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  1. Book: Zhong yao ji sheng chong bing zhen zhi zhi nan

    Xu, Longqi

    2002  

    Title translation Handbook on diagnosis and treatment of major parasitic diseases.
    Author's details zhu bian Xu Longqi, Xue Chunliang
    MeSH term(s) Intestinal Diseases, Parasitic/diagnosis ; Intestinal Diseases, Parasitic/therapy
    Language Chinese
    Size 2, 3, 243 p. :, ill.
    Edition Di 1 ban.
    Publisher Beijing ke xue ji shu chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787530426517 ; 7530426516
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Book: Zhi wu wei sheng tai xue

    Mei, Ruhung / Xu, Weimin

    1998  

    Author's details Mei Ruhong, Xu Weimin zhu
    Keywords Plant ecophysiology. ; Plants/Microbiology.
    Language Chinese ; English
    Size 3, 3, 192 p. :, ill. ;, 26 cm.
    Edition Di 1 ban.
    Publisher Zhongguo nong ye chu ban she ; Xin hua shu dian Beijing fa xing suo fa xing
    Publishing place Beijing shi
    Document type Book
    Note Cheifly Chinese; some English, with added table of contents also in English. ; Includes bibliographical references (p. 185-186).
    ISBN 7109054543 ; 9787109054547
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: CD6

    Xu, Dan-Dan / Liu, Xiao-Qiang / Wu, Zhi-Sheng

    Journal of integrative neuroscience

    2024  Volume 23, Issue 3, Page(s) 55

    Abstract: Background: This study used bioinformatics combined with statistical methods to identify plasma biomarkers that can predict intracranial aneurysm (IA) rupture and provide a strong theoretical basis for the search for new IA rupture prevention methods.!## ...

    Abstract Background: This study used bioinformatics combined with statistical methods to identify plasma biomarkers that can predict intracranial aneurysm (IA) rupture and provide a strong theoretical basis for the search for new IA rupture prevention methods.
    Methods: We downloaded gene expression profiles in the GSE36791 and GSE122897 datasets from the Gene Expression Omnibus (GEO) database. Data were normalized using the "sva" R package and differentially expressed genes (DEGs) were identified using the "limma" R package. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were used for DEG function analysis. Univariate logistic regression analysis, least absolute shrinkage and selection operator (LASSO) regression modeling, and the support vector machine recursive feature elimination (SVM-RFE) algorithm were used to identify key biomarker genes. Data from GSE122897 and GSE13353 were extracted to verify our findings.
    Results: Eight co-DEG mRNAs were identified in the GSE36791 and GSE122897 datasets. Genes associated with inflammatory responses were clustered in the co-DEG mRNAs in IAs.
    Conclusions: The identified two-gene signature (
    MeSH term(s) Humans ; Receptors, CCR7/genetics ; Intracranial Aneurysm/genetics ; Algorithms ; Computational Biology ; Databases, Factual
    Chemical Substances Receptors, CCR7 ; CCR7 protein, human
    Language English
    Publishing date 2024-03-27
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2136427-8
    ISSN 0219-6352
    ISSN 0219-6352
    DOI 10.31083/j.jin2303055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6117: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Book: Taiwan ye sheng mu ben zhi wu

    Xu, Guoshi / Kong, Xianxin / Lü, Shengyou

    (Ke xue jiao yu zi liao cong shu ; 7)

    1984  

    Institution Taiwan. / Jiao yu ting
    Author's details [zhu bian Xu Guoshi ; bian ji Kong Xian xin ... et al. ; zhuan gao Xu Guoshi ... et al. ; she ying Lü Shengyou]
    Series title Ke xue jiao yu zi liao cong shu ; 7
    Keywords Woody plants
    Language Chinese
    Size 173 p. :, ill. (some col.) ;, 22 cm.
    Publisher Taiwan sheng zheng fu jiao yu ting
    Publishing place Taizhong Xian Wufeng
    Document type Book
    Note Nomencalture and index also in Latin; table of contents also in English. ; Cover title also in English: The wild woody plants of Taiwan. ; Includes indexes.
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: A MYB activator, DcMYB11c, regulates carrot anthocyanins accumulation in petiole but not taproot.

    Duan, Ao-Qi / Deng, Yuan-Jie / Tan, Shan-Shan / Xu, Zhi-Sheng / Xiong, Ai-Sheng

    Plant, cell & environment

    2023  Volume 46, Issue 9, Page(s) 2794–2809

    Abstract: The first domesticated carrots were thought to be purple carrots rich in anthocyanins. The anthocyanins biosynthesis in solid purple carrot taproot was regulated by DcMYB7 within ... ...

    Abstract The first domesticated carrots were thought to be purple carrots rich in anthocyanins. The anthocyanins biosynthesis in solid purple carrot taproot was regulated by DcMYB7 within P
    MeSH term(s) Anthocyanins/metabolism ; Daucus carota/genetics ; Daucus carota/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Pigmentation/genetics ; Gene Editing ; Gene Expression Regulation, Plant
    Chemical Substances Anthocyanins ; Plant Proteins
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 391893-2
    ISSN 1365-3040 ; 0140-7791
    ISSN (online) 1365-3040
    ISSN 0140-7791
    DOI 10.1111/pce.14653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 80/729: Show issues

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  6. Article: Generating colorful carrot germplasm through metabolic engineering of betalains pigments.

