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Article ; Online: The Combined Effect of Beetroot Peel Extract, Chilling, and Vacuum Packaging on the Shelf-Life of Deccan Mahseer (Tor khudree) Steaks

Maqbool, Hafsa / Abubacker, Zynudheen / Safeena, Muhammad P. / Azhar, Mudassir / Joshy, C.G.

Journal of Aquatic Food Product Technology. 2023 Jan. 02, v. 32, no. 1 p.1-12

2023

Abstract: The effect of beetroot peel extract (BPE) on the quality of vacuum-packed fresh mahseer steaks (Tor khudree) was evaluated under chilled conditions (2°C) over a period of 15 days. Liquid chromatography mass-spectrometry (LC-MS) analysis was used to ... ...

Abstract	The effect of beetroot peel extract (BPE) on the quality of vacuum-packed fresh mahseer steaks (Tor khudree) was evaluated under chilled conditions (2°C) over a period of 15 days. Liquid chromatography mass-spectrometry (LC-MS) analysis was used to quantify BPE for the characterization of phenolic and flavonoid compounds. The fish samples were analyzed for sensory, biochemical, and microbiological parameters. Treatments included the following: CtAP (control samples, untreated: air packed), CtVP (control samples, untreated: vacuum packed), and BtVP (vacuum packed, treated with BPE 20% v/v). When comparing CtAP and CtVP mahseer steaks to BtVP mahseer steaks, the total plate count was higher, followed by the Enterobacteriaceae count. Based on the changes in quality indices, beetroot peel extract treated steaks showed significant (P < 0.05) control over lipid oxidation and microbial growth compared to CtAP and CtVP steaks throughout the storage. As per the sensory analysis, air-packed steaks were found to have a shelf life of about 9 days; vacuum-packed steaks were found to be acceptable for 12 days, whereas beetroot peel extract treated vacuum-packed steaks were acceptable for 18 days. Consequently, vacuum-packaging in combination with BPE treatment was found to delay the spoilage phenomenon, thereby increasing the shelf life of mahseer steaks.
Keywords	Enterobacteriaceae ; air ; beets ; fish ; flavonoids ; foods ; lipid peroxidation ; liquid chromatography ; mass spectrometry ; microbial growth ; plate count ; sensory evaluation ; shelf life ; spoilage ; vacuum packaging ; Oxidation ; shelf-life ; LC-MS/MS ; phenolic compounds ; flavonoid compounds
Language	English
Dates of publication	2023-0102
Size	p. 1-12.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	1150134-0
ISSN	1547-0636 ; 1049-8850
ISSN (online)	1547-0636
ISSN	1049-8850
DOI	10.1080/10498850.2022.2150107
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Beta Blockade Prevents Cardiac Morphological and Molecular Remodelling in Experimental Uremia.

Chinnappa, Shanmugakumar / Maqbool, Azhar / Viswambharan, Hema / Mooney, Andrew / Denby, Laura / Drinkhill, Mark

International journal of molecular sciences

2023 Volume 25, Issue 1

Abstract: Heart failure and chronic kidney disease (CKD) share several mediators of cardiac pathological remodelling. Akin to heart failure, this remodelling sets in motion a vicious cycle of progressive pathological hypertrophy and myocardial dysfunction in CKD. ... ...

Abstract	Heart failure and chronic kidney disease (CKD) share several mediators of cardiac pathological remodelling. Akin to heart failure, this remodelling sets in motion a vicious cycle of progressive pathological hypertrophy and myocardial dysfunction in CKD. Several decades of heart failure research have shown that beta blockade is a powerful tool in preventing cardiac remodelling and breaking this vicious cycle. This phenomenon remains hitherto untested in CKD. Therefore, we set out to test the hypothesis that beta blockade prevents cardiac pathological remodelling in experimental uremia.
MeSH term(s)	Humans ; Rats ; Animals ; Rats, Wistar ; Metoprolol/pharmacology ; Heart Failure ; Renal Insufficiency, Chronic/drug therapy ; Hypertrophy ; Fibrosis
Chemical Substances	Metoprolol (GEB06NHM23)
Language	English
Publishing date	2023-12-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25010373
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The Effects of Gestational Diabetes on Fetus: A Surveillance Study.

