinic.

    Emami-Ardestani, Mohammad / Sajadi, Ghazaleh

    Tanaffos

    2022  Volume 20, Issue 4, Page(s) 327–331

    Abstract: Background: Metabolic syndrome is the most common problem worldwide associated with numerous complications. Some studies indicated that metabolic syndrome is associated with asthma; therefore, this study aimed to investigate the possible relationship ... ...

    Abstract Background: Metabolic syndrome is the most common problem worldwide associated with numerous complications. Some studies indicated that metabolic syndrome is associated with asthma; therefore, this study aimed to investigate the possible relationship between metabolic syndrome components and severity of asthma in outpatients referring to Alzahra Hospital in Isfahan, Iran.
    Materials and methods: This descriptive cross-sectional study was performed on 200 patients with asthma referring to Alzahra Lung Clinic in Isfahan, Iran, within 2018-2020. The severity of asthma was evaluated by the Guidelines for the Diagnosis and Management of Asthma by the National Institutes of Health. The association between different categories of asthma severity and metabolic syndrome was investigated.
    Results: The patients were divided into four categories according to the severity of asthma, including intermittent (n=63), mild (n=63), moderate (n=56), and severe (n=18). Moreover, 38.5% (n=77) of patients had metabolic syndrome, and there was no significant relationship between different categories of asthma severity and metabolic syndrome (P=0.73).
    Conclusion: The prevalence of metabolic syndrome is high among patients with asthma; however, there was no significant relationship between metabolic syndrome and different categories of asthma severity.
    Language English
    Publishing date 2022-09-28
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2233372-1
    ISSN 1735-0344
    ISSN 1735-0344
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  4. Article: Movement examination of the lumbar spine using a developed wearable motion sensor.

    Abbasi-Kesbi, Reza / Fathi, Mohammad / Sajadi, Seyed Zaniyar

    Healthcare technology letters

    2023  Volume 10, Issue 6, Page(s) 122–132

    Abstract: A system for monitoring spinal movements based on wearable motion sensors is proposed here. For this purpose, a hardware system is first developed that measures data of linear acceleration, angular velocity, and the magnetic field of the spine. Then, the ...

    Abstract A system for monitoring spinal movements based on wearable motion sensors is proposed here. For this purpose, a hardware system is first developed that measures data of linear acceleration, angular velocity, and the magnetic field of the spine. Then, the obtained data from these sensors are combined in a proposed complementary filter, and their angular variations are estimated. The obtained results of angular variation of this system in comparison with an accurate reference illustrate that the root mean squared error is less than 1.61 degrees for three angles of
    Language English
    Publishing date 2023-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2782924-8
    ISSN 2053-3713
    ISSN 2053-3713
    DOI 10.1049/htl2.12063
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  5. Article: Using of artificial neural networks and different evolutionary algorithms to predict the viscosity and thermal conductivity of silica-alumina-MWCN/water nanofluid.

    Baghoolizadeh, Mohammadreza / Jasim, Dheyaa J / Sajadi, S Mohammad / Renani, Reza Rostamzadeh- / Renani, Mohammad Rostamzadeh- / Hekmatifar, Maboud

    Heliyon

    2024  Volume 10, Issue 4, Page(s) e26279

    Abstract: This study predicts the parameters such as viscosity and thermal conductivity in silica-alumina-MWCN/water nanofluid using the artificial intelligence method and using design variables such as solid volume fraction and temperature. In this study, 6 ... ...

    Abstract This study predicts the parameters such as viscosity and thermal conductivity in silica-alumina-MWCN/water nanofluid using the artificial intelligence method and using design variables such as solid volume fraction and temperature. In this study, 6 optimization algorithms were used to predict and numerically model the μ
    Language English
    Publishing date 2024-02-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26279
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  6. Article ; Online: Determining the SARS-CoV-2 serological immunoassay test performance indices based on the test results frequency distribution.

    Habibzadeh, Farrokh / Habibzadeh, Parham / Yadollahie, Mahboobeh / Sajadi, Mohammad M

    Biochemia medica

    2022  Volume 32, Issue 2, Page(s) 20705

    Abstract: Introduction: Coronavirus disease 2019 (COVID-19) is known to induce robust antibody response in most of the affected individuals. The objective of the study was to determine if we can harvest the test sensitivity and specificity of a commercial ... ...