    Deng, Yuan-Jie / Duan, Ao-Qi / Liu, Hui / Wang, Ya-Hui / Zhang, Rong-Rong / Xu, Zhi-Sheng / Xiong, Ai-Sheng

    Horticulture research

    2023  Volume 10, Issue 4, Page(s) uhad024

    Abstract: Betalains are tyrosine-derived plant pigments exclusively found in the Caryophyllales order and some higher fungi and generally classified into two groups: red-violet betacyanins and yellow-orange betaxanthins. Betalains attract great scientific and ... ...

    Abstract Betalains are tyrosine-derived plant pigments exclusively found in the Caryophyllales order and some higher fungi and generally classified into two groups: red-violet betacyanins and yellow-orange betaxanthins. Betalains attract great scientific and economic interest because of their relatively simple biosynthesis pathway, attractive colors and health-promoting properties. Co-expressing two core genes
    Language English
    Publishing date 2023-02-14
    Publishing country England
    Document type Journal Article
    ISSN 2662-6810
    ISSN 2662-6810
    DOI 10.1093/hr/uhad024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: DcGST1, encoding a glutathione S-transferase activated by DcMYB7, is the main contributor to anthocyanin pigmentation in purple carrot.

    Duan, Ao-Qi / Deng, Yuan-Jie / Tan, Shan-Shan / Liu, Shan-Shan / Liu, Hui / Xu, Zhi-Sheng / Shu, Sheng / Xiong, Ai-Sheng

    The Plant journal : for cell and molecular biology

    2023  Volume 117, Issue 4, Page(s) 1069–1083

    Abstract: The color of purple carrot taproots mainly depends on the anthocyanins sequestered in the vacuoles. Glutathione S-transferases (GSTs) are key enzymes involved in anthocyanin transport. However, the precise mechanism of anthocyanin transport from the ... ...

    Abstract The color of purple carrot taproots mainly depends on the anthocyanins sequestered in the vacuoles. Glutathione S-transferases (GSTs) are key enzymes involved in anthocyanin transport. However, the precise mechanism of anthocyanin transport from the cytosolic surface of the endoplasmic reticulum (ER) to the vacuoles in carrots remains unclear. In this study, we conducted a comprehensive analysis of the carrot genome, leading to the identification of a total of 41 DcGST genes. Among these, DcGST1 emerged as a prominent candidate, displaying a strong positive correlation with anthocyanin pigmentation in carrot taproots. It was highly expressed in the purple taproot tissues of purple carrot cultivars, while it was virtually inactive in the non-purple taproot tissues of purple and non-purple carrot cultivars. DcGST1, a homolog of Arabidopsis thaliana TRANSPARENT TESTA 19 (TT19), belongs to the GSTF clade and plays a crucial role in anthocyanin transport. Using the CRISPR/Cas9 system, we successfully knocked out DcGST1 in the solid purple carrot cultivar 'Deep Purple' ('DPP'), resulting in carrots with orange taproots. Additionally, DcMYB7, an anthocyanin activator, binds to the DcGST1 promoter, activating its expression. Compared with the expression DcMYB7 alone, co-expression of DcGST1 and DcMYB7 significantly increased anthocyanin accumulation in carrot calli. However, overexpression of DcGST1 in the two purple carrot cultivars did not change the anthocyanin accumulation pattern or significantly increase the anthocyanin content. These findings improve our understanding of anthocyanin transport mechanisms in plants, providing a molecular foundation for improving and enhancing carrot germplasm.
    MeSH term(s) Anthocyanins/metabolism ; Daucus carota/genetics ; Glutathione Transferase/genetics ; Glutathione Transferase/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Gene Expression Regulation, Plant ; Pigmentation/genetics
    Chemical Substances Anthocyanins ; Glutathione Transferase (EC 2.5.1.18) ; Plant Proteins
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.16539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 6071: Show issues

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  8. Article ; Online: A MYB activator, DcMYB11c, regulates carrot anthocyanins accumulation in petiole but not taproot

    Duan, Ao‐Qi / Deng, Yuan‐Jie / Tan, Shan‐Shan / Xu, Zhi‐Sheng / Xiong, Ai‐Sheng

    Plant, Cell & Environment. 2023 Sept., v. 46, no. 9 p.2794-2809

    2023  

    Abstract: The first domesticated carrots were thought to be purple carrots rich in anthocyanins. The anthocyanins biosynthesis in solid purple carrot taproot was regulated by DcMYB7 within P₃ region containing a gene cluster of six DcMYBs. Here, we described a MYB ...