Ejaz, Zahra / Azhar Khan, Ayesha / Sebghat Ullah, Syed / Aamir Hayat, Muhammad / Maqbool, Muhammad Arslan / Amin Baig, Asma

Cureus

2023 Volume 15, Issue 2, Page(s) e35103

Abstract: Introduction: Gestational diabetes is an intolerance to glucose diagnosed during pregnancy that goes away postpartum. Gestational diabetes may result in outcomes such as birth trauma, increased rates of cesarean sections, and macrosomia. This study aims ...

Abstract	Introduction: Gestational diabetes is an intolerance to glucose diagnosed during pregnancy that goes away postpartum. Gestational diabetes may result in outcomes such as birth trauma, increased rates of cesarean sections, and macrosomia. This study aims to determine the outcomes of gestational diabetes mellitus (GDM) on maternal and fetal health in a tertiary care hospital setting. Materials and methods: This is a retrospective study of 52 patients who presented with gestational diabetes mellitus (GDM) and were treated at Tentishev Satkynbai Memorial Asian Medical Institute, Kyrgyzstan, between April 2021 and January 2022. The information was taken from the medical records of the patients. The baby's age, the mother's body mass index (BMI), history of pregnancy, deaths, birth weight, and the number of births were all taken into account. Results: Out of all the cases during the study period at the Tentishev Satkynbai Memorial Asian Medical Institute, Kyrgyzstan, 52 were found to be complicated with gestational diabetes mellitus, which is 2.7% of the total deliveries. There was a significant difference found among both study groups in gestational age and history of GDM. The neonatal intensive care unit (NICU) admission rate of neonates born to GDM mothers was found to be significant with a difference of 10.9% (p < 0.0003), which is higher compared to the control group. Conclusion: Incidences of macrosomia, NICU admissions of preterm babies, and large for gestational age (LGA) and increased rates of hypertensive disorders were found among GDM pregnancies compared to control cases. The study shows higher rates of maternal and fetal/neonatal complications in females with GDM.
Language	English
Publishing date	2023-02-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.35103
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Knowledge, attitudes, and practices of vaccinators about expanded programs on immunization: a cross-sectional study.

Azhar, Sunia / Rashid, Laiba / Islam, Taskeen / Akhtar, Samar / Hopkins, Kathryn L / Sommers, Theresa / Ikram, Aamer / Anwer, Naveed / Maqbool, Nabeel Ahmed / Khan, Zakir / Ahmed, Naveed / Akhtar, Hashaam

Frontiers in public health

2024 Volume 12, Page(s) 1366378

Abstract: Introduction: The periodic evaluation of knowledge, attitudes, and practices (KAP) of healthcare workers, including vaccinators, concerning expanded programs on immunization (EPI) is very crucial for a better healthcare system. This study was carried ... ...