    Abstract Introduction: Coronavirus disease 2019 (COVID-19) is known to induce robust antibody response in most of the affected individuals. The objective of the study was to determine if we can harvest the test sensitivity and specificity of a commercial serologic immunoassay merely based on the frequency distribution of the SARS-CoV-2 immunoglobulin (Ig) G concentrations measured in a population-based seroprevalence study.
    Materials and methods: The current study was conducted on a subset of a previously published dataset from the canton of Geneva. Data were taken from two non-consecutive weeks (774 samples from May 4-9, and 658 from June 1-6, 2020). Assuming that the frequency distribution of the measured SARS-CoV-2 IgG is binormal (an educated guess), using a non-linear regression, we decomposed the distribution into its two Gaussian components. Based on the obtained regression coefficients, we calculated the prevalence of SARS-CoV-2 infection, the sensitivity and specificity, and the most appropriate cut-off value for the test. The obtained results were compared with those obtained from a validity study and a seroprevalence population-based study.
    Results: The model could predict more than 90% of the variance observed in the SARS-CoV-2 IgG distribution. The results derived from our model were in good agreement with the results obtained from the seroprevalence and validity studies. Altogether 138 of 1432 people had SARS-CoV-2 IgG ≥ 0.90, the cut-off value which maximized the Youden's index. This translates into a true prevalence of 7.0% (95% confidence interval 5.4% to 8.6%), which is in keeping with the estimated prevalence of 7.7% derived from our model. Our model can provide the true prevalence.
    Conclusions: Having an educated guess about the distribution of test results, the test performance indices can be derived with acceptable accuracy merely based on the test results frequency distribution without the need for conducting a validity study and comparing the test results against a gold-standard test.
    MeSH term(s) Antibodies, Viral ; COVID-19/diagnosis ; COVID-19/epidemiology ; Humans ; Immunoassay/methods ; Immunoglobulin G ; SARS-CoV-2 ; Sensitivity and Specificity ; Seroepidemiologic Studies
    Chemical Substances Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2022-06-21
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 1208725-7
    ISSN 1846-7482 ; 1330-0962
    ISSN (online) 1846-7482
    ISSN 1330-0962
    DOI 10.11613/BM.2022.020705
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4273: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Discordant Antigenic Properties of Soluble and Virion SARS-CoV-2 Spike Proteins.

    Kumar, Sameer / Dasgupta, Souradip / Sajadi, Mohammad M / Snyder, Greg A / DeVico, Anthony L / Ray, Krishanu

    Viruses

    2024  Volume 16, Issue 3

    Abstract: Efforts to develop vaccine and immunotherapeutic countermeasures against the COVID-19 pandemic focus on targeting the trimeric spike (S) proteins of SARS-CoV-2. Vaccines and therapeutic design strategies must impart the characteristics of virion S from ... ...