    Abstract The first domesticated carrots were thought to be purple carrots rich in anthocyanins. The anthocyanins biosynthesis in solid purple carrot taproot was regulated by DcMYB7 within P₃ region containing a gene cluster of six DcMYBs. Here, we described a MYB gene within the same region, DcMYB11c, which was highly expressed in the purple pigmented petioles. Overexpression of DcMYB11c in ‘Kurodagosun’ (KRDᴳ, orange taproot carrot with green petioles) and ‘Qitouhuang’ (QTHᴳ, yellow taproot carrot with green petioles) resulted in deep purple phenotype in the whole carrot plants indicating anthocyanins accumulation. Knockout of DcMYB11c in ‘Deep Purple’ (DPPᴾ, purple taproot carrot with purple petioles) through CRISPR/Cas9‐based genome editing resulted in pale purple phenotype due to the dramatic decrease of anthocyanins content. DcMYB11c could induce the expression of DcbHLH3 and anthocyanins biosynthesis genes to jointly promote anthocyanins biosynthesis. Yeast one‐hybrid assay (Y1H) and dual‐luciferase reporter assay (LUC) revealed that DcMYB11c bound to the promoters of DcUCGXT1 and DcSAT1 and directly activated the expression of DcUCGXT1 and DcSAT1 responsible for anthocyanins glycosylation and acylation, respectively. Three transposons were present in the carrot cultivars with purple petioles but not in the carrot cultivars with green petioles. We revealed the core factor, DcMYB11c, involved in anthocyanins pigmentation in carrot purple petioles. This study provides new insights into precise regulation mechanism underlying anthocyanins biosynthesis in carrot. The orchestrated regulation mechanism in carrot might be conserved across the plant kingdom and useful for other researchers working on anthocyanins accumulation in different tissues.
    Keywords acylation ; anthocyanins ; bioluminescence assay ; biosynthesis ; carrots ; cultivars ; environment ; glycosylation ; multigene family ; petioles ; phenotype ; pigmentation ; tap roots ; transposons ; yeasts
    Language English
    Dates of publication 2023-09
    Size p. 2794-2809.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 391893-2
    ISSN 1365-3040 ; 0140-7791
    ISSN (online) 1365-3040
    ISSN 0140-7791
    DOI 10.1111/pce.14653
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  9. Article ; Online: Genome-Wide Identification and Evolution Analysis of R2R3-MYB Gene Family Reveals S6 Subfamily R2R3-MYB Transcription Factors Involved in Anthocyanin Biosynthesis in Carrot.

    Duan, Ao-Qi / Tan, Shan-Shan / Deng, Yuan-Jie / Xu, Zhi-Sheng / Xiong, Ai-Sheng

    International journal of molecular sciences

    2022  Volume 23, Issue 19

    Abstract: The taproot of purple carrot accumulated rich anthocyanin, but non-purple carrot did not. MYB transcription factors (TFs) condition anthocyanin biosynthesis in many plants. Currently, genome-wide identification and evolution analysis of R2R3-MYB gene ... ...

    Abstract The taproot of purple carrot accumulated rich anthocyanin, but non-purple carrot did not. MYB transcription factors (TFs) condition anthocyanin biosynthesis in many plants. Currently, genome-wide identification and evolution analysis of R2R3-MYB gene family and their roles involved in conditioning anthocyanin biosynthesis in carrot is still limited. In this study, a total of 146 carrot R2R3-MYB TFs were identified based on the carrot transcriptome and genome database and were classified into 19 subfamilies on the basis of R2R3-MYB domain. These R2R3-MYB genes were unevenly distributed among nine chromosomes, and
    MeSH term(s) Anthocyanins/metabolism ; Daucus carota/genetics ; Daucus carota/metabolism ; Gene Expression Regulation, Plant ; Genes, myb ; Phylogeny ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
    Chemical Substances Anthocyanins ; Plant Proteins ; Transcription Factors
    Language English
    Publishing date 2022-10-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms231911859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The high-quality genome of Cryptotaenia japonica and comparative genomics analysis reveals anthocyanin biosynthesis in Apiaceae.

    Liu, Hui / Zhang, Jia-Qi / Zhang, Rong-Rong / Zhao, Qin-Zheng / Su, Li-Yao / Xu, Zhi-Sheng / Cheng, Zong-Ming Max / Tan, Guo-Fei / Xiong, Ai-Sheng

    The Plant journal : for cell and molecular biology

    2024  

    Abstract: Cryptotaenia japonica, a traditional medicinal and edible vegetable crops, is well-known for its attractive flavors and health care functions. As a member of the Apiaceae family, the evolutionary trajectory and biological properties of C. japonica are ... ...

    Abstract Cryptotaenia japonica, a traditional medicinal and edible vegetable crops, is well-known for its attractive flavors and health care functions. As a member of the Apiaceae family, the evolutionary trajectory and biological properties of C. japonica are not clearly understood. Here, we first reported a high-quality genome of C. japonica with a total length of 427 Mb and N50 length 50.76 Mb, was anchored into 10 chromosomes, which confirmed by chromosome (cytogenetic) analysis. Comparative genomic analysis revealed C. japonica exhibited low genetic redundancy, contained a higher percentage of single-cope gene families. The homoeologous blocks, K
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.16628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 6071: Show issues

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