Abstract	Introduction: The periodic evaluation of knowledge, attitudes, and practices (KAP) of healthcare workers, including vaccinators, concerning expanded programs on immunization (EPI) is very crucial for a better healthcare system. This study was carried out to assess the KAP of vaccinators about the EPI, including cold storage of vaccines and their practices related to vaccine cold chain management. Method: A cross-sectional study was conducted from January 2022 to June 2022 among registered vaccinators in the twin cities (Islamabad and Rawalpindi) of Pakistan. A structured self-administered questionnaire (English and Urdu) was developed as per the Pakistan national EPI policy and strategic guidelines 2022 and World Health Organization (WHO) guidelines, as well as from earlier studies (Cronbach's alpha value of 0.734). The final questionnaire consisted of closed-ended questions in four sections, including sociodemographic information, knowledge (with dichotomous variables of yes/no), attitudes (with a 5-point Likert scale ranging from strongly agree to strongly disagree), and handling of vaccines and cold chain management. Completed questionnaires were entered into Microsoft Excel and then imported into SPSS version 25 for statistical analysis. Results: A total of 186 vaccinators completely filled out their questionnaires, with a 97.9% response rate. More than half of the participants (57.5%) had no training related to EPI. Most of the respondents had a moderate to poor level of knowledge regarding EPI. The overall attitude was positive, and 57% of the participants strongly agreed that the national immunization programs can significantly contribute to the decrease in morbidity and mortality rates among children. In the current study, participants showed good practices toward EPI, vaccine storage, and cold chain management. The majority (93.5%) of the participants checked the expiry of vaccines at regular intervals to maintain the first expiry first out (FEFO) in their healthcare setting. Discussion: In conclusion, most of the vaccinators had moderate to poor knowledge, a positive attitude, and good practices toward EPI, vaccine cold storage, and cold chain management. Lack of training among vaccinators on EPI was also observed. These findings have suggested that continuous training, education, and regular supervision of vaccinators in EPI are important for maximum immunization effectiveness and coverage.
MeSH term(s)	Child ; Humans ; Cross-Sectional Studies ; Health Knowledge, Attitudes, Practice ; Immunization ; Vaccines ; Immunization Programs
Chemical Substances	Vaccines
Language	English
Publishing date	2024-03-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2024.1366378
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Article ; Online: Parenting Practices and Aggression in Childhood Behaviour Disorders

Fatima Rahman / Shazia Maqbool / Anam Ali / Talha Mahmud / Hina Azhar / Aisha Farid

Pakistan Armed Forces Medical Journal, Vol 73, Iss

2023 Volume 1

Abstract: Objective: To determine the association between parenting practices and aggression in children with behaviour disorders. Study Design: Cross-sectional study. Place and Duration of Study: Children Hospital and Institute of Child Health, Lahore Pakistan, ... ...

Abstract	Objective: To determine the association between parenting practices and aggression in children with behaviour disorders. Study Design: Cross-sectional study. Place and Duration of Study: Children Hospital and Institute of Child Health, Lahore Pakistan, from Nov 2020 to Jan 2021. Methodology: Parents of children and eighty-five children between the ages of 3 to 12 years with the diagnosis of behaviour disorders (autism spectrum disorder, attention deficit hyperactive disorder, social communication disorder) and showing aggressive behaviour were enrolled. The multidimensional assessment of parenting scale was used to assess positive(proactive parenting, positive reinforcement, warmth and supportiveness) and negative (hostility, lax control, physical control) parenting practices. The modified overt aggression scale was used to assess aggression, including verbal aggression,aggression against property, auto-aggression (towards self), and physical aggression (towards others). Correlation and multiple regression analysis were done. Results: Among negative practices, it was found that leniency and inconsistent parenting (lax control) was significant positive predictor of aggression (p<0.01) in children with behaviour disorders. Supportiveness was a significant negative predictor of verbal aggression (p<0.01), while physical control positively predicted total aggression (p<0.05). Among positive parenting practices, positive reinforcement decreased auto aggression (p<0.05) in children with behaviour disorders. Lower maternal education correlated with more aggressive behaviours (p<0.05) in these children. Conclusion: Negative parenting practices may lead to aggression in children with behaviour disorders. While positive reinforcement by parents may encourage less self-harm in these children and help improve their behaviour problems.
Keywords	Aggression ; Attention deficit hyperactive disorder (ADHD) ; Autism spectrum disorder (ASD) ; Childhood behavior disorders ; Parenting practices ; Social communication disorder (SCD) ; Medicine ; R ; Medicine (General) ; R5-920
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Army Medical College Rawalpindi
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Beta Blockade Prevents Cardiac Morphological and Molecular Remodelling in Experimental Uremia

Shanmugakumar Chinnappa / Azhar Maqbool / Hema Viswambharan / Andrew Mooney / Laura Denby / Mark Drinkhill