    Abstract Efforts to develop vaccine and immunotherapeutic countermeasures against the COVID-19 pandemic focus on targeting the trimeric spike (S) proteins of SARS-CoV-2. Vaccines and therapeutic design strategies must impart the characteristics of virion S from historical and emerging variants onto practical constructs such as soluble, stabilized trimers. The virus spike is a heterotrimer of two subunits: S1, which includes the receptor binding domain (RBD) that binds the cell surface receptor ACE2, and S2, which mediates membrane fusion. Previous studies suggest that the antigenic, structural, and functional characteristics of virion S may differ from current soluble surrogates. For example, it was reported that certain anti-glycan, HIV-1 neutralizing monoclonal antibodies bind soluble SARS-CoV-2 S but do not neutralize SARS-CoV-2 virions. In this study, we used single-molecule fluorescence correlation spectroscopy (FCS) under physiologically relevant conditions to examine the reactivity of broadly neutralizing and non-neutralizing anti-S human monoclonal antibodies (mAbs) isolated in 2020. Binding efficiency was assessed by FCS with soluble S trimers, pseudoviruses and inactivated wild-type virions representing variants emerging from 2020 to date. Anti-glycan mAbs were tested and compared. We find that both anti-S specific and anti-glycan mAbs exhibit variable but efficient binding to a range of stabilized, soluble trimers. Across mAbs, the efficiencies of soluble S binding were positively correlated with reactivity against inactivated virions but not pseudoviruses. Binding efficiencies with pseudoviruses were generally lower than with soluble S or inactivated virions. Among neutralizing mAbs, potency did not correlate with binding efficiencies on any target. No neutralizing activity was detected with anti-glycan antibodies. Notably, the virion S released from membranes by detergent treatment gained more efficient reactivity with anti-glycan, HIV-neutralizing antibodies but lost reactivity with all anti-S mAbs. Collectively, the FCS binding data suggest that virion surfaces present appreciable amounts of both functional and nonfunctional trimers, with neutralizing anti-S favoring the former structures and non-neutralizing anti-glycan mAbs binding the latter. S released from solubilized virions represents a nonfunctional structure bound by anti-glycan mAbs, while engineered soluble trimers present a composite structure that is broadly reactive with both mAb types. The detection of disparate antigenicity and immunoreactivity profiles in engineered and virion-associated S highlight the value of single-virus analyses in designing future antiviral strategies against SARS-CoV-2.
    MeSH term(s) Humans ; Spike Glycoprotein, Coronavirus ; SARS-CoV-2 ; Pandemics ; COVID-19 ; Antibodies, Neutralizing ; HIV Antibodies/analysis ; Antibodies, Monoclonal ; HIV-1 ; Virion/metabolism ; Antibodies, Viral/chemistry
    Chemical Substances spike protein, SARS-CoV-2 ; Spike Glycoprotein, Coronavirus ; Antibodies, Neutralizing ; HIV Antibodies ; Antibodies, Monoclonal ; Antibodies, Viral
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16030407
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  8. Article: Correction: The expression changes of transcription factors including ANKZF1, LEF1, CASZ1, and ATOH1 as a predictor of survival rate in colorectal cancer: a large-scale analysis.

    Sajadi, Manizheh / Fazilati, Mohammad / Nazem, Habibollah / Mahdevar, Mohammad / Ghaedi, Kamran

    Cancer cell international

    2023  Volume 23, Issue 1, Page(s) 53

    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2091573-1
    ISSN 1475-2867
    ISSN 1475-2867
    DOI 10.1186/s12935-023-02878-x
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  9. Article: Greener pathway toward the synthesis of lichen-based ZnO@TiO

    Abdullah, Shorish M / Kolo, Kamal / Sajadi, S Mohammad

    Food science & nutrition

    2020  Volume 8, Issue 8, Page(s) 4044–4054

    Abstract: A green way is introduced to biosynthesis of ZnO@ ... ...

    Abstract A green way is introduced to biosynthesis of ZnO@TiO
    Language English
    Publishing date 2020-06-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703010-6
    ISSN 2048-7177
    ISSN 2048-7177
    DOI 10.1002/fsn3.1661
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  10. Article: Comparison of the mechanical characteristics of produced nanofibers by electrospinning process based on different collectors.

    Sheikhi, Sajjad / Ghassemi, Aazam / Sajadi, S Mohammad / Hashemian, Mohammad

    Heliyon

    2023  Volume 10, Issue 1, Page(s) e23841

    Abstract: Polymer nanofiber in nanofibrous membrane produced by electrospinning process can be employed in various fields such as medical engineering, environmental engineering, biotechnology, energy, tissue scaffolds, and protective clothing. In these ... ...

    Abstract Polymer nanofiber in nanofibrous membrane produced by electrospinning process can be employed in various fields such as medical engineering, environmental engineering, biotechnology, energy, tissue scaffolds, and protective clothing. In these applications, the mechanical properties of the nanofibrous membrane should be studied to get long-life durability. In the current study, nanofibers are obtained from electrospinning of polyacrylonitrile (PAN) solution in Dimethylformamide (DFM) solvent. Nanofibers are produced with disc, cylinder, wire drum, parallel bars and polygon collectors and their mechanical properties are examined and compared. For this study, a tensile testing machine with special jaws was applied. According to the Scanning Electron Microscope (SEM) images, the average diameter of the produced nanofibers ranges from 300 to 340 nm. In addition, nanofiber layers have a thickness of 0.03 mm. They were cut in the 10 × 25 mm
    Language English
    Publishing date 2023-12-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e23841
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