International Journal of Molecular Sciences, Vol 25, Iss 1, p

2023 Volume 373

Abstract	Heart failure and chronic kidney disease (CKD) share several mediators of cardiac pathological remodelling. Akin to heart failure, this remodelling sets in motion a vicious cycle of progressive pathological hypertrophy and myocardial dysfunction in CKD. Several decades of heart failure research have shown that beta blockade is a powerful tool in preventing cardiac remodelling and breaking this vicious cycle. This phenomenon remains hitherto untested in CKD. Therefore, we set out to test the hypothesis that beta blockade prevents cardiac pathological remodelling in experimental uremia. Wistar rats had subtotal nephrectomy or sham surgery and were followed up for 10 weeks. The animals were randomly allocated to the beta blocker metoprolol (10 mg/kg/day) or vehicle. In vivo and in vitro cardiac assessments were performed. Cardiac tissue was extracted, and protein expression was quantified using immunoblotting. Histological analyses were performed to quantify myocardial fibrosis. Beta blockade attenuated cardiac pathological remodelling in nephrectomised animals. The echocardiographic left ventricular mass and the heart weight to tibial length ratio were significantly lower in nephrectomised animals treated with metoprolol. Furthermore, beta blockade attenuated myocardial fibrosis associated with subtotal nephrectomy. In addition, the Ca ++ - calmodulin-dependent kinase II (CAMKII) pathway was shown to be activated in uremia and attenuated by beta blockade, offering a potential mechanism of action. In conclusion, beta blockade attenuated hypertrophic signalling pathways and ameliorated cardiac pathological remodelling in experimental uremia. The study provides a strong scientific rationale for repurposing beta blockers, a tried and tested treatment in heart failure, for the benefit of patients with CKD.
Keywords	beta blocker ; cardiac remodelling ; CKD ; uremia ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	610
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Assessment of Children with Cerebral Palsy Using Common Brief Core Set of International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY)

Ammara Hina / Shazia Maqbool / Hina Azhar / Saba Fatima / Aisha Farid / Ehsan Ullah

Pakistan Armed Forces Medical Journal, Vol 73, Iss

2023 Volume 1

Abstract: Objective: To assess children with cerebral palsy using the Common Brief Core Set of International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY). Study Design: Cross-sectional study Place and Duration of Study: ... ...

Abstract	Objective: To assess children with cerebral palsy using the Common Brief Core Set of International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY). Study Design: Cross-sectional study Place and Duration of Study: Children Hospital & Institute of Child Health, Lahore Pakistan, from Nov 2020 to Jan 2021. Methodology: Fifty-nine children with cerebral palsy (CP) aged 0-18 years were included. Common Brief Core Set of International Classification of Functioning, Disability, and Health in Children and Youth (ICF-CY) was administered to children with cerebral palsy to assess their functional status. Strengths and weaknesses in body structure, body function,activity and participation and environmental factors were evaluated using the Common Brief Core Set of ICF-CY. Results: The majority of study participants were 38(64.4%), were spastic quadriplegic. Periventricular leukomalacia was noted in 36(67.9%) cases on MRI brain. Moderate to severe impairment was noted in body functions like intellectual function 46(78%). In addition, 26(44.1%) children with cerebral palsy had mild to moderate impairment in walking, while 4(6.8 %) could walk without any impairment. Social attitudes, construct, and design of buildings were the major barriers affecting the functionality of children with cerebral palsy. Conclusion: It was found that the Common Brief Core Set of ICF-CY in children with different types of cerebral palsy is a useful tool for assessing their functional level. Keywords: Cerebral Palsy, Common Brief Core Set, Disability, Health in Children and Youth (ICF-CY), International Classification of Functioning.
Keywords	Cerebral Palsy ; Common Brief Core Set ; Disability ; Health in Children and Youth (ICF-CY) ; International Classification of Functioning ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Army Medical College Rawalpindi
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Effect of beetroot peel dip treatment on the quality preservation of Deccan mahseer (Tor khudree) steaks during frozen storage (-18°C)

Maqbool, H. / Safeena, M. P. / Abubacker, Z. / Azhar, M. / Kumar, S.

LWT - food science and technology

2021 Volume 151, Issue -, Page(s) 112222

Language	English
Document type	Article
ZDB-ID	2169058-3
ISSN	0023-6438
Database	Current Contents Nutrition, Environment, Agriculture

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Article ; Online: Impact of Screen Media Usage on Early Childhood Development

Muneeba Malik / Shazia Maqbool / Anam Ali / Hina Azhar / Ehsan Ullah / Aisha Farid Khan

Pakistan Armed Forces Medical Journal, Vol 72, Iss

2022 Volume 6

Abstract: Objective: To see the impact of screen media usage on early childhood development. Study Design: Cross-sectional study. Place and Duration of study: Developmental Behavioural Paediatrics Department, Children’s Hospital and Institute of Child Health, ... ...

Abstract	Objective: To see the impact of screen media usage on early childhood development. Study Design: Cross-sectional study. Place and Duration of study: Developmental Behavioural Paediatrics Department, Children’s Hospital and Institute of Child Health, Lahore Pakistan, from Oct to Dec 2020. Methodology: This study included 100 children with an age range between 15-36 months and divided into two groups. Group-1 was children with communication behaviour disorders (CBD) (n=50), and Group-2 was typically developing (TD)children (n=50). ShaMaq Developmental Screening Tool (SDST) was administered to children to screen their development.Childhood behaviours were rated on a scale of 0-10 on a Behaviour rating scale. Results: Children with CBD had poor eye contact, response to names, poor imitation, poor pointing and poor one-step command following (p<0.001) compared to typically developing children. Children with CBD had poor eating habits (p<0.01),were more restless (p<0.001), and had a developmental delay (p<0.001) on SDST as compared to the other group. In children with CBD, the extent of screen media exposure was significantly correlated with restlessness (p<0.05) and poor pointing(p<0.01). Conclusion: Exposure to screen media at an early age and prolonged use of screens can lead to adverse developmental outcomes and behaviour issues in children. This is more evident in children with CBD than in typically developing children.
Keywords	Communication behaviour disorder ; Early childhood development ; ShaMaq developmental screening tool ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Army Medical College Rawalpindi
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Effect of beetroot peel dip treatment on the quality preservation of Deccan mahseer (Tor khudree) steaks during frozen storage (−18 °C)

Maqbool, Hafsa / Safeena, Muhammed P. / Abubacker, Zynudheen / Azhar, Mudassir / Kumar, Sathish

Lebensmittel-Wissenschaft + [i.e. und] Technologie. 2021 Nov., v. 151

2021

Abstract: The effects of dip treatment with beetroot peel extract on the quality of mahseer steaks during frozen storage (−18 °C) for 180 days were analysed. Prior to the dip treatment of steaks, the antioxidant properties of the extract were evaluated by in-vitro ...

Abstract	The effects of dip treatment with beetroot peel extract on the quality of mahseer steaks during frozen storage (−18 °C) for 180 days were analysed. Prior to the dip treatment of steaks, the antioxidant properties of the extract were evaluated by in-vitro assays following the standard protocol. Beetroot peel extract was further evaluated for the characterisation of phenolic and flavanoid compounds by LC-MS/MS analysis. Beetroot peel extract (20 %, v/v) was used for the dip treatment based on the in-vitro antioxidant assay and preliminary sensory analysis. Quality changes in terms of chemical characteristics, drip loss, microbiological and sensory characteristics were examined at regular intervals of 30 days. A marked antioxidant and antimicrobial effect (P < 0.05) of beetroot peel extract could be detected in limiting the lipid oxidation and microbial growth in fish steaks during frozen storage. As per the scores of sensory analysis, control steaks had a shelf-life of about 5 months, whereas the BPE treated steaks were found to be acceptable for more than 6 months. Therefore, beetroot peel treatment exhibited positive effect on retarding the spoilage, thereby increasing shelf-life of mahseer steaks during frozen storage.
Keywords	antimicrobial properties ; antioxidants ; beets ; drip loss ; fish ; frozen storage ; lipid peroxidation ; microbial growth ; sensory evaluation ; shelf life ; spoilage
Language	English
Dates of publication	2021-11
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	241369-3
ISSN	0460-1173 ; 0023-6438
ISSN	0460-1173 ; 0023-6438
DOI	10.1016/j.lwt.2021.112222
Database	NAL-Catalogue (AGRICOLA)